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| 1 | Exosomal PD-L1 harbors active defense function to suppress T cell killing of breast cancer cells and promote tumor growth显示文摘 | Yi Yang Chia-Wei Li Li-Chuan Chan Yongkun Wei Jung-Mao Hsu Weiya Xia Jong-Ho Cha Junwei Hou Jennifer L. Hsu Linlin Sun Mien-Chie Hung | 2018 | Cell Research2018，28，8： | 35 |
| 2 | Palmitoylation stabilizes PD-L1 to promote breast tumor growth显示文摘Dear Editor,PD-L1 is a well-known transmembrane protein, which is highly expressed on many types of cancer cells. By binding to its receptor PD-1 on T cells, PD-L1 significantly inhibits T cells activation and activity, and thus plays a pivotal role in driving the escape of tumor cells from immune surveillance.^1. | Yi Yang Jung-Mao Hsu Linlin Sun Li-Chuan Chan Chia-Wei Li Jennifer L. Hsu Yongkun Wei Weiya Xia Junwei Hou Yufan Qiu Mien-Chie Hung | 2019 | Cell Research2019，29，1： | 14 |
| 3 | Efficient spectral regulation in Ce:Lu_(3)(Al,Cr)_(5)O_(12) and Ce:Lu_(3)(Al,Cr)_(5)O_(12)/Ce:Y_(3)Al_(5)O_(12) transparent ceramics with high color rendering index for high-power white LEDs/LDs显示文摘Realizing a high color rendering index(CRI)in Ce:LuAG transparent ceramics(TCs)with desired thermal stability is essential to their applications in white LEDs/LDs as color converters.In this study,based on the scheme of configuring the red component by Cr^(3+) doping,an efficient spectral regulation was realized in Ce,Cr:LuAG TCs.A unilateral shift phenomenon could be observed in both photoluminescence(PL)and photoluminescence excitation(PLE)spectra of TCs.By constructing TC-based white LED/LD devices in a remote excitation mode,luminescence properties of Ce,Cr:LuAG TCs were systematically investigated.The CRI values of Ce:LuAG TC based white LEDs could be increased by a magnitude of 46.2%.Particularly,by combining the as fabricated Ce,Cr:LuAG TCs with a 0.5 at% Ce:YAG TC,surprising CRI values of 88 and 85.5 were obtained in TC based white LEDs and LDs,respectively.Therefore,Ce,Cr:LuAG TC is a highly promising color convertor for high-power white LEDs/LDs applied in general lighting and displaying. | Tianyuan ZHOU Chen HOU Le ZHANG Yuelong MA Jian KANG Tao LI Rui WANG Jin HUANG Junwei LI Haidong REN Zhenxiao FU Farida ASELIM Ming LI Hao CHEN | 2021 | Journal of Advanced Ceramics2021，10，5： | 7 |
| 4 | A new unconventional HLA-A2-restricted epitope from HBV core protein elicits antiviral cytotoxic T lymphocytes显示文摘细胞毒素的 T 房间(CTL ) 在肝炎 B 的控制起一个关键作用病毒(HBV ) 感染和病毒的清理。然而,大多数识别 CTL epitopes 从遗传型 A 和 D 的 HBV 被导出,并且很少在在亚洲更流行的遗传型 B 和 C 的病毒被定义。因为 HBV 核心蛋白质(HBc ) 是最保守、产生免疫性的部件,在这研究,我们使用了盖住 HBc 屏蔽并且识别特定的 CTL epitopes 的一个重叠 9-mer 肽水池。异乎寻常的 HLA-A2-restricted epitope HBc141149 被结晶化分析发现,在结构上描绘了。immunogenicity 和 anti-HBV 活动进一步在 HBV 和 HLA-A2 被决定转基因的老鼠。最后,我们证明在 HBc141149 epitope 的变化与病毒的参数被联系,在 HBV 的疾病前进感染了病人。我们的数据因此提供卓见进这异乎寻常的 epitope 绑定的结构特征给 MHC-I 分子,以及 epitope 特定的 CTL 活动在 HBV 安排 T 房间反应和有免疫力的避免感染的病人。 | Lu Sun Yu Zhang Bao Zhao Mengmeng Deng Jun Liu Xin Li Junwei Hou Mingming Gui Shuijun Zhang Xiaodong Li George F. Gao Songdong Meng | 2014 | Protein & Cell2014，5，4： | 7 |
| 5 | Surface modification of plasma nitriding on AlxCoCrFeNi high-entropy alloys显示文摘Plasma nitriding is successfully employed in treating AlxCoCrFeNi high-entropy alloys(HEAs)with finelydivided Al content(i.e.,x values in molar ratio,x=0.1-0.8)to develop wear-resistant structural materials.Nitridation greatly removes the Al from the matrix that completely deplete the Ni-Al enriched phase,forming nanoscaled nitrides(AIN and CrN)precipitations near the surface.Nitriding promotes the hardness of present alloys with values widely ranging from 276 HV to 722 HV.Interestingly,the higher content the Al,the smaller thickness the nitrides layer,but the higher hardness due to the increased amount of hard nitrides phases and volume fraction of BCC phase.Significantly,plasma nitriding considerably improves the wear re sistance of AlxCoCrFeNi HEAs by 4-18 times. | Jinxiong Hou Wenwen Song Liwei Lan Junwei Qiao | 2020 | Journal of Materials Science & Technology2020，47，13： | 3 |
