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197篇 您的检索式:作者名="Ela"
    题名 作者 年代 出处 被引量
1腔镜微创食管癌切除术的学习过程分析显示文摘目的总结腔镜微创食管癌切除术(MIE)的学习过程。方法选取同一组医生连续完成的MIE手术100例,按手术时间顺序分为3组:第1、2组各25例行胸腔镜并常规开腹手术,第3组50例行胸腹腔镜手术.分别记录手术时间、出血量、正常结构保护及并发症发生情况、术后ICU观察时间、住院时间、术后肿瘤病理及淋巴结清扫情况等临床资料,比较各组之间的差异。结果全组中96例患者顺利完成MIE,4例患者中转开胸,无中转开腹。中位手术时间310min,中位失血量200ml,中位清扫淋巴结22枚,总体并发症发生率50%。第1组与第2组比较,在保留奇静脉弓(P=0.010)、保留支气管动静脉(P=0.038)及左侧喉返神经胸段术中暴露率(P=0.048)方面的差异有统计学意义。前50例与后50例比较,在胸部手术时间(P=0.000)、失血量(P=0.025)、保留奇静脉弓(P=0.001)、保留支气管动静脉(P=0.000)、胸野淋巴结清扫(P=0.022)、左喉返神经链淋巴结清扫(P=0.000)及该神经起始部术中暴露率(P=0.002)方面的差异有统计学意义。结论MIE学习过程较长.应循序渐进。随着经验的积累和手术技巧的提升.MIE将逐渐显示其独特的优势并替代传统开胸食管癌切除术。谢绚 傅剑华 王军业 张旭 罗孔嘉 杨富 Amos Ela Bella 李小海 2012中华胃肠外科杂志2012,15,9:15
2新型可回收全覆膜镍钛合金支架治疗难治性食管良性狭窄显示文摘目的探讨自行设计的新型可回收抗反流全覆膜镍钛合金支架治疗难治性食管良性狭窄的疗效。方法2009年11月至2011年5月间中山大学肿瘤防治中心胸科采用新型支架治疗难治性食管良性狭窄患者8例。在支架置入术后第1、7、30和60天以及拔除支架术后1、2、3和6个月,进行胃镜和食管吞钡检查,评价患者吞咽功能改善及并发症发生情况。结果8例患者均成功置入新型支架.术后吞咽功能较术前明显改善(P〈0.05)。经9个月的中位随访,已拔除支架6例,其吞咽功能亦较术前明显改善(P〈0.05):支架继续留置2例,其中1例支架置入术后已15个月,目前仍进普通饮食:另1例支架置入术后2个月吞咽功能较术前改善.但3个月后吞咽功能减退至术前水平。8例患者远期吞咽功能改善率为7/8。术后再狭窄1例:支架脱落2例:肉芽过度增生3例,其中支架覆膜破裂致肉芽向内生长2例。结论新型可回收全覆膜镍钛合金支架置入食管良性狭窄术后和拔除支架后吞咽功能明显改善.远期再狭窄发生率低:但支架脱落发生率仍较高.支架覆膜材料易破裂.仍需进一步改进。李小海 胡祎 杨弘 Amos Ela Bella 傅剑华 2011中华胃肠外科杂志2011,14,11:7
3DESIS国际网络:可持续和社会创新的设计显示文摘2010年9月7-10日,Cumulus国际设计院校联盟大会将在上海召开,它在与DESIS国际联盟合作的基础上,将'可持续与社会创新设计'作为会议分主题之一。9月10日,DESIS国际论坛和DESIS-国际联盟会议将在世博会联合国馆举行。9月12日,DESIS国际研讨会'为地方发展的社会创新设计'将在江南大学设计学院举办。9月13-18日,意大利米兰理工大学与江南大学再次联手合作组织主题为'新农村、新城市、新生活'的食品网络设计工作坊。在九月份连续几个以'可持续与社会创新设计'为主题的国际论坛及工作坊即将开展的背景下,本刊编辑部约请了参会的Cumulus国际设计院校联盟以及DESIS国际联盟内的若干重量级嘉宾,为本刊第四期'可持续与社会创新设计'专题提供论文。本专题共8篇文章,分别从DESIS国际网络介绍,以及DESIS组织在中国、法国、中东、巴西等地区推广'可持续与社会创新设计'的具体项目出发,将'可持续与社会创新设计'从理论呼吁走向了设计实践探索,对中国当代可持续与社会创新设计的发展极具启发意义。Ezio Manzini Lara Penin Carla Cipolla Mugendi K.M'Rithaa Andrea Mendoza Francois Jegou Adital Ela 张桢 2010创意与设计2010,,4:7
4Maximum standardized uptake value on PET/CT in preoperative assessment of lymph node metastasis from thoracic esophageal squamous cell carcinoma显示文摘The presence of lymph node metastasis is an important prognostic factor for patients with esophageal cancer.Accurate assessment of lymph nodes in thoracic esophageal carcinoma is essential for selecting appropriate treatment and forecasting disease progression.Positron emission tomography combined with computed tomography(PET/CT)is becoming an important tool in the workup of esophageal carcinoma.Here,we evaluated the effectiveness of the maximum standardized uptake value(SUVmax)in assessing lymph node metastasis in esophageal squamous cell carcinoma(ESCC)prior to surgery.Fifty-nine surgical patients with pathologically confirmed thoracic ESCC were retrospectively studied.These patients underwent radical esophagectomy with pathologic evaluation of lymph nodes.They all had18F-FDG PET/CT