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| 1 | Safety and efficacy of carbon dioxide insufflation during gastric endoscopic submucosal dissection显示文摘AIM: To compare the safety and efficacy of carbon dioxide(CO2) and air insufflation during gastric endoscopic submucosal dissection(ESD).METHODS: This study involved 116 patients who underwent gastric ESD between January and December 2009.After eliminating 29 patients who fit the exclusion criteria,87 patients,without known pulmonary dysfunction,were randomized into the CO2 insufflation(n = 36) or air insufflation(n = 51) groups.Standard ESD was performed with a CO2 regulation unit(constant rate of 1.4 L/min) used for patients undergoing CO2 insufflation.Patients received diazepam for conscious sedation and pentazocine for analgesia.Transcutaneous CO2 tension(Ptc CO2) was recorded 15 min before,during,and after ESD with insufflation.Ptc CO2,the correlation between Ptc CO2 and procedure time,and ESD-related complications were compared between the two groups.Arterial blood gases were analyzed after ESD in the first 30 patients(12 with CO2 and 18 with air insufflation) to assess the correlation between arterial blood CO2 partial pressure(Pa CO2) and Ptc CO2.RESULTS: There were no differences in respiratoryfunctions,median sedative doses,or median procedure times between the groups.Similarly,there was no significant difference in post-ESD blood gas parameters,including Pa CO2,between the CO2 and air groups(44.6 mm Hg vs 45 mm Hg).Both groups demonstrated median p H values of 7.36,and none of the patients exhibited acidemia.No significant differences were observed between the CO2 and air groups with respect to baseline Ptc CO2(39 mm Hg vs 40 mm Hg),peak Ptc CO2 during ESD(52 mm Hg vs 51 mm Hg),or median Ptc CO2 after ESD(50 mm Hg vs 50 mm Hg).There was a strong correlation between Pa CO2 and Ptc CO2(r = 0.66; P < 0.001).The incidence of Mallory-Weiss tears was significantly lower with CO2 insufflation than with air insufflation(0% vs 15.6%,P = 0.013).CO2 insufflation did not cause any adverse events,such as CO2 narcosis or gas embolisms.CONCLUSION: CO2 insufflation during gastric ESD results in similar blood gas levels as air insufflation,and also reduces the incidence of Mallory-Weiss tears. | Jun Takada Hiroshi Araki Fumito Onogi Takayuki Nakanishi Masaya Kubota Takashi Ibuka Masahito Shimizu Hisataka Moriwaki | 2015 | World Journal of Gastroenterology2015，21，26： | 6 |
| 2 | Diagnosis of the jejunoileal lymphoma by double-balloon endoscopy显示文摘AIM:To investigate the feasibility of double-balloon endoscopy(DBE) to detect jejunoileal lymphoma,compared with fluorodeoxyglucose positron emission tomography(FDG-PET).METHODS:Between March 2004 and January 2011,we histologically confirmed involvement of malignant lymphoma of the jejunoileum in 31 patients by DBE and biopsy.In 20 patients of them,we performed with FDGPET.We retrospectively reviewed the records of these 20 patients.Their median age was 64 years(range 50-81).In the 20 patients,the pathological diagnosis of underlying non-Hodgkin's lymphoma(NHL) comprised follicular lymphoma(FL,n = 12),diffuse large B cell lymphoma(DLBCL,n = 4),mantle cell lymphoma(MCL,n = 2),enteropathy associated T cell lymphoma(ETL,n = 1) and anaplastic large cell lymphoma(ALCL,n = 1).RESULTS:Ten cases showed accumulation by FDGPET(50%).FDG-PET was positive in 3 of 12 FL cases(25%) while in 7 of 8 non-FL cases(88%,P < 0.05).Intestinal FL showed a significantly lower rate of positive FDG-PET,in comparison with other types of lymphoma.Cases with endoscopically elevated lesions(n = 10) showed positive FDG-PET in 2(20%),but those with other type NHL did in 8 of 10(80%,P < 0.05).When the cases having elevated type was compared with those not having elevated type lesion,the number of cases that showed accumulation of FDG was significantly smaller in the former than in the latter.CONCLUSION:In a significant proportion,small intestinal involvement cannot be pointed out by FDG-PET.Especially,FL is difficult to evaluate by FDG-PET but essentially requires DBE. | Takashi Ibuka Hiroshi Araki Tomohiko Sugiyama Takayuki Nakanishi Fumito Onogi Masahito Shimizu Takeshi Hara Tsuyoshi Takami Hisashi Tsurumi Hisataka Moriwaki | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，3： | 4 |
