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| 1 | Autonomic Nervous Function in Vasovagal Syncope of Children and Adolescents显示文摘Syncope is defined as a transient loss of consciousness due to global cerebral hypoperfusion, accompanied by loss of muscle tone and failure to maintain an active position. Vasovagal syncope (VVS) is the most common presentation of syncope, and its diagnostic criteria include:(1) absence of any other evident etiology for syncope or presyncope,(2) positive response to head-up tilt test with evident vasovagal reaction (hypotension and/or bradycardia), and (3) no concomitant chronic or acute disease [1, 2]. The onset of VVS peaks initially in childhood and adolescence, and accounts for 60%–70% of all syncopal cases. Clinicians pay great attention to syncope among children and adolescents, due to its high prevalence and its impact on patients’ quality of life. Affected individuals often experience mental stress, economic burdens, and accidental bodily injuries related to syncope [2]. While the pathogenesis of VVS is not fully understood, autonomic nervous dysfunction has been identified as a contributing mechanism. The examination of autonomic nervous function can provide important information about patients with syncope. | Chunyan Tao Chaoshu Tang Selena Chen Hongfang Jin Junbao Du | 2019 | Neuroscience Bulletin2019，35，5： | 6 |
| 2 | Effects of Traditional Chinese Medicinal Plants on Antiinsulin Resistance Bioactivity of DXMS-Induced Insulin Resistant HepG2 Cells显示文摘Medicinal plants have a long history of use in China to treat diabetic symptoms.Ancient Chinese medical manuscripts and ethnobotanical surveys document plant remedies that continue to be actively used in China for the treatment of diabetic symptoms.Based on a systematic ancient Chinese medical manuscripts review in combination with ethnobotanical survey,16 medicinal plants for the traditional treatment of diabetic symptoms were identified for the evaluation of anti-insulin resistance bioactivity.The biological activity of 16 medicinal plants was tested on dexamethasone(DXMS)-induced insulin resistant HepG2 cells.The result shows that 11 of the 16 medicinal plants enhanced glucose uptake of DXMS-induced insulin resistant HepG2 cells,thereby demonstrating their ability to increase insulin sensitivity,other five medicinal plants including Astragalus membranaceus were found ineffective.The study shows that ancient Chinese medical manuscripts and ethnobotanical surveys on plants for the prevention and treatment of diabetic symptoms provide a promising knowledge base for drug discovery to mitigate the global diabetes epidemic. | Jun-Zeng Ma Li-Xin Yang Xiao-Ling Shen Ji-Huan Qin Li-Lan Deng Selena Ahmed Hong-Xi Xu Da-Yuan Xue Jiang-Xia Ye Gang Xu | 2014 | Natural Products and Bioprospecting2014，4，4： | 4 |
| 3 | Spreading Social Influence with both Positive and Negative Opinions in Online Networks显示文摘Social networks are important media for spreading information, ideas, and influence among individuals.Most existing research focuses on understanding the characteristics of social networks, investigating how information is spread through the 'word-of-mouth' effect of social networks, or exploring social influences among individuals and groups. However, most studies ignore negative influences among individuals and groups. Motivated by the goal of alleviating social problems, such as drinking, smoking, and gambling, and influence-spreading problems, such as promoting new products, we consider positive and negative influences, and propose a new optimization problem called the Minimum-sized Positive Influential Node Set(MPINS) selection problem to identify the minimum set of influential nodes such that every node in the network can be positively influenced by these selected nodes with no less than a threshold of ?. Our contributions are threefold. First, we prove that, under the independent cascade model considering positive and negative influences, MPINS is APX-hard. Subsequently, we present a greedy approximation algorithm to address the MPINS selection problem. Finally, to validate the proposed greedy algorithm, we conduct extensive simulations and experiments on random graphs and seven different realworld data sets that represent small-, medium-, and large-scale networks. | Jing (Selena) He Meng Han Shouling Ji Tianyu Du Zhao Li | 2019 | Big Data Mining and Analytics2019，2，2： | 4 |
