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| 1 | A new unconventional HLA-A2-restricted epitope from HBV core protein elicits antiviral cytotoxic T lymphocytes显示文摘细胞毒素的 T 房间(CTL ) 在肝炎 B 的控制起一个关键作用病毒(HBV ) 感染和病毒的清理。然而,大多数识别 CTL epitopes 从遗传型 A 和 D 的 HBV 被导出,并且很少在在亚洲更流行的遗传型 B 和 C 的病毒被定义。因为 HBV 核心蛋白质(HBc ) 是最保守、产生免疫性的部件,在这研究,我们使用了盖住 HBc 屏蔽并且识别特定的 CTL epitopes 的一个重叠 9-mer 肽水池。异乎寻常的 HLA-A2-restricted epitope HBc141149 被结晶化分析发现,在结构上描绘了。immunogenicity 和 anti-HBV 活动进一步在 HBV 和 HLA-A2 被决定转基因的老鼠。最后,我们证明在 HBc141149 epitope 的变化与病毒的参数被联系,在 HBV 的疾病前进感染了病人。我们的数据因此提供卓见进这异乎寻常的 epitope 绑定的结构特征给 MHC-I 分子,以及 epitope 特定的 CTL 活动在 HBV 安排 T 房间反应和有免疫力的避免感染的病人。 | Lu Sun Yu Zhang Bao Zhao Mengmeng Deng Jun Liu Xin Li Junwei Hou Mingming Gui Shuijun Zhang Xiaodong Li George F. Gao Songdong Meng | 2014 | Protein & Cell2014，5，4： | 7 |
| 2 | eGPS 1.0: comprehensive software for multi-omic and evolutionary analyses显示文摘It has become increasingly challenging for researchers to analyze the exponentially expanding amount of multi-omic data.Here,we describe multi-functional software named evolutionary GenotypePhenotype Systems(eGPS)that enables users to perform comprehensive multiomic and evolutionary analyses.The eGPS combines the power of cloud computing and the advantage of desktop application,has a user-friendly graphic interface and is highly interactive. | Dalang Yu Lili Dong Fangqi Yan Hailong Mu Bixia Tang Xiao Yang Tao Zeng Qing Zhou Feng Gao Zhonghuang Wang Ziqian Hao Hongen Kang Yi Zheng Hongwei Huang Yuzhang Wei Wei Pan Yaochen Xu Junwei Zhu Shilei Zhao Ciran Wang Pengyu Wang Long Dai Mushan Li Li Lan Yiwei Wang Hua Chen Yi-Xue Li Yun-Xin Fu Zhen Shao Yiming Bao Fangqing Zhao Luo-Nan Chen Guo-Qing Zhang Wenming Zhao Haipeng Li | 2019 | National Science Review2019，6，5： | 4 |
| 3 | Feedback control design with vibration suppression for flexible air-breathing hypersonic vehicles显示文摘This paper investigates the problem of feedback control design with vibration suppression for a flexible air-breathing hypersonic vehicle(FAHV).FAHV includes intricate coupling between the engine and flight dynamics,as well as complex interplay between flexible and rigid modes,which results in an intractable system for the control design.In this paper,a longitudinal model,which is described by a coupled system of ordinary diferential equations(ODEs)and partial diferential equations(PDEs),is adopted.Firstly,a linearized ODE model for the rigid part is established around the trim condition,while vibration of the fuselage is described by PDEs.Secondly,based on the Lyapunov direct method,a control law via ODE state feedback and PDE boundary output feedback is designed for the system such that the closed-loop exponential stability is ensured.Finally,simulation results are given to illustrate the efectiveness of the proposed design method. | GAO Yan WU HuaiNing WANG JunWei GUO Lei | 2014 | Science China(Information Sciences)2014，57，3： | 3 |
| 4 | Electricity Services Based Dependability Model of Power Grid Communication Networking显示文摘The technology of Ultra-High Voltage(UHV) transmission requires higher dependability for electric power grid. Power Grid Communication Networking(PGCN),the fundamental information infrastructure,severs data transmission including control signal,protection signal,and common data services. Dependability is the necessary requirement to ensure services timely and accurately. Dependability analysis aims to predicate operation status and provide suitable strategies getting rid of the potential dangers. Due to the dependability of PGCN may be affected by external environment,devices quality,implementation strategies,and so on,the scale explosion and the structure complexity make the PGCN's dependability much challenging. In this paper,with the observation of interdependency between power grid and PGCN,we propose an electricity services based dependability analysis model of PGCN. The model includes methods of analyzing its dependability and procedures of designing the dependable strategies. We respectively discuss the deterministic analysis method based on matrix analysis and stochastic analysis model based on stochastic Petri nets. | Jiye Wang Kun Meng Junwei Cao Zhen Chen Lingchao Gao Chuang Lin | 2014 | Tsinghua Science and Technology2014，19，2： | 3 |
