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| 1 | Grain size records reveal variability of the East Asian Winter Monsoon since the Middle Holocene in the Central Yellow Sea mud area,China显示文摘Three cores(ZY-1,ZY-2 and ZY-3) retrieved from the Central Yellow Sea mud(CYSM) were analyzed in sensitive grain size and AMS 14 C dating to reconstruct the history of the East Asian Winter Monsoon(EAWM) since the Middle Holocene in the study area.The results show that these data provide a continuous history of the EAWM over the past 7.2 ka and that the EAWM can be divided into three periods:strong and highly fluctuating during 7.2-4.2 ka BP;moderate and relatively stable during 4.2-1.8 ka BP;and weakened during 1.8-0 ka BP.Compared with the East Asian Summer Monsoon(EASM) recorded in the previous studies,the evolutionary history of the EAWM broadly follows the orbital-derived winter insolation with a similar long-term step-decreased trend as the EASM.At the centennial scale,however,the EAWM intensified events correlate well with the EASM weakened events and the North Atlantic climatic variations(Bond events 0 to 5) within the dating error,most likely forced by the reduction of solar irradiance through changes in the oceanic-atmospheric circulation patterns. | HU BangQi YANG ZuoSheng ZHAO MeiXun Yoshiki SAITO FAN DeJiang WANG LiBo | 2012 | Science China Earth Sciences2012，55，10： | 39 |
| 2 | Synthesis and properties of phosphorus-containing bio-based epoxy resin from itaconic acid显示文摘A phosphorus-containing bio-based epoxy resin(EADI)was synthesized from itaconic acid(IA)and 9,10-dihydro-9-oxa-10-phosphaphenanthrene 10-oxide(DOPO).As a matrix,its cured epoxy network with methyl hexahydrophthalic anhydride(MHHPA)as the curing agent showed comparable glass-transition temperature and mechanical properties to diglycidyl ether in a bisphenol A(DGEBA)system as well as good flame retardancy with UL94 V-0 grade during a vertical burning test.As a reactive flame retardant,its flame-resistant effect on DGEBA/MHHPA system as well as its influence on the curing behavior and the thermal and mechanical properties of the modified epoxy resin were investigated.Results showed that after the introduction of EADI,not only were the flame retardancy determined by vertical burning test,LOI measurement,and thermogravimetric analysis significantly improved,but also the curing reactivity,glass transition temperature(T g),initial degradation temperature for 5%weight loss(T d(5%)),and flexural modulus of the cured system improved as well.EADI has great potential to be used as a green flame retardant in epoxy resin systems. | MA SongQi LIU XiaoQing JIANG YanHua FAN LiBo FENG JianXiang ZHU Jin | 2014 | Science China Chemistry2014，57，3： | 33 |
| 3 | Sea surface temperature records of core ZY2 from the central mud area in the South Yellow Sea during last 6200 years and related effect of the Yellow Sea Warm Current显示文摘Sea surface temperature (SST) records in the South Yellow Sea during the last 6200 years are reconstructed by the unsaturation index of long-chain alkenones (K 37 U ') in sediment core ZY2 from the central mud area.The SST records varied between 14.1 and 16.5°C (15.6°C on average),with 3 phases:(1) A high SST phase at 6.2-5.9 cal ka BP;(2) A low and intensely fluctuating SST phase at 5.9-2.3 cal ka BP;and (3) A high and stable SST phase since 2.3 cal ka BP.Variation of the SST records is similar to intensity of the Kuroshio Current (KC),and corresponds well in time to global cold climate events.However,the amplitude of the SST response to cooling events was significantly different in different phases.The SST response to global cooling event was weak while the KC was strong;and the SST response was strong while the KC was weak.The difference in amplitude of the SST response is possibly caused by the modulation effect of the Yellow Sea Warm Current which acts as a shelf branch of the KC and a compensating current induced by the East Asia winter monsoon.The warm waters brought by the Yellow Sea