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| 1 | A step metallogenetic model for gold deposits in the northwestern Shandong Peninsula, China显示文摘Based on our study of the nature and variation of mineralization-controlling faults in their deep extension and the spatial distribution of gold orebodies in the northwestern Shandong Peninsula (NSP), here we propose that the gold deposits in the Jiaojia gold belt are controlled by listric faults and the gold deposits in the NSP are controlled by extensional fault system. We also suggest that there is a multiple mineralization space in the deep part of the NSP gold belt. As steps or benches occur along the deep extention of the listric fault where its dipping angle changes from steep to gentle, a number of gold deposits are correspondingly distributed as a steplike pattern, which is named as a step metallogenetic model for gold deposits in the NSP. The gold deposits in Shandong Peninsula were formed in the Cretaceous when the crust in the region experienced extention and thinning following the strong collision between North China Plate and Yangtze Plate during the Triassic. Crust anataxis, fluid remobilization, and extention-detachement of the crust are the leading factors for the gold mineralization. | SONG MingChun YI PiHou XU JunXiang CUI ShuXue SHEN Kun JIANG HongLi YUAN WenHua WANG HuaJiang | 2012 | Science China Earth Sciences2012，55，6： | 21 |
| 2 | COVID-19 Outbreak Caused by Contaminated Packaging of Imported Cold-Chain Products—Liaoning Province,China,July 2020显示文摘Summary What is known about this topic?Few major outbreaks of coronavirus disease 2019(COVID-19)have occurred in China after major nonpharmaceutical interventions and vaccines have been deployed and implemented.However,sporadic outbreaks that had high possibility to be linked to cold chain products were reported in several cities of China..What is added by this report?In July 2020,a COVID-19 outbreak occurred in Dalian,China.The investigations of this outbreak strongly suggested that the infection source was from COVID-19 virus-contaminated packaging of frozen seafood during inbound unloading personnel contact.What are the implications for public health practice?Virus contaminated paper surfaces could maintain infectivity for at least 17–24 days at-25℃.Exposure to COVID-19 virus-contaminated surfaces is a potential route for introducing the virus to a susceptible population.Countries with no domestic transmission of COVID-19 should consider introducing prevention strategies for both inbound travellers and imported goods.Several measures to prevent the introduction of the virus via cold-chain goods can be implemented. | Huilai Ma1 Jianqun Zhang Ji Wang Ying Qin Cao Chen Yang Song Liang Wang Jun Meng Lingling Mao Fengqin Li Ning Li Jian Cai Yong Zhang Dayan Wang Yunting Xia Hong Wang Shaofeng Jiang Xiang Zhao Peihua Niu Wenjie Tan Tao Ma Yecheng Yao Naiying Mao Zhen Zhu Tianjiao Ji Qian Yang Baoying Huang Li Zhao Jianxing Yu Li Bai Shuangli Zhu Dongyan Wang Yan Zhang Yingwei Sun Mingchun Luan Yanhai Wang Haibo Sun Shihong Yang Zhijian Bo Xiang Ren Zhongjie Li George Fu Gao Wei Yao Wenqing Yao Zijian Feng Wenbo Xu | 2021 | China CDC weekly2021，3，21： | 16 |
| 3 | Geophysical-Geological Interpretation and Deep-Seated Gold Deposit Prospecting in Sanshandong-Jiaojia Area, Eastern Shandong Province, China显示文摘Integrated gravitational, electrical-magnetic surveys and data processing carried out in the Sanshandao-Jiaojia area, Eastern Shandong Province, northeast China, aim to illuminate the geological characteristics of this shallow-covered area and delineate deep-seated gold prospecting targets. In this region, altogether 12 faults exert critical control on distribution of three types of Early Precambrian metamorphic rock series, i.e. those in the metamorphic rock