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| 1 | Laser produced electromagnetic pulses: generation, detection and mitigation显示文摘This paper provides an up-to-date review of the problems related to the generation,detection and mitigation of strong electromagnetic pulses created in the interaction of high-power,high-energy laser pulses with different types of solid targets.It includes new experimental data obtained independently at several international laboratories.The mechanisms of electromagnetic field generation are analyzed and considered as a function of the intensity and the spectral range of emissions they produce.The major emphasis is put on the GHz frequency domain,which is the most damaging for electronics and may have important applications.The physics of electromagnetic emissions in other spectral domains,in particular THz and MHz,is also discussed.The theoretical models and numerical simulations are compared with the results of experimental measurements,with special attention to the methodology of measurements and complementary diagnostics.Understanding the underlying physical processes is the basis for developing techniques to mitigate the electromagnetic threat and to harness electromagnetic emissions,which may have promising applications. | Fabrizio Consoli Vladimir TTikhonchuk Matthieu Bardon Philip Bradford David CCarroll Jakub Cikhardt Mattia Cipriani Robert JClarke Thomas ECowan Colin NDanson Riccardo De Angelis Massimo De Marco Jean-Luc Dubois Bertr Etchessahar Alejro Laso Garcia David IHillier Ales Honsa Weiman Jiang Viliam Kmetik Josef Krása Yutong Li FredériéLubrano Paul McKenna Josefine Metzkes-Ng Alexre Poyé Irene Prencipe Piotr Ra¸czka Rol ASmith Roman Vrana Nigel CWoolsey Egle Zemaityte Yihang Zhang Zhe Zhang Bernhard Zielbauer David Neely | 2020 | High Power Laser Science and Engineering2020,8,2: | 3 |
| 2 | Arylamine N-acetyltransferase 2 genotype-dependent N-acetylation of isoniazid in cryopreserved human hepatocytes显示文摘Cryopreserved human hepatocytes were used to investigate the role of arylamine Nacetyltransferase 2(NAT2; EC 2.3.1.5) polymorphism on the N-acetylation of isoniazid(INH). NAT2 genotype was determined by Taqman allelic discrimination assay and INH N-acetylation was measured by high performance liquid chromatography. INH N-acetylation rates in vitro exhibited a robust and highly significant(P o0.005) NAT2 phenotype-dependent metabolism. N-acetylation rates in situ were INH concentration-and time-dependent. Following incubation for 24 h with 12.5 or 100 mmol/L INH, acetylINH concentrations varied significantly(P = 0.0023 and P = 0.0002) across cryopreserved human hepatocytes samples from rapid, intermediate, and slow acetylators, respectively. The clear association between NAT2 genotype and phenotype supports use of NAT2 genotype to guide INH dosing strategies in the treatment and prevention of tuberculosis. | Mark A.Doll Raúl A.Salazar-González Srineil Bodduluri David W.Hein | 2017 | Acta Pharmaceutica Sinica B2017,7,4: | 3 |
| 3 | Evaluation of 5 versus 10 granulocyteaphaeresis sessions in steroid-dependent ulcerative colitis: A pilot, prospective, multicenter, randomized study显示文摘瞄准:与活跃类固醇依赖者 ulcerative 在病人与 10 个 granulocyteaphaeresis 会议相比评估 5 的功效。方法:在这名飞行员,未来,多集中使随机化的试用,有中等活跃的类固醇的 20 个病人 -- 依赖 ulcerative 被使随机化到 5 或 10 个 granulocyteaphaeresis 会议。主要目的是在 wk 的临床的宽恕 17。第二等的措施包括了内视镜的宽恕和类固醇消费。结果:九个病人被使随机化到 5 个 granulocyteaphaeresis 会议(组 1 ) 和 11 个病人到 10 个 granulocyteaphaeresis 会议(组 2 ) 。在 wk 17,在在组 2 的组 1 病人和 45.45% 的 37.5% 病人在临床的宽恕。临床的宽恕被内视镜的宽恕在所有情况中伴随。完成宽恕的百分之 86 个病人在 wk 是没有类固醇的 17。每日的类固醇要求在组 2 是显著地更低的。病人的 89% 在一年后续期间留在宽恕。一个严肃的不利事件不与学习治疗有关,被报导。结论:Granulocyteaphaeresis 为类固醇依赖者 ulcerative 的治疗安全、有效。在这张人口,增加 aphaeresis 会议的数字没与更高的宽恕率被联系,但是负担得起重要类固醇圆材效果。 | Elena Ricart Maria Esteve Montserrat Andreu Francesc Casellas David Monfort Miquel Sans Natalia Oudovenko Raúl Lafuente Julián Panés | 2007 | World Journal of Gastroenterology2007,13,15: | 3 |
| 4 | Prevalence and factors associated with failure of liver stiffness measurement using FibroScan in a prospective study of 2114 examinations显示文摘 | Juliette Foucher Laurent Castéra Pierre-Henri Bernard Xavier Adhoute David Laharie Julien Bertet Patrice Couzigou Victor de Lédinghen | 2006 | European Journal of Gastroenterology & Hepatology2006,,4: | 3 |
| 5 | International study group on rectal cancer regression grading: interobserver variability with commonly used regression grading systems显示文摘 | Runjan Chetty Pelvender Gill Dhirendra Govender Adrian Bateman Hee Jin Chang Vikram Deshpande David Driman Marisa Gomez Godman Greywoode Eleanor Jaynes C. Soon Lee Michael Locketz Corwyn Rowsell Anne Rullier Stefano Serra Neil Shepherd Eva Szentgyorgyi Ra | 2012 | Human Pathology2012,,11: | 2 |