Warm Current cushion the SST decrease induced by climate cooling,and both the Kuroshio and East Asian winter monsoon play important roles in the modulation mechanism.The SST records display a periodicity of 1482 years.The same period was found in the KC records,indicating that variation of the SST records in the central South Yellow Sea is strongly affected by KC intensity.The same period was also found in Greenland ice cores and North Atlantic and Arabian Sea sediment cores,showing a regional response of marine environmental variability in the East China Seas to that in the global oceans. | WANG LiBo YANG ZuoSheng ZHANG RongPing FAN DeJiang ZHAO MeiXun HU BangQi | 2011 | Chinese Science Bulletin2011，56，15： | 13 |
| 4 | First light of the 1.8-m solar telescope–CLST显示文摘Large-aperture solar telescopes play an important role in solar observations and research,and require high temporal and spatial resolution[1].To solve some fundamental problems such as the solar dynamo,coronal heating,and the triggering of major solar eruptions,the spatial resolution for solar-atmosphere observation should reach at least 0.1 arcsec[2]. | ChangHui Rao NaiTing Gu XueJun Rao Cheng Li LanQiang Zhang JinLong Huang Lin Kong Ming Zhang YunTao Cheng Yi Pu Hua Bao YouMing Guo YangYi Liu JinSheng Yang LiBo Zhong ChangJun Wang Kai Fang XiaoJun Zhang DongHong Chen Cheng Wang XinLong Fan ZhiWu Yan KeLe Chen XiYa Wei Lei Zhu Hong Liu YongJian Wan Hao Xian WenLi Ma | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，10： | 6 |
| 5 | Brief Introduction of TianHe Exascale Prototype System显示文摘Facing the challenges of the next generation exascale computing,National University of Defense Technology has developed a prototype system to explore opportunities,solutions,and limits toward the next generation Tianhe system.This paper briefly introduces the prototype system,which is deployed at the National Supercomputer Center in Tianjin and has a theoretical peak performance of 3.15 Pflops.A total of 512 compute nodes are found where each node has three proprietary CPUs called Matrix-2000+.The system memory is 98.3 TB,and the storage is 1.4 PB in total. | Ruibo Wang Kai Lu Juan Chen Wenzhe Zhang Jinwen Li Yuan Yuan Pingjing Lu Libo Huang Shengguo Li Xiaokang Fan | 2021 | Tsinghua Science and Technology2021，26，3： | 5 |
| 6 | EAST-Educational Adaptive-optics Solar Telescope显示文摘For the public having a better understanding of solar activities,the Educational Adaptive-optics Solar Telescope(EAST)was built in July 2021 and is located at the Shanghai Astronomy Museum.The EAST consists of a 65 cm aperture solar telescope with a 177-element adaptive optics system and two-channel high resolution imaging system at the Hαand TiO bands,in addition to three full disk solar telescopes at CaK,Hαand TiO bands equipped on the tube of the main telescope.In this paper,the configuration of the EAST is described.Its performance and on-sky observational results are presented.The EAST,to our knowledge,is the most advanced solar telescope for the popularization of science in the world.Due to its excellent performance,the data acquired by the EAST can also be used for research on solar physics and space weather prediction. | Changhui Rao Xuejun Rao Zhimao Du Hua Bao Cheng Li Jinlong Huang Youming Guo Libo Zhong Qing Lin Xin Ge Jinsheng Yang Xinlong Fan Yangyi Liu Dan Jia Xin Li Mei Li Ming Zhang Yuntao Cheng Jiahui Zhou Jiawen Yao Lanqiang Zhang Naiting Gu | 2022 | Research in Astronomy and Astrophysics2022，22，6： | 3 |
