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| 1 | Safety and efficacy of carbon dioxide insufflation during gastric endoscopic submucosal dissection显示文摘AIM: To compare the safety and efficacy of carbon dioxide(CO2) and air insufflation during gastric endoscopic submucosal dissection(ESD).METHODS: This study involved 116 patients who underwent gastric ESD between January and December 2009.After eliminating 29 patients who fit the exclusion criteria,87 patients,without known pulmonary dysfunction,were randomized into the CO2 insufflation(n = 36) or air insufflation(n = 51) groups.Standard ESD was performed with a CO2 regulation unit(constant rate of 1.4 L/min) used for patients undergoing CO2 insufflation.Patients received diazepam for conscious sedation and pentazocine for analgesia.Transcutaneous CO2 tension(Ptc CO2) was recorded 15 min before,during,and after ESD with insufflation.Ptc CO2,the correlation between Ptc CO2 and procedure time,and ESD-related complications were compared between the two groups.Arterial blood gases were analyzed after ESD in the first 30 patients(12 with CO2 and 18 with air insufflation) to assess the correlation between arterial blood CO2 partial pressure(Pa CO2) and Ptc CO2.RESULTS: There were no differences in respiratoryfunctions,median sedative doses,or median procedure times between the groups.Similarly,there was no significant difference in post-ESD blood gas parameters,including Pa CO2,between the CO2 and air groups(44.6 mm Hg vs 45 mm Hg).Both groups demonstrated median p H values of 7.36,and none of the patients exhibited acidemia.No significant differences were observed between the CO2 and air groups with respect to baseline Ptc CO2(39 mm Hg vs 40 mm Hg),peak Ptc CO2 during ESD(52 mm Hg vs 51 mm Hg),or median Ptc CO2 after ESD(50 mm Hg vs 50 mm Hg).There was a strong correlation between Pa CO2 and Ptc CO2(r = 0.66; P < 0.001).The incidence of Mallory-Weiss tears was significantly lower with CO2 insufflation than with air insufflation(0% vs 15.6%,P = 0.013).CO2 insufflation did not cause any adverse events,such as CO2 narcosis or gas embolisms.CONCLUSION: CO2 insufflation during gastric ESD results in similar blood gas levels as air insufflation,and also reduces the incidence of Mallory-Weiss tears. | Jun Takada Hiroshi Araki Fumito Onogi Takayuki Nakanishi Masaya Kubota Takashi Ibuka Masahito Shimizu Hisataka Moriwaki | 2015 | World Journal of Gastroenterology2015，21，26： | 6 |
| 2 | Diagnosis of the jejunoileal lymphoma by double-balloon endoscopy显示文摘AIM:To investigate the feasibility of double-balloon endoscopy(DBE) to detect jejunoileal lymphoma,compared with fluorodeoxyglucose positron emission tomography(FDG-PET).METHODS:Between March 2004 and January 2011,we histologically confirmed involvement of malignant lymphoma of the jejunoileum in 31 patients by DBE and biopsy.In 20 patients of them,we performed with FDGPET.We retrospectively reviewed the records of these 20 patients.Their median age was 64 years(range 50-81).In the 20 patients,the pathological diagnosis of underlying non-Hodgkin's lymphoma(NHL) comprised follicular lymphoma(FL,n = 12),diffuse large B cell lymphoma(DLBCL,n = 4),mantle cell lymphoma(MCL,n = 2),enteropathy associated T cell lymphoma(ETL,n = 1) and anaplastic large cell lymphoma(ALCL,n = 1).RESULTS:Ten cases showed accumulation by FDGPET(50%).FDG-PET was positive in 3 of 12 FL cases(25%) while in 7 of 8 non-FL cases(88%,P < 0.05).Intestinal FL showed a significantly lower rate of positive FDG-PET,in comparison with other types of lymphoma.Cases with endoscopically elevated lesions(n = 10) showed positive FDG-PET in 2(20%),but those with other type NHL did in 8 of 10(80%,P < 0.05).When the cases having elevated type was compared with those not having elevated type lesion,the number of cases that showed accumulation of FDG was significantly smaller in the former than in the latter.CONCLUSION:In a significant proportion,small intestinal involvement cannot be pointed out by FDG-PET.Especially,FL is difficult to evaluate by FDG-PET but essentially requires DBE. | Takashi Ibuka Hiroshi Araki Tomohiko Sugiyama Takayuki Nakanishi Fumito Onogi Masahito Shimizu Takeshi Hara Tsuyoshi Takami Hisashi Tsurumi Hisataka Moriwaki | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，3： | 4 |