| 6 | Radiologic features of eosinophilic granuloma of bone显示文摘 | David R Oria RA KumarR | 1989 | AJR1989,153,5: | 1 |
| 7 | ACCP/AHA guidelines for coronary artery bypass graft surgery显示文摘 | Eagle KA Guyton RA David R | 1999 | J Am Coll Cardiol1999,34,: | 1 |
| 8 | Myocardial bridge显示文摘 | Jorge RA Joerg H David RH Jr | 2005 | European Heart J2005,26,12: | 1 |
| 9 | Development and validation of a method for analysis of 'dioxin-like' PCBs in environmental samples from the steel industry显示文摘 | David RA Nicholas O | 2004 | Chemosphere2004,54,: | 1 |
| 10 | Binding of proteins to CNBr-activated sepharose 4B显示文摘 | David GS Chino TH Reisfeld RA | 1974 | FEBS Lett1974,43,3: | 1 |
| 11 | 2008 focused update incorporated into the ACC/AHA 2006 guidelines for the management of patients with vascular heart disease显示文摘 | Nishimura RA Carabello BA David PF | 2008 | J Am Coll Cardiol2008,52,13: | 1 |
| 12 | Vascular involvement in pancreatic adenocarcinoma: reassessment by thin-section CT显示文摘 | Loyer EM David CL Dubrow RA | 1996 | Abdom Imaging1996,21,: | 1 |
| 13 | Potentially respectable pancreatic ductal adenocarcinoma and perampullary carcinoma:analysis of enhancement characteristics on biphasic and triphasic helical CT显示文摘 | Dubrow RA Houston CL David SK | 1997 | RSNA1997,205,: | 1 |
| 14 | Vascular Involvement in Pancreatic Adenocarcinoma: Reassessment by Thin-section CT显示文摘 | David CL Dubrow RA | 1996 | Abdom Imaging1996,21,3: | 1 |
| 15 | Vascular involvement in pancreatic adenocarcinoma: reassessment by thinsection CT 显示文摘 | Loyer EM David CL Dubrow RA | 1996 | Abdom Imaging1996,21,3: | 1 |
| 16 | Vascular involvement in pancreaticcarcinoma:reassessment by thin-section CT显示文摘 | Loyer EM David CL Dubrow RA | 1996 | Abdom Imaging1996,207,: | 1 |
| 17 | Vascular in- volvement in pancreatic adenocarcinoma: reassessment by thin-section CT 显示文摘 | Loyer EM David CL Dubrow RA | 1996 | A JR1996,21,3: | 1 |
| 18 | Diversity, Endemism and Conservation of Ferns(Polypodiales) in the Mexican Mountain Component显示文摘We analyzed the distributional patterns of95 selected species of leptosporangiate ferns inhabiting the Mexican Mountain Component, using grid-cells of one geographical degree as unit areas,applying endemism indices and richness and beta diversity analyses.Distributional data were obtained from several herbaria and specialized literature.Five grid-cells appear to be important for fern species richness, as they contain 35 to 49 species.These gridcells are located in the Sierra Madre Oriental(SMO),Trans-Mexican Volcanic Belt(TMVB) and the Sierra Madre del Sur(SMS).Mean richness by latitudinal belts of one degree showed that the belts with highest values are related to the TMVB and SMS.A total of 13grid-cells were recognized as important from theperspective of endemism; most of them are located also in the SMO, TMVB and SMS.The richest gridcells coincided with one of the main centres of endemism for ferns obtained in this study, located in the convergence of the southern part of the SMO, the eastern portion of the TMVB and the northern part of the SMS, reflecting the high humidity existing on the mountain slopes facing the Gulf of Mexico.Some important grid-cells recognized from richness and endemism analyses coincide with Mexican Natural Protected Areas.The beta diversity analysis showed a low degree of similarity among grid-cells, implying a high species replacement, as the result of environmental heterogeneity occurring in the Mexican mountain systems.On the other hand, the spatial analysis suggested a pattern of phytogeographical regionalization comprising twomain areas: the Mexican Transition Zone and the Mexican Central Plateau.Ferns play an important role in the Mexican biodiversity and contributing to the beta diversity of Mexico. | SANGINéS-FRANCO Celia LUNA-VEGA Isolda CONTRERAS-MEDINA Raúl ESPINOSA David TEJERO-DíEZ José Daniel RIVAS Gerardo | 2015 | Journal of Mountain Science2015,12,4: | 1 |
| 19 | Vascular involvement in pancreatic adenocarcinoma:reassessment by thin-section CT显示文摘 | Loyer EM David CL Dubrow RA | 1996 | Abdom Imaging1996,21,3: | 1 |
| 20 | Association of common polymorphisms in inflammatory genes with risk of developing cancers of the upper aerodigestive tract显示文摘 | Daniele Campa Mia Hashibe David Zaridze Neonila Szeszenia-Dabrowska Ioan Nicolae Mates Vladimir Janout Ivana Holcatova Eleonóra Fabiánová Valérie Gaborieau Rayjean J. Hung Paolo Boffetta Paul Brennan Federico Canzian | 2007 | Cancer Causes & Control2007,,4: | 1 |