| 7 | The Evaluation of Eco-environmental Sensitivity in Ordos City显示文摘This paper aims to reveal the difference of eco-environmental sensitivity and its influencing factors in the study area through carrying out the eco-environmental sensitivity evaluation based on land ecological security for 8 counties of Ordos City. Using fragstats landscape pattern analysis,GIS space method and RS analysis,based on ground investigation,this paper uses information mining and data analysis to extract index data for every village in the study area,carry out comprehensive quantitative evaluation,and finally calculate the comprehensive scores of eco-environmental sensitivity of the areas. The paper concludes that the highly sensitive areas and extremely sensitive areas are mainly concentrated in the eastern region of the eastern hilly and gully region and southern region of the Mu Us Desert in Ordos. The main reasons include severe soil erosion in hilly and gully region and serious desertification in southern Mu Us Desert area. So it is necessary to strengthen ecological environment protection in local areas. | Yanhong XU Xijun YAO Libo LU Haijiao FAN | 2015 | Asian Agricultural Research2015，7，2： | 2 |
| 8 | Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection: a descriptive study显示文摘 | HaiYing Chen Hui Yuan Rongbao Gao Jinxiang Zhang Dayan Wang Ying Xiong GuoYin Fan Fan Yang Xiaodan Li Jianfang Zhou Shumei Zou Lei Yang Tao Chen Libo Dong Hong Bo Xiang Zhao Ye Zhang Yu Lan Tian Bai Jie Dong Qun Li ShiWen Wang YanPing Zhang Hui Li Tian Go | 2014 | The Lancet2014，，： | 1 |
| 9 | Ground-layer adaptive optics for the New Vacuum Solar Telescope:Instrument description and first results显示文摘Ground-layer adaptive optics(GLAO)has shown its potential for use in solar observation owing to its wide field-of-view(FOV)correction.A high-order GLAO system that consists of a multiple direction Shack-Hartmann wavefront sensor(WFS),a realtime controller with a multi-CPU processor,and a 151-element deformable mirror was developed for the 1-m New Vacuum Solar Telescope at Yunnan Observatories,Chinese Academy of Sciences.A hexagonal microlens with 9×8 subapertures is employed in the WFS.The detection FOV is 42′′×37′′,in which 9(3×3)guide regions are extracted for multiple direction wavefront sensing with a frame rate of up to 2200 Hz.To our knowledge,this is the first professional solar GLAO system used as a regularly operating instrument for scientific observations.Its installation and adjustment were performed in the summer of 2021.In this article,a detailed account of the GLAO system and its first light results and a comprehensive analysis of the performance of the GLAO system are provided.The results show that this system can effectively improve the imaging quality after compensating for the wavefront aberration due to ground-layer turbulence. | Lanqiang Zhang Hua Bao Xuejun Rao Youming Guo Libo Zhong Xian Ran Nanfei Yan Jinsheng Yang Cheng Wang Jiahui Zhou Ying Yang Yunyao Long Xinlong Fan Zhongyi Feng Donghong Chen Changhui Rao | 2023 | Science China(Physics,Mechanics & Astronomy)2023，66，6： | 1 |
| 10 | Hydrothermal synthesis and photoluminescent properties of ZnO nanorods显示文摘 | Libo Fan Hongwei Song Te Li Lixin Yu Zhongxin Liu Guohui Pan Yanqiang Lei Xue Bai Tie Wang Zhuhong Zheng Xianggui Kong | 2006 | Journal of Luminescence2006，，： | 1 |
| 11 | Apoptosis related protein 3, an ATRA-upregulated membrane protein arrests the cell cycle at G1/S phase by decreasing the expression of cyclin D1显示文摘 | Fang Yu Guodong Yang Zhongliang Zhao Lin Ji Yunxin Cao Liyuan Bai Fan Lu Haiyan Fu Bo Huang Hua Li Jie Zhang Libo Yao Zifan Lu | 2007 | Biochemical and Biophysical Research Communications2007，，4： | 1 |
| 12 | Traffic Distribution of Circular Sailing Routing in Dense Multihop Wireless Networks显示文摘Shortest path routing protocol intends to minimize the total delay between every pair of destination node and source node. However, it is also well-known that shortest path routing suffers from uneven distribution of traffic load, especially in dense wireless networks. Recently, several new routing protocols are proposed in order to balance traffic load among nodes in a network. One of them is Circular Sailing Routing (CSR) which maps nodes on the surface of a sphere and select routes based on surface distances. CSR has been demonstrated with better load balance than shortest path routing via simulations. However, it is still open that what load distribution CSR can achieve. Therefore, in this paper, we theoretically analyze the traffic load distribution of CSR in a dense circular wireless network. Using the techniques developed by Hytti and Virtamo, we are able to derive the traffic load of any point inside the network. We then conduct extensive simulations to verify our theoretical results with grid and random networks. | Fan Li Xiao He Siyuan Chen Libo Jiang Yu Wang | 2013 | Tsinghua Science and Technology2013，18，3： | 0 |