scans in their preoperative staging procedures.None had a prior history of cancer.The pathologic status and PET/CT SUVmax of lymph nodes were collected to calculate the receiver operating characteristic(ROC)curve and to determine the best cutoff value of the PET/CT SUVmax to distinguish benign from malignant lymph nodes.Lymph node data from 27 others were used for the validation.A total of 323 lymph nodes including 39 metastatic lymph nodes were evaluated in the training cohort,and 117lymph nodes including 32 metastatic lymph nodes were evaluated in the validation cohort.The cutoff point of the SUVmax for lymph nodes was 4.1,as calculated by ROC curve(sensitivity,80%;specificity,92%;accuracy,90%).When this cutoff value was applied to the validation cohort,a sensitivity,a specificity,and an accuracy of 81%,88%,and 86%,respectively,were obtained.These results suggest that the SUVmax of lymph nodes predicts malignancy.Indeed,when an SUVmax of 4.1 was used instead of 2.5,FDG-PET/CT was more accurate in assessing nodal metastasis.Amos JM Ela Bella Ya-Rui Zhang Wei Fan Kong-Jia Luo Tie-Hua Rong Peng Lin Hong Yang Jian-Hua Fu 2014Chinese Journal of Cancer2014,33,4:3
5Caspase-3 expression in metastatic lymph nodes of esophageal squamous cell carcinoma is prognostic of survival显示文摘AIM:To assess whether differential expression of caspase-3 in paired metastatic lymph nodes(LNs)is prognostic of survival in patients with resectable esophageal squamous cell carcinoma(ESCC).METHODS:Capases-3 expression was evaluated immunohistochemically in 122 pairs of primary ESCCs and regional metastatic LNs assembled on tissue microarrays.The impact of caspase-3 expression on survival outcomes was analyzed by the Kaplan-Meier method and Cox proportional hazards regression model.RESULTS:The level of caspase-3 expression was significantly higher in LN metastases than in primary tumors(P<0.001).Caspase-3 expression in the primary tumors was associated with longer median survival(23 mo vs21 mo,P=0.033),whereas higher expression in paired metastatic LNs was associated with shorter median survival(20 mo vs 22 mo,P=0.043).Multivariate analysis showed that both were independent prognostic factors.CONCLUSION:Caspase-3 expression in metastatic LNs may be a potential independent predictor of poorer overall survival in patients with resected ESCC and LN metastasis.Protein expression in metastatic tumors may be a biomarker prognostic of survival.Xiu-Shen Wang Kong-Jia Luo Amos Ela Bella Shan-Shan Bu Jing Wen Shui-Shen Zhang Yi Hu 2014World Journal of Gastroenterology2014,20,15:2
6The neuroprotective effect of dexmedetomidine in the hippocampus of rabbits after subarachnoid hemorrhage显示文摘Murat Cosar Olcay Eser Huseyin Fidan Onder Sahin Sadik Buyukbas Yuksel Ela Murat Yagmurca Oguz A. Ozen 2009Surgical Neurology2009,,1:2