| 5 | Effects of fruit thinning on ascorbate–glutathione cycle metabolism in black currants(Ribes nigrum L.)显示文摘To elucidate mechanisms regulating ascorbic acid(AsA) biosynthesis and accumulation in the fruit and leaves of black currants,As A and the activities of key enzymes in the ascorbate–glutathione(As A–GSH) cycle were measured from fruit set to fruit ripening during fruit thinning treatments of three common commercial black currant cultivars that differed in their As A levels:'Risager'(low),'Brodtrop'(medium) and 'Adelinia'(high).Treatments were 50% fruit reduction(50% of total fruit set) by hand,control was no thinning.Fruit thinning treatment significantly increased As A content in fruit of all three cultivars from weeks 2 to 8,significantly decreased As A content in leaves from weeks 3 to 8.Dehydroascorbate reductase and monodehydroascorbate reductase activities in fruit and leaves had a similar pattern,increasing during week 2,rose until they peaked in week 4.Ascorbate peroxidase activity in fruit in the thinning treatment was slightly lower than in the control.Fruit thinning was shown to be a good model to test As A biosynthesis regulation and accumulation in black currants.The results from our study provided strong evidence that As A–GSH cycle involved in As A synthesis and accumulation in fruit. | Dong Qin Lijuan Zhao Yu Gary Gao Fangxiao Li Shulei Li Junwei Huo Shuang Lou Peng Liu | 2017 | Journal of Forestry Research2017，28，5： | 3 |
| 6 | Digital holographic microscopy with phase-shift-free structured illumination显示文摘When structured illumination is used in digital holographic microscopy(DHM),each direction of the illumination fringe is required to be shifted at least three times to perform the phase-shifting reconstruction.In this paper,we propose a scheme for spatial resolution enhancement of DHM by using the structured illumination but without phase shifting.The structured illuminations of different directions,which are generated by a spatial light modulator,illuminate the sample sequentially in the object plane.The formed object waves interfere with a reference wave in an off-axis configuration,and a CCD camera records the generated hologram.After the object waves are reconstructed numerically,a synthetic aperture is performed by an iterative algorithm to enhance the spatial resolution.The resolution improvement of the proposed method is proved and demonstrated by both simulation and experiment. | Juanjuan Zheng Peng Gao Baoli Yao Tong Ye Ming Lei Junwei Min Dan Dan Yanlong Yang Shaohui Yan | 2014 | Photonics Research2014，2，3： | 2 |
| 7 | A novel gene encoding goose immunoglobulin λ light chain显示文摘 | Yongli Guo Mingchun Gao Junwei Wang | 2012 | Acta Biochimica et Biophysica Sinica2012，44，9： | 2 |
| 8 | Class attention network for image recognition显示文摘Visual attention has become a popular and widely used component for image recognition.Although various attention-based methods have been proposed and achieved relatively competitive results,it is observed that the semantic features of each class are likely to entangle with each other,and few studies focus on explicitly extracting category-aware features so far.To address this issue,this paper presents an attention-based image recognition method by using class-specific dictionary learning to disentangle the neural network’s outputs into class-dependent features,thus boosting their discrimination abilities.Specifically,we develop a class attention network(CANet)via integrating a simple yet effective class-specific attention encoding(CAE)module on the top of convolutional layers.Given the feature maps of the convolutional neural networks(CNNs),the CAE module learns a class-specific dictionary,which is leveraged to encode attention maps for each category.Then these attention maps are multiplied by the input features for classwise adaptive feature refinement.Extensive experiments on the PASCAL VOC 2007,PASCAL VOC 2012,MS COCO,and CUB-200-2011 datasets demonstrate the fabulous performance of our method on multiple visual recognition tasks,including multi-label image classification and fine-grained visual classification.In addition,the visualization results testify that CNNs can explicitly learn class-wise feature representations by introducing class-specific dictionary learning. | Gong CHENG Pujian LAI Decheng GAO Junwei HAN | 2023 | Science China(Information Sciences)2023，66，3： | 2 |
