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| 1 | Clinical applications of feature-tracking cardiac magnetic resonance imaging显示文摘Cardiovascular diseases represent the leading cause of mortality and morbidity in the western world. Assessment of cardiac function is pivotal for early diag-nosis of primitive myocardial disorders, identification of cardiac involvement in systemic diseases, detection of drug-related cardiac toxicity as well as risk stratification and monitor of treatment effects in patients with heart failure of various etiology. Determination of ejection fraction with different imaging modalities currently represents the gold standard for evaluation of cardiac function. However, in the last few years, cardiovascular magnetic resonance feature tracking techniques has emerged as a more accurate tool for quantitative evalu-ation of cardiovascular function with several parameters including strain, strain-rate, torsion and mechanical dispersion. This imaging modality allows precise quantification of ventricular and atrial mechanics by directly evaluating myocardial fiber deformation. The purpose of this article is to review the basic principles, current clinical applications and future perspectives of cardiovascular magnetic resonance myocardial feature tracking, highlighting its prognostic implications. | Daniele Muser Simon A Castro Pasquale Santangeli Gaetano Nucifora | 2018 | World Journal of Cardiology2018，10，11： | 4 |
| 2 | Enhanced dissolution and systemic availability of albendazole formulated as solid dispersions显示文摘 | Silvina G. Castro Sergio F. Sanchez Bruni Lucí a P. Urbizu Alejandra Confalonieri Laura Ceballos Carlos E. Lanusse Daniel A. Allemandi Santiago D. Palma | 2013 | Pharmaceutical Development and Technology2013，，2： | 2 |
| 3 | Improved Albendazole Dissolution Rate in Pluronic 188 Solid Dispersions显示文摘 | Silvina G. Castro Sergio Sanchez Bruni Carlos E. Lanusse Daniel A. Allemandi Santiago D. Palma | 2010 | AAPS PharmSciTech2010，，4： | 2 |
| 4 | High-resolution patterns of palaeoenvironmental changes during the Little Ice Age and the Medieval Climate Anomaly in the northwestern Iberian Peninsula显示文摘to identify plant macrofossils,estimate peat humification and calculate hydroclimatic indices based on current bog species,with the overall aim of determining the climate conditions associated with evolution of the bog during the Medieval Climate Anomaly and the Little Ice Age.These proxies,together with historical and climate data,proved to be good indicators of the changes in bog surface wetness.Analysis:of the core led to identification of 9 different periods:two corresponding to the so-called Medieval Climate Anomaly(930 to 1345 AD,1075–665 calibrated years before present[cal.yr BP]);four corresponding to the Little Ice Age(1345 to 1905 AD;665–105 cal yr BP);and three corresponding to the last century(1905 to 2000 AD).The findings revealed a generally dry climate that lasted until the 14th century,followed by a transition to a long period with a more humid,but characteristically very variable climate,which ended at the beginning of the 20th century and was followed by a rapid transition to more humid conditions and finally,a change to drier conditions.The Medieval Climate Anomaly was indicated by the abundance of dry-adapted mosses(Leucobryum glaucum,Hypnum cupressiforme)and characterized by warm dry conditions and high levels of peat humification,with alternating wet phases.The LIA period was dated by a large abundance of Sphagnum species(an indicator of wetness)and a gradual increase in the humification index.However,four different climate phases were differentiated in this period.High-resolution reconstruction of the evolution of the CVM bog and the multiproxy approach have together enabled a more detailed identification of climatic variations in this area,which are generally consistent with the global models,as well as better definition of the elusive climatic oscillations in the last millennium and confirmation of the importance of local modulation of global models.The study provides new information and a detailed chronology of climatic events that will help to refine local modulation of the climate evolution model in the still quite unexplored region of the NW Iberian Peninsula,a key area for understanding the paleoclimatic dynamics in SW Europe. | Daniel Castro Martin Souto Maria Isabel Fraga Eduardo Garcia-Rodeja Sebastian Perez-Diaz Jose Antonio Lopez Saez Xabier Pontevedra-Pombal | 2020 | Geoscience Frontiers2020，11，5： | 2 |
