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| 1 | Zircon U-Pb geochronology of basement metamorphic rocks in the Songliao Basin显示文摘Zircon LA-ICP MS U-Pb dating of six metamorphic rocks and a metagranite (breccia) from southern basement of the Songliao Basin are reported in order to constrain the formation ages of basement. The basement metamorphic rocks in the Songliao Basin mainly consist of metagabbro (L45-1), amphibolite (SN117), metarhyolitical tuff (G190), sericite (Ser) schist (N103), chlorite (Chl) schist (T5-1), biotite (Bi)-actinolite (Act)-quartz (Q) schist (Y205), and metagranite (L44-1). The cathodoluminesence (CL) images of the zircons from metagabbro (L45-1) and metagranite (L44-1) indicate that they have cores of magmatic origin and rims of metamorphic overgrowths. Their U-Pb isotopic ages are 1808±21 Ma and 1873±13 Ma, respectively. The zircons with oscillatory zoning from amphibolite (SN117) and Chl schist (T5-1), being similar to those of mafic igneous rocks, yield ages of 274 ± 3.4 Ma and 264 ± 3.2 Ma, re-spectively. The zircons from metarhyolitical tuff (G190) and Ser schist (N103) display typical magmatic growth zoning and yield ages of 424 ± 4.5 Ma and 287 ± 5.1Ma, respectively. Most of zircons from Bi-Act-Q schist (Y205) are round in shape and different in absorption degree in the CL images, implying their sedimentary detritals. U-Pb dating yield concordant ages of 427 ± 3.1Ma, 455 ± 12 Ma, 696 ± 13 Ma, 1384±62 Ma, 1649±36 Ma, 1778±18 Ma, 2450±9 Ma, 2579±10 Ma, 2793±4 Ma and 2953±14 Ma. The above-mentioned results indicate that the Precambrian crystalline basement (1808―1873 Ma) exists in the southern Songliao Basin and could be related to tectonic thrust, and that the Early Paleozoic (424―490 Ma) and Late Paleozoic magmatisms (264―292 Ma) also occur in the basin basement, which are consistent with the ages of the detrital zircons from Bi-Act-Q schist in the basement. | PEI FuPing XU WenLiang YANG DeBin ZHAO QuanGuo LIU XiaoMing HU ZhaoChu | 2007 | Chinese Science Bulletin2007，52，7： | 57 |
| 2 | Delamination and destruction of the North China Craton显示文摘This article presents an overview on recent developments in studies of chemical and physical processes of lithospheric delamination with respect to destruction of the North China Craton. It is emphasized that the pyroxenite source resulting from interaction between eclogite-derived melt and peridotite is a direct consequence of delamination. The pyroxenite source thus formed has unique mineralogical and geochemical features, which characterize Mesozoic basalts of the North China Craton. Melt-peridotite interaction played an important role in refertilization of cratonic lithospheric mantle, leading to density increase, weakening and final destabilization of the North China Craton. The nature of the melt is the key to distinguish mechanisms of destructing this craton. | GAO Shan ZHANG JunFeng XU WenLiang LIU YongSheng | 2009 | Chinese Science Bulletin2009，54，19： | 53 |
| 3 | Permian volcanisms in eastern and southeastern margins of the Jiamusi Massif, northeastern China: zircon U-Pb chronology, geochemistry and its tectonic implications显示文摘LA-ICP-MS zircon U-Pb dating and geochemical data for the Late Paleozoic volcanic rocks from eastern and southeastern margins of the Jiamusi Massif are presented to understand the regional tectonic evolution. Zircons from eight representative volcanic rocks are euhedral-subhedral in shape and dis- play striped absorption and fine-scale oscillatory growth zoning as well as high Th/U ratios (0.33―2.37), implying a magmatic origin. The dating results show that the Late Paleozoic volcanic rocks in the study area can be divided into two stages, i.e., the Early Permian (a weighted mean 206Pb/238U age of 288 Ma) and the Middle Permian volcanisms (a weighted mean 206Pb/238U age of 268 Ma). The former is com- posed mainly of basalt, basaltic-andesite, andesite and minor dacite. They are characterized by low SiO2 contents, high Mg# (0.40―0.59), enrichment in Na (Na2O/K2O = 1.26―4.25) and