area, in the granitic rock area underlying the metamorphic rock, and in the remnant metamorphic rock area in granites, respectively. Additionally, the faults have major effects on distribution of four Mesozoic Linglong rock bodies of granite, i.e. the Cangshang, Liangguo, Zhuqiao-Miaojia and Jincheng granites. The Sanshandao and Jiaojia Faults are two well-known regional ore-controlling faults; they have opposite dip direction, and intersect at a depth of 4500 m. Fracture alteration zones have striking geophysical differences relative to the surrounding county rocks. The two faults extend down along dip direction in a gentle wave form, and appear at some steps with different dips. These steps comprise favorable gold prospecting areas, consistent with a step metallogenic model. Six deep-seated gold-prospecting targets are delineated, i.e. Jincheng-Qianchenjia, Xiaoxizhuang-Zhaoxian, Xiyou-Wujiazhuangzi, Xiangyangling-Xinlicun, Panjiawuzi and Miaojia-Pinglidian. | SONG Mingchun WAN Guopu CAO Chunguo HE Chunyan | 2012 | Acta Geologica Sinica(English Edition)2012，86，3： | 15 |
| 4 | The Kiloton Class Jiaojia Gold Deposit in Eastern Shandong Province and Its Genesis显示文摘当以前建议了,在东方山东省的 Jiaojia 区域的最近的深勘探结果显示 Jiaojia 矿石域几单个金沉积物创作了实际上是极端大的金沉积物。这沉积物盖住 ∼40 km 2, 的一个区域并且由 Jiaojia 差错和它的第二等的差错显示出结构的控制。金 orebodies 通常沿着一样的矿化作用改变带,和主要 orebodies 发生与对方一起交叉或展出平行或重叠的分布。这沉积物的储备被估计是 1,黄金的 200t,是超过 1000t 黄金的第一金沉积物在中国保留。没有。在页岩深的 Sizhuang 矿石块的 I-1 orebody 使金储备保持比 350 t 大,否则 29% 总数保留列在后面由没有。我在有超过 150t 黄金的 Matang-Jiaojia 矿石块的 orebody 保留。这存款主要在 Jiaojia 差错的矿脉基卒下盘发生,并且在矿化作用,改变和结构介绍 zoned 模式。强烈使矿物化的地区强烈同意改变了并且构造地断裂了地区。这些 orebodies 显示象 strataform 一样, veinlike 或透镜的形状,并且通常显示出外面拧并且重现的特征,分叉并且收敛,膨胀并且缩小。orebodies 通常与剧降变化从沿着差错罢工变化的职务并且在轻轻的地点发生对陡峭轻轻。主要 orebodies 与控制矿石的差错的主要飞机平行,并且趋于从表面轻轻到深。orebodies 主要跳入到西南,与跳入 45 °-60° 的角度。控制矿石的差错的主要飞机附近的 Orebodies 比那些有更多的金资源离开主要差错地区。orebodies 的观点深度通常比沿着它的罢工方向的长度大;orebodies 变得厚,金等级从浅区域变得低到深区域。形成矿石的液体是 H 2O 公司 2-NaCl±CH4 类型与对低咸度中等温度、中等。硫同位素的价值(δ34 S 为金矿石的 CDT ) 在 11.08 ‰ 之间变化并且 12.58 ‰ ,显示混合了硫来源;氢同位素的价值(δD 从 -83.68‰ 的 V 降雪 ) 范围到 -116.95‰并且氧同位素的价值(δ18 O 在 12.04 ‰ 之间的 V 降雪 ) 范围并且 16.28 ‰ 。氢和氧同位素建议形成矿石的液体从主要岩浆发源,并且在迟了的阶段期间与大量大气的水混合。东方山东省金存款与让 mantle-crust-mixed 采购原料的 magmatic 活动被联系,并且也与热水的黄金扔的 orgenic 和 epithermal 分享一些类似。因为东方山东省黄金与与另外的金牌不同的唯一的 metallogenic 特征和形成背景扔,沉积物录入世界,我们把它称为 Jiaojia 类型金存款。千吨班 Jiaojia 金存款与液体活动,延期和分队有关源于岩浆的热 upwelling。在到在东方山东省的早白垩纪的迟了的舞台的中间的强壮的 magmatic 活动为金 depsoits 导致活跃液体,和提供的丰富的形成矿石的材料。而且,源于外壳的扩展的许多 extensional 结构为放的 orebody 提供了赞成空间。 | SONG Mingchun DENG Jun YI Pihou YANG Liqiang CUI Shuxue XU Junxiang ZHOU Mingling HUANG Tailing SONG Guozheng SONG Yingxin | 2014 | Acta Geologica Sinica(English Edition)2014，88，3： | 14 |
| 5 | Metallogenic Epoch of Nonferrous Metallic and Silver Deposits in the Jiaodong Peninsula, China and its Geological Significance显示文摘As China's most important gold-producing district,the Jiaodong Peninsula also contains copper,lead-zinc,molybdenum(tungsten),and other nonferrous metal ore deposits,but the space-time and genetic relationships with gold deposits remain uncertain.To investigate the temporal relationship between these nonferrous metal and gold ore deposits,We collected the samples from a number of nonferrous metallic and silver deposits and metallogenetic rock bodies in the eastern Jiaodong Peninsula for isotopic dating.The results show that the Re-Os isotopic model ages of the Lengjia molybdenum deposit in Rongcheng range from 114.5± 1.8 Ma to 112.6± 1.5 Ma,with an average age of 113.6± 1.6Ma;the LA-ICP-MS ^(206)Pb/^(238)U ages of 33 zircons in the sericitization porphyritic monzogranite that hosts the Tongjiazhuang silver deposit in Rongcheng range between 122 Ma and 109 Ma,with a weighted mean age of 116.04± 0.95 Ma;the LA-ICP-MS ^(206)Pb/^(238)U ages of 31 zircons in the copper metallogenic pyroxene monzodiorite that hosts the Kuangbei