| 4 | Hydrogen Sulfide Regulating Myocardial Structure and Function by Targeting Cardiomyocyte Autophagy显示文摘 | Qing-You Zhang Hong-Fang Jin Selena Chen Qing-Hua Chen Chao-Shu Tang Jun-Bao Du Ya-Qian Huang | 2018 | Chinese Medical Journal2018，，7： | 4 |
| 5 | The Current Acceptance,Accessibility and Recognition of Chinese and Ayurvedic Medicine in the United States in the Public,Governmental,and Industrial Sectors显示文摘为了在互补、其他的药,对流行的最近的研究,接受,可接近性,和互补、其他的治疗的识别的美国估计接受的当前的水平,被考察。几个符号在美国指向互补、其他的药的增加的接受;互补、其他的药的使用显著地正在增加,中国药和 Ayurveda 的许多方面正在变得主流,在美国的专业人员正在开始被准许,并且保险公司开始正在盖住一些互补、其他的治疗。对真接受的留下的挑战包括限制西方的 mindset,出版研究的缺席,一致生产过程的缺乏和优秀标准,并且掺杂的害怕。尽管这个领域仍然面对许多挑战,包括中国药和 Ayurvedic 药,其他、互补的药正在变得更多接受并且在美国可存取。 | Jongbae J.PARK Selena Beckman-Harned Gayoung Cho Duckhee Kim Hangon Kim | 2012 | Chinese Journal of Integrative Medicine2012，18，6： | 3 |
| 6 | Ethnobotany and diversity of medicinal plants used by the Buyi in eastern Yunnan, China显示文摘The Buyi are a socio-linguistic group in Yunnan Province of southwest China that have a long history of using medicinal plants as part of their indigenous medical system.Given the limited written documentation of the Buyi indigenous medical system,the objective of this paper is to document the medicinal plants of the Buyi and associated traditional knowledge and transmission.Field research was conducted in four villages in Lubuge Township of Luoping County in Yunnan Province using ethnobotanical methodologies including participatory observation,semi-structured interviews,key informant interviews,and focus group discussions to elicit information on medicinal plants.In total,120 informants(including 15 key informants who are healers)were interviewed.This study found that a total of 121 medicinal plant species belonging to 64 families are used by the Buyi including by local healers to treat different diseases.Among the medicinal plants recorded in this study,56 species(46%)have not previously been documented in the scientific literature as having medicinal value,highlighting the pressing need for ethnobotanical documentation in indigenous communities.The most frequently used medicinal part was the leaf(24.9%of documented plants),and the most common preparation method was decoction(62.8%of medicinal).Medicinal plants were mainly used to treat rheumatism(12.4%of plants),trauma and injuries(9.6%).The documented plants are also used for other non-medicinal purposes including food,fodder,fencing,and ornamental.In addition,35 of the medicinal plants are considered poisonous and are used by local Buyi healers for medicine.The traditional Buyi beliefs and practices associated with the documented medicinal plants likely contributes to their conservation in the environments and around Buyi communities.This study further highlights that ethnomedicinal knowledge of the Buyi is at risk of disappearing due to increased introduction and use of modern medicine in Buyi communities,livelihood changes,rapid modernization,and urbanization.Research,policy,and community programs are urgently needed to conserve the biocultural diversity associated with the Buyi medical system including ethnobotanical knowledge towards supporting both environmental and human wellbeing. | Yong Xiong Xueyi Sui Selena Ahmed Zhi Wang Chunlin Long | 2020 | Plant Diversity2020，42，6： | 3 |
| 7 | Detection of Hypermethylated Vimentin in Urine of Patients with Colorectal Cancer显示文摘 | Benjamin P. Song Surbhi Jain Selena Y. Lin Quan Chen Timothy M. Block Wei Song Dean E. Brenner Ying-Hsiu Su | 2012 | The Journal of Molecular Diagnostics2012，，2： | 2 |