| 6 | Effects of injection frequency on the rotor stall margin显示文摘The stall margin of compressor could be improved effectively by rotor tip injection,and the periodic injection is commonly used in the research.The purpose of this work is to investigate the influence of injection frequency on the rotor stall margin.An unsteady CFD code was employed to simulate the flow field of the rotor with injections of different frequencies.Comparing the stall margin of the rotor with injections of different frequencies,it is shown that there is an optimal injection frequency,around which the rotor stability enhancement is the largest.When the injection frequency is away form the optimal frequency,the improvement in stable flow range decreases correspondingly.For the rotor in this paper,the optimal frequency was 1.5 times the frequency of tip leakage vortex(for short,TLV) fluctuation.Time-averaged loading distribution at 98.5% span indicates that the loading of the rotor near the leading edge is decreased through injection with the optimal frequency,and therefore,the stall could be delayed. | ZHOU JunWei,HOU AnPing & ZHOU Sheng National Key Laboratory on Aero-Engines,Beijing University of Aeronautics and Astronautics,Beijing 100191,China | 2010 | Science China(Technological Sciences)2010，53，1： | 2 |
| 7 | Controlled synthesis of TiO2 mesoporous microspheres via chemical vapor deposition显示文摘 | Hou Junwei Yang Xiuchun Lv Xiaoyi | 2012 | Journal of Alloys and Compounds2012，511，： | 1 |
| 8 | Synthesis and characterization of high density and high aspect ratio Ag_2S nanoparticle nanowires from a paired cell method显示文摘Ag_2S nanoparticle nanowires were prepared in a porous anodic aluminum oxide template by a simple paired cell method,and were characterized by XRD,FESEM,HRTEM and EDS.The results showed that the as-prepared nanowires were composed of monoclinic Ag_2S nanoparticles.The nanowire diameters ranged from 165 to 270 nm,and Ag_2S nanoparticles were nearly spherical with diameters of 40 to 60 nm.The paired cell method is simple,low cost and easy to control for the fabrication of high density and high aspect ratio Ag_2S nanoparticle nanowires.A formation mechanism for the nanoparticle nanowires was suggested. | LI XiaoNing YANG XiuChun HAN ShanShan LU Wei HOU JunWei LIU Yan | 2011 | Chinese Science Bulletin2011，56，17： | 1 |
| 9 | Simultaneous Optimization of Efficiency,Stretchability,and Stability in All-Polymer Solar Cells via Aggregation Control显示文摘With the emergence of Y-series small molecule acceptors,polymerizing the small molecule acceptors with aromatic linker units has attracted significant research attention,which has greatly advanced the photovoltaic performance of all-polymer solar cells.Despite the rapid increase in efficiency,the unique characteristics(e.g.,mechanical stretchability and flexibility)of all-polymer systems were still not thoroughly explored.In this work,we demonstrate an effective approach to simultaneously improve device performance,stability,and mechanical robustness of all-polymer solar cells by properly suppressing the aggregation and crystallization behaviors of polymerized Y-series acceptors.Strikingly,when introducing 50 wt%PYF-IT(a fluorinated version of PY-IT)into the well-known PM6:PY-IT system,the all-polymer devices delivered an impressive photovoltaic efficiency of 16.6%,significantly higher than that of the control binary cell(15.0%).Compared with the two binary systems,the optimal ternary blend exhibits more efficient charge separation and balanced charge transport accompanying with less recombination.Moreover,a high-performance 1.0 cm^(2)large-area device of 15%efficiency was demonstrated for the optimized ternary all-polymer blend,which offered a desirable PCE of 14.5%on flexible substrates and improved mechanical flexibility after bending 1000 cycles.Notably,these are among the best results for 1.0 cm^(2)all-polymer OPVs thus far.This work also heralds a bright future of all-polymer systems for flexible wearable energy-harvesting applications. | Kaihu Xian Kangkang Zhou Mingfei Li Junwei Liu Yaowen Zhang Tao Zhang Yong Cui Wenchao Zhao Chunming Yang Jianhui Hou Yanhou Geng Long Ye | 2023 | Chinese Journal of Chemistry2023，41，2： | 1 |
| 10 | Synthesis of highly crystallized ternary CdxZn1-xS nanowires by chemical vapor deposition显示文摘 | Hou Junwei Song Bo Zhang Zhihua at al | | Submitted to Acta0，，： | 1 |