copper deposit in Rongcheng range from126 Ma to 106 Ma,with a weighted mean age of 116.6± 1.7 Ma;and the LA-ICP-MS ^(206)Pb/^(238)U ages of19 zircons in the pyroxene monzodiorite surrounding the Dadengge gold and multimetal deposit in Weihai range from 113 Ma to 110 Ma,with a weighted mean age of 111.7± 0.6 Ma.All these results indicate that the metallogenic ages of the silver and nonferrous metallic deposits in the Jiaodong Peninsula are in a limited range from 118 Ma to 111 Ma.Previous studies have demonstrated that the isotopic ages of gold deposits in the Jiaodong Peninsula range from 123 Ma to 110 Ma,while Weideshanian magmatism occurred between 126 Ma to 108 Ma.Both these ranges are grossly consistent with the metallogenic ages of silver and nonferrous metallic deposits in this study,suggesting that the large-scale mineralization occurred in the Early Cretaceous when magmatic activities were strong.This epoch may be linked to the lithosphere thinning and the thermo-upwelling extension in eastern China at that time.In addition,field investigation also shows that gold and nonferrous metallic deposits are distributed nearby the Weideshanian granite,with the nonferrous metallic deposits lying within or surrounding the granite pluton and the gold deposits outside the granite pluton.We propose the following mineralization scenario:In the Early Cretaceous,an intensive lithospheric extension induced partial melting and degassing of the metasomatized lithospheric mantle,which resulted in the formation of mantle-derived fluids enriched in metal elements.During the rapid process of magma ascent and intrusion,crust-derived fluids were activated by the magmatic thermal dome and served to further extract ore-forming materials from the crust.These fluids may have mixed with the mantle-derived fluid to form a crust-mantle mixing-type ore-forming fluid.The high-temperature conditions in the center or in contact with the granitic magmatic thermal dome would have been favorable for the formation of porphyry-type,skarn-type,and hydrothermal-vein-type ores,thus forming a series of Mo(W),Cu,and Pb-Zn deposits in the mid-eastern Jiaodong Peninsula.In contrast,the medium-to low-temperature conditions in the periphery of the magmatic thermal dome would have favored the deposition of gold(silver) ores under the appropriate physiochemical and structural conditions.The metallogenic epoch of the molybdenum,copper,and silver deposits,and their spatio-temporal and genetic relations to the gold deposits,as demonstrated in this study,not only provide important insights to the study of regional metallogeny,our understanding of the metallogenesis of the Jiaodong type gold deposit,and the geodynamic background of the large-scale mineralization in the Jiaodong Peninsula,but also have practical value in guiding the mineral exploration. | SONG Mingchun WANG Shanshan YANG Lixin LI Jie LI Shiyong DING Zhengjiang | 2017 | Acta Geologica Sinica(English Edition)2017，91，4： | 12 |
| 6 | Microstructure, biodegradation, antibacterial and mechanical properties of ZK60-Cu alloys prepared by selective laser melting technique显示文摘Magnesium(Mg) alloys are receiving increasing attention for body implants owing to their good biocompatibility and biodegradability. However, they often suffer from bacterial infections on account of their insufficient antibacterial ability. In this study, ZK60-x Cu(x = 0, 0.2, 0.4, 0.6 and 0.8 wt%) alloys were prepared by selective laser melting(SLM) with alloying copper(Cu) to enhance their antibacterial ability.Results showed that ZK60-Cu alloys exhibited strong antibacterial ability due to combination of release of Cu ions and alkaline environment which could kill bacteria by destroying cellular membrane structure,denaturing enzymes and inhibiting deoxyribonucleic acid(DNA) replication. In addition, their compressive strength increased due to grain refinement and uniformly dispersing of short-bar shaped MgZnCu phases. Moreover, ZK60-Cu alloys also exhibited good cytocompatibility. In summary, ZK60-Cu alloys with antibacterial ability may be promising implants for biomedical applications. | Cijun Shuai Long Liu Mingchun Zhao Pei Feng Youwen Yang Wang Guo Chengde Gao Fulai Yuan | 2018 | Journal of Materials Science & Technology2018，34，10： | 12 |
