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| 1 | Optical properties of human normal small intestine tissue determined by Kubelka-Munk method in vitro显示文摘AIM: To study the optical properties of human normal small intestine tissue at 476.5 nm, 488 nm, 496.5 nm, 514.5 nm,532 nm, 808 nm wavelengths of laser irradiation.METHODS: A double-integrating-sphere system, the basic principle of measuring technology of light radiation, and an optical model of biological tissues were used in the study.RESULTS: The results of measurement showed that there were no significant differences in the absorption coefficients of human normal small intestine tissue at 476.5 nm, 488 nm,496.5 nm laser in the Kubelka-Munk two-flux model (P>0.05).The absorption coefficients of the tissue at 514.5 nm, 532 nm,808 nm laser irradiation were obviously increased with the decrease of these wavelengths. The scattering coefficients of the tissue at 476.5 nm, 488 nm, 496.5 nm laser irradiation were increased with the decrease of these wavelengths.The scattering coefficients at 496.5 nm, 514.5 nm, 532 nm laser irradiation were obviously increased with the increase of these wavelengths. The scattering coefficient of the tissue at 532 nm laser irradiation was bigger than that at 808 nm.There were no significant differences in the total attenuation coefficient of the tissue at 476.5 nm and 488 nm laser irradiation (P>0.05). The total attenuation coefficient of the tissue at 488 nm, 496.5 nm, 514.5 nm, 532 nm, 808 nm laser irradiation was obviously increased with the decrease of these wavelengths, and their effective attenuation coefficient revealed the same trend. There were no significant differences among the forward scattered photon fluxe,backward scattered photon fiuxe, and total scattered photon fiuxe of the tissue at 476.5 nm, 488 nm, 496.5 nm laser irradiation. They were all obviously increased with attenuation of tissue thickness. The attenuations of forward and backward scattered photon fluxes, and the total scattered photon fiuxe of the tissue at 514.5 nm laser irradiation were slower than those at 476.5 nm, 488 nm, 496.5 nm laser irradiation respectively. The attenuations of forward and backward scattered photon fluxes, and total scattered photon fluxes at 532 nm laser irradiation were obviously slower than those at 476.5 nm, 488 nm, 496.5 nm, 514.5 nm laser irradiation. The attenuations of forward and backward scattered photon fluxes, and total scattered photon fiuxe at 808 nm laser irradiation were all obviously slower than those at 476.5 nm, 488 nm, 496.5 nm, 514.5 nm, 532 nm laser irradiation respectively.CONCLUSION: There are significant differences in optical parameters of human normal small intestine tissue in the Kubelka-Munk two-flux model at six different wavelengths of laser radiation. The results would provide a new method of information analysis for clinical diagnosis. | Hua-JiangWei DaXing Guo-YongWu YingJin Huai-MinGu | 2003 | World Journal of Gastroenterology2003，9，9： | 4 |
| 2 | Determination of optical properties of normal and adenomatous human colon tissues in vitro using integrating sphere techniques显示文摘AIM: The purpose of the present study is to compare the optical properties of normal human colon mucosa/submucosa and muscle layer/chorion, and adenomatous human colon mucosa/submucosa and muscle layer/chorion in vitro at 476.5, 488, 496.5, 514.5 and 532 nm. We believe these differences in optical properties should help differential diagnosis of human colon tissues by using optical methods.METHODS: In vitro optical properties were investigated for four kinds of tissues: normal human colon mucosa/submucosa and muscle layer/chorion, and adenomatous human colon mucosa/submucosa and muscle layer/chorion. Tissue samples were taken from 13 human colons (13 adenomatous, 13 normal). From the normal human colons a total of 26 tissue