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| 1 | Effect of probiotic Lactobacillus plantarum Dad-13 powder consumption on the gut microbiota and intestinal health of overweight adults显示文摘BACKGROUND Shifting on lifestyle,diet,and physical activity contributed on increasing number of obese people around the world.Multiple factors influence the development of obesity.Some research suggested that gut microbiota(GM)plays an important role in nutrient absorption and energy regulation of individuals,thus affecting their nutritional status.Report of Indonesia Basic Health Research showed that the prevalence of obesity in every province tended to increase.Although the root cause of obesity is excessive calorie intake compared with expenditure,the differences in gut microbial ecology between healthy and obese humans may affect energy homeostasis.GM affect body weight,especially obesity.Probiotics that are consumed while alive and able to colonize in the intestine are expected to increase the population of good bacteria,especially Bifidobacteria and Lactobacilli,and suppress pathogens such as Enterobacteriaceae and Staphylococcus.The strain of L.plantarum Dad-13 has been demonstrated to survive and colonize in the gastrointestinal tract of healthy Indonesian adults who consume fermented milk containing L.plantarum Dad-13.The consumption of probiotic L.plantarum Dad-13 powder decreased E.coli and non-E.coli coliform bacteria in school-aged children in Indonesia.L.plantarum is a dominant bacterium in the average Indonesian’s GM.For this reason,this bacterium is probably a more suitable probiotic for Indonesians.AIM To determine the effect of the consumption of indigenous probiotic Lactobacillus plantarum Dad-13 powder in overweight adults in Yogyakarta(Indonesia).METHODS Sixty overweight volunteers with a body mass index(BMI)equal to or greater than 25 consume indigenous probiotic powder L.plantarum Dad-13(2×109 CFU/gram/sachet)for 90 d.The study was a randomized,double-blind,placebocontrolled study.The volunteers filled in a diary on a daily basis,which consisted of questions on study product intake(only during ingestion period),other food intake,number of bowel movements,fecal quality(consistency and color),any medications received,and any symptom of discomfort,such as diarrhea,constipation,vomiting,gassing,sensation of illness,etc.Fecal samples and the subjects’diaries were collected on the morning of day 10+1,which was marked as the end of the baseline period and the start of the ingestion period.During the ingestion period(from day 11 to day 101),several parameters to measure and analyze the results included body weight and height(once a month),the lipid profile,GM analysis using MiSeq,short-chain fatty acid(SCFA)analysis using gas chromatography,and the measurement of fecal pH using a pH meter.RESULTS The consumption of indigenous probiotic powder L.plantarum Dad-13 caused the average body weight and BMI of the probiotic group to decrease from 84.54±17.64 kg to 83.14±14.71 kg and 33.10±6.15 kg/m2 to 32.57±5.01 kg/m2,respectively.No significant reduction of body weight and BMI in the placebo group was observed.An analysis of the microbiota showed that the number of Bacteroidetes,specifically Prevotella,increased significantly,while that of Firmicutes significantly decreased.No significant change in lipid profile in both groups was found.Also,no significant change in SCFAs(e.g.,butyrate,propionate,acetic acid)and pH level was found after the consumption of the probiotic.CONCLUSION No significant differences in pH before and after ingestion were observed in both the probiotic and placebo groups as well as in the lipid profile of both cholesterol and triglyceride,high-density lipoprotein(HDL),low-density lipoprotein(LDL),and the LDL/HDL ratio.In addition,no significant changes in the concentration of SCFAs(e.g.,acetic acid,propionate,and butyrate)were found after consumption.Interestingly,a significant decrease in body weight and BMI(P<0.05)was determined in the treatment group.An analysis of GM shows that L.plantarum Dad-13 caused the Firmicutes population to decrease and the Bacteroidetes population(especially Prevotella)to increase. | Endang Sutriswati Rahayu Mariyatun Mariyatun Nancy Eka Putri Manurung Pratama Nur Hasan Phatthanaphong Therdtatha Riko Mishima Husnita Komalasari Nurul Ain Mahfuzah Fathyah Hanum Pamungkaningtyas Wahyu Krisna Yoga Dina Aulia Nurfiana Stefanie Yolanda Liwan Mohammad Juffrie Agung Endro Nugroho Tyas Utami | 2021 | World Journal of Gastroenterology2021，27，1： | 6 |
