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| 1 | Imaging evaluation of traumatic thoracolumbar spine injuries: Radiological review显示文摘Spine fractures account for a large portion of musculoskeletal injuries worldwide. A classification of spine fractures is necessary in order to develop a common language for treatment indications and outcomes. Several classification systems have been developed based on injury anatomy or mechanisms of action, but they have demonstrated poor reliability, have yielded little prognostic information, and have not been widely used. For this reason, the Arbeitsgemeinschaftfür Osteosynthesefragen(AO) committee has classified thorocolumbar spine injuries based on the pathomorphological criteria into3 types(A: Compression; B: Distraction; C: Axial torque and rotational deformity). Each of these types is further divided into 3 groups and 3 subgroups reflecting progressive scale of morphological damage and the degree of instability. Because of its highly detailed sub classifications, the AO system has shown limited interobserver variability. It is similar to its predecessors in that it does not incorporate the patient's neurologic status.The need for a reliable, reproducible, clinically relevant, prognostic classification system with an optimal balance of ease of use and detail of injury description contributed to the development of a new classification system, the thoracolumbar injury classification and severity score(TLICS). The TLICS defines injury based on three clinical characteristics: injury morphology, integrity of the posterior ligamentous complex, and neurologic status of the patient. The severity score offers prognostic information and is helpful in decision making about surgical vs nonsurgical management. | Shivanand Gamanagatti Deepak Rathinam Krithika Rangarajan Atin Kumar Kamran Farooque Vijay Sharma | 2015 | World Journal of Radiology2015，7，9： | 18 |
| 2 | Ebola virus disease: past, present and future显示文摘Ebola virus disease is one of the most deadly ailments known to mankind due to its high mortality rate(up to 90%) accompanying with the disease. Ebola haemorrhagic fever(EHF) is an infectious disease of animal that can be transmitted to both human and non-human primates. The first epidemic of EHF occurred in 1976 in the Democratic Republic of the Congo. The incubation period of ebola is less than 21 days. Ebola virus infections are depicted by immune suppression and a systemic inflammatory response that leads to damage of the vascular, coagulation and immune systems, causing multi-organ failure and shock. Five genetically distinct members of the Filoviridae family responsible for EHF are as follows: Zaire ebolavirus, Sudan ebolavirus, C?te d'Ivoire ebolavirus, Bundibugyo ebolavirus and Reston ebolavirus. The ongoing 2014 West Africa ebola epidemic has been considered as the most serious panic in the medical field with respect to both the number of human cases and death toll. The natural host for ebola virus is unknown, thus it is not possible to carry out programs to regulate or abolish virus from transmission to people. The ebola virus infection provides little chance to develop acquired immunity causing rapid progression of the disease. It is pertinent to mention that at present, there is no antiviral therapy or vaccine that is helpful against ebola virus infection in humans. The impediment of EHF necessitates much better understanding of the epidemiology of the disease, particularly the role of wildlife, as well as bats, in the spread of ebola virus to humans. | Harish Rajak Deepak Kumar Jain Avineesh Singh Ajay Kumar Sharma Anshuman Dixit | 2015 | Asian Pacific Journal of Tropical Biomedicine2015，5，5： | 4 |
| 3 | Predicting suitability of different scale-dependent dispersivities for reactive solute transport through stratified porous media显示文摘In this paper,the behavior of breakthrough curves(BTCs) for reactive solute transport through stratified porous media is investigated.A physical laboratory model for layered porous media was constructed,in which thin layer of gravel was sandwiched in between two thick layers of natural soil.Gravel layer and natural soil layers were hydraulically connected as single porous continuum.A constant source of tracer was connected through gravel layer and elucidated at different sampling points in the direction of flow.Flexible multiprocess non-equilibrium(MPNE) transport equation with scale-dependent dispersivity function was used to simulate experimental BTCs of reactive solute transport through layered porous media.The values of equilibrium sorption coefficient and other input parameters were obtained experimentally.The simulation of BTC was performed using MPNE model with