light rare earth elements (LREEs), relative depletion in heavy rare earth elements (HREEs) and high field strength ele- ments (HFSEs), indicating that an active continental margin setting could exist in the eastern margin of the Jiamusi Massif in the Early Permian. The latter consists mainly of rhyolite and minor dacite with high SiO2 (77.23%―77.52%), low MgO (0.11%―0.14%), enrichment in K2O (Na2O/K2O ratios < 0.80) and Rb, Th, U and depletion in Eu, Sr, P and Ti, implying a crust-derived origin. Therefore, it is proposed that the Middle Permian volcanic rocks could have formed under the collision of the Jiamusi and the Khanka Massifs. | MENG En XU WenLiang YANG DeBin PEI FuPing Yu Yang Zhang XingZhou | 2008 | Chinese Science Bulletin2008，53，8： | 42 |
| 4 | Subduction history of the Paleo-Pacific slab beneath Eurasian continent: Mesozoic-Paleogene magmatic records in Northeast Asia显示文摘This paper presents a review on the rock associations, geochemistry, and spatial distribution of Mesozoic-Paleogene igneous rocks in Northeast Asia. The record of magmatism is used to evaluate the spatial-temporal extent and influence of multiple tectonic regimes during the Mesozoic, as well as the onset and history of Paleo-Pacific slab subduction beneath Eurasian continent. Mesozoic-Paleogene magmatism at the continental margin of Northeast Asia can be subdivided into nine stages that took place in the Early-Middle Triassic, Late Triassic, Early Jurassic, Middle Jurassic, Late Jurassic, early Early Cretaceous, late Early Cretaceous, Late Cretaceous, and Paleogene, respectively. The Triassic magmatism is mainly composed of adakitic rocks,bimodal rocks, alkaline igneous rocks, and A-type granites and rhyolites that formed in syn-collisional to post-collisional extensional settings related to the final closure of the Paleo-Asian Ocean. However, Triassic calc-alkaline igneous rocks in the Erguna-Xing'an massifs were associated with the southward subduction of the Mongol-Okhotsk oceanic slab. A passive continental margin setting existed in Northeast Asia during the Triassic. Early Jurassic calc-alkaline igneous rocks have a geochemical affinity to arc-like magmatism, whereas coeval intracontinental magmatism is composed of bimodal igneous rocks and A-type granites. Spatial variations in the potassium contents of Early Jurassic igneous rocks from the continental margin to intracontinental region, together with the presence of an Early Jurassic accretionary complex, reveal that the onset of the PaleoPacific slab subduction beneath Eurasian continent occurred in the Early Jurassic. Middle Jurassic to early Early Cretaceous magmatism did not take place at the continental margin of Northeast Asia. This observation, combined with the occurrence of low-altitude biological assemblages and the age population of detrital zircons in an Early Cretaceous accretionary complex,indicates that a strike-slip tectonic regime existed between the continental margin and Paleo-Pacific slab during the Middle Jurassic to early Early Cretaceous. The widespread occurrence of late Early Cretaceous calc-alkaline igneous rocks, I-type granites, and adakitic rocks suggests low-angle subduction of the Paleo-Pacific slab beneath Eurasian continent at this time. The eastward narrowing of the distribution of igneous rocks from the Late Cretaceous to Paleogene, and the change from an intracontinental to continental margin setting, suggest the eastward movement of Eurasian continent and rollback of the PaleoPacific slab at this time. | Jie TANG Wenliang XU Feng WANG Wenchun GE | 2018 | Science China Earth Sciences2018，61，5： | 48 |