| 7 | MicroTom Metabolic Network: Rewiring Tomato Metabolic Regulatory Network throughout the Growth Cycle显示文摘Tomato(Solanum lycopersicum)is a major horticultural crop worldwide and has emerged as a preeminent model for metabolic research.Although many research efforts have focused on the analysis of metabolite differences between varieties and species,the dynamics of metabolic changes during the tomato growth cycle and the regulatory networks that underlie these changes are poorly understood.In this study,we integrated high-resolution spatio-temporal metabolome and transcriptome data to systematically explore the metabolic landscape across 20 major tomato tissues and growth stages.In the resulting MicroTom Metabolic Network,the 540 detected metabolites and their co-expressed genes could be divided into 10 distinct clusters based on their biological functions.Using this dataset,we constructed a global map of the major metabolic changes that occur throughout the tomato growth cycle and dissected the underlying regulatory network.In addition to verifying previously well-established regulatory networks for important metabolites,we identified novel transcription factors that regulate the biosynthesis of important secondary metabolites such as steroidal glycoalkaloids and flavonoids.Our findings provide insights into spatiotemporal changes in tomato metabolism and generate a valuable resource for the study of metabolic regulatory processes in model plants. | Yan Li Yang Chen Lu Zhou Shengjie You Heng Deng Ya Chen Saleh Alseekh Yong Yuan Rao Fu Zixin Zhang Dan Su Alisdair R.Fernie Mondher Bouzayen Tao Ma Mingchun Liu Yang Zhang | 2020 | Molecular Plant2020，13，8： | 10 |
| 8 | A load simulation method of piezoelectric actuator in FEM for smart structures显示文摘More and more piezoelectric materials and structures have been used for structure control in aviation and aerospace industry. More efficient and convenient computation method for large complex structure with piezoelectric actuation devices is required. A load simulation method of piezoelectric actuation is presented in this paper. By this method, the freedom degree of finite element simulation is significantly reduced, the difficulty in defining in-plane voltage for multi-layers piezoelectric composite is overcome and the transfer computation between material main direction and the element main direction is simplified. The concept of simulation load is comprehensible and suitable for engineers of structure strength in shape and vibration control, thereby is valuable for promoting the application of piezoelectric material and structures in practical aviation and aerospace fields. | LI Min CHEN WeiMin WANG MingChun JIA LiJie | 2009 | Science China(Technological Sciences)2009，52，9： | 7 |
| 9 | Human fused NKG2D-IL-15 protein controls xenografted human gastric cancer through the recruitment and activation of NK cells显示文摘Interleukin (IL )-15 在生来的杀手(NK ) 和 CD8+T 房间增长和功能起一个重要作用并且是比为肿瘤免疫疗法的 IL-2 更有效的。由附近的房间的 IL-15 的 trans 演讲比它的可溶的 IL-15 为 NK 房间激活是更有效的。在这研究,熔化蛋白质 dsNKG2D-IL-15,由经由一个连接器联合到人的 IL-15 的人的 NKG2D 的二相同的细胞外的域组成了,在 Escherichia coli 被设计。DsNKG2D-IL-15 能高效地与二个 NKG2D 领域和 trans 礼品 IL-15 把人的肿瘤房间的链相关的蛋白质 A (云母) 绑在主要 histocompatibility 建筑群一级到 NK 或 CD8+ T 房间。我们移植了人的胃的癌症(SGC-7901 ) 房间进裸体老鼠和有进 C57BL/6 老鼠的云母(B16BL6 云母) 的宫外的表示的老鼠黑瘤房间。然后,我们学习了反肿瘤效果在二个 xenografted 肿瘤模特儿由 dsNKG2D-IL-15 调停了。人的 dsNKG2D-IL-15 在压制胃的癌症生长比 IL-15 展出了更高的效率。外长的人的 dsNKG2D-IL-15 集中地在老鼠肿瘤纸巾被散布基于在 vivo 实时成像。房间渗入了进跟随外部血 mononuclear 房间的注射进忍受人的胃的癌症的裸体老鼠的肿瘤纸巾的人的 CD56+ 的频率被人的 dsNKG2D-IL-15 治疗显著地增加。人的 dsNKG2D-IL-15 也由激活和招募的老鼠 NK 和 CD8+ T 房间推迟了移植黑瘤(B16BL6 云母) 的生长。在 C57BL/6 老鼠的人的 dsNKG2D-IL-15 的反黑瘤效果主要被减少由在里面老鼠 NK 房间的 vivo 弄空。这些数据热点为肿瘤的人的 dsNKG2D-IL-15 的潜在的使用治疗。 | Yan Chen Bei Chen Ti Yang Weiming Xiao Li Qian Yanbing Ding Mingchun Ji Xiaoqun Ge Weijuan Gong | 2017 | Cellular & Molecular Immunology2017，14，3： | 6 |