| 2 | Understanding divergent domestication traits from the whole-genome sequencing of swamp-and river-buffalo populations显示文摘Domesticated buffaloes have been integral to rice-paddy agro-ecosystems formillennia,yet relatively little is known about the buffalo genomics.Here,we sequenced and assembled reference genomes for both swamp and river buffaloes and we re-sequenced 230 individuals(132 swamp buffaloes and 98 river buffaloes)sampled from across Asia and Europe.Beyond the many actionable insights that our study revealed about the domestication,basic physiology and breeding of buffalo,we made the striking discovery that the divergent domestication traits between swamp and river buffaloes can be explained with recent selections of genes on social behavior,digestion metabolism,strengths and milk production. | Xier Luo Yu Zhou Bing Zhang Yi Zhang Xiaobo Wang Tong Feng Zhipeng Li Kuiqing Cui Zhiqiang Wang Chan Luo Hui Li Yanfei Deng Fenghua Lu Jianlin Han Yongwang Miao Huaming Mao Xiaoyan Yi Cheng Ai Shigang Wu Alun Li Zhichao Wu Zijun Zhuo Do Da Giang Bikash Mitra Mohammad Farhad Vahidi Shahid Mansoor Sahar Ahmed Al-Bayatti Eka Meutia Sari Neena Amatya Gorkhali Sigit Prastowo Laiba Shafique Guoyou Ye Qian Qian Baoshan Chen Deshun Shi Jue Ruan Qingyou Liu | 2020 | National Science Review2020，7，3： | 3 |
| 3 | Adjunctive platelet-rich plasma and hyaluronic acid injection after arthroscopic debridement in Kellgren-Lawrence grade 3 and 4 knee osteoarthritis显示文摘BACKGROUND Osteoarthritis(OA)is the most common cause of pain and disability,predominantly affecting the knee.The current management of knee OA falls short of completely stopping disease progression,particularly in Kellgren-Lawrence(KL)grade 3 and 4 knee OA.As such,joint replacement is often recommended,although only 15%-33%of candidates accept it.Alternative therapeutic options are still needed to prevent the progression of joint damage and delay the need for knee arthroplasty.AIM To investigate the effect of adjunctive platelet rich plasma(PRP)and hyaluronic acid(HA)after arthroscopic debridement in KL grade 3 and 4 knee OA.METHODS This retrospective cohort study used the Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC)score and WOMAC sub-scores(pain,stiffness,and function)to assess 21 patients,grouped according to medical record data of treatment received:Arthroscopic debridement(n=7);arthroscopic debridement with PRP(n=7);or arthroscopic debridement with HA(n=7).WOMAC scores and sub-scores at baseline and at 3 mo and 5 mo posttreatment were recorded.The three-group data were statistically analyzed using the tests of paired t,one-way analysis of variance,and post hoc least significant difference.RESULTS All three treatment groups showed significant improvements in WOMAC score and sub-scores from before treatment to 3 mo and 5 mo after treatment.However,the arthroscopic debridement with PRP treatment group,in particular,showed a significantly lower WOMAC pain score than the group who received arthroscopic debridement alone at 5 mo after the procedure(P=0.03).CONCLUSION Compared to arthroscopic debridement alone,adjunctive PRP after arthroscopic debridement significantly lessened the patients’pain symptom. | Henry Tirtosuharto I Gede Eka Wiratnaya Putu Astawa | 2022 | World Journal of Orthopedics2022，13，10： | 2 |
| 4 | Prenatal diagnosis and molecular genetic studies on a new case of ag- nathia-otocephaly显示文摘 | Kanmasaran D Morin F C ekas J | 2010 | Fetal Pediatr Pathol2010，29，4： | 1 |
| 5 | Prediction of local recurrence,distant metastases,and death after breastconserving therapy in early-stage invasive breast cancer using afive-biomarker panel显示文摘 | Millar EKA Graham PH O'Toole SA | 2009 | J Clin Oncol2009，27，28： | 1 |
| 6 | Genetic Algorithms in Computer Aided Design显示文摘 | Ga'bor Rennera Aniko' Eka'rta | 2003 | Computer-Aided Design2003，35，： | 1 |
| 7 | Organizational Citizenship Behav- ior Role in Mediating the Effect of Transformational Leader- ship, Job Satisfaction on Employee Performance:Studies in PT Bank Syariah 显示文摘 | Maharani V T Eka A N | 2013 | Mandiri Malang East Java2013，8，17： | 1 |