| 5 | Discovery of eclogite inclusions and its geological significance in early Jurassic intrusive complex in Xuzhou-northern Anhui, eastern China显示文摘The early Jurassic intrusive complex is chiefly made of monzodioritic porphyry in northern Anhui and northern Jiangsu, which emplaced in 191 Ma. The intrusive complexes contain a lot of eclogite inclusions which belong to eclogite and garnet-pyroxenite. The inclusions had undergone eclogite facies high-pressure metamorphism and am-phibolite facies retrogressive metamorphism. The garnets in eclogite inclusions are mainly almandine varieties and clino-pyroxenes are omphacite and augite. The mineral assemblage and P-T estimation results show that P-T conditions of eclogite facies metamorphism and amphibolite facies retrogressive metamorphism are over 1.2-1.5 GPa, 709-861°C and 0.7-1.03 GPa, 666-738°C, respectively. The discovery of the high-pressure xenoliths not only is of important significance to understand the composition and structure of deep crust in southern edge of North China Platform, but also can be of important influence on realizing the subduc-tion-collision-exhumation evolutional process | Wenliang Xu Dongyan Wang Xiaochun Liu Qinghai Wang Jingqian Lin | 2002 | Chinese Science Bulletin2002，47，14： | 37 |
| 6 | SHRIMP zircon U-Pb dating in Jingshan 'migmatitic granite', Bengbu and its geological significance显示文摘The petrographic characteristics of Jingshan 'migmatitic granite' and the occurrence of the magmatic zircons indicate that the granite was formed by normal crystallization of felsic melts. All zircons in the granite have inherited cores and fine-scale oscillatory zoning rims of magmatic origin. It is realized that the granite was formed at 160.2±1.3 Ma through dating magmatic zircons. The generation of the granitic magma could be related to the lithospheric mantle and/or lower crust delamination after the ultrahigh pressure metamorphism (UHPM) in Triassic. Most inherited zircons yield the ages of 217.1±6.6 Ma, which is consistent with the peak UHPM in the Dabie-Sulu orogenic belt. Some of the inherited zircons (433-722 Ma) constitute a discordia line with the upper intercept age of 850+85/-68 Ma and a lower intercept age of 261+100/-140 Ma. These ages imply that the granite could be derived from the partial melting of the crustal materials of the South China Block that was intensively superimposed by the UHPM. The UHPM could be the reason for the major Pb loss at ±220 Ma. | XU Wenliang, WANG Qinghai, YANG Debin, LIU Xiaochun & GUO Jinghui College of Earth Sciences, Jilin University, Changchun 130061, China Institute of Geomechanics, Chinese Academy of Geological Sciences, Beijing 100081, China Institute of Geology & Geophysics, Chinese Academy of Sciences, Beijing 100029, China | 2005 | Science China Earth Sciences2005，48，2： | 32 |
| 7 | LA-ICP-MS zircon U-Pb dating from granitoids in southern basement of Songliao basin:Constraints on ages of the basin basement显示文摘Seven LA-ICP-MS zircon U-Pb datings from granitoids in the southern basement of the Songliao basin were done in order to constrain the ages of the basin basement. The cathodoluminescence (CL) images of the zircons from seven granitoids indicate that they are euhedral-subhedral ones with striped ab-sorption and obvious oscillatory zoning rims. The dating results show that a weighted mean 206Pb/238U age is 236±3 Ma for quartz diorite (sample No.T6-1) located in the western slope of the basin,that weighted mean 206Pb/238U ages are 319±1 Ma (2126 m) and 361±2 Ma (1994 m) for diorite (sample No.YC1-1) and granite (sample No.YC1-2) located in northern part of southeastern uplift of the basin,respectively,and that weighted mean 206Pb/238U ages are 161±5 Ma,165±2 Ma,165±1 Ma and 161±4 Ma for samples Q2-1,SN121,SN122,and SN72 granitoids located in southern part of southeastern uplift of the basin,respectively. The statistical results of ages suggest that the middle Jurassic granitoids con-stitute the main part of basement granitoids,and that the Hercynian and Indo-Sino magmatisms also occur in the basin basement. It is implied that the Songliao basin should be a rift one formed in the intracontinent or active continental margin settings in the late Mesozoic after the Middle Jurassic orogeny took place. | GAO FuHong XU WenLiang YANG DeBin PEI FuPing LIU XiaoMing HU ZhaoChu | 2007 | Science China Earth Sciences2007，50，7： | 31 |