| 10 | Establishment and Characterization of a Cell Based Artificial Antigen-Presenting Cell for Expansion and Activation of CD8^+ T Cells Ex Vivo显示文摘Artificial antigen-presenting cells are expected to stimulate the expansion and acquisition of optimal therapeutic features of T cells before infusion. Here CD32 that binds to a crystallizable fragment of IgG monoclonal antibody was genetically expressed on human K562 leukemia cells to provide a ligand for T-cell receptor. CD86 and 4-1BBL,which are ligands of co-stimulating receptors of CD28 and 4-1BB,respectively,were also expressed on K562 cells. Then we accomplished the artificial antigen-presenting cells by coupling K32/CD86/4-1BBL cell with OKT3 monoclonal antibody against CD3,named K32/CD86/4-1BBL/OKT3 cells. These artificial modified cells had the abilities of inducing CD8+ T cell activation,promoting CD8+ T cell proliferation,division,and long-term growth,inhibiting CD8+ T cell apoptosis,and enhancing CD8+ T cell secretion of IFN-γ and perforin. Furthermore,antigen-specific cytotoxic T lymphocytes could be retained in the culture stimulated with K32/CD86/4-1BBL/OKT3 cells at least within 28 days. This approach was robust,simple,reproducible and economical for expansion and activation of CD8+ T cells and may have important therapeutic implications for adoptive immunotherapy. | Weijuan Gong Mingchun Ji Zhengfeng Cao Liheng Wang Yayun Qian Maozhi Hu Li Qian Xingyuan Pan | 2008 | Cellular & Molecular Immunology2008，5，1： | 5 |
| 11 | Two Types of Granites in the Western Yangtze Block and Their Implications for Regional Tectonic Evolution: Constraints from Geochemistry and Isotopic Data显示文摘In the western Yangtze Block, widespread Mesoproterozoic to Neoproterozoic rocks are the key to understanding the Precambrian tectonic-magmatic evolution of the region. However, their petrogenesis and tectonic setting are still controversial. In this paper, zircon U-Pb ages, Sm-Nd isotopic and whole-rock geochemical data are reported from selected fresh samples in the southern Dechang county, southwestern China, in order to constrain their emplacement age and magma source, as well as their petrogenesis and tectonic setting. They are mainly composed of biotite monzogranite, monzonitic granite, biotite granodiorites, and quartz diorite. Two ages of 1055 ± 43 Ma and 837.6 ± 3.8 Ma were obtained through zircon U-Pb dating by LA-ICP-MS and LA-MC-ICP-MS, respectively. According to their major element compositions, the Grenville-age granites are peraluminous calc-alkaline series calcic S-type granite. In contrast, the mid-Neoproterozoic granites are metaluminous calc-alkaline series alkalic I-type granite. Furthermore, the S-type granites are enriched in LREEs relative to HREEs with(La/Yb)_N ratios of 3.85–18.56 and underwent major fractionation with strongly negative Eu anomalies(Eu/Eu~* = 0.38–0.66). In the MORB-normalized trace element variation diagram, all the samples are enriched in Ce and large ion lithophile elements such as Rb, Th, and K, and depleted in high field strength elements such as Nb, and Ti, with negative Sr and Ti anomalies. The I-type granites are enriched in LREEs with slight negative Eu anomalies(Eu/Eu~* = 0.83–0.93). They are characterized by the enrichment of highly incompatible elements(such as K, Rb, Ba, Th) and LREEs, relative to MORB. Neodymium