| 9 | A compact fluorescence/circular dichroism dual-modality probe for detection, differentiation, and detoxification of multiple heavy metal ions via bond-cleavage cascade reactions显示文摘Selective detection of multiple analytes in a compact design with dual-modality and theranostic features presents great challenges. Herein, we wish to report a coumarin-thiazolidine masked D-penicillamine based dual-modality fluorescent probe COU-DPA-1 for selective detection, differentiation, and detoxification of multiple heavy metal ions(Ag^(+), Hg^(2+), Cu^(2+)). The probe shows divergent fluorescence(FL)/circular dichroism(CD) responses via divergent bond-cleavage cascade reactions(metal ion promoted C-S cleavage and hydrolysis at two distinctive cleavage sites): FL “turn-off” and CD “turn-on” for Ag+(no hydrolysis), FL “turn-on” and CD “turn-off” for Hg^(+)(imine hydrolysis), and FL “self-threshold ratiometric” and CD “turn-off” for excess Cu^(2+)(lactone and imine hydrolysis), providing the first example of a fluorescence/CD dual-modality probe for multiple species with complimentary responses. Moreover, the bond-cleavage cascade reactions also lead to the formation of D-penicillamine heavy metal ion complexes for potential detoxification treatments. | Junwei Chen Na Wang Hongjuan Tong Chao Song Huijuan Ma Yajun Zhang Feng Gao Huan Xu Wei Wang Kaiyan Lou | 2021 | Chinese Chemical Letters2021，32，12： | 2 |
| 10 | Effects of GA3 and ABA on the respiratory pathways during the secondary bud burst in black currants显示文摘The effects of exogenous gibberellic acid(GA_3)and abscisic acid(ABA) on the total respiratory rate, percentages of total respiratory rate contributed by respiratory pathways [Embden-Meyerhof-Parnas Pathway(EMP),Pentose Phosphate Pathway(PPP), and Tricarboxylic Acid Cycle(TCA)], and conversion of starch to soluble sugars in the buds of black currants during secondary bud burst were investigated to determine the relationship between respiratory rates and secondary bud burst. ‘Adelinia', a black currant cultivar that is prone to secondary bud burst after the first harvest, was used in this study. Mature bushes of Adelinia were sprayed with 30 mg/L GA_3 and 50 mg/L ABA to manipulate bud burst. The results showed that exogenous applications of GA_3 and ABA had opposite effects on bud respiratory rate. Generally, GA_3 treatment increased the total respiratory rate and respiratory rate of the TCA and PPP, and the respiratory rates after GA_3 treatment were higher than those of control. While ABA treatment mostly decreased the total respiratory rate and the respiratory rate of TCA and PPP in buds in comparison to control. In terms of the percentage of the three respiratory rates in comparison to the total respiratory rate, GA_3 treatment significantly increased the percentage of TCA and PPP respiratory rate in comparison to the control(P \ 0.01), whereas ABA decreased the rates. GA_3 significantly increased the content of soluble sugars and decreased the starch content, while the starch content in buds after ABA treatment was significantly higher than that of the control. All results showed that PPP is a critical process for the second bud burst in black currants. While the EMP–TCA pathway is still dominant in bud respiration,provides a series of basic materials and energy(ATP). The conversion of starch to soluble sugars is essential for bud burst. Thus, we conclude that an energy shortage is a main contributor in ABA inhibition of the secondary bud burst of black currants. | Dong Qin Huanhuan Wang Chunhao Zhang Zeyuan Yu Yu Gary Gao Fuchun Xie Ning Hung Junwei Huo | 2017 | Journal of Forestry Research2017，28，4： | 2 |
| 11 | Nitrogen and Phosphorus Budget of a Polyculture System of Sea Cucumber(Apostichopus japonicus), Jellyfish(Rhopilema esculenta) and Shrimp(Fenneropenaeus chinensis)显示文摘The nitrogen(N) and phosphorus(P) budget and the ecological efficiency of a polyculture system of sea cucumber(Apostichopus japonicus), jellyfish(Rhopilema esculenta) and shrimp(Fenneropenaeus chinensis) were studied in a cofferdam, 120.2 ha in size. The nutrients were supplied by spring tide inflow. In total, 139600 kg N yr-1 and 9730 kg P yr-1 input to the system; while 118900 kg N yr-1 and 2840 kg P yr-1 outflowed from the system concurrently, thus the outflow was 85.7%(N) and 29.2%(P) of inflow. The production of N and P was 889.5 kg yr-1 and 49.28 kg yr-1(sea cucumber) and 204 kg yr-1 and 18.03 kg yr-1(jellyfish and shrimp), respectively. The utilization rate of N and P by polycultured animals was 7.8‰ and 6.9‰, respectively, 21.9% and 38% higher than that of monocultured sea cucumber. Our results indicated that the polyculture system was an efficient culture system of animals and a remediation system of coastal environment as well; it scavenged 14.3% and 70.8% of N and P, respectively. Such an ecological efficiency may be improved further by increasing either the stocking density or the size of sea cucumber or both. | LI Junwei DONG Shuanglin GAO Qinfeng ZHU Changbo | 2014 | Journal of Ocean University of China2014，13，3： | 2 |