| 8 | Chronology and Geochemistry of Mesozoic Volcanic Rocks in the Linjiang Area,Jilin Province and their Tectonic Implications显示文摘锆石 U-Pb 年龄和 geochemical 分析结果在 Linjiang 区域为 Naozhigou, Ergulazi,和 Sidaogou 形成的暴烈的岩石被介绍,抑制岩浆来源和他们的构造背景的性质的东南的吉林省。Naozhigou 形成主要由安山岩和流纹岩和它的加权的吝啬的 206Pb/238 为 13 锆石谷物的 U 年龄是 222 ± 1 妈。Ergulazi 形成由玄武岩的安山岩,玄武岩的 trachyandesite,和安山岩组成,并且六谷物给加权的吝啬的 206Pb/ Z38 131 ± 4 妈的 U 年龄。Sidaogou 形成主要由 trachyandesite 组成并且流纹岩,和六锆石谷物产出一个加权的平均数 206Pb/238 113 ± 4 妈的 U 年龄。暴烈的岩石有 SiO 2=60.24%77.46%, MgO =0.36%1.29%( Mg #= 0.32 0.40 )为 Naozhigou 形成, SiO 2=51.60%59.32%, MgO =3.70%5.54%( Mg #= 0.50 0.60 )为 Ergulazi 形成,和 SiO 2=58.28%76.32%, MgO =0.07%1.20%( Mg #= 0.14 0.46 )为 Sidaogou 形成。踪迹元素分析结果显示这些暴烈的岩石被丰富在轻稀土元素元素( LREE )和大离子亲石元素元素( LILE )描绘,在重稀土元素元素( HREE )的相对弄空和高度回答力量元素( HFSE , Nb , Ta ,并且 Ti ),并且否定 Eu 异例。与原始披风相比,在 Linjiang 区域的中生代暴烈的岩石有相对高的起始的 87Sr/86 Sr 比率(0.7053 0.7083 ) 并且低 ɛ
Nd (t) 价值(到 2.43 的 −8.38 ) ,和显示一个食火鸟趋势。为 Naozhigou 形成的晚三叠纪的岩浆能从部分融化被导出一最新有北方中国 Craton 地下室的次要的参与的 accretional 外壳并且在 Yangtze Craton 和北方中国 Craton 的碰撞以后在前下面形成了紧张的环境。为 Ergulazi 和 Sidaogou 形成的早白垩纪暴烈的岩石能在活跃大陆人边缘与有关的构造背景下面被形成向西 Izanagi 板的 subduction。 | YU Yang XU Wenliang PEI Fuping YANG Debin ZHAO Quanguo | 2009 | Acta Geologica Sinica(English Edition)2009，83，2： | 27 |
| 9 | Observational Facts Regarding the Joint Activities of the Southwest Vortex and Plateau Vortex after Its Departure from the Tibetan Plateau显示文摘Using atmospheric observational data from 1998 to 2013,station rainfall data,TRMM(Tropical Rainfall Measuring Mission) data,as well as annual statistics for the plateau vortex and shear line,the joint activity features of sustained departure plateau vortexes(SDPVs) and southwest vortexes(SWVs) are analyzed.Some new and useful observational facts and understanding are obtained about the joint activities of the two types of vortex.The results show that:(1) The joint active period of the two vortexes is from May to August,and mostly in June and July.(2) The SDPVs of the partnership mainly originate near Zaduo,while the SWVs come from Jiulong.(3) Most of the two vortexes move in almost the same direction,moving eastward together with the low trough.The SDPVs mainly act in the area to the north of the Yangtze River,while the SWVs are situated across the Yangtze River valley.(4) The joint activity of the two vortexes often produces sustained regional heavy rainfall to the south of the Yellow River,influencing wide areas of China,and even as far as the Korean Peninsula,Japan and Vietnam.(5) Most of the two vortexes are baroclinic or cold vortexes,and they both become strengthened in terms of their joint activity.(6) When the two vortexes move over the sea,their central pressure descends and their rainfall increases,especially for SWVs.(7) The two vortexes might spin over the same area simultaneously when there are tropical cyclones in the eastern and southern seas of China,or move southward together if a tropical cyclone appears near Hainan Island. | Shuhua YU Wenliang GAO Dixiang XIAO Jun PENG | 2016 | Advances in Atmospheric Sciences2016，33，1： | 25 |
| 10 | A retrospective of knowledge graphs显示文摘 | Jihong YAN Chengyu WANG Wenliang CHENG Ming GAO Aoying ZHOU | 2018 | Frontiers of Computer Science2018，12，1： | 25 |
| 11 | Petrogenesis of Mesozoic High-Mg Diorites in Western Shandong: Evidence from Chronology and Petro-geochemistry显示文摘The high-Mg diorites, widely occurring in western Shandong, have important implications in the study of the relationship between the Mesozoic magmatism and the nature of the lithosphere and its thinning period in the eastern North China craton (NCC). The Tietonggou and Jinling intrusions are typically representatives. LA-ICP-MS zircon U-Pb dating, major and trace element and Sr-Nd isotopic compositions of the Mesozoic intrusive rocks from western Shandong, eastern China, were analyzed. The weighted mean 206Pb/ 238U ages from LA-ICP-MS zircon U-Pb dating results for early norite-diorite, late pyroxene-diorite from the Tietonggou intrusion and biotite-diorite from the Jinling intrusion are (131.4±4.9) Ma(n=15), (134.5±2.3) Ma(n=13), and (132.8±4.2) Ma(n=12), respectively, implying that they were formed in the Early Cretaceous. The weighted mean 207Pb/ 206Pb ages for round zircons from late pyroxene-diorite in the Tietonggou intrusion is (2 513±54) Ma(n=8), suggesting that the basement of the North China craton should exist in the research area. The high-Mg diorites are characterized by enrichment in MgO, Na2O, and light rare earth elements (LREE), and they are poor in heavy rare earth elements (HREE) and high field strength elements (HFSE), being similar to adakite. The existence of the mantle peridotite xenoliths with a high-Mg feature for these intrusive rocks implies that their primary magma should be derived from the upper mantle. However, Sr-Nd isotopic compositions (I sr: 0.704 75-0.707 15; ε Nd(130 Ma) values: -3.95 to -13.30), depletion in HFSE, and the occurrence of Archean inherited zircons suggest that crustal materials could be involved in the derivation of the primary magma. The compositional difference between the diorites from the Tietonggou and Jinling intrusions could be attributed to those of magma sources and degrees of partial melting. The Early Cretaceous high-Mg diorites are considered to have been formed by the mixed melting of the delaminated lithosphere (lithospheric mantle + crust) and asthenosphere, based on their geochemistry, the mantle-derived xenoliths, and the Early Mesozoic lithospheric evolutionary history of the eastern North China craton. | Yang Chenghai Xu Wenliang Yang Debin Liu Changchun Liu Xiaoming Hu Zhaochu | 2005 | Journal of China University of Geosciences2005，16，4： | 24 |
| 12 | Petrogenesis of Shangyu gabbro-diorites in western Shandong:Geochronological and geochemical evidence显示文摘Chronology and geochemistry of the Shangyu gabbro-diorite in western Shandong were studied to understand their petrogenesis and the nature of the Mesozoic lithospheric mantle. The Shangyu intru-sion is mainly composed of a suite of gabbro-diorite. Zircons from the intrusion display eu-hedral-subhedral in shape and have high Th/U ratios (1.23―2.87), implying their magmatic origin. LA-ICP-MS zircon U-Pb dating results for two samples indicate that they were formed in the Early Cre-taceous, yielding weighted mean 206Pb/238U ages of 129±1Ma and 134±2Ma, respectively. Except for early cumulate such as sample QT-19, their SiO2 and MgO contents range from 50.12% to 56.37% and from 3.52% to 6.37%, respectively. Moreover, the gabbro-diorites are characterized by high Mg# (0.54―0.63), enrichment in Na (Na2O/K2O ratios more than 1), Cr (73×10-6―217×10-6) and Ni (34×10-6―241×10-6), and intensive enrichments in light rare earth elements (LREEs) and large ion lithophile elements (LILEs) and depletion in high field strength elements (HFSEs). Their initial 87Sr/86Sr ratios and ε Nd(t) values range from 0.70962 to 0.71081 and from-16.60 to-13.04, respectively. Taken together with the Early Creta-ceous high-Mg diorites and the mantle xenoliths from the Tietonggou and Jinling as well as basalts from the Fangcheng and Feixian, it is suggested that the primary magma for the Shangyu gab-bro-diorites should be derived from the enriched lithospheric mantle intensively modified by conti-nental crust. The Sr-Nd-Pb isotopic compositions for the Early Cretaceous high-Mg diorites in western Shandong display a trend of spatial variations, i.e., initial 87Sr/86Sr, 207Pb/204Pb and 208Pb/204Pb ratios de-creasing and ε Nd(t) values increasing from southeast to northwest in western Shandong, which is con-sistent with the tectonic model that the Yangtze Craton subducted beneath the North China Craton oriented in north-west direction in the Early Mesozoic. | YANG ChengHai XU WenLiang YANG DeBin WANG Wei WANG WeiDe LIU JinMin | 2008 | Science China Earth Sciences2008，51，4： | 24 |