| 13 | U.S.-Japanese TPP Strategies and China's Response显示文摘The U.S.-driven TPP has caught the attention of the region and is bringing uncertainty to East Asian economic integration.China,the U.S.and Japan have taken different positions on the TPP itself.The U.S.is actively participating in TPP negotiations and trying to dominate it.Japan regards the TPP as a tool with which it can further explore markets as well as strengthen its relationship with the U.S..China is currently assessing the U.S.shift in economic strategy towards East Asia and the potential impacts of TPP expansion. | Fan Libo Zheng Wei Zheng Xuedang Xing Haibing | 2013 | Contemporary International Relations2013，23，2： | 0 |
| 14 | Protein phosphatase 6 (Pp6) is crucial for regulatory T cell function and stability in autoimmunity显示文摘Regulatory T(T_(reg))cells constitute a dynamic population that is critical in autoimmunity.T_(reg) cell therapies for autoimmune diseases are mainly focused on enhancing their suppressive activities.However,recent studies demonstrated that certain inflammatory conditions induce T_(reg) cell instability with diminished FoxP3 expression and convert them into pathogenic effector cells.Therefore,the identification of novel targets crucial to both T_(reg) cell function and plasticity is of vital importance to the development of therapeutic approaches in autoimmunity.In this study,we found that conditional Pp6 knockout(cKO)in T_(reg) cells led to spontaneous autoinflammation,immune cell activation,and diminished levels of FoxP3 in CD4^(+)T cells in mice.Loss of Pp6 in T_(reg) cells exacerbated two classical mouse models of T_(reg)-related autoinflammation.Mechanistically,Pp6 deficiency increased CpG motif methylation of the FoxP3 locus by dephosphorylating Dnmt1 and enhancing Akt phosphorylation at Ser473/Thr308,leading to impaired FoxP3 expression in T_(reg) cells.In summary,our study proposes Pp6 as a critical positive regulator of FoxP3 that acts by decreasing DNA methylation of the FoxP3 gene enhancer and inhibiting Akt signaling,thus maintaining T_(reg) cell stability and preventing autoimmune diseases. | Wei Cai Junxun Zhang Hong Zhou Xiangxiao Li Fangzhou Lou Yang Sun Zhenyao Xu Jing Bai Qianqian Yin Zhikai Wang Libo Sun Xiaojie Cai Sibei Tang Yue Wu Li Fan Hong Wang Honglin Wang Qun Li | 2022 | Genes & Diseases2022，9，2： | 0 |
| 15 | Advances in high-performance MEMS pressure sensors:design,fabrication,and packaging显示文摘Pressure sensors play a vital role in aerospace,automotive,medical,and consumer electronics.Although microelectromechanical system(MEMS)-based pressure sensors have been widely used for decades,new trends in pressure sensors,including higher sensitivity,higher accuracy,better multifunctionality,smaller chip size,and smaller package size,have recently emerged.The demand for performance upgradation has led to breakthroughs in sensor materials,design,fabrication,and packaging methods,which have emerged frequently in recent decades.This paper reviews common new trends in MEMS pressure sensors,including minute differential pressure sensors(MDPSs),resonant pressure sensors(RPSs),integrated pressure sensors,miniaturized pressure chips,and leadless pressure sensors.To realize an extremely sensitive MDPS with broad application potential,including in medical ventilators and fire residual pressure monitors,the“beam-membrane-island”sensor design exhibits the best performance of 66μV/V/kPa with a natural frequency of 11.3 kHz.In high-accuracy applications,silicon and quartz RPS are analyzed,and both materials show±0.01%FS accuracy with respect to varying temperature coefficient of frequency(TCF)control