samples, with a mean thickness of 0.40 mm, were used (13 from mucosa/submucosa and 13 from muscle layer/chorion), and from the adenomatous human bladders a total of 26 tissue samples, with a mean thickness of 0.40 mm, were used (13 from mucosa/submucosa and 13 from muscle layer/chorion). The measurements were performed using a double-integratingsphere setup and the optical properties were assessed from these measurements using the adding-doubling method that was considered reliable.RESULTS: The results of measurement showed that there were significant differences in the absorption coefficients and scattering coefficients between normal and adenomatous human colon mucosa/submucosa at the same wavelength,and there were also significant differences in the two optical parameters between both colon muscle layer/chorion at the same wavelength. And there were large differences in the anisotropy factors between both colon mucosa/submucosa at the same wavelength, there were also large differences in the anisotropy factors between both colon muscle layer/chorion at the same wavelength.There were large differences in the value ranges of the absorption coefficients, scattering coefficients and anisotropy factors between both colon mucosa/submucosa,and there were also large differences in these value ranges between both colon muscle layer/chorion. There are the same orders of magnitude in the absorption coefficients for four kinds of colon tissues. The scattering coefficients of these tissues exceed the absorption coefficients by at least two orders of magnitude.CONCLUSION: There were large differences in the three optical parameters between normal and adenomatous human colon mucosa/submucosa at the same laser wavelength, and there were also large differences in these parameters between both colon muscle layer/chorion at the same laser wavelength. Large differences in optical parameters indicate that there were large differences in compositions and structures between both colon mucosa/submucosa, and between both colon muscle layer/chorion.Optical parameters for four kinds of colon tissues are wavelength dependent, and these differences would be useful and helpful in clinical applications of laser and tumors photodynamic therapy (PDT). | Hua-JiangWei DaXing Jian-JunLu Huai-MinGu Guo-YongWu YingJin | 2005 | World Journal of Gastroenterology2005，11，16： | 2 |
| 3 | RNA-mediated chromatin-based silencing in plants显示文摘 | Marjori Matzke Tatsuo Kanno Lucia Daxinger Bruno Huettel Antonius JM Matzke | 2009 | Current Opinion in Cell Biology2009，，3： | 2 |
| 4 | RNA-directed DNA methylation mediated by DRD1 and Pol IVb: A versatile pathway for transcriptional gene silencing in plants显示文摘 | Bruno Huettel Tatsuo Kanno Lucia Daxinger Etienne Bucher Johannes van der Winden Antonius J.M. Matzke Marjori Matzke | 2007 | BBA - Gene Structure and Expression2007，，5： | 1 |
| 5 | Evidence for nuclear processing of plant micro RNA and short interfering RNA precursors显示文摘 | Papp I Mette M F Aufsatz W Daxinger L Schauer S E | 2003 | Plant Physiol2003，132，： | 1 |
| 6 | Thyroid cancer incidence in China between 2005 and 2009显示文摘 | Xufeng Fei Daxing Yang Zhe Kong Zhaohan Lou Jiaping Wu | 2014 | Stochastic Environmental Research and Risk Assessment2014，，： | 1 |
| 7 | Necrosis of cervical carcinoma by dichloroacetate released from electrospun polylactide mats显示文摘 | Daxing Liu Shi Liu Xiabin Jing Xiaoyuan Li Wenliang Li Yubin Huang | 2012 | Biomaterials2012，，17： | 1 |
| 8 | Immunomodulatory effectiveness of tacrolimus in preventing epidural scar adhesion after laminectomy in rat model显示文摘 | Lianqi Yan Xiaolei Li Jingcheng Wang Sun Yu Daxing Wang Jiaxiang Gu Jinshan He Hansheng Hu Gang Chen Qiang Wang Xinmin Feng | 2012 | European Journal of Pharmacology2012，，： | 1 |