| 11 | Forecasting of Short-term Load based on LMD and BBO-RBF Model显示文摘Short-term load forecasting is a basis of power system dispatching and operation. In order to improve the short term power load precision, a novel approach for short-term load forecasting is presented based on local mean decomposition (LMD) and the radial basis function neural network method (RBFNN). Firstly, the decomposition of LMD method based on characteristics of load data then the decomposed data are respectively predicted by using the RBF network model and predicted by using the BBO-RBF network model. The simulation results show that the RBF network model optimized by using BBO algorithm is optimized in error performance index, and the prediction accuracy is higher and more effective. | HOU Luting GAO Junwei | 2019 | International Journal of Plant Engineering and Management2019，24，2： | 1 |
| 12 | In vitro crevice corrosion of biodegradable magnesium in different solutions显示文摘Magnesium(Mg)is a promising biomedical metal because of its biodegradability.The crevice between tissue and Mg implant can not be neglected in some implantation sites due to inducing crevice corrosion of Mg.In this paper,a new single mold was designed to build the in vitro experimental setup and four kinds of solutions,i.e.the deionized water(DW),the 0.9 wt.%sodium chloride solution(NaCl),the phosphate buffer saline(PBS)and the modified simulated body fluid(m-SBF)were used to explore necessary factors of crevice corrosion in Mg.It was observed that crevice corrosion in Mg sheets would occur in NaCl and PBS solution under 0.2,0.5 and 0.8 mm crevice thickness.And it was found that there were two necessary factors,i.e.chloride ion and crevice dimension,in crevice corrosion.For the high-purity Mg cannulated screws,crevice corrosion could occur inside tunnel when immersed in PBS. | Bowei Chen Hongliu Wu Ruibang Yi Wenhui Wang Haidong Xu Shaoxiang Zhang Hongzhou Peng Junwei Ma Haomiao Jiang Rui Zan Shuang Qiao Yu Sun Peng Hou Pei Han Jiahua Ni Xiaonong Zhang | 2020 | Journal of Materials Science & Technology2020，52，17： | 0 |
| 13 | Refining acceptor aggregation in nonfullerene organic solar cells to achieve high efficiency and superior thermal stability显示文摘With the rapid increase in photoelectric conversion efficiency of organic photovoltaics(OPVs),prolonging the operational lifetime of devices becomes one of the critical prerequisites for commercial applications.Guided by the theoretical calculations of molecular stacking and miscibility,we proposed an effective approach to simultaneously improve device performance and thermal stability of high-efficiency OPVs by refining the aggregation of Y-series acceptors.The key to this approach is deliberately designing an asymmetric Y-series acceptor,named Y6-CNO,which acts as a third component regulator to finely tune the degree of acceptor aggregation and crystallization in the benchmark PM6:Y6-BO system.Strikingly,a champion photovoltaic efficiency of 18.0%was achieved by introducing 15 wt%Y6-CNO into the PM6:Y6-BO system,significantly higher than the control binary cell(16.7%).Moreover,annealing at 100°C for over 1,200 h does not markedly affect the photovoltaic performance of the optimal ternary devices,maintaining above 95%of the initial performance and exhibiting an exceptionally high T_(80)lifetime of 9,000 h under continuous thermal annealing.By contrast,binary devices suffer from excessive crystallization of acceptors with long-term annealing.Additionally,mixing thermodynamics combined with morphological characterizations were employed to elucidate the microstructure-thermal stability relationships.The ternary OPVs consisting of symmetric and asymmetric homologous acceptors form better charge transport channels and can effectively suppress excessive aggregation of acceptors under long-term annealing.This work demonstrates the effectiveness of refining acceptor aggregation via molecular design for highly efficient and stable nonfullerene-based OPVs. | Kaihu Xian Shengnan Zhang Ye Xu Junwei Liu Kangkang Zhou Zhongxiang Peng Mingfei Li Wenchao Zhao Yu Chen Zhuping Fei Jianhui Hou Yanhou Geng Long Ye | 2023 | Science China Chemistry2023，66，1： | 0 |