| 12 | Adaptive fuzzy tracking control for a permanent magnet synchronous motor via hack-stepping approach 显示文摘 | YU Jinpeng GAO Junwei | 2010 | Mathematical Problems in Engineering2010，，： | 1 |
| 13 | 1-Pbps orbital angular momentum fibre-optic transmission显示文摘Space-division multiplexing(SDM),as a main candidate for future ultra-high capacity fibre-optic communications,needs to address limitations to its scalability imposed by computation-intensive multi-input multi-output(MIMO)digital signal processing(DSP)required to eliminate the crosstalk caused by optical coupling between multiplexed spatial channels.By exploiting the unique propagation characteristics of orbital angular momentum(OAM)modes in ring core fibres(RCFs),a system that combines SDM and C+L band dense wavelength-division multiplexing(DWDM)in a 34 km 7-core RCF is demonstrated to transport a total of 24960 channels with a raw(net)capacity of 1.223(1.02)Peta-bit s−1(Pbps)and a spectral efficiency of 156.8(130.7)bit s−1 Hz−1.Remarkably for such a high channel count,the system only uses fixed-size 4×4 MIMO DSP modules with no more than 25 time-domain taps.Such ultra-low MIMO complexity is enabled by the simultaneous weak coupling among fibre cores and amongst non-degenerate OAM mode groups within each core that have a fixed number of 4 modes.These results take the capacity of OAM-based fibre-optic communications links over the 1 Pbps milestone for the first time.They also simultaneously represent the lowest MIMO complexity and the 2nd smallest fibre cladding diameter amongst reported few-mode multicore-fibre(FM-MCF)SDM systems of>1 Pbps capacity.We believe these results represent a major step forward in SDM transmission,as they manifest the significant potentials for further up-scaling the capacity per optical fibre whilst keeping MIMO processing to an ultra-low complexity level and in a modularly expandable fashion. | Junyi Liu Jingxing Zhang Jie Liu Zhenrui Lin Zhenhua Li Zhongzheng Lin Junwei Zhang Cong Huang Shuqi Mo Lei Shen Shuqing Lin Yujie Chen Ran Gao Lei Zhang Xiaobo Lan Xinlun Cai Zhaohui Li Siyuan Yu | 2022 | Light(Science & Applications)2022，11，8： | 1 |
| 14 | Adap-tire fuzzy tracking control for the chaotic permanent magnet synchronous motor drive system via backstepping 显示文摘 | Jinpeng Yu Bing Chen Haisheng Yu Junwei Gao | 2011 | Non- linear Analysis-Real World Applications2011，12，1： | 1 |
| 15 | Towards a bright future:The versatile applications of organic solar cells显示文摘Due to the mechanical flexibility,light weight,aesthetics,absorption tunability and environmental friendliness,organic solar cells(OSCs)have superior application potential over their inorganic counterparts including silicon and perovskite solar cells(PSCs).Thanks to these benefits,the past decade have witnessed the rapid growth of flexible OSCs,semitransparent OSCs and indoor OSCs.In this progress report,we firstly overview the recent advance of the applications of the three promising OSCs.Subsequently,we sketch the critical points for the three classes of OSCs and highlight the efforts paid by the research community to address these issues.Besides,we discuss some popular strategies to afford great performance of each kind of OSC,respectively,and underline the corresponding breakthrough directions.Last but not least,we present the remaining challenges for advancing the commercial applications of these three classes of OSCs. | Junjiang Wu Mengyuan Gao Yubo Chai Pengke Liu Bo Zhang Junwei Liu Long Ye | 2021 | Materials Reports(Energy)2021，1，4： | 1 |
| 16 | An international Delphi consensus statement on metabolic dysfunction-associated fatty liver disease and risk of chronic kidney disease显示文摘Background:With the rising global prevalence of fatty liver disease related to metabolic dysfunction,the association of this common liver condition with chronic kidney disease(CKD)has become increasingly evident.In 2020,the more inclusive term metabolic dysfunction-associated fatty liver disease(MAFLD)was proposed to replace the term non-alcoholic fatty liver disease(NAFLD).The observed association between MAFLD and CKD and our understanding that CKD can be a consequence of underlying metabolic dysfunction support the notion that individuals with MAFLD are at higher risk of having and developing CKD compared with those without MAFLD.However,to date,there is no appropriate guidance on CKD in individuals with