7Beta-endorphin neuro-nal cell transplant reduces corticotropin releasing hormone hyperre-sponse to lipopolysaccharide and eliminates natural killer cell func-tional deficiencies in fetal alcohol exposed rats显示文摘Boyadjieva NI Ortigüela M Arjona A 2009Alcohol ClinExp Res2009,33,5:1
8The effect of anode flow characteristics and temperature on the performance of a direct methanol fuel cell显示文摘JOHN C A BRANT A P ELA H 2001Journal of Power Source2001,96,1:1
9Apolipoprotein E ge-notyping method by real time PCR,a fast and cost-effective alternative to the TaqMan and FRET assays显示文摘Calero O Hortigüela R Bullido MJ 0,,02:1
10Automatic thermographic and RGB texture of as-built BIM for energy rehabilitation purposes显示文摘Lagüela S Díaz-Vilari(n)o L Martinez J 0,,:1
11Synthesis and structure–activity relationships of a novel series of pyrimidines as potent inhibitors of TBK1/IKKε kinases显示文摘Edward G. McIver Justin Bryans Kristian Birchall Jasveen Chugh Thomas Drake Stephen J. Lewis Joanne Osborne Ela Smiljanic-Hurley William Tsang Ahmad Kamal Alison Levy Michelle Newman Debra Taylor J. Simon C. Arthur Kristopher Clark Philip Cohen 2012Bioorganic & Medicinal Chemistry Letters2012,,23:1
12Superouvlation in the buffalo : consrtaints and manipulation 显示文摘ABUOL - ELA M B E 2000Buafflo Jounral2000,1,:1
132-median in trees with pos/neg weights显示文摘Burkard R E (ela E Dollani H 2000Discrete Applied Mathematics2000,105,3:1
14Identification of P -glycoprotein substrates and inhibitors among psychoactive compounds -implications for pharmacokinetics of selected sustrates 显示文摘Ela AA Hartter C Schmitt U 2004J Pharm Pharmacol2004,56,:1
15Administration, distribution, metabolism and elimination of polymer therapeutics显示文摘Ela Markovsky Hemda Baabur-Cohen Anat Eldar-Boock Liora Omer Galia Tiram Shiran Ferber Paula Ofek Dina Polyak Anna Scomparin Ronit Satchi-Fainaro 2011Journal of Controlled Release2011,,2:1
16Glutathione deficiency and human immunodeficiancy virus infection显示文摘STAAL F J ELA S W ROEDERER M 1992Lancet1992,339,:1
17Nitrogen transformations during soil-aquifer treatment of wastewater effluent-oxygen effects in field studies 显示文摘Miller J H Ela W P Lansey K E 2006J Environ EngASCE2006,132,10:1
18Identification of Pglycoprotein substrates and inhibitors among psychoactive compounds-implications for pharmacokinetics of selected substrates显示文摘 Hartter S Schmitt U 2004J Pharm Pharmacol2004,56,8:1
19Perylene imide dyes for solid state dye sensitized solar cells: Spectroscopy, energy levels and photovoltaic performance 显示文摘ERTEN ELA S TURKMEN G 2011Renewable Energy2011,36,6:1
20Glutathione deficiency and human immunodeficiency virus infection显示文摘Staal F J T Ela S W Roederer M 1992The Lancet1992,339,:1
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