| 3 | 堰塞坝溃决及防范显示文摘 | Takahisa Mizuyama Shigekiyo Tabata Toshio Mori Fumito Watanabe Kimio Inoue4 宋守度 | 2008 | 水利水电技术2008，39，7： | 3 |
| 4 | Clinical trial: rebamipide promotes gastric ulcer healing by proton pump inhibitor after endoscopic submucosal dissection—a randomized controlled study显示文摘 | Tomohiro Kato Hiroshi Araki Fumito Onogi Takashi Ibuka Akihiko Sugiyama Eiichi Tomita Masahito Nagaki Hisataka Moriwaki | 2010 | Journal of Gastroenterology2010，，3： | 2 |
| 5 | Current Status of Pylorus-Preserving Gastrectomy for the Treatment of Gastric Cancer: A Questionnaire Survey and Review of Literatures显示文摘 | Chikashi Shibata Fumito Saijo Masayuki Kakyo Makoto Kinouchi Naoki Tanaka Iwao Sasaki Takashi Aikou | 2012 | World Journal of Surgery2012，，4： | 2 |
| 6 | On the dynamics of nitrite, nitrate and other biomarkers of nitric oxide production in inflammatory bowel disease显示文摘 | Fumito Saijo Alexandra B. Milsom Nathan S. Bryan Selena M. Bauer Thorsten Vowinkel Marina Ivanovic Chris Andry D. Neil Granger Juan Rodriguez Martin Feelisch | 2009 | Nitric Oxide2009，，2： | 2 |
| 7 | Effects of Secondary Structure of Fillers on the Mechanical Properties of Silica Filled Rubher Systems 显示文摘 | Yatsuyanagi Fumito Suzuki Nozomu Ito Masayoshi | 2001 | Polymer2001，42，23： | 1 |
| 8 | The Modelling of AISAS Marketing Process显示文摘 | Fumito K | 2009 | Journal of System Dynamics2009，，： | 1 |
| 9 | Clinical trial: rebamipide promotes gastric ulcer healing by proton pump inhibitor after endoscopic submucosal dissection—a randomized controlled study显示文摘 | Tomohiro Kato Hiroshi Araki Fumito Onogi Takashi Ibuka Akihiko Sugiyama Eiichi Tomita Masahito Nagaki Hisataka Moriwaki | 2010 | Journal of Gastroenterology2010，，3： | 1 |
| 10 | Resection of Hilar Cholangiocarcinoma: Concomitant Liver Resection Decreases Hepatic Recurrence显示文摘 | Fumito Ito Rashmi Agni Robert J. Rettammel Mark J. Been Clifford S. Cho David M. Mahvi Layton F. Rikkers Sharon M. Weber | 2008 | Annals of Surgery2008，，2： | 1 |
| 11 | Transmural dispersion of repolarization and ventricular tachyarrhythmias显示文摘 | Norikazu Watanabe Youichi Kobayashi Kaoru Tanno Fumito Miyoshi Taku Asano Mitsuharu Kawamura Yoshino Mikami Tarou Adachi Syunsyou Ryu Akira Miyata Takashi Katagiri | 2004 | Journal of Electrocardiology2004，，3： | 1 |
| 12 | 5-Hydroxytryptamine induces transient Ca2+ influx through Ni2+-insensitive Ca2+channels in rat vascular smooth muscle cells显示文摘 | Masahiko H Fumito K Takashi E | 1999 | Euro J Pharmacol1999，380，： | 1 |
| 13 | Experi*mental investigation of rising gas bubble characteristicsfrom a vertical tube under CCFL condition显示文摘 | KUNIHITO Matsumura FUMITO Kaminaga | 2012 | Scienceand Technology of Nuclear Installations2012，，： | 1 |
| 14 | Myeobial enhancement of ergothioneine by sub- merged cultivation of edible mushroom mycelia and its application as an antioxidative compound显示文摘 | Pramvadee TepwongAnupam Girl Fumito SasakiRikuo Fukui Toshiaki Ohshima | 2012 | Food chemistry2012，131，1： | 1 |
| 15 | Thoracic CT findings of adult T-Cell leukemia or lymphoma显示文摘 | Fumito O Yumiko A Yoshiyuki K | 2004 | AJR2004，182，3： | 1 |
| 16 | Isolation and structure determination of algicidal compounds from Ulva fasciata 显示文摘 | Alamsjah M A Shotaro H Fumito I | 2005 | Biosci Biotenol Bioehem2005，69，11： | 1 |
| 17 | The role of H 2 S bioavailability in endothelial dysfunction显示文摘 | Rui Wang Csaba Szabo Fumito Ichinose Asif Ahmed Matthew Whiteman Andreas Papapetropoulos | 2015 | Trends in Pharmacological Sciences2015，，9： | 1 |
| 18 | Pulmonary vasoconstriction and hypertension in mice with targeted disruption of the endothelial nitric oxide synthase (NOS 3) gene显示文摘 | Wolfgang S Fumito I Paul L | 1997 | Circulation Research1997，81，1： | 1 |
| 19 | Hilar Cholangiocarcinoma: Current Management显示文摘 | Fumito Ito Clifford S. Cho Layton F. Rikkers Sharon M. Weber | 2009 | Annals of Surgery2009，，2： | 1 |
| 20 | The modeling of AISAS marketing process 显示文摘 | Fumito K | 2009 | Joumal of System DylIaBlies2009，，8： | 1 |
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