scale-dependent dispersivity.The simulation of different scale-dependent dispersivities was then compared and it was found that for field scale of estimation of dispersivity,asymptotic and exponential dispersivity functions performed better.In continuation to the comparison of simulated BTCs obtained using different models,spatial moment analysis of each aforesaid scale-dependent dispersivity model was also done.Spatial moment analysis provides the information related to mean solute mass,rate of mass travel,and mean plume dispersion.Linear and constant dispersivities showed higher variance as compared to asymptotic and exponential dispersion functions.This supports the field applicability of asymptotic and exponential dispersivity functions.The BTCs were also found to elucidate a nonzero concentration with time,which was clearly affected by physical non-equilibrium.In natural condition,such information is required in effective aquifer remediation process. | Deepak Swami Abhimanyu Sharma Pramod Kumar Sharma Dericks P.Shukla | 2016 | Journal of Rock Mechanics and Geotechnical Engineering2016，8，6： | 2 |
| 4 | Design of Combretastatin A-4 Analogs as Tubulin Targeted Vascular Disrupting Agent with Special Emphasis on Their Cis-Restricted Isomers显示文摘 | Harish Rajak Pramod Kumar Dewangan Vijay Patel Deepak Kumar Jain Avineesh Singh Ravichandran Veerasamy Prabodh Chander Sharma Anshuman Dixit | 2013 | Current Pharmaceutical Design2013，，10： | 1 |
| 5 | Extent of mismatch between the period of circadian clocks and light/dark cycles determines time-to-emergence in fruit flies显示文摘当光 / 黑暗(LD ) 周期限定成年人的出现时,生理节奏的钟预定水果苍蝇果蝇 melanogaster 的发展舞台,仅仅在 “allowed gate.” 期间让步以前的研究表明了 time-to-emergence 能被变化在核心钟基因时期改变(每) ,或由改变 LD 周期的长度。因为这条证据在遗传上操作的苍蝇上,或在与时期的有限范围在 LD 周期下面维持的苍蝇上来自研究,能被拉的推论是有限的。而且, time-to-emergence 弄短或变长的程度仍然保持还未知。以便进一步追求这,我们 D 的 assayed time-to-emergence。在 12 不同 LD 下面的 melanogaster 象在经常的光(LL ) 和经常的黑暗条件(DD ) 一样骑车。在苍蝇的 Time-to-emergence 比在 LD 周期和 DD 在 LL 下面更早发生了。在 LD 周期之中, time-to-emergence 在 T4-T8 下面更早发生了,由 T36-T48 ,然后 T12-T32 列在后面,建议当 LD 的长度骑车时,在苍蝇的那 egg-to-emergence 持续时间变得更短从 24 h 背离,适用一强壮积极并且与白天的稍微否定的关联长度,为比 24 h 更短、长的价值,分别地。这些结果建议在生理节奏的钟和环境周期的时期之间的失配的程度在果蝇决定 time-to-emergence。 | Pankaj Yadav Deepak Choudhury Madhumala K. Sadanandappa Vijay Kumar Sharma | 2015 | Insect Science2015，22，4： | 1 |
| 6 | Novel actions of progesterone: what we know today and what will be the scenario in the future?显示文摘 | Shilpa N. Kaore Deepak Kumar Langade Vijay Kumar Yadav Parag Sharma Vijay R. Thawani Raj Sharma | 2012 | Journal of Pharmacy and Pharmacology2012，，8： | 1 |
| 7 | Autonomic Dysfunctions in Patients with Inflammatory Bowel Disease in Clinical Remission显示文摘 | Purnima Sharma Govind K. Makharia Vineet Ahuja Sada Nand Dwivedi Kishore Kumar Deepak | 2009 | Digestive Diseases and Sciences2009，，： | 1 |
| 8 | Biotransformation,multifunctional recycling mechanism of nanostructures,and evaluation of the safety of nanoscale materials显示文摘Current evidence of concept analyses recommending nanotechnology for biomedical uses abounds in recent research. The area of biotechnology interfaces with nanostructures, reconfigures their composition, and alters their characteristics;which influences the dispersion of the particles, the biotransformation they cause, and their potential toxic effect. It is vital to link the idea of the lifecycle of nanostructures to the biological impacts and use methodologies to identify, estimate, and track the gradual bioprocessing of nanostructures in vivo, from a body-wide level to a nanoscopic size. This is necessary because understanding how nanostructures processing, degradation, persistence, and recycling predict potential exposure risks. The safe implementation of nanotechnology-based products in biomedical applications necessitates an extensive understanding of the recycling and transformations of nanomaterials in a living organism. Long-term fate in the body is crucial, as it governs potential environmental risks to human health. Strategies may be used to manage the long-term outcome of nanostructures in an organism since, in addition to composition, their design also affects how long they last and how easily they degrade. The lifespan of nanoparticles, a flexible and biocompatible category of nanostructures that have made it into clinical trials, is the subject of this article. Strategies may be used to manage the long-term outcome of nanoparticles in an organism since, in addition to composition, their design also affects how long they last and how easily they degrade. This review explained the safety of nanoscale materials, biotransformation, and the multifunctional recycling mechanism of nanostructures. | Debjyoti Talukdar Parveen Kumar Benu Chaudhary Deepak Sharma Nishant Yadav Obaid Afzal Abdulmalik Saleh Alfawaz Altamimi Waleed Hassan Almalki Sami IAlzarea Imran Kazmi Ashutosh Pareek Gaurav Gupta Madan Mohan Gupta | 2023 | Particuology2023，，11： | 0 |
