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| 1 | The clinical impact of bacterial biofilms显示文摘Bacteria survive in nature by forming biofilms on surfaces and probably most, if not all, bacteria (and fungi) are capable of forming biofilms. A biofilm is a structured consortium of bacteria embedded in a self-produced polymer matrix consisting of polysaccharide, protein and extracellular DNA. Bacterial biofilms are resistant to antibiotics, disinfectant chemicals and to phagocytosis and other components of the innate and adaptive inflammatory defense system of the body. It is known, for example, that persistence of staphylococcal infections related to foreign bodies is due to biofilm formation. Likewise, chronic Pseudomonas aeruginosa lung infections in cystic fibrosis patients are caused by biofilm growing mucoid strains. Gradients of nutrients and oxygen exist from the top to the bottom of biofilms and the bacterial cells located in nutrient poor areas have decreased metabolic activity and increased doubling times. These more or less dormant cells are therefore responsible for some of the tolerance to antibiotics. Biofilm growth is associated with an increased level of mutations. Bacteria in biofilms communicate by means of molecules, which activates certain genes responsible for production of virulence factors and, to some extent, biofilm structure. This phenomenon is called quorum sensing and depends upon the concentration of the quorum sensing molecules in a certain niche, which depends on the number of the bacteria. Biofilms can be prevented by antibiotic prophylaxis or early aggressive antibiotic therapy and they can be treated by chronic suppressive antibiotic therapy. Promising strategies may include the use of compounds which can dissolve the biofilm matrix and quorum sensing inhibitors, which increases biofilm susceptibility to antibiotics and phagocytosis. | Niels Hoiby Oana Ciofu Helle Krogh Johansen Zhi-jun Song Claus Moser Peter Ostrup Jenser Soren Molin Michael Givskov Tim Tolker-Nieisen Thomas Bjamsholt | 2011 | International Journal of Oral Science2011，3，2： | 48 |
| 2 | 基于像元和对象分类的城区植被高分辨率遥感制图比较研究显示文摘本研究利用高空间分辨率遥感影像和LiDAR数据,参照美国USGS植被分类体系,在两种不同分类层次上,评价了基于像元和基于对象分类两种方法的城区植被覆盖专题制图效果.采用传统的基于像元监督最大似然分类时,在下层分类层次,分类总精度仅为70.5%,Kappa系数为63.5%.当在上层分类层次进行分类时,分类精度相对下层分类层次有明显提高,总精度达84%,Kappa系数为75.8%.而采用面向对象的分类方法时,在下层分类层次,分类总精度为86%,Kappa系数为82.3%.在上层分类层次,总精度达90.8%,Kappa系数为86.2%.研究结果表明,在城区两种不同植被分类层次,面向对象分类结果都取得了优于基于像元的分类结果. | 谭衢霖 STEVE Johansen | 2011 | 应用基础与工程科学学报2011，19，3： | 11 |
| 3 | 手部湿疹严重指数(HECSI):手部湿疹临床评价的评分系统在观察者间及观察者内的可靠性研究 | Held E. Skoet R. Johansen J.D. Agner T. 罗素菊 冯义国 | 2005 | 世界核心医学期刊文摘(皮肤病学分册)2005，0，7： | 8 |
| 4 | 骨科教程 膝关节内侧副韧带及内侧结构的损伤显示文摘内侧副韧带浅层及其他内侧的膝关节稳定结构——如,内侧副韧带深层和后斜韧带——是损伤最为多见的膝关节韧带性结构。 | Coen A. Wijdicks, PhD Chad J. Griffith, MD Steinar Johansen, MD Lars Engebretsen, MD, PhD Robert F. LaPrade, MD, PhD 夏志敏(译) | 2010 | 中华骨科杂志2010，30，9： | 8 |
| 5 | Remote postconditioning显示文摘 | F. Kerendi H. Kin M. E. Halkos R. Jiang A. J. Zatta Z.–Q. Zhao R. A. Guyton J. Vinten–Johansen | 2005 | Basic Research in Cardiology2005，，5： | 3 |
| 6 | 根据基础降压用药分析恩格列净在2型糖尿病合并高血压患者中的降压作用显示文摘在EMPA—REG血压试验中,与安慰剂比较,恩格列净(empagliflozin)10或25mg/d可降低2型糖尿病合并高血压患者的糖化血红蛋白、血压及体质量水平。 | Mancia G Cannon CP Tikkanen I Zeller C Ley L Woerle HJ Broedl UC Johansen OE 赵狄 练桂丽 | 2016 | 中华高血压杂志2016，24，10： | 3 |
| 7 | 北欧岩高兰(Empetrum)生态系统:功能及其对环境变化的敏感性显示文摘本文回顾了关于北欧地区岩高兰(Empetrum nigrum sap.nigrum和ssp.hermaphroditum)生态系统的知识。因为岩高兰叶片及其枯枝落叶含有丰富的酚,分解缓慢,随着有机质表土层的形成,养分存储于有机养分库中,主要由具有石南状根的植物所吸收利用。黑果岩高兰(Empetrum nigrum)亚种Hermaphroditum是强有力的养分竞争者,并且在演替后期能战胜多数植物。这是化学干扰(他感作用)和资源竞争所致。岩高兰作为一种有机体耐大气污染,在适林海岸石南丛生地,由于大气中大量氮的沉积其生长活力甚至有所增加,但是它对机械干扰及火烧非常敏感。然而,有迹象表明,空气中无机气氮的输入可对岩高兰占优势时所形成的封闭式营养循环产生干扰。 | Knud Tybirk Marie-Charlotte Nilsson Anders Michelsen Hanne Lakkenborg Kristensen Anna shevtsova Morten Tune Strandberg Marianne Johansson Knud Erik Nielsen Torben Riis-Nielsen Beate Strandberg Ib Johansen 萨仁 | 2000 | AMBIO-人类环境杂志2000，29，2： | 3 |
