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| 1 | SIMS U-Pb zircon age of a tuff layer in the Meishucun section, Yunnan, southwest China: Constraint on the age of the Precambrian-Cambrian boundary显示文摘Determination of the age of the Precambrian-Cambrian boundary is critical in understanding early evolution of life on Earth. SIMS U-Pb zircon analyses of the Bed 5 tuff layer of the Meishucun section were carried out closely following the guidance of cathodoluminescence images, and the majority of analyses were conducted on the oscillatory zircon grains. Thirteen measurements yield a highly reliable Concordia U-Pb age of 536.7 ± 3.9 Ma for the Bed 5 horizon. A grand mean of 206Pb/238U age of 535.2± 1.7 Ma (MSWD = 0.53) is calculated based on 13 concordant SIMS measurements of this study and 4 nano-SIMS measurements of Sawaki et al., which is the best estimate of the deposition age of the tuff layer within Bed 5 in the Meishucun section. This age has provided a robust age constraint on the significant Precambrian-Cambrian boundary strata in southern China, which independently suggested the placement of the Precambrian-Cambrian boundary at the bottom of the Xiaowaitoushan Member (Marker A). | RiXiang Zhu XianHua Li XianGuang Hou YongXin Pan Fei Wang ChengLong Deng HuaiYu He | 2009 | Science China Earth Sciences2009，52，9： | 24 |
| 2 | Emergy footprint evaluation of hydropower projects显示文摘In the past thirty years, various hydropower projects, some with a dam height of over 300 m, have been planned and constructed within China. It is inevitable that these will have sizable effects on the environment, and it is crucial therefore to reasonably evaluate and control adverse effects. In this paper, the transformities of various items for hydropower projects were systematically analyzed, and an emergy footprint model for the projects was developed based on ecological footprint analyses and emergy theory, so that it can quantitatively evaluate the effects on the environment, both positive and negative, resulting from the whole process of planning, constructing and operating the projects. As an example, the effects of a large-scale hydropower project, the 'LP project', were investigated. The results showed that the hydropower projects have strong positive effects on the environment and can even in the short term balance the emergy footprint appropriation resulting from the construction and operation of the hydropower projects. Finally, suggestions were presented for the design of hydropower projects. | WU JianHua HE ChengLong XU WeiLin | 2013 | Science China(Technological Sciences)2013，56，9： | 7 |
| 3 | Rapid drift of the Tethyan Himalaya terrane before two-stage India-Asia collision显示文摘The India-Asia collision is an outstanding smoking gun in the study of continental collision dynamics.How and when the continental collision occurred remains a long-standing controversy.Here we present two new paleomagnetic data sets from rocks deposited on the distal part of the Indian passive margin,which indicate that the Tethyan Himalaya terrane was situated at a paleolatitude of∼19.4°S at∼75 Ma and moved rapidly northward to reach a paleolatitude of∼13.7°N at∼61 Ma.This implies that the Tethyan Himalaya terrane rifted from India after∼75 Ma,generating the North India Sea.We document a new two-stage continental collision,first at∼61 Ma between the Lhasa and Tethyan Himalaya terranes,and subsequently at∼53−48 Ma between the Tethyan Himalaya terrane and India,diachronously closing the North India Sea from west to east.Our scenario matches the history of India-Asia convergence rates and reconciles multiple lines of geologic evidence for the collision. | Jie Yuan Zhenyu Yang Chenglong Deng Wout Krijgsman Xiumian Hu Shihu Li Zhongshan Shen Huafeng Qin Wei An Huaiyu He Lin Ding Zhengtang Guo Rixiang Zhu | 2021 | National Science Review2021，8，7： | 7 |
| 4 | Human ACE2-Functionalized Gold“Virus-Trap”Nanostructures for Accurate Capture of SARS-CoV-2 and Single-Virus SERS Detection显示文摘The current COVID-19 pandemic urges the extremely sensitive and prompt detection of SARS-CoV-2 virus.Here,we present a Human Angiotensin-converting-enzyme 2(ACE2)-functionalized gold“virus traps”nanostructure as an extremely sensitive SERS biosensor,to selectively capture and rapidly detect S-protein expressed coronavirus,such as the current SARS-CoV-2 in the contaminated water,down to the single-virus level.Such a SERS sensor features extraordinary 106-fold virus enrichment originating from high-affinity of ACE2 with S protein as well as“virus-traps”composed of oblique gold nanoneedles,and 109-fold enhancement of Raman signals originating from multi-component SERS effects.Furthermore,the identification standard of virus signals is established by machine-learning and identification techniques,resulting in an especially low detection limit of 80 copies mL^(−1) for the simulated contaminated water by SARS-CoV-2 virus with complex circumstance as short as 5 min,which is of great significance for achieving real-time monitoring and early warning of coronavirus.Moreover,here-developed method can be used to establish the identification standard for future unknown coronavirus,and immediately enable extremely sensitive and rapid detection of novel virus. | Yong Yang Yusi Peng Chenglong Lin Li Long Jingying Hu Jun He Hui Zeng Zhengren Huang Zhi-Yuan Li Masaki Tanemura Jianlin Shi John R.Lombardi Xiaoying Luo | 2021 | Nano-Micro Letters2021，13，7： | 6 |