| 5 | Infusion of autologous bone marrow mononuclear cells through hepatic artery results in a short-term improvement of liver function in patients with chronic liver disease: a pilot randomized controlled study显示文摘 | Andre Castro Lyra Milena Botelho Pereira Soares Luiz Flavio Maia da Silva Eduardo Lorens Braga Sheilla A. Oliveira Marcos Fraga Fortes Andre Goyanna Pinheiro Silva Daniele Brustolim Bernd Genser Ricardo Ribeiro dos Santos Luiz Guilherme Costa Lyra | 2010 | European Journal of Gastroenterology & Hepatology2010，，1： | 2 |
| 6 | Genetic ancestry analysis in non-alcoholic fatty liver disease patients from Brazil and Portugal显示文摘AIM:To study the association between genetic ancestry,non-alcoholic fatty liver disease(NAFLD) metabolic characteristics in two cohorts of patients,from Brazil and Portugal. METHODS:We included 131 subjects from Brazil [(n = 45 with simple steatosis(S. Steatosis) and n = 86 with nonalcoholic steatohepatitis(NASH)] and 90 patients from Portugal(n = 66,S. Steatosis; n = 24,NASH). All patients had biopsy-proven NAFLD. In histologic evaluation NAFLD activity score was used to assess histology and more than 5 points defined NASH in this study. Patients were divided into two groups according to histology diagnosis:simple steatosis or non-alcoholic statohepatitis. Genetic ancestry was assessed using real-time polymerase chain reaction. Seven ancestry informative markers(AT3-I/D,LPL,Sb19.3,APO,FYNull,PV92,and CKMM) with the greatest ethnicgeographical differential frequencies(≥ 48%) were used to define genetic ancestry. Data were analyzed using R PROJECTS software. Ancestry allele frequencies between groups were analyzed by GENEPOP onlineand the estimation of genetic ancestry contribution was evaluated by ADMIX-95 software. The 5% alpha-error was considered as significant(P < 0.05). RESULTS:In the Brazilian sample,NASH was significantly more frequent among the elderly patients with diabetes(NASH 56 ± 1.1 years old vs S. Steatosis 51 ± 1.5 years old,P = 3.7 x 10-9),dyslipidemia(NASH 63% vs S. Steatosis 37%,P = 0.009),higher fasting glucose levels(NASH 124 ± 5.2 vs S. Steatosis 106 ± 5.3,P = 0.001) and Homeostatic Model of Assessment index > 2.5 [NASH 5.3(70.8%) vs S. Steatosis 4.6(29.2%) P = 0.04]. In the Portuguese study population,dyslipidemia was present in all patients with NASH(P = 0.03) and hypertension was present in a larger percentage of subjects in the S. Steatosis group(P = 0.003,respectively). The genetic ancestry contribution among Brazilian and Portuguese individuals with NASH was similar to those with S. Steatosis from each cohort(Brazilian cohort:P = 0.75; Portuguese cohort:P = 0.97). Nonetheless,the genetic ancestry contribution of the Brazilian and Portuguese population were different,and a greater European and Amerindian ancestry contribution was detected in the Portuguese population while a higher African genetic ancestry contribution was observed in Brazilian population of both NASH and S. Steatosis groups.CONCLUSION:There was no difference between the genetic ancestry contribution among Brazilian and Portuguese individuals with NASH and S. Steatosis from each cohort. | Lourianne Nascimento Cavalcante Jose Tadeu Stefano Mariana V Machado Daniel F Mazo Fabiola Rabelo Kiyoko Abe Sandes Flair Jose Carrilho Helena Cortez-Pinto Andre Castro Lyra Claudia P de Oliveira | 2015 | World Journal of Hepatology2015，7，10： | 2 |
| 7 | 试验室研究一种新型透水性混凝土路面砖的块型设计过程显示文摘本文介绍一种专门为城市透水性路面而设计的混凝土路面砖的块型。Cantabria大学与当地一家生产企业合作,并得到地方政府的支持,其目的是在西班牙北部应用透水型路面砖作为城市可持续性排水系统。在提出多个不同外形和尺寸的块型设计方案后,根据路面开孔率、砖连锁咬合接触面和美学角度,先从理论上进行初步对比,选择一种块型——有四种不同形状的透水槽沟;然后在Cantabia大学公路试验室里进行测试,检测不同形状的开孔对路面透水性能的影响。共进行两组测试,第一组假设路面开孔存在不同堵塞状况和坡度,以确定最佳的开孔形状;第二组用选定的混凝土路面砖,分析透水性路面的水径流。根据初步试验结果,生产企业订制模型、生产了第一批新型混凝土路面砖,并已着手推向市场。新型透水性混凝土路面砖的设计研究过程经历了无数次成功和失败,本文仅为丰富技术探讨内容,无意使其成为技术导则。 | Daniel Castro J.R.Bayon Jorge Rodriguez Nelson Gonzalez-Angullo 陈义荣(译) 杜建东(校) 刘黎(校) | 2008 | 建筑砌块与砌块建筑2008，，4： | 2 |
| 8 | Removal of ammonium via simultaneous nitriflcation-denitrification nitrite-shortcut in a single packed-bed batch reactor显示文摘 | Leonidia Maria Castro Daniel Elotsa Pozzi Eugenio Foresti | 2009 | Bioresource Technology2009，100，3： | 1 |