| 13 | Discovery of dunite and pyroxenite xenoliths in Mesozoic diorite at Jinling,western Shandong and its significance显示文摘Abundant deeply-derived xenoliths are discovered in a Mesozoic diorite at Jinling, Zibo, western Shandong, which mainly consist of dunite and pyroxenite. The dunite can be further subdivided into two subtypes. The first type shows tabular texture and high Mg# values (93—94) in olivines. The second type is characterized by the metamorphic-deformation texture superimposed by later metasomatism and relatively low olivine Mg# values (86—87). The mineral chemical data indicate that the former could be derived from ancient lithospheric mantle and the latter could have resulted from silica-rich melt metasomatism. The exsolution texture and the high Mg# value in clinopyroxenes, together with the rather high equilibrium temperature, imply that the pyroxenite xenoliths could be the cumulates of mantle-derived magma in the uppermost mantle or near the crust-mantle boundary in the Mesozoic. | XU Wenliang WANG Dongyan GAO Shan LIN Jingqian | 2003 | Chinese Science Bulletin2003，48，15： | 24 |
| 14 | Neoproterozoic basic magmatism in the southeast margin of North China Craton:Evidence from whole-rock geochemistry,U-Pb and Hf isotopic study of zircons from diabase swarms in the Xuzhou-Huaibei area of China显示文摘This paper presents a synthetic U-Pb and Hf isotopic study of zircons and a whole-rock geochemical study on diabase swarms that were emplaced into the Proterozoic formations in the Xuzhou-Huaibei area,the southeast margin of North China Craton.Zircons from the diabase dykes display weak oscillatory zoning in the cathodoluminescence(CL) images and show high Th/U ratios(0.91-6.90),both of which are typical of a magmatic origin.The SHRIMP and Q-ICP-MS U-Pb zircon dating results indicate that the diabase swarms were emplaced at ca.890 Ma.Hf isotopic analysis on these zircons gives Hf(t) values ranging from 2.26 to 14.74 and Hf model age t DM1 and t DM2 ranging from 843 to 1321 Ma and from 808 to 1779 Ma,respectively.Geochemically,the diabase swarms are characterized by a relative enrichment in LREE and LILE(Rb,Ba and La),a comparative enrichment in Cr and Ni,but a slight depletement in HFSE(Th,Nb,Ta,Zr and Hf).They are plotted in the within-plate tholeiite series on the tectonic discrimination diagrams.Taken together,these geochemical and isotopic data suggest that the primary magmas to form the diabase dykes in the Xuzhou-Huaibei area could have been derived from a transitional mantle in the Mesoproterozoic,and were most probably emplaced under a continental margin extensional setting at ca.890 Ma.The results of this study demonstrate that the Neoproterozoic(800-900 Ma)magmatism was not restricted to the Yangtze Block,but also occurred at the southeast margin of the North China Craton. | WANG QingHai YANG DeBin XU WenLiang | 2012 | Science China Earth Sciences2012，55，9： | 23 |
| 15 | Cardiotoxicity of 5-fluorouracil and capecitabine in Chinese patients: a prospective study显示文摘Background:5-Fluorouracil(5-FU)and capecitabine-associated cardiotoxicity ranging from asymptomatic electro-cardiography(ECG)abnormalities to severe myocardial infarction has been reported in a number of studies,but such cardiotoxicity in Chinese patients with malignant diseases has not been investigated to date.In the present study,we aimed to prospectively evaluate the incidence rates and clinical manifestations of 5-FU-and capecitabine-associated cardiotoxicity in cancer patients recruited from multiple centers in China.Methods:Among the 527 patients who completed the study,196 received 5-FU-based chemotherapy and 331 received capecitabine-based chemotherapy as either first-line or adjuvant therapy.Adverse events were reported during the treatment and up to 28 days of follow-up.Outcome measures included ECG,myocardial enzymes,cardiac troponin,brain natriuretic peptide and echocardiography.Univariate analysis and logistic regression were performed for subgroup analysis and identification of significant independent variables that are associated with cardiotoxicity of both agents.Results:In total,161 of 527 patients(30.6%)experienced cardiotoxicity.The incidence rate of cardiotoxicity was 33.8%(112/331)in the capecitabine group,which was significantly higher than the rate of 25%(49/196)in