| 8 | Review article:analysis of emulsifier in food using chromatographic techniques显示文摘 | Abdul Rohman Yaakob B Che Man Eka Noviana | 2013 | Journal of Food and Pharmaceutical Sciences2013，1，3： | 1 |
| 9 | Effect of probiotic L. plantarum IS-10506 and zinc supplementation on humoral immune response and zinc status of Indonesian pre-school children显示文摘 | Ingrid S. Surono Pratiwi D. Martono Satomi Kameo Eka W. Suradji Hiroshi Koyama | 2014 | Journal of Trace Elements in Medicine and Biology2014，，4： | 1 |
| 10 | Ecosystem carbon stock of a tropical mangrove forest in North Sulawesi, Indonesia显示文摘Recent studies have highlighted the valuable role played by mangrove forests in carbon sequestration and storage.Although Indonesia accounts for a large proportion of global mangrove area, knowledge on the carbon stock and sources in the Indonesian mangrove is still limited. In this study, we quantified the ecosystem organic carbon(OC) stock and its spatial variation at an oceanic mangrove in Wori, North Sulawesi, Indonesia. The sources of soil OC were also investigated. The results showed that the mangrove soil had a substantial OC stock containing15.4 kg/m^2(calculated by carbon) in the top 50 cm soil, and represented the majority of the ecosystem OC stock at the Wori mangrove. The mangrove biomass and ecosystem OC stock were 8.3 kg/m^2 and 23.7 kg/m^2, respectively.There was no significantly difference in the soil OC stock among the stations with difference distances offshore,while the highest mangrove biomass OC stock was found at the seaward station. Isotope mixing calculations showed that the rich OC in mangrove soils was attributed to the accumulated autochthonous mangrove source while the suspended organic matter in tidal water and the mangrove-adjacent seagrass contributed less than 20%to the soil OC. The results further demonstrated the importances of the oceanic mangrove in carbon storage and the mangrove plants in contributing OC to their soils. | CHEN Shunyang CHEN Bin SASTROSUWONDO Pramudji DHARMAWAN I Wayan Eka OU Danyun YIN Xijie YU Weiwei CHEN Guangcheng | 2018 | Acta Oceanologica Sinica2018，37，12： | 1 |
| 11 | et al Techno- economic analysis of a stand-alone hybrid photovoltaic-diesel - battery fuel cell power system 显示文摘 | KARAKOULIDIS K MAVRIDIS K BANI)EKAS D | 2011 | Renewable Energy2011，36，18： | 1 |
| 12 | Bioelectricalimpedance analysis of frozen sea bass(Dicentrarchus labrax)显示文摘 | Vidacˇeka S Medic'a H Botka-Petrak K | 2008 | Journal of Food Engineering2008，88，2： | 1 |
| 13 | Apodized dif- fractive versus refractive multifocal intraocular lenses optical and visual evaluation 显示文摘 | Zelichow ska B R ekas M Stankiew icz A | 2008 | J Cataract Surg2008，34，12： | 1 |
| 14 | Horizontal equity in the delivery of health care 显示文摘 | Wagstaff A Doorslaer EKA Paci P | 1991 | J Health Econ1991，10，2： | 1 |
| 15 | Factors associated with case fatality of human H5N1 virus infections in Indonesia: a case series显示文摘 | I Nyoman Kandun Erna Tresnaningsih Wilfried H Purba Vernon Lee Gina Samaan Syahrial Harun Eka Soni Chita Septiawati Tetty Setiawati Elvieda Sariwati Toni Wandra | 2008 | The Lancet2008，，9640： | 1 |
| 16 | Alterations of GABAA and glutamate receptor subunits and heat shockprotein in rat hippocampus following traumatic brain injury and in posttraumatic epilepsy 显示文摘 | Elena A Kharlamov Eka Lepsveridze Maia Meparishvili | 2011 | Epilepsy Research2011，95，12： | 1 |
| 17 | Laboratory Evaluation of Using Lig- hosulfonate and Surfactant Mixture in CO2 Flooding 显示文摘 | Andy Eka Syahput ra | | SPE0，，： | 1 |
| 18 | Adaptation to daily stress among mothers of children with an autism spectrum disorder:The role of daily positive affect显示文摘 | Ekas NV Whitman TL | | 0，，09： | 1 |
| 19 | Early Temperament and Attachment Security with Mothers and Fathers as Predictors of Toddler Compliance and Noncompliance显示文摘 | Diane M. Lickenbrock Julia M. Braungart‐Rieker Naomi V. Ekas Shannon R. Zentall Toko Oshio Elizabeth M. Planalp | 2013 | Inf. Child. Dev2013，，6： | 1 |
| 20 | Genetic algorithms in computer aided design 显示文摘 | Ga'bor Bennera Aniko' Eka'rta | 2003 | Computer-Aided Design2003，35，： | 1 |
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