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| 1 | 中国妇女妊娠前后单纯服用叶酸对神经管畸形的预防效果显示文摘目的 评价妇女在妊娠前后服用单纯 40 0 μg叶酸增补剂对胎 /婴儿神经管畸形 (NTDs)的预防效果。方法 1993~ 1995年在中国北方的NTDs高发地区和南方的NTDs低发地区妇女增补叶酸的推广项目中 ,共募集从孕前或孕后任何时间开始服药的妇女 130 142名 ,未服药的妇女 1176 89名 ;设计的服药方法从婚检时开始到孕满 3个月为止 ,每天服用单纯叶酸片 40 0 μg ;最后对妇女的分娩结局进行监测并进行预防效果的对比评价研究。结果 服药组妇女生育的胎婴儿中共发现 10 2例NTDs ,对照组胎婴儿中共发现 173例NTDs。末次月经前募集的未服药妇女在孕 2 0周以后分娩的胎婴中NTDs发生率 ,北方为 4 8‰ (16 / 3 318) ,南方为 1 0‰ (2 8/ 2 82 6 5 ) ,而妊娠前后服药妇女组则分别为1 0‰ (13/ 13 0 12 )和 0 6‰ (34/ 5 86 38)。与末次月经前募集的未服药妇女组相比 ,北方服药妇女NTDs发生率明显降低 ,其中依从性大于 80 %的服药组妇女预防率达 85 % (95 %CI为 6 2 %~ 94% ) ,南方地区服叶酸的预防率为 41% (95 %CI为 3 %~ 6 4% )。结论 妇女在妊娠前后每天服用单纯叶酸 40 0 | 李竹 RobertJ Berry 李松 J David Erickson 王红 Cynthia A Moore 赵平 Joseph Mulinare 洪世欣 Lee-Yang C Wong 呼和牧人 Jacqueline Gindler 郝玲 Adolfo Correa 朱慧萍 Elaine Gunter | 2000 | 中华医学杂志2000，80，7： | 185 |
| 2 | Oxidative stress in humans following the Pringle manoeuvre显示文摘BACKGROUND: Oxidative stress is induced in the liver by application of the Pringle manoeuvre. Malondialdehyde is a carbonyl compound formed during lipid peroxidation and prostaglandin biosynthesis, which combines with DNA to form a number of adducts. Among them is the DNA ad-duct; 3-(2-deoxybeta-dierythropentafuranosyl) pyr [1,2-alpha]-purin-10(3H) one or M1G. This study was undertaken to determine the suitability of M1G as a novel marker of ischemia-reperfusion injury in the liver and its correlation with both the length of Pringle clamp application and the overall length of the operation. METHODS: Normal and colorectal liver metastatic tissues were obtained in 12 patients before and after application of the Pringle manoeuvre. All samples were snap-frozen in liquid nitrogen at -80 ℃. DNA was extracted and M1G quantification was performed by immunoslotblot analysis. RESULTS: M1G levels in normal liver tissue were 4.0 + 1.0 per 107 nucleotides before the Pringle manoeuvre and 7.4 ± 1.0 per 10 nucleotides after the Pringle manoeuvre (mean ± standard deviation) (P<0.05 by ANOVA). M1G levels in malignant liver tissue were 2.5 ±1.4 per 107 nucleotides before the Pringle manoeuvre and 6. 5 ±1.9 adducts per 10 nucleotides after the Pringle manoeuvre (P <0. 05). Ad-duct levels in normal liver tissue showed a significant correlation with cumulative period of Pringle application. CONCLUSIONS: This is the first time that the tissue levels of M1G before and after application of the Pringle manoeuvre have been studied. The results show that the Pringle manoeuvre exerts significant oxidative stress in human hepa-tocytes, which is Pringle-time dependent. The results highlight the potential for oxidative DNA adducts levels as a tool for measuring the severity of ischemia-reperfusion injury. | Giuseppe Garcea Andreas Gescher William Steward Ashley Dennison David Berry | 2006 | Hepatobiliary & Pancreatic Diseases International2006，5，2： | 4 |
| 3 | Practice Guidelines for Management of the Difficult Airway: An Updated Report by the American Society of Anesthesiologists Task Force on Management of the Difficult Airway显示文摘 | Jeffrey L. Apfelbaum Carin A. Hagberg Robert A. Caplan Casey D. Blitt Richard T. Connis David G. Nickinovich Carin A. Hagberg Robert A. Caplan Jonathan L. Benumof Frederic A. Berry Casey D. Blitt Robert H. Bode Frederick W. Cheney Richard T. Connis Orin F | 2013 | Anesthesiology2013，，2： | 4 |
| 4 | Significance of the balance between intracellular glutathione and polyethylene glycol for successful release of small interfering RNA from gold nanoparticles显示文摘为特定的基因 silencing 的小介入 RNA (siRNAs ) 的治疗学的诺言依赖于到细胞质的功能的 siRNAs 的成功的交货。他们到一个确定的交货平台的变化形式例如金 nanoparticles,为治疗疾病并且推进我们细胞的过程的理解提供巨大的潜力。他们的成功或失败依赖于两个进房间和功能的 siRNA 的随后的细胞内部的版本的 nanoparticles 的举起。在这研究,利用金 nanoparticle 对 C-MYC 的 调停siRNA 的交货,我们试图决定我们是否能完成在一个癌症房间击倒与细胞内部的谷胱甘肽的底层排队,并且如果有的话,聚乙烯乙二醇(木钉)决定影响 ligand 密度在上击倒,考虑到决定最佳的 nanoparticle 设计完成 C-MYC 击倒。我们表明那,不管木钉密度,在有相对低的谷胱甘肽层次的房间击倒能被完成,以及为在细胞内部的环境的劈开的 siRNA 的可获得性上的木钉的位的阻碍者的可能的效果。当击倒时,金 nanoparticle 举起经由传播电子显微镜学和集体光谱学被表明被在里面房间 westerns 和 BrdU 加入分别地在蛋白质和生理的层次(在 S 阶段的房间) 决定。 | Mark McCully Yulan Hernandez Joao Conde Pedro V. Baptista Jesus M. de la Fuente Andrew Hursthouse David Stirling Catherine C. Berry | 2015 | Nano Research2015，8，10： | 2 |