the 5-FU group(P=0.0042).110/527 patients(20.9%)suffered arrhythmia,105/527(19.9%)developed ischemic changes,while only 20/527 patients(3.8%)presented heart failure and 6/527 patients(1.1%)had myocardial infarction.Pre-existing cardiac disease,hypertension,capecitabine-based chemotherapy and duration of treatment were identified as sig-nificant risk factors associated with cardiotoxicity.The odds ratio were 15.7(prior history of cardiac disease versus no history),1.86(capecitabine versus 5-FU),1.06(5-8 versus 1-4 chemotherapy cycles)and 1.58(hypertension versus no hypertension),respectively.Conclusions:Cardiotoxicity induced by fluoropyrimidines in the Chinese population may be underestimated in clini-cal practice.Close monitoring of patients is recommended,especially for those patients at high risk for cardiotoxicity.Possible risk factors are duration of treatment,capecitabine-based chemotherapy,pre-existing cardiac diseases and hypertension.Trial registration This study was initiated on January 22,2014 and has been retrospectively registered with the registra-tion number ChiCTR1800015434 . | Jianjun Peng Chao Dong Chang Wang Weihua Li Hao Yu Min Zhang Qun Zhao Bo Zhu Jun Zhang Wenliang Li Fenghua Wang Qiong Wu Wenhao Zhou Ying Yuan Meng Qiu Gong Chen | 2018 | Cancer Communications2018，38，1： | 23 |
| 16 | Permian Tectonic Evolution in Southwestern Khanka Massif:Evidence from Zircon U-Pb Chronology,Hf isotope and Geochemistry of Gabbro and Diorite显示文摘激光脱离诱导地联合的血浆团 spectrometry (LA-ICP-MS ) 锆石 U-Pb 在 Hunchun 区域为二叠的斑粝岩和闪长岩标明日期和 geochemical 数据被介绍在学习区域抑制地区性的构造进化。从斑粝岩和闪长岩的锆石在形状是 euhedral 半形的并且象高 Th/U 比率(0.261.22 ) 一样显示好规模的摆动的 zoning,暗示他们的 magmatic 起源。标明日期的结果显示斑粝岩和闪长岩形成了在早二叠(在东南中国的 282inces 通常被叫作 Wan-Zhe-Gan 差错地区。地质上,这个地区由各种各样的年龄和取向的几条地区性的差错带组成。我们基于领域调查把差错分成了四个年龄组。Neoproterozoic 差错向东北正在罢工。他们从东北江西省开始并且延长对在安徽省的 Fuchuan 向东北,东北 Jiangxi-Fuchuan ophiolite 带的一样的地点。可能作为一条边界在 Neoproterozoic 期间扮演的差错与 m 指责一个盘子或块缝术的地区 ???? | CAO Huahua XU Wenliang PEI Fuping ZHANG Xingzhou | 2011 | Acta Geologica Sinica(English Edition)2011，85，6： | 20 |
| 17 | Polychlorinated biphenyls in the atmosphere of Taizhou,a major e-waste dismantling area in China显示文摘PM2.5,total suspended particles(TSP) and gas phase samples were collected at two sites of Taizhou,a major e-waste dismantling area in China.Concentrations,seasonal variations,congener profiles,gas-particle partitioning and size distribution of the atmospheric polychlorinated biphenyls(PCBs) were studied to assess the current state of atmospheric PCBs after the phase out of massive historical dismantling of PCBs containing e-wastes.The average 38PCBs concentration in the ambient air(TSP plus gas phase) near the e-waste dismantling area was(12,407 ± 9592) pg/m3 in winter,which was substantially lower than that found one decade ago.However,the atmospheric PCBs level near the e-waste dismantling area was 54 times of the reference urban site,indicating that the impact of the historical dismantling of PCBs containing e-wastes was still significant.Tri-Penta-CBs were dominant homologues,consisting with their dominant global production.Size distribution of particle-bound PCBs showed that higher chlorinated CBs tended to partition more to the fine particles,facilitating its long range air transportation. | Wenliang Han Jialiang Feng Zeping Gu Minghong Wu Guoying Sheng Jiamo Fu | 2010 | Journal of Environmental Sciences2010，22，4： | 18 |
| 18 | Geochronology and Geochemistry of Middle–Late Ordovician Granites and Gabbros in the Erguna Region,NE China:Implications for the Tectonic Evolution of the Erguna Massif显示文摘Zircon U-Pb ages, Hf isotope data and whole-rock major and trace element data for the Middle to Late Ordovician gabbros and granites in the Erguna Massif, NE China were presented in this paper. The petrogenesis of these rocks and the Early Paleozoic tectonic evolution of the massif were discussed. Zircons from the granites and gabbros are of magmatic origin based on their cathodoluminescence(CL) images. The 206Pb/238 U ages obtained from 20 spots on zircons from the