methods.To improve MEMS sensor integration,different integrated“pressure+x”sensor designs and fabrication methods are compared.In this realm,the intercoupling effect still requires further investigation.Typical fabrication methods for microsized pressure sensor chips are also reviewed.To date,the chip thickness size can be controlled to be<0.1 mm,which is advantageous for implant sensors.Furthermore,a leadless pressure sensor was analyzed,offering an extremely small package size and harsh environmental compatibility.This review is structured as follows.The background of pressure sensors is first presented.Then,an in-depth introduction to MEMS pressure sensors based on different application scenarios is provided.Additionally,their respective characteristics and significant advancements are analyzed and summarized.Finally,development trends of MEMS pressure sensors in different fields are analyzed. | Xiangguang Han Mimi Huang Zutang Wu Yi Gao Yong Xia Ping Yang Shu Fan Xuhao Lu Xiaokai Yang Lin Liang Wenbi Su Lu Wang Zeyu Cui Yihe Zhao Zhikang Li Libo Zhao Zhuangde Jiang | 2023 | Microsystems & Nanoengineering2023，9，6： | 0 |
| 16 | Effects of Simvastatin on Endoplasmic Reticulum Stress-Mediated Apoptosis in Atherosclerotic Calcification显示文摘Objective:The effectiveness of statins in reducing atherosclerotic calcification remains controversial.The aim of this study was to confirm that simvastatin reduces atherosclerotic calcification and stabilizes plaque by restricting endoplasmic reticulum stress(ERS)-mediated apoptosis.Methods:Twenty-four 8-week-old male apolipoprotein E(ApoE)-/-mice(C57BL/6J genetic background)were selected and randomly divided into model(n=12)and simvastatin(n=12)groups.Twelve male C57BL/6J mice were selected as control group(n=12).The mice were adaptively fed for 2 weeks and were put on a high-fat diet thereafter.After 9 weeks,they were treated with simvastatin(20 mg/kg)or phosphate-buffered saline daily for 8 weeks.Aortic sinus samples were obtained from ApoE-/-and C57BL/6J mice for hematoxylin and eosin,von Kossa,alizarin Red S,terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling,and immunohistochemical staining after in vivo treatment with simvastatin.In addition,mouse vascular smooth muscle cells were analyzed after exposure to simvastatin in vitro.Results:Administration of simvastatin in vivo drastically attenuated the atherosclerosis,calcification,and apoptosis,and decreased the serum levels of triglycerides,total cholesterol,low-density lipoprotein cholesterol,and high-density lipoprotein cholesterol.The expression levels of glucose-regulated protein,78 kDa(GRP78),C/EBP homologous protein(CHOP),and caspase 12(CASP12)in the aortic sinus decreased in the simvastatin group compared with the model group.In vitro,simvastatin or simvastatin plus ERS inhibitor(taurine)attenuated calcification and apoptosis,and reduced the expression of ERS-related proteins GRP78,CHOP,and CASP12.Conclusion:Treatment with simvastatin suppressed atherosclerotic calcification.This effect may be mediated through the inhibition of ERS-related apoptosis. | Jianhua Li Libo Zhao Zhe Zhou Lin Liu Xiao Zou Weihao Xu Li Fan Muyang Yan Shengqi Wang | 2022 | Cardiology Discovery2022，2，4： | 0 |
| 17 | Visual object tracking:Progress,challenge,and future显示文摘Visual object tracking aims to continuously localize the target object of interest in a video sequence.As one of the most fundamental problems in computer vision,visual object tracking has a long list of critical applications including video surveillance,autonomous driving,human-machine interaction,augmented reality,robotics,etc.,in which the tracking system provides the capacity to report target positions in real time for subsequent visual analysis.In the past decades,visual object tracking has been extensively explored and has witnessed considerable progress,especially in deep-learning-based tracking. | Libo Zhang Heng Fan | 2023 | The Innovation2023，4，2： | 0 |
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