MAFLD.Furthermore,there has been little attention paid to the link between MAFLD and CKD in the Nephrology community.Methods and Results:Using a Delphi-based approach,a multidisciplinary panel of 50 international experts from 26 countries reached a consensus on some of the open research questions regarding the link between MAFLD and CKD.Conclusions:This Delphi-based consensus statement provided guidance on the epidemiology,mechanisms,management and treatment of MAFLD and CKD,as well as the relationship between the severity of MAFLD and risk of CKD,which establish a framework for the early prevention and management of these two common and interconnected diseases. | Dan-Qin Sun Giovanni Targher Christopher D.Byrne David C.Wheeler Vincent Wai-Sun Wong Jian-Gao Fan Herbert Tilg Wei-Jie Yuan Christoph Wanner Xin Gao Michelle T.Long Mehmet Kanbay Mindie H.Nguyen Sankar D.Navaneethan Yusuf Yilmaz Yuli Huang Rino A.Gani Pierluigi Marzuillo Jérôme Boursier Huijie Zhang Chan-Young Jung Jin Chai Luca Valenti George Papatheodoridis Giovanni Musso Yu-Jun Wong Mohamed El-Kassas Nahum Méndez-Sánchez Silvia Sookoian Michael Pavlides Ajay Duseja Adriaan G.Holleboom Junping Shi Wah-Kheong Chan Yasser Fouad Junwei Yang Sombat Treeprasertsuk Helena Cortez-Pinto Masahide Hamaguchi Manuel Romero-Gomez Mamun Al Mahtab Ponsiano Ocama Atsushi Nakajima Chunsun Dai Mohammed Eslam Lai Wei Jacob George Ming-Hua Zheng | 2023 | Hepatobiliary Surgery and Nutrition2023，12，3： | 1 |
| 17 | Functional diversity dominates positive species mixture effects on ecosystem multifunctionality in subtropical plantations显示文摘Mixed-species plantations generally exhibit higher ecosystem multifunctionality than monospecific plantations.However,it is unclear how tree species functional composition influences species mixture effects on ecosystem multifunctionality.We selected 171 monospecific and mixed-species plantations from nine regions across subtropical China,and quantified 13 key ecosystem functional properties to investigate how species mixture effects on ecosystem multifunctionality are modulated by functional diversity and identity.We found that ecosystem multifunctionality was significantly higher(p<0.05)in mixed tree plantations than in monospecific plantations except the mixed-conifer species plantations.Across all regions,ecosystem multifunctionality was significantly higher(p<0.05)in mixed conifer-broadleaf plantations than in monospecific plantations of the corresponding species,but not different between mixed and monospecific coniferous plantations.The magnitude of species mixture effects on ecosystem multifunctionality varied greatly with tree species compositions.Taking Cunninghamia lanceolata Lamb.as an example,the effects varied from a range of 2.0%–9.6%when mixed with a conifer species to 36%–87%when mixed with a broadleaf species.The functional diversity was the dominate driver shaping ecosystem multifunctionality,while functional identity,as expressed by community-weighted mean of specific leaf area,also had a positive effect on ecosystem multifunctionality through the increased below-ground nitrogen and phosphorus stocks regulated by specific leaf area of the mixing tree species.Our study highlights the important role of functional diversity in shaping ecosystem multifunctionality across region-wide environmental conditions.Mixed conifer-broadleaf tree plantations with distinct functional traits benefit the enhancement of ecosystem multifunctionality,and the magnitude of species mixture effects is modulated by the functional identity of tree species composition;those relationships deserve a special consideration in multifunctional management context of subtropical plantations. | Xi Li Hui Wang Junwei Luan Scott X.Chang Bing Gao Yi Wang Shirong Liu | 2022 | Forest Ecosystems2022，9，3： | 1 |
| 18 | Goose parvovirus structural proteins expressed by recombinant baculoviruses self-assemble into virus-like particles with strong immunogenicity in goose显示文摘 | Huanyu Ju Na Wei Qian Wang Chunyuan Wang Zhiqiang Jing Lu Guo Dapeng Liu Mingchun Gao Bo Ma Junwei Wang | 2011 | Biochemical and Biophysical Research Communications2011，，1： | 1 |
| 19 | The Application of PSO-LSSVM in Fault Diagnosis of Subway Auxiliary Inverter显示文摘 | Gao Junwei Yu Jinpeng Leng Ziwen | 2013 | ICICExpress Letters2013，4，3： | 1 |
| 20 | Traffic Flow Forecasting Based on Phase Space Reconstruction and PSO-LSSVM显示文摘 | GAO Junwei LENG Ziwen ZHANG Bin | 2014 | ICIC Express Letters2014，8，1： | 1 |
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