| 8 | A Fault Tolerant Control Scheme Using the Feasible Constrained Control Allocation Strategy显示文摘This paper investigates the necessity of feasibility considerations in a fault tolerant control system using the constrained control allocation methodology where both static and dynamic actuator constraints are considered. In the proposed feasible control allocation scheme, the constrained model predictive control(MPC) is employed as the main controller. This considers the admissible region of the control allocation problem as its constraints. Using the feasibility notion in the control allocation problem provides the main controller with information regarding the actuator′s status, which leads to closed loop system performance improvement. Several simulation examples under normal and faulty conditions are employed to illustrate the effectiveness of the proposed methodology. The main results clearly indicate that closed loop performance and stability characteristics can be significantly degraded by neglecting the actuator constraints in the main controller. Also, it is shown that the proposed strategy substantially enlarges the domain of attraction of the MPC combined with the control allocation as compared to the conventional MPC. | Mehdi Naderi Tor Arne Johansen Ali Khaki Sedigh | 2019 | International Journal of Automation and computing2019，16，5： | 2 |
| 9 | Vaccination of mice with a cocktail DNA vaccine induces a Th1-type immune response and partial protection against schistosoma japonicum infection显示文摘 | Zhang Y Taylor MG Johansen MV | 2001 | Vaccine2001，20，56： | 2 |
| 10 | Shapes and sizes of nanoscale Pb inclusions in Al显示文摘 | E. Johnson A. Johansen U. Dahmen S. Chen T. Fujii | 2001 | Materials Science & Engineering A2001，，： | 2 |
| 11 | Acromioclavicular joint injuries: indications for treatment and treatment options显示文摘 | John A. Johansen Paul W. Grutter Edward G. McFarland Steve A. Petersen | 2011 | Journal of Shoulder and Elbow Surgery2011，，2： | 2 |
| 12 | Renal Hemodynamic Effect of Sodium-Glucose Cotransporter 2 Inhibition in Patients With Type 1 Diabetes Mellitus显示文摘 | David Z.I. Cherney Bruce A. Perkins Nima Soleymanlou Maria Maione Vesta Lai Alana Lee Nora M. Fagan Hans J. Woerle Odd Erik Johansen Uli C. Broedl Maximilian von Eynatten | 2014 | Circulation2014，，： | 2 |
| 13 | Improved void fraction determination by means of multibeam gamma-ray attenuation measurements显示文摘 | Abro E Johansen G A | 1999 | Flow Measurement and Instrumentation1999，10，2： | 2 |
| 14 | 国际油气生产者协会(OGP)与石油天然气工业用标准显示文摘 | Alf Reidar Johansen | 2004 | 石油工业技术监督2004，20，11： | 2 |
| 15 | European and Asian guidelines on management and prevention of catheter-associated urinary tract infections显示文摘 | Peter Tenke Bela Kovacs Truls E. Bjerklund Johansen Tetsuro Matsumoto Paul A. Tambyah Kurt G. Naber | 2007 | International Journal of Antimicrobial Agents2007，，： | 2 |
| 16 | Esmolol potentiates reduction of minimum alveolar isoflurane concentration by alfentanil显示文摘 | JOHANSEN JW SCHNEIDER G WINDSOR AM | 1998 | Anesth Analg1998，87，1： | 1 |
| 17 | Packing of aggregate: an alternative tool to determine the optimal aggregate 显示文摘 | Goltermann P Johansen V Palbal L | 1997 | ACI Material Journal1997，94，5： | 1 |
| 18 | Antidepressant medications and risk for cancer显示文摘 | Johansen C Mellemkjaer L | 2000 | Epidemiology2000，11，2： | 1 |
| 19 | Treatment of chronic subdural hematoma by burr-hole craniostomy in adults influence of some factors on postoperative recurrence 显示文摘 | STANISIC M LUND - JOHANSEN M MAHESPARAN R | 2005 | Acta Neurochir ( wien )2005，147，12： | 1 |
| 20 | A note on auxiliary panicle filters 显示文摘 | JOHANSEN A M DOUCET A | 2008 | Statistics and Probability Letters2008，78，12： | 1 |
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