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| 1 | 放化疗联合局部切除在直肠癌器官保留中的应用:GRECCAR2随机对照试验的5年结果显示文摘背景:GRECCAR2是第一个对低位直肠癌局部切除(local ex-cision,LE)和全直肠系膜切除(total mesorectal excision,TME)进行比较的多中心随机试验。3年的随访发现了可喜的肿瘤学结果,但仍需要更长时间的随访来证实。在这项研究中,我们的目标是报告5年的肿瘤学结果,包括局部复发、转移性疾病和生存率。 | 佟伟华 RULLIER E VENDRELY V ASSELINEAU J | 2020 | 结直肠肛门外科2020，26，3： | 11 |
| 2 | International study group on rectal cancer regression grading: interobserver variability with commonly used regression grading systems显示文摘 | Runjan Chetty Pelvender Gill Dhirendra Govender Adrian Bateman Hee Jin Chang Vikram Deshpande David Driman Marisa Gomez Godman Greywoode Eleanor Jaynes C. Soon Lee Michael Locketz Corwyn Rowsell Anne Rullier Stefano Serra Neil Shepherd Eva Szentgyorgyi Ra | 2012 | Human Pathology2012，，11： | 2 |
| 3 | Laparoscopic Versus Open Surgery for Rectal Cancer: Long-Term Oncologic Results显示文摘 | Christophe Laurent Fabien Leblanc Philippe Wütrich Mathieu Scheffler Eric Rullier | 2009 | Annals of Surgery2009，，： | 2 |
| 4 | Liver myofibroblasts activate protein C and respond to activated protein C显示文摘AIM:To study the protein C activation system in human liver myofibroblasts,and the effects of activated protein C(APC)on these cells.METHODS:Human liver myofibroblasts were obtained by outgrowth.Expression of protease activated receptor 1(PAR-1),endothelial protein C receptor(EPCR) and thrombomodulin(TM)was analyzed by flow cytometry.Extracellular signal-regulated kinase(ERK)1/2 activation was assessed by Western blotting using anti-phospho-ERK antibodies.Collagen synthesis was studied with real-time reverse transcription-polymerase chain reaction(RT-PCR).Activation of protein C was studied by incubating liver myofibroblasts with zymogen protein C in the presence of thrombin and detecting the generation of APC with a colorimetric assay using a peptide substrate. RESULTS:Primary cultures of human liver myofibroblasts expressed EPCR on their surface,together with PAR-1 and TM.This receptor system was functional since exposure of myofibroblasts to APC inducedERK1/2 phosphorylation in a dose-and time-dependent manner.Furthermore,APC significantly upregulated the expression of collagen mRNA,as shown by real-time RT-PCR.Collagen upregulation was controlled through the ERK pathway as it was inhibited when using the mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor PD98059.Finally,using a cell-based colorimetric assay,we showed that intact myofibroblasts converted protein C into APC in the presence of thrombin.CONCLUSION:These data suggest that APC is a new modulator of liver myofibroblast activity and contributes to the pathophysiology of chronic liver diseases. | Jennifer Gillibert-Duplantier Anne Rullier Véronique Neaud Walter Kisiel Jean Rosenbaum | 2010 | World Journal of Gastroenterology2010，16，2： | 2 |
| 5 | Sphincter-saving resec- tion for all rectal carcinomas: the end of the 2 cm distal rule 显示文摘 | Rullier E Laurent C Bretagnol F | 2005 | Ann Surg2005，241，3： | 1 |
| 6 | Risk factors for anastomotic leakage after resection of rectal cancer 显示文摘 | Rullier E Laurent C Garrelon JL | 1998 | Br J Sung1998，85，3： | 1 |
| 7 | A multi-centre pathologist survey on pathological processing and regression grading of colorectal cancer resection specimens treated by neoadjuvant chemoradiation显示文摘 | Runjan Chetty Pelvender Gill Dhirendra Govender Adrian Bateman Hee Jin Chang David Driman Fraser Duthie Marisa Gomez Eleanor Jaynes Cheok Soon Lee Michael Locketz Claudia Mescoli Corwyn Rowsell Anne Rullier Stefano Serra Neil Shepherd Eva Szentgyorgyi Raj | 2012 | Virchows Archiv2012，，2： | 1 |
| 8 | Loop ileostomy versus loop colostomy for defunctioning low anastomoses during rectal cancer surgery显示文摘 | Rullier E Tous NL Laurent C | 2001 | World J Surg2001，25，3： | 1 |
| 9 | Efforts to improve local con- trol in rectal cancer compromise survival by the potential morbidity of optimal mesoreetal excision显示文摘 | Laurent C Nobili S Rullier A | 2006 | J Am Coll Surg2006，203，： | 1 |
| 10 | Efficacy of Sacral Nerve Stimulation for Fecal Incontinence: Results of a Multicenter Double-Blind Crossover Study显示文摘 | Anne-Marie Leroi Yann Parc Paul-Antoine Lehur Fran?ois Mion Xavier Barth Eric Rullier Laurent Bresler Guillaume Portier Francis Michot | 2005 | Annals of Surgery2005，，5： | 1 |
| 11 | Low rectal cancer:classifica- tion and standardization of surgery 显示文摘 | Rullier E Denost Q Vendrely F | 2013 | Dis Colon Rectum2013，56，5： | 1 |
| 12 | Sphincter-saving resection for all rectal carcinomas:the end of the 2-cm distal rule显示文摘 | Rullier E Laurent C Bretagnol F | 2005 | Ann Surg2005，241，3： | 1 |
| 13 | Preoperative radiochemotherapy and sphincter saving resection for T3 carcinomas of the lower third of the rectum显示文摘 | Rullier E Goffre B Bonnel C | 2001 | Ann Surg2001，234，5： | 1 |
| 14 | Low rectal cancer: classification and standardization of surgery显示文摘 | Rullier E Denost Q Vendrely V | 2013 | Dis Colon Rectum2013，56，5： | 1 |
| 15 | Intersphincterie resection for patientstII very low rectal cancer! all active approach to avoid a pemument eolostomy 显示文摘 | Rullier E Zebib F Laurent C | 2004 | Dis Colon Rectum2004，47，： | 1 |
| 16 | Comparison of functional results and quality of life between inter- sphincteric resection and conventional coloanal anasto- mosis for low rectal cancer显示文摘 | Bretagnol F Rullier E Laurent C | 2004 | Dis Colon Rectum2004，47，6： | 1 |
| 17 | Risk factors for anaslomotic leakage after resection of rectal cancer显示文摘 | Rullier E Laurent C Garrelon JL | 1998 | Br J $urg1998，85，3： | 1 |
| 18 | Laparoscopic intersphincteric resection with coloplasty and coloanal anastomos is for mid and low rectal cancer显示文摘 | Rullier E Sacunha A Couderc P | 2005 | Br J Surg2005，241，3： | 1 |
| 19 | Impact of Tumor Response on Survival After Radiochemotherapy in Locally Advanced Rectal Carcinoma显示文摘 | Anne Rullier Christophe Laurent Maylis Capdepont Véronique Vendrely Paulette Bioulac-Sage Eric Rullier | 2010 | The American Journal of Surgical Pathology2010，，4： | 1 |
| 20 | Comparison of functional results and quality of life between intersphincteric resection and conventional coloanal anastomosis for low rectal cancer显示文摘 | Bretagnol F Rullier E Laurent C | 2004 | Dis Colon Rectum2004，47，6： | 1 |
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