| 9 | Expression, purification and antibody preparation using different constructs of PCV2 capsid protein显示文摘 | Fuwang Chen Xin Yang Daxing Pang Zhiyuan Peng Meichen Dong Xiaoyun Liu Hongsheng Ouyang Linzhu Ren | 2014 | International Journal of Biological Macromolecules2014，，： | 1 |
| 10 | Comparative analysis of different methods to enhance porcine circovirus 2 replication显示文摘 | Xin Yang Fuwang Chen Yuhang Cao Daxing Pang Hongsheng Ouyang Linzhu Ren | 2012 | Journal of Virological Methods2012，，： | 1 |
| 11 | RNA-mediated chromatin- based silencing in plants 显示文摘 | Matzke M Kanno T Daxinger L | 2009 | C urr Opin Cell Biol2009，21，3： | 1 |
| 12 | Understanding transgenerational epigenetic inheritance via the gametes in mammals显示文摘 | DAXINGER L WHITELAW E | 2012 | Nature Reviews Genetics2012，13，3： | 1 |
| 13 | Understanding transgenerational epigenetic inheritance via the gametes in mammals 显示文摘 | Daxinger L Whitelaw E | 2012 | Nature Re- views Genetics2012，13，3： | 1 |
| 14 | Evidence for nuclear processing of plant microRNA and short interfering RNA precursors显示文摘 | Papp I Mette MF Aufsatz W Daxinger L Schauer SE Ray A van der Winden J Matzke M Matzke AJM | | 0，，： | 1 |
| 15 | Targets of RNA-directed DNA methylation显示文摘 | MATZKE M KANNO T B DAXINGER L | 2007 | Current Opinion in Plant Biology2007，10，5： | 1 |
| 16 | RNA-directed DNA methylation mediated by DRD1 and Pol IVb: A versatile pathway for transcriptional gene silencing in plants 显示文摘 | Huettel B Kanno T Daxinger L et el | 2007 | Biochim Biophys Acta2007，1769，56： | 1 |
| 17 | Bcl‐2 and Bcl‐xL play important roles in the crosstalk between autophagy and apoptosis显示文摘 | FeifanZhou YingYang DaXing | 2011 | FEBS Journal2011，，3： | 1 |
| 18 | Understanding transgenerational epigenetic inheritance via the gametes in mammals显示文摘 | Daxinger L Whitelaw E | 2012 | Nat Rev Genet2012，13，3： | 1 |
| 19 | The Simulation Study of HEV Under Electric Assist Control Strategy (EACS)显示文摘Hybrid Electric Vehicle (HEV) becomes a popular research project all over the world because of its high efficiency and low emissions. HEV is driven by Internal Combustion (IC) engine and electric motor, and its powertrain is more complex than conventional vehicle. Therefore, the complexity of a HEV powertrain demands a reliable control strategy be developed to guarantee stable and consistent operation. In this paper, EACS is proposed which takes IC engine as a main power unit and the electric motor as an assistant one. Because the fuel consumption of HEV mainly depends on IC engine, EACS restricts the IC engine to operate under the condition with favorable fuel economy. In the paper several control parameters are described such as the maximum torque, the lowest and highest desired battery state of charge (SOC), whose values will affect the performance of HEV remarkably. In addition, the test models of power units for HEV, mathematical models of transmission and vehicle dynamics for HEV are established. A forward-facing simulation software (i.e. driver-to-wheel) based on MATLAB/Simulink is developed to test the performance of EACS and determine the proper value of the control parameters. The simulation results and conclusion are also shown in the paper. | 张欣 Wang Daxing Li Congxin | 2004 | High Technology Letters2004，10，2： | 1 |
| 20 | Modeling, Control Design and Performance Analysis of PHEV Powertrain显示文摘Developing Parallel Hybrid Electric Vehicle (PHEV) is becoming an active research field of new type electric automobiles for its high fuel economy and low emissions. Due to the complexity of PHEV powertrain, simulation becomes an important method in study of PHEV control strategy. In this paper, a forward-facing simulation software and the models of PHEV powertrain based on MATLAB/Simulink are developed to study on the PHEV control strategy. The simulation results are also shown in the paper. | 张欣 Wang Daxing | 2004 | High Technology Letters2004，10，1： | 0 |
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