| 3 | Integration of Fault Analysis and Interlock Controller Synthesis for Batch Processes显示文摘在各种各样的决策之中的集成处理,例如计划,图案,和操作对动态、灵活的批生产必要。完成批生产集成,为各种各样的决策过程使用的普通模型的利用是一条有效途径。从这个观点,一个批系统由一张 Petri 网描述了的普通模型被建议。在这篇文章,为批进程的一种故障诊断技术用差错繁殖和差错分析的集成的可能性的信息被介绍,控制器合成根据 Petri 网络被讨论基于的普通模型。 | Susumu Hashizume Tomoyuki Yajima Yukiko Kuwashita Katsuaki Onogi | 2008 | Chinese Journal of Chemical Engineering2008，16，1： | 2 |
| 4 | Clinical trial: rebamipide promotes gastric ulcer healing by proton pump inhibitor after endoscopic submucosal dissection—a randomized controlled study显示文摘 | Tomohiro Kato Hiroshi Araki Fumito Onogi Takashi Ibuka Akihiko Sugiyama Eiichi Tomita Masahito Nagaki Hisataka Moriwaki | 2010 | Journal of Gastroenterology2010，，3： | 2 |
| 5 | Isoxazolidine-3,5-dione and noncyclic 1,3-dicarbonyl compounds as hypoglycemic agents显示文摘 | Syoji Onogi Masahiro Tanaka | 1998 | J Med Chem1998，41，11： | 1 |
| 6 | Photobleaching of the“Raman spectroscopic signature of life”and mitochondrial activity in rho-budding yeast cells显示文摘 | Onogi C Hamaguchi H O | 2009 | J Phys Chem B2009，113，10： | 1 |
| 7 | The JRA-2S reanalysis显示文摘 | Onogi Kazutoshi Tsutsui Junichi Koide Hiroshi | 2007 | J Meteor Soc Japan2007，85，3： | 1 |
| 8 | Clinical trial: rebamipide promotes gastric ulcer healing by proton pump inhibitor after endoscopic submucosal dissection—a randomized controlled study显示文摘 | Tomohiro Kato Hiroshi Araki Fumito Onogi Takashi Ibuka Akihiko Sugiyama Eiichi Tomita Masahito Nagaki Hisataka Moriwaki | 2010 | Journal of Gastroenterology2010，，3： | 1 |
| 9 | Rheological properties of polymer solutions and melts containing suspended particles 显示文摘 | ONOGI S MATSUMOTO T | 1981 | PolymEng Rev1981，，1： | 1 |
| 10 | The JRA-25 Reanalysis显示文摘 | ONOGI K TSUTSUI J KOIDE H | 2007 | J Meteorol Soc Jpn2007，85，3： | 1 |
| 11 | Bikunin suppresses ex-pression of proinflammatory cytokines induced by lipopolysac-charide in neutrophils 显示文摘 | Kanayama S? Yamada Y Onogi A | 2007 | I Endotoxin Res2007，13，6： | 1 |
| 12 | Clinical implication of medroxyprogesterone acetate against advanced ovarian carcinoma: a pilot study 显示文摘 | NIWA K ONOGI K WU Y | 2008 | Eur J Gynaecol Oncol2008，29，3： | 1 |
| 13 | The JRA-25 reanalysis显示文摘 | Onogi K Tsutsui J Koide H | 2007 | Journal of the Meteorological Society of Japan2007，85，： | 1 |
| 14 | Preventive effects of glycyrrhizin on estrogen-related endometrial carcinogenesis in mice显示文摘 | Niwa K Lian Z Onogi K | 2007 | Oncol Rep2007，17，3： | 1 |
| 15 | A surface geochemical evaluation of the K-V figerprint technique at the Minami-Aga oil field显示文摘 | Nakashima K Onogi R | 1990 | Journal Japanese Association Petroleum Technology1990，55，： | 1 |
| 16 | Novel SR-rich-related protein clasp specifically interacts with inactivated Clk4 and induces the exon EB inclusion of Clk显示文摘 | KATSU R ONOGI H WADA K | 2002 | J Biol Chem2002，277，44： | 1 |
| 17 | Isoxazolidine-3,5-dione and noncyclic 1,3-dicarbonyl compounds as hypoglycemic agents显示文摘 | Shinkai H Onogi S Tanaka M | 1998 | J Med Chem1998，41，11： | 1 |
| 18 | Involvement of endoplasmicreticulum (ER) stress in podocyte injury induced by excessive pro-tein accumulation显示文摘 | Inagi R Nangaku M Onogi H | 2005 | Kidney Int2005，68，6： | 1 |
| 19 | Multiple endothelial injury in epicardial coronary artery induces downstream mierovascular spasm as well as remodeling partly via thromboxane A2 显示文摘 | Saitonh S Onogi F Aikawa K | 2001 | J Am Coll Cardiol2001，37，1： | 1 |
| 20 | Isoazolidine-3,5-dione and noncyclic 1,3-dicabonyl compounds as hypoglycemic agents显示文摘 | Shinkai H Onogi S Tanaka M | 1998 | J Med Chem1998，41，： | 1 |
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