| 14 | Nitrogen-doped carbon nanotubes by multistep pyrolysis process as a promising anode material for lithium ion hybrid capacitors显示文摘Lithium-ion hybrid capacitors(LIHCs) is a promising electrochemical energy storage devices which combines the advantages of lithium-ion batteries and capacitors.Herein,we developed a facile multistep pyrolysis method,prepared an amorphous structure and a high-level N-doping carbon nanotubes(NCNTs),and by removing the Co catalyst,opening the port of NCNTs,and using NCNTs as anode material.It is shows good performance due to the electrolyte ions enter into the electrode materials and facilitate the charge transfer.Furthermore,we employ the porous carbon material(APDC) as the cathode to couple with anodes of NCNTs,building a LIHCs,it shows a high energy density of 173 Wh/kg at 200 W/kg and still retains 53 Wh/kg at a high power density of 10 kW/kg within the voltage window of 0-4.0 V,as well as outstanding cyclic life keep 80% capacity after 5000 cycles.This work provides an opportunity for the preparation of NCNTs,that is as a promising high-performance anode for LIHCs. | Juan Yang Dan Xu Ruilin Hou Junwei Lang Zhaoli Wang Zhengping Dong Jiantai Ma | 2020 | Chinese Chemical Letters2020，31，9： | 0 |
| 15 | Car-Parinello molecular dynamics simulations of thionitroxide and S-nitrosothiol in the gas phase,methanol,and water——A theoretical study of S-nitrosylation显示文摘A dilemma about whether thionitroxide radical (RSNHO) or S-nitrosothiol (RSNO) is observed in protein S-nitrosylation has arisen recently. To illustrate the effect of chemical environment on these structures, this paper presents quantum mechanical molecular dynamics of thionitroxide, and cis-and trans-S-nitrosothiols in the gas phase, methanol, and water. By using Car-Parrinello molecular dynamics (CPMD), we have observed that there is free rotation about the S-N bond at 300 K in thionitroxide, but no such rotation is observed for S-nitrosothiol. The C-S-N-O torsion angle distribution in thionitroxide is s-ignificantly dependent upon the surrounding environment, leading to either gauche-, cis-, or trans-conformation. In the case of S-nitrosothiol the C-S-N-O plane is twisted slightly by 5°-15° in the cis-isomer, while the periplanar structure is well-retained in the trans-isomer. The calculated results are in agreement with the X-ray crystallographic data of small molecular RSNO species. Interestingly, for both compounds, the CPMD simulations show that solvation can cause a decrease in the S-N bond length. Moreover, the oxygen atom of thionitroxide is found to be a good hydrogen-bond acceptor, forming an oxyanion-hole-like hydrogen bonding network. | LIANG Juan CHENG ShangLi HOU JunWei XU ZhenHao ZHAO Yi-Lei | 2012 | Science China Chemistry2012，55，10： | 0 |
| 16 | 从Spectre Verilog到AMS Designer:移植与可用性改良显示文摘Virtuoso AMS Designer(AMSD)包含大量尖端功能,超越了SpectreVerilog等其他解决方案。尽管如此,很多客户仍然使用SpectreVerilog,因为从SpectreVerilog移植到AMSD存在很多障碍和易用性问题。本文将会讨论在PDK转化、设计调整和Verilog文本用法等中间会遇到的障碍以及解决方案。此外,本文还会讨论具体的性能改进以及可用性和可调试性的改进。AMSD流程中加入了新的网表分析器(OSS网表分析器),以及一种新的仿真器流程,使得这些解决方案成为可能。此外AMSD仿真器本身也有很多重大性能改进。本文的最后部分将会详细介绍简单易行的移植过程,并且将会对照SpectreVerilog讨论具体的性能改进。这种新的方法学让客户可以用最低的代价迅速移植到AMSD并享受其丰富的语言支持和功能,从而大大提高设计工程师的生产效率。根据本文中所提到的解决方案,SpectreVerilog移植到AMSD的过程可以从一个月缩短至不到一天。设计工程师的效率也因为可用性、可调试性和性能的提升而得到进一步提升。这些都将在本文中提到,并附带性能的对比。 | Indu Jain Tina Najibi Lei Song Junwei Hou Vijay Setia | 2007 | 中国集成电路2007，16，10： | 0 |
| 17 | Some geometric properties of successive difference substitutions显示文摘This paper provides a new,geometric perspective to study successive difference substitutions,and proves that the sequence of the successive difference substitution sets is not convergent.An interesting result that a given k-dimensional rational hyperplane can be transformed to a k-dimensional coordinate hyperplane of new variables by finite steps of successive difference substitutions is presented.Moreover,a sufficient condition for the sequence of the successive difference substitution sets of a form being not terminating is obtained.That is,a class of polynomials which cannot be proved to be positive semi-definite by the successive difference substitution method are obtained. | HOU XiaoRong XU Song SHAO JunWei | 2011 | Science China(Information Sciences)2011，54，4： | 0 |
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