| 9 | Feature Extraction for Moving Objects Tracking System in Indoor Environments 显示文摘 | Daniel Castro Urbano Nunes Antonio Ruano | 1998 | Journal of Engineering and Applied Science (S1819-6608)1998，7，5： | 1 |
| 10 | Removal of ammonium via simultaneous nitrification-denitrifieation nitrite-shortcut in a single packed-bed batchreactor 显示文摘 | Castro Daniel L Pozzi E Foresti E | 2009 | Bioresource Technology2009，100，3： | 1 |
| 11 | We Need More than a 'Good Samaritan' Law for Cybersecurity Information Sharing 显示文摘 | Daniel Castro | 2012 | Cybersecurity Science & Technology2012，，5： | 1 |
| 12 | Toward pose - invariant 2 - D face recognitionthrough point distribution models and facial symmetry显示文摘 | Daniel Gonzalez - Jimenez JoseLuis Alba - Castro | 2007 | IEEE Transactions on Information Forensics and Security2007，2，3： | 1 |
| 13 | Epidemiology of Invasive Fungal Infections in Patients with Acquired Immunodeficiency Syndrome at a Reference Hospital for Infectious Diseases in Brazil显示文摘 | Renata Buccheri Oliveira Jane Harumi Atobe Simone Aparecida Souza Daniel Wagner Castro Lima Santos | 2014 | Mycopathologia . 2014 (1-2)2014，，1： | 1 |
| 14 | Removal of ammonium via simultaneous nitrification-dentrifieation nitrite-shortcut in a single packed-bed batch batch i'eactor 显示文摘 | Leonidia Mafia Castro Daniel Elolsa Pozzi Eugenio Foresti | 2009 | Bioresource Technology2009，，100： | 1 |
| 15 | High-Yield Direct Synthesis of Mg2FeH6 from the Elements by Reactive Milling显示文摘 | Leiva Daniel Rodrigo De Souza Villela André Castro Paiva-Santos Carlos de Oliveira Fruchart Daniel Miraglia Salvatore Ishikawa Tomaz Toshimi Botta Walter José | 2011 | Solid State Phenomena . 2011 (170)2011，，： | 1 |
| 16 | Neuroprotective effect of exercise in rat hippocampal slices submitted to in vitro ischemia is promoted by decrease of glutamate release and pro‐apoptotic markers显示文摘 | Flávio Afonso Gon?alves Mour?o Hércules Ribeiro Leite Luciana Estefani Drumond Carvalho Talita Hélen Ferreira e Vieira Mauro Cunha Xavier Pinto Daniel Castro Medeiros Ian Lara Lamounier Andrade Daniela Fontes Gon?alves Grace Schenatto Pereira Márcio Flávi | 2014 | J. Neurochem2014，，1： | 1 |
| 17 | Bayesian modeling of COVID-19 cases with a correction to account for under-reported cases显示文摘The novel of COVID-19 disease started in late 2019 making the worldwide governments came across a high number of critical and death cases,beyond constant fear of the collapse in their health systems.Since the beginning of the pandemic,researchers and authorities are mainly concerned with carrying out quantitative studies(modeling and predictions)overcoming the scarcity of tests that lead us to under-reporting cases.To address these issues,we introduce a Bayesian approach to the SIR model with correction for underreporting in the analysis of COVID-19 cases in Brazil.The proposed model was enforced to obtain estimates of important quantities such as the reproductive rate and the average infection period,along with the more likely date when the pandemic peak may occur.Several under-reporting scenarios were considered in the simulation study,showing how impacting is the lack of information in the modeling. | Anderson Castro Soares de Oliveira Lia Hanna Martins Morita Eveliny Barroso da Silva Luiz Andre Ribeiro Zardo Cor Jesus Fernandes Fontes Daniele Cristina Tita Granzotto | 2020 | Infectious Disease Modelling2020，5，1： | 1 |
| 18 | Analysis of Percolation of the Stabilized Suspensions of TiO2 and SiO2 Nanoparticles in Soil Columns Simulating Landfill Layers显示文摘 | Elizabeth Mendes de Oliveira Daniele Aparecida Nogueira Luis CarlosRolim Lopes Jose Flavio Silveira Feiteira Jose Adilson de Castro | 2016 | Journal of Mechanics Engineering and Automation2016，6，1： | 1 |
| 19 | Plasma cystatin C for prediction of 1-year cardiac events in Mediterranean patients with non-ST elevation acute coronary syndrome显示文摘 | Nevio Taglieri Daniel J. Fernandez-Berges Wolfgang Koenig Luciano Consuegra-Sanchez José Maria Cruz Fernandez Nicolas Roberto Robles Pedro Luis Sánchez Alfonso Castro Beiras Pedro Maria Montes Orbe Juan Carlos Kaski | 2009 | Atherosclerosis2009，，1： | 1 |
| 20 | A variable time delay compensator for multivariable linear processes 显示文摘 | Saffer II Daniel R Castro Jorge J | 2005 | Journal of Process Control2005，15，2： | 1 |
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