isotopic data show that the S-type granites display ^(143)Nd/(^(144) Nd) values of 0.51241–0.51256, and have ε_(Nd)(t = 1055 Ma) values of(-3.29) to(-3.81). Calculated t_(DM) ages yield values from 1.87 to 1.91 Ga with the t_(DM).2 stg ages of 1.86 to 1.9 Ga. The I-type granites have ^(143)Nd/(^(144) Nd) ratios between 0.51192 and 0.51195, corresponding to initial ε_(Nd)(t = 837 Ma) values of 1.22 to 5.63. Calculated t_(DM) ages yield values from 1.0 to 1.38 Ga and the t_(DM).2 stg ages yield values from 0.99 to 1.06 Ga. The S-type granites are distinguished as syn-collision granite, whereas the I-type granites were formed as arc magmas according to the Rb-(Yb+Ta) and R_1-R_2 tectonic discrimination diagrams. To conclude, there are two types of spatially associated granite, the Mesoproterozoic S-type granite which were derived from remelting of upper crustal mudstone and/or clastics and resulted from the convergence of two continental plates, and the mid-Neoproterozoic I-type granite which formed in continental arc and resulted from mantle-derived magma mixed crust material, in the western Yangtze Block. Furthermore, we suggest that collision between the Yangtze and Cathaysia blocks occurred at about 1055 Ma, and caused the Stype granite. The I-type granite related to the subduction of oceanic lithosphere eastward underneath the Yangtze Block in the mid-Neoproterozoic. | MABI Awei YANG Zhengxi ZHANG Mingchun WEN Dengkui LI Yanlong LIU Xuyang | 2018 | Acta Geologica Sinica(English Edition)2018，92，1： | 4 |
| 12 | Microstructure evolution and texture tailoring of reduced graphene oxide reinforced Zn scaffold显示文摘Zinc(Zn)possesses desirable degradability and favorable biocompatibility,thus being recognized as a promising bone implant material.Nevertheless,the insufficient mechanical performance limits its further clinical application.In this study,reduced graphene oxide(RGO)was used as reinforcement in Zn scaffold fabricated via laser additive manufacturing.Results showed that the homogeneously dispersed RGO simultaneously enhanced the strength and ductility of Zn scaffold.On one hand,the enhanced strength was ascribed to(i)the grain refinement caused by the pinning effect of RGO,(ii)the efficient load shift due to the huge specific surface area of RGO and the favorable interface bonding between RGO and Zn matrix,and(iii)the Orowan strengthening by the homogeneously distributed RGO.On the other hand,the improved ductility was owing to the RGO-induced random orientation of grain with texture index reducing from 20.5 to 7.3,which activated more slip systems and provided more space to accommodate dislocation.Furthermore,the cell test confirmed that RGO promoted cell growth and differentiation.This study demonstrated the great potential of RGO in tailoring the mechanical performance and cell behavior of Zn scaffold for bone repair. | Youwen Yang Yun Cheng Shuping Peng Liang Xu Chongxian He Fangwei Qi Mingchun Zhao Cijun Shuai | 2021 | Bioactive Materials2021，6，5： | 4 |
| 13 | NONLINEAR DYNAMICS OF LATERAL MICRO-RESONATOR INCLUDING VISCOUS AIR DAMPING显示文摘The nonlinear dynamics of the lateral micro-resonator including the air damping effect is researched. The air damping force is varied periodically during the resonator oscillating, and the air damp coefficient can not be fixed as a constant. Therefore the linear dynamic analysis which used the constant air damping coefficient can not describe the actual dynamic characteristics of the mi-cro-resonator. The nonlinear dynamic model including the air damping force is established. On the base of Navier-Stokes equation and nonlinear dynamical equation, a coupled fluid-solid numerical simulation method is developed and demonstrates that damping force is a vital factor in micro-comb structures. Compared with existing experimental result, the nonlinear numerical value has quite good agreement with it. The differences of the amplitudes (peak) between the experimental data and the results by the linear model and the nonlinear model are 74.5% and 6% respectively. Nonlinear nu-merical value is more exact than linear value and the method can be applied in other mi-cro-electro-mechanical systeme (MEMS) structures to simulate the dynamic performance. | GAO Rong WANG Xiaojing WANG Min YU Maohua XIE Mingchun | 2007 | Chinese Journal of Mechanical Engineering2007，20，3： | 3 |