| 8 | On the dynamics of nitrite, nitrate and other biomarkers of nitric oxide production in inflammatory bowel disease显示文摘 | Fumito Saijo Alexandra B. Milsom Nathan S. Bryan Selena M. Bauer Thorsten Vowinkel Marina Ivanovic Chris Andry D. Neil Granger Juan Rodriguez Martin Feelisch | 2009 | Nitric Oxide2009，，2： | 2 |
| 9 | Gut microbiota analysis and its significance in vasovagal syncope in children显示文摘Background: Vasovagal syncope (VVS) is common in children and greatly affect both physical and mental health. But the mechanisms have not been completely explained. This study was designed to analyze the gut microbiota in children with VVS and explore its clinical significance. Methods: Fecal samples from 20 VVS children and 20 matched controls were collected, and the microbiota were analyzed by 16S rRNA gene sequencing. The diversity and microbiota compositions of the VVS cases and controls were compared with the independent sample t test or Mann-Whitney U test. The correlation between the predominant bacteria and clinical symptoms was analyzed using Pearson or Spearman correlation test. Results: No significant differences in diversity were evident between VVS and controls (P > 0.05). At the family level, the relative abundance of Ruminococcaceae was significantly higher in VVS children than in controls (median [Q1, Q3]: 22.10% [16.89%, 27.36%] vs. 13.92% [10.31%, 20.18%], Z=-2.40, P < 0.05), and LEfSe analysis revealed Ruminococcaceae as a discriminative feature (linear discriminant analysis [LDA] score > 4, P < 0.05). The relative abundance of Ruminococcaceae in VVS patients was positively correlated with the frequency of syncope (r= 0.616, P < 0.01). In terms of its correlation with hemodynamics, we showed that relative abundance of Ruminococcaceae was negatively correlated with the systolic and diastolic pressure reduction at the positive response in head-up tilt test (HUTT;r= -0.489 and -0.448, all P < 0.05), but was positively correlated with the mean pressure drop and decline rate (r= 0.489 and 0.467, all P < 0.05) as well as diastolic pressure drop and decline rate at the HUTT positive response (r= 0.579 and 0.589, all P < 0.01) in VVS patients. Conclusion: Ruminococcaceae was the predominant gut bacteria and was associated with the clinical symptoms and hemodynamics of VVS, suggesting that gut microbiota might be involved in the development of VVS. | Wei Bai Selena Chen Chao-Shu Tang Jian-Guang Qi Qing-Hua Cui Ming XU Jun-Bao Du Hong-Fang Jin | 2019 | Chinese Medical Journal2019，，4： | 2 |
| 10 | Body mass index is a promising predictor of response to oral rehydration saline in children with vasovagal syncope显示文摘Background:Vasovagal syncope(VVS)greatly impairs quality of life.The therapeutic efficacy of oral rehydration saline(ORS)for unselected VVS patients is not satisfactory due to the diverse mechanisms of the disease.Body mass index(BMI)was demonstrated to reflect blood volume to a certain extent.Therefore,the present study explored the capability of BMI to predict the therapeutic response of children with VVS to ORS treatment.Methods:Seventy-four children with VVS who visited the Syncope Unit of Pediatrics at Peking University First Hospital from November 2010 to June 2019 receiving ORS treatment were enrolled for this retrospective case-control study.A comparison of demographic,clinical,and hemodynamic characteristics was performed between responders and non-responders.The correlation between baseline BMI and response time was analyzed.To determine the value of baseline BMI in predicting the therapeutic efficacy of ORS in children with VVS,a receiver operating characteristic curve analysis was performed.Results:Fifty-two children were identified as responders,and the remaining 22 children were identified as non-responders.The baseline BMI of the responders was much lower than that of the non-responders(16.4[15.5,17.8]kg/m2vs.20.7±3.6 kg/m2,P<0.001),and baseline BMI was positively correlated with response time in the head-up tilt test after adjusting for sex(r=0.256,95%confidence interval[CI]:0.067-0.439,P=0.029).The area under the receiver operating characteristic curve of baseline BMI was 0.818(95%CI:0.704-0.932,P<0.001),and an optimal cut-off value of 18.9 kg/m2 yielded a sensitivity of 83%and a specificity of 73%to predict the efficacy of ORS in VVS.Conclusion:Prior to treatment,baseline BMI is a promising predictor of response to ORS in children with VVS. | Chun-Yan Tao Selena Chen Xue-Ying Li Chao-Shu Tang Jun-Bao Du Hong-Fang Jin | 2021 | Chinese Medical Journal2021，，4： | 2 |