granites range from 446±9 to 464±10 Ma, yielding a weighted mean age of 455±10 Ma; and 16 spots on zircons from the gabbros range from 465±10 to 466±7 Ma, yielding a weighted mean age of 465±2 Ma. Chemically, the Late Ordovician granites in the Erguna Massif are weakly peraluminous and similar to A-type granites. The granites and gabbros are all enriched in light rare earth elements and large ion lithophile elements(e.g., Rb, K), and depleted in heavy rare earth elements and high field strength elements(e.g., Nb, Ta, and Ti); they all exhibit marked negative Eu anomalies. Their zircon εHf(t) values range mainly from +1.86 to +6.21(for the granites) and +1.39 to +3.89(for the gabbros), except for one spot with a value of-0.27(for a gabbro). The TDM1 ages for the gabbros and TDM2 ages for the granites vary from 928 to 1 091 Ma and from 1 287 to 1 675 Ma, respectively. It is concluded that the primary magma of the granites could have been derived by partial melting of Mesoproterozoic newly accreted crustal material, whereas the primary magma of the gabbros originated by partial melting of a depleted mantle wedge that had been metasomatized by fluids derived from a subducted slab. These Middle–Late Ordovician granites and gabbros constitute a typical bimodal igneous rock association, implying an extensional environment that was probably related to the post-collisional development of the Erguna and Xing'an massifs in the early Early Paleozoic. | Shuo Zhao Wenliang Xu Wei Wang Jie Tang Yihan Zhang | 2014 | Journal of Earth Science2014，25，5： | 17 |
| 19 | Chronology and Geochemistry of Volcanic Rocks in the Cretaceous Suifenhe Formation in Eastern Heilongjiang,China显示文摘摘要:在在东方 Heilongjiang 省的 Suifenhe 形成的暴烈的岩石的锆石 U-Pb 年龄和 geochemical 数据被报导,并且他们的 petrogenesis 在这份报纸被讨论。Suifenhe 形成主要由暗岩,安山岩,和 dacite 组成。从安山岩和 dacite 的锆石是在形状的 euhedral 并且与高 Th/U 比率(0.18-0.57 ) 显示出典型摆动的 zoning,暗示它的 magmatic 起源。诱导地由激光脱离标明日期结果的锆石 U-Pb 联合了血浆团分光计(LA-ICP-MS ) 显示从安山岩的锆石的 206Pb/238U 年龄在 105106 妈以内变化,产出 105.5 | JI Weiqiang XU Wenliang YANG Debin PEI Fuping JIN Ke LIU Xiaoming | 2007 | Acta Geologica Sinica(English Edition)2007，81，2： | 16 |
| 20 | Spatial patterns of ecosystem vulnerability changes during 2001–2011 in the three-river source region of the Qinghai-Tibetan Plateau, China显示文摘The three-river source region(TRSR, including Yangtze, Yellow and Lancang rivers), located in the Qinghai-Tibetan Plateau, China, is a typical alpine zone with apparent ecosystem vulnerability and sensitivity. In this paper, we introduced many interdisciplinary factors, such as landscape pattern indices(Shannon diversity index and Shannon evenness index) and extreme climate factors(number of extreme high temperature days, number of extreme low temperature days, and number of extreme precipitation days), to establish a new model for evaluating the spatial patterns of ecosystem vulnerability changes in the TRSR. The change intensity(CI) of ecosystem vulnerability was also analyzed. The results showed that the established evaluation model was effective and the ecosystem vulnerability in the whole study area was intensive. During the study period of 2001–2011, there was a slight degradation in the eco-environmental quality. The Yellow River source region had the best eco-environmental quality, while the Yangtze River source region had the worst one. In addition, the zones dominated by deserts were the most severely deteriorated areas and the eco-environmental quality of the zones occupied by evergreen coniferous forests showed a better change. Furthermore, the larger the change rates of the climate factors(accumulative temperature of ≥10°C and annual average precipitation) are, the more intensive the CI of ecosystem vulnerability is. This study would provide a scientific basis for the eco-environmental protection and restoration in the TRSR. | GUO Bing ZHOU Yi ZHU Jinfeng LIU Wenliang WANG Futao WANG Litao YAN Fuli WANG Feng YANG Guang LUO Wei JIANG Lin | 2016 | Journal of Arid Land2016，8，1： | 16 |
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