| 14 | Designing a high Si reduced activation ferritic/martensitic steel for nuclear power generation by using Calphad method显示文摘A high Si reduced activation ferritic/martensitic(RAFM) steel for nuclear structure application is successfully designed by using Calphad method. The main designed chemical composition is C 0.18–0.22%, Cr10.0–10.5%, W 1.0–1.5%, Si 1.0–1.3%, V+Ta 0.30–0.45%, and Fe in balance. High Si design brings excellent corrosion resistance, while low activation is advantageous in the nuclear waste processing. The experimental results indicate that the newly designed high Si RAFM steel had full martensitic structure and uniformly distributed fine second phase particles, and exhibited excellent mechanical properties and corrosion resistance. Compared to the P91 steel, this new RAFM steel designed by Calphad method is expected to be a promising candidate used in nuclear power generation, which also provides a new and effective approach to the development of RAFM steel for nuclear application. | Chao Liu Quanqiang Shi Wei Yan Chunguang Shen Ke Yang Yiyin Shan Mingchun Zhao | 2019 | Journal of Materials Science & Technology2019，35，3： | 3 |
| 15 | Comprehensive comparison on the chemical metabolites and taste evaluation of tea after roasting using untargeted and pseudotargeted metabolomics显示文摘Roasting is a common manufacture technology for processing various teas.It is not only used in decreasing the water content of finished tea,but also improving the flavor of teas.In the present study,the roasted and non-roasted teas were compared by liquid-chromatography mass spectrometry and sensory evaluation.The roasted tea tasted less bitter and astringent.The content of main galloylated and simple catechins,caffeine and theobromine in roasted were significantly lower than non-roasted teas.Targeted taste-compounds metabolomics revealed that(-)-epigallocatechin gallate,kaempferol-glucose-rhamnose-glucose and(-)-epicatechin gallate were main contributors tightly correlated to astringent intensity.Flavonol glycosides including kaempferol-glucose,quercetin-glucose,kaempferol-glucose-rhamnose-glucose,and quercetin-glucose-rhamnose-glucose in roasted teas were also significantly less than non-roasted teas.To study the chemical changes during roasting,tea with a strong astringency was roasted under 80,100,120,140,and 160°C.With the increase of roasting temperature,the bitter and astringent intensity of tea was gradually decreased,but the main astringent compounds including(-)-epigallocatechin,(-)-epigallocatechin gallate and kaempferol/quercetin glycosides were irregularly varied with temperature.The Pearson correlation coefficient analysis suggested procyanidin B2,coumaroylquinic acids and gallotannins were tightly correlated to the astringent and bitter perceptions,while N-ethyl-2-pyrrolidonesubstituted flavan-3-ols were negatively correlated. | Zongde Jiang Zisheng Han Mingchun Wen Chi-Tang Ho You Wu Yijun Wang Na Xu Zhongwen Xie Jinsong Zhang Liang Zhang Xiaochun Wan | 2022 | Food Science and Human Wellness2022，11，3： | 3 |