| 11 | Effects of water availability and pest pressures on tea (Camellia sinensis ) growth and functional quality 显示文摘 | Selena Ahmed Colin M Orians Timothy S Griffin | 2013 | AoB plants advance access2013，，： | 1 |
| 12 | Identification of gram negative bacteria using nanoscale silicon microcavities 显示文摘 | Selena C Scott R H Philippe M F | 2001 | Journal of the American Chemical Society2001，123，11： | 1 |
| 13 | Nanoscale silicon microcavities for biosensing显示文摘 | Selena C Yi L Lewis J R | 2001 | Materials Science and Engineering C2001，15，12： | 1 |
| 14 | Pu-erh tea tasting in Yunnan, China: Correlation of drinkers’ perceptions to phytochemistry显示文摘 | Selena Ahmed Uchenna Unachukwu John Richard Stepp Charles M. Peters Chunlin Long Edward Kennelly | 2010 | Journal of Ethnopharmacology2010，，1： | 1 |
| 15 | Influence of visual targets and landmarks on honey bee foraging and waggle dancing显示文摘Animals use diverse sensory stimuli to navigate their environment and to recognize rewarding food sources.Honey bees use visual atributes of the targeted food source,such as its color,shape,size,direction and distance from the hive,and the landmarks around it to navigate during foraging.They transmit the location information of the food source to other bees if it is highly rewarding.To investigate the relative importance of these attributes,we trained bees to feeders in two different experiments.In the first experiment,we asked whether bees prefer to land on(a)a similar feeder at a different distance on the same heading or on(b)a visually distinct feeder located at the exact same location.We found that,within a short foraging range,bees relied heavily on the color and the shape of the food source and to a lesser extent on its distance from the hive.In the second experiment,we asked if moving the main landmark or the feeder(visual target)influenced recruitment dancing for the feeder.We found that foragers took longer to land and danced fewer circuits when the location of the food source,or a major landmark associated with it,changed.These results demonstrate that prominent visual atributes of food sources and landmarks are evidently more reliable than distance information and that foraging bees heavily utilize these visual cues at the later stages of their journey. | Bahram Kheradmand Julian Cassano Selena Gray James C.Nieh | 2020 | Insect Science2020，27，2： | 1 |
| 16 | The effect of dextromethorphan in preventing cholecalciferol - induced poison shyness and sickness -induced anorexia in the laboratory Norway rat显示文摘 | Elaine M Gould Selena J Holmes | 2008 | Pest Manage- ment Science2008，64，： | 1 |
| 17 | Odour emission factors for assessment and prediction of Italian MSW landfills odour impact 显示文摘 | Selena S Laura C Paolo C | 2005 | Atmospheric Environment2005，39，： | 1 |
| 18 | 在线教育的漫漫成功路显示文摘近年来,大规模在线开放课程,也就是“慕课”,饱受瞩目和追捧,甚至被誉为传统教育的颠覆者和现代教育的未来。然而,这种旨在普及高等教育的新兴教育模式逐渐暴露出了课程完成率低,用户体验不佳,不够正规等问题。 | Selena Larson Cecilia Wei | 2014 | 新东方英语(中英文版)2014，，10： | 1 |
| 19 | Electronic noses for the continuous monitoring of odors from a wastewater treatment plant at specific receptors: Focus on training methods显示文摘 | Laura Capelli Selena Sironi Paolo Centola | 2008 | Sensors and Actuators B2008，131，1： | 1 |
| 20 | Inter- action between glutathione - S - transferase polymor- phisms, smoking habit, and HPV infection in cervical cancer risk 显示文摘 | Selena Palma Flavia Novelli Luca Padua | 2010 | Journal of Cancer Research and Clini- cal Oncology2010，7，： | 1 |
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