| 9 | An unusual cause of simultaneous common bile and pancreatic duct dilation显示文摘Simultaneous dilation of both the common bile duct and the pancreatic duct(double-duct sign)is usually because of ampullary or pancreatic tumours.Here we report an unusual cause of double-duct dilation;we describe the case of a 49-year-old female who developed afferent loop syndrome after pylorus-preserving pancreaticoduodenectomy:crosssectional imaging of the abdomen revealed a double-duct sign. | Puneet Chhabra Surinder Singh Rana Vishal Sharma Ravi Sharma Rajesh Gupta Deepak Kumar Bhasin | 2015 | Gastroenterology Report2015，3，3： | 0 |
| 10 | Neutronic analysis of Indian helium-cooled solid breeder tritium breeding module for testing in ITER显示文摘India has proposed the helium-cooled solid breeder blanket concept as a tritium breeding module to be tested in ITER.The module has lithium titanate for tritium breeding and beryllium for neutron multiplication.Beryllium also enhances tritium breeding.A design for the module is prepared for detailed analysis.Neutronic analysis is performed to assess the tritium breeding rate,neutron distribution,and heat distribution in the module.The tritium production distribution in submodules is evaluated to support the tritium transport analysis.The tritium breeding density in the radial direction of the module is also assessed for further optimization of the design.The heat deposition profile of the entire module is generated to support the heat removal circuit design.The estimated neutron spectrum in the radial direction also provides a more in-depth picture of the nuclear interactions inside the material zones.The total tritium produced in the HCSB module is around 13.87 mg per full day of operation of ITER,considering the 400 s ON time and 1400 s dwell time.The estimated nuclear heat load on the entire module is around 474 kW,which will be removed by the high-pressure helium cooling circuit.The heat deposition in the test blanket model(TBM)is huge(around 9 GJ)for an entire day of operation of ITER,which demonstrates the scale of power that can be produced through a fusion reactor blanket.As per the Brayton cycle,it is equivalent to 3.6 GJ of electrical energy.In terms of power production,this would be around 1655 MWh annually.The evaluation is carried out using the MCNP5 Monte Carlo radiation transport code and FEDNL 2.1 nuclear cross section data.The HCSB TBM neutronic performance demonstrates the tritium production capability and high heat deposition. | H L SWAMI Deepak SHARMA C DANANI P CHAUDHARI R SRINIVASAN Rajesh KUMAR | 2022 | Plasma Science and Technology2022，24，6： | 0 |
| 11 | Technology Landscape for Epidemiological Prediction and Diagnosis of COVID-19显示文摘The COVID-19 outbreak initiated from the Chinese city of Wuhanand eventually affected almost every nation around the globe. From China,the disease started spreading to the rest of the world. After China, Italybecame the next epicentre of the virus and witnessed a very high death toll.Soon nations like the USA became severely hit by SARS-CoV-2 virus. TheWorld Health Organisation, on 11th March 2020, declared COVID-19 a pandemic. To combat the epidemic, the nations from every corner of the worldhas instituted various policies like physical distancing, isolation of infectedpopulation and researching on the potential vaccine of SARS-CoV-2. Toidentify the impact of various policies implemented by the affected countrieson the pandemic spread, a myriad of AI-based models have been presented toanalyse and predict the epidemiological trends of COVID-19. In this work, theauthors present a detailed study of different articial intelligence frameworksapplied for predictive analysis of COVID-19 patient record. The forecastingmodels acquire information from records to detect the pandemic spreadingand thus enabling an opportunity to take immediate actions to reduce thespread of the virus. This paper addresses the research issues and correspondingsolutions associated with the prediction and detection of infectious diseaseslike COVID-19. It further focuses on the study of vaccinations to cope withthe pandemic. Finally, the research challenges in terms of data availability,reliability, the accuracy of the existing prediction models and other open issuesare discussed to outline the future course of this study. | Siddhant Banyal Rinky Dwivedi Koyel Datta Gupta Deepak Kumar Sharma Fadi Al-Turjman Leonardo Mostarda | 2021 | Computers, Materials & Continua2021，，5： | 0 |
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