| 16 | Screening ofα-glucosidase inhibitors in large-leaf yellow tea by offline bioassay coupled with liquid chromatography tandem mass spectrometry显示文摘Larger-leaf yellow tea(LYT)is a characteristic type of Chinese tea produced in Huoshan County,Anhui Province,which is made by mature leaves with stems.According to recent report,LYT showed competitive effects in anti-hyperglycemia in comparison to other teas such as green or black tea.However,the bioactive compounds of LYT are still undiscovered so far.For this purpose,5 fractions of LYT were prepared by sequential extraction.The in vitro bioassay results indicated that the ethyl acetate fraction of LYT had the strongest inhibitory effects onα-glucosidase andα-amylase.Fluorescence-quenching analysis and proteinbinding test revealed that the compounds of ethyl acetate fraction could inhibitα-glucosidase andα-amylase activities through binding to enzymes or other mechanisms.All chromatographic peaks of high-performance liquid chromatography(HPLC)of ethyl acetate fraction were separated and collected.The purified compounds were identified by liquid chromatography-mass spectrometry(LC-MS),and subsequently screened by calculating their inhibition ratio onα-glucosidase at the real concentration in LYT infusion.The results showed that(-)-epigallocatechin gallate,(-)-gallocatechin gallate,caffeine,N-ethyl-2-pyrrolidone-substituted flavan-3-ols were effective inhibitors forα-glucosidase. | You Wu Zisheng Han Mingchun Wen Chi-Tang Ho Zongde Jiang Yijun Wang Na Xu Zhongwen Xie Jinsong Zhang Liang Zhang Xiaochun Wan | 2022 | Food Science and Human Wellness2022，11，3： | 3 |
| 17 | A novel gene encoding goose immunoglobulin λ light chain显示文摘 | Yongli Guo Mingchun Gao Junwei Wang | 2012 | Acta Biochimica et Biophysica Sinica2012，44，9： | 2 |
| 18 | Thompson's conjecture for alternating group of degree 22显示文摘 | Mingchun XU | 2013 | Frontiers of Mathematics in China2013，8，5： | 2 |
| 19 | Immobilized MHC class I chain-related protein A synergizes with IL-15 and soluble 4-1BB ligand to expand NK cells with high cytotoxicity ex vivo显示文摘Major histocompatibility complex(MHC)class I chain-related protein A(MICA),which is a ligand for human NKG2D,is expressed by a variety of epithelial tumor cells and promotes the activation of natural killer(NK),CD81 and cd-T cells.Although ectopic expression of MICA on tumor cells elicits anti-tumor responses,soluble MICA downregulates the activities of lymphocytes.In this study,we showed that recombinant,immobilized MICA(iMICA)molecules coated on plastic wells weakly promote peripheral NK cell activation,secretion of interferon(IFN)-c and degranulation without inducing apoptosis.In addition,iMICA synergized with IL-15 and soluble 4-1BB ligand(s4-1BBL)to expand NK cells 25-to 42-fold in a 13-day culture,whereas NK cells stimulated only with IL-15 and s4-1BBL expanded 10-to 16-fold.In contrast toNKcells expanded by IL-15 and s4-1BBL stimulation,NKcells expanded long term in the presence of iMICA exhibited increased cytotoxicity against leukemia cells.These results suggest that large numbers ofNKcells with high cytotoxicity can be generated by stimulation with IL-15 and s4-1BBL in the presence of iMICA and that these cells can be used for adoptive cancer immunotherapy. | Weijuan Gong Weiming Xiao Li Qian Chunxiang Gong Maozhi Hu Xianyuan Pan Mingchun Ji | 2010 | Cellular & Molecular Immunology2010，7，6： | 2 |
| 20 | Newly Discovered Fluvial-Lacustrine Sediments in the Western Yangtze Block and their Geological Significance for the Emeishan Large Igneous Province显示文摘Objective The Emeishan large igneous province(ELIP)in SW China is the only one large igneous province in China recognized by international geologists.Previous studies of ELIP over past two decades indicate that the ELIP age,duration,scale and generation mechanism are still controversial.Among those scientific topics。 | MABI Awei ZHANG Mingchun YANG Zhengxi LI Yanlong WEN Dengkui LIU Xuyang | 2017 | Acta Geologica Sinica(English Edition)2017，91，2： | 2 |
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