| 5 | Curcumin: The potential for efficacy in gastrointestinal diseases显示文摘 | Glen R.B. Irving Ankur Karmokar David P. Berry Karen Brown William P. Steward | 2011 | Best Practice & Research Clinical Gastroenterology2011，，4： | 2 |
| 6 | Sustainability of a non - timber forest product: effects of alternative leaf harvest practices over 6 years on yield and demography of the palm Chamaedorea radicalis显示文摘 | Bryan A Endress David L Gorchov Eric J Berry | 2006 | Forest Ecology and Management2006，234，2： | 1 |
| 7 | Synthesis of crystallization-dis- tillation hybrid separation process 显示文摘 | David A Berry Ka M Ng | 1997 | A I Ch E J1997，43，7： | 1 |
| 8 | Staging system for breast cancer: revisions for the 6th edition of the AJCC Cancer Staging Manual显示文摘 | S.Eva Singletary Craig Allred Pandora Ashley Lawrence W Bassett Donald Berry Kirby I Bland Patrick I Borgen Gary M Clark Stephen B Edge Daniel F Hayes Lorie L Hughes Robert V.P Hutter Monica Morrow David L Page Abram Recht Richard L Theriault Ann Thor Don | 2003 | Surgical Clinics of North America2003，，4： | 1 |
| 9 | Rare Earth Element Concentrations and Speciation in Alkaline Lakes from the Western USA 显示文摘 | Kevin H Johannesson W Lyons Berry David A Bird | 1994 | Geophysical Research Letters1994，21，9： | 1 |
| 10 | Improvement in Stroke Mortality in Canada and the United States, 1990 to 2002显示文摘 | Quanhe Yang Lorenzo D. Botto J David Erickson Robert J. Berry Christie Sambell Helen Johansen J M. Friedman | 2006 | Circulation2006，，10： | 1 |
| 11 | Feasibility of hybrid thoracoscopic lobectomy and en-bloc chest wall resection ? 显示文摘 | Mark F. Berry Mark W. Onaitis Betty C. Tong Stafford S. Balderson David H. Harpole Thomas A. D&apos Amico | 2012 | European Journal of Cardio-Thoracic Surgery2012，，4： | 1 |
| 12 | Rare earth element concentrations and speciation in alkaline lakes from the western USA显示文摘 | Johannesson Kevin H Berry W L Bird David A | 1994 | Geophysical Research Letters1994，21，9： | 1 |
| 13 | Platelet gel: An autologous alternative to fibrin glue with applications in oral and maxillofacial surgery显示文摘 | Dean H Whitman Ronald L Berry David M Green | 1997 | Journal of Oral and Maxillofacial Surgery1997，，11： | 1 |
| 14 | Fuel processor integrated H2S partial oxidation technology for sulfur removal in fuel cell power plants显示文摘 | Todd H Gardner David A Berry | 2002 | Fuel2002，81，17： | 1 |
| 15 | Synthesis of Crys- tallization -distallation Hybrid Separation Process 显示文摘 | David A Berry Ka M N | 1997 | A I Ch E1997，43，7： | 1 |
| 16 | Prevention of neural tube defects with folic acid in China显示文摘 | Robert J Berry Zhu Li J David Erickson | 1993 | The New England Journal of Medicine1993，341，20： | 1 |
| 17 | Delivering Energy Savings through Community - Based Organizations 显示文摘 | David Berry | 2010 | The Electricity Journal2010，，10： | 1 |
| 18 | Effect of particle shape on the spectral absorption of colloidal silver in gelatin 显示文摘 | Skillman David C Berry Chester R | 1968 | J Chem Phys1968，48，： | 1 |
| 19 | Intensity-modulated radiation therapy (IMRT) for nasopharynx cancer: Update of the Memorial Sloan-Kettering experience显示文摘 | Suzanne L. Wolden William C. Chen David G. Pfister Dennis H. Kraus Sean L. Berry Michael J. Zelefsky | 2006 | International Journal of Radiation Oncology, Biology, Physics2006，，1： | 1 |
| 20 | Systematic Review of Minimally Invasive Pancreatic Resection显示文摘 | Christopher D. Briggs Christopher D. Mann Glen R. B. Irving Christopher P. Neal Mark Peterson Iain C. Cameron David P. Berry | 2009 | Journal of Gastrointestinal Surgery2009，，6： | 1 |
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