| 5 | A numerical and experimental study of a dual-function solar collector integrated with building in passive space heating mode显示文摘A newly designed solar collector named dual-function solar collector is proposed.The dual-function solar collector integrated with building can perform in two different modes:working as a passive space heating collector in cold sunny days such as in winter,or working as a facade water heating collector in hot days such as in summer.An experimental study has been carried out to investigate the performance of the novel system in space heating mode,whilst,the dynamic numerical model has been established and validated.The experimental and numerical results show that during the period of the measurement from 9:00 to 17:00,the mean indoor temperature was up to 24.7°C while the mean ambient temperature was only 4.8°C,and a temperature stratification was present in the room.Moreover,a numerical study on the effect of optical property of coatings has been carried out. | JI Jie LUO ChengLong SUN Wei HE Wei PEI Gang HAN ChongWei | 2010 | Chinese Science Bulletin2010，55，15： | 5 |
| 6 | Effect of a dual-function solar collector integrated with building on the cooling load of building in summer显示文摘As a building integrated solar thermal system,the dual-function solar collector integrated with building works for passive space heating in cold winter season,and for water heating in warm seasons.In this paper,the study is made on the dual-function solar collector integrated with building when it works in water heating mode with natural circulation.The coupled model of the collector and building's environment is established and validated.A numerical simulation is achieved to show the thermal effect of the novel system on the building in summer.By comparing with the cooling loads of the rooms with or without the novel collector in summer,the results show that when in summer,the novel solar system is available for serving hot water,and it does not have the summer overheating problem,and can even improve the thermal environment of its building slightly. | JI Jie LUO ChengLong SUN Wei HE Wei JIANG QingYang | 2010 | Chinese Science Bulletin2010，55，31： | 5 |
| 7 | Technological Parameters and Design of Bionic Integrated Honeycomb Plates显示文摘 | Chenglong Gu Jianxun Liu Jinxiang Chen Chenglin He Yun Lu Yong Zhao | 2014 | Journal of Bionic Engineering2014，11，1： | 4 |
| 8 | An improved approach for the application of Trombe wall system to building construction with selective thermo-insulation faades显示文摘An improved Trombe wall is proposed to adapt to building construction with selective thermo-insula-tion faades (internal and cavity wall insulation, but not external wall insulation system). The case study is conducted in Xining, Capital city of Qinghai province in China, where the general building faades are mostly selective thermo-insulation faades to fight against the severe cold. A numerical analysis is undertaken to show the effects on the improvement of the building's thermal environment by comparing the improved Trombe wall system with the classical Trombe wall system. The operating efficiency of the improved Trombe wall can be up to 33.85%, an increase of 56%. The results show that the improved Trombe wall works more effectively than the classical Trombe wall system in utilizing solar energy for the sample building. | JI Jie LUO ChengLong SUN Wei YU HanCheng HE Wei PEI Gang | 2009 | Chinese Science Bulletin2009，54，11： | 3 |
| 9 | Overview of the Solar Polar Orbit Telescope Project for Space Weather Mission显示文摘The Solar Polar ORbit Telescope(SPORT) project for space weather mission has been under intensive scientific and engineering background studies since it was incorporated into the Chinese Space Science Strategic Pioneer Project in 2011.SPORT is designed to carry a suite of remote-sensing and in-situ instruments to observe Coronal Mass Ejections(CMEs),energetic particles,solar high-latitude magnetism,and the fast solar wind from a polar orbit around the Sun.The first extended view of the polar regions of the Sun and the ecliptic enabled by SPORT will provide a unique opportunity to study CME propagation through the inner heliosphere,and the solar high-latitude magnetism giving rise to eruptions and the fast solar wind.Coordinated observations between SPORT and other spaceborne/ground-based facilities within the International Living With a Star(ILWS) framework can significantly enhance scientific output.SPORT is now competing for official selection and implementation during China's 13 th Five-Year Plan period of 2016-2020. | XIONG Ming LIU Ying LIU Hao LI Baoquan ZHENG Jianhua ZHANG Cheng XIA Lidong ZHANG Hongxin RAO Wei CHEN Changya SUN Weiying WU Xia DENG Yuanyong HE Han JIANG Bo WANG Yuming WANG Chuanbing SHEN Chenglong ZHANG Haiying ZHANG Shenyi YANG Xuan SANG Peng WU Ji | 2016 | 空间科学学报2016，36，3： | 3 |
| 10 | A high-performance bio-tissue imaging method using air flow-assisted desorption electrospray ionization coupled with a high-resolution mass spectrometer显示文摘Mass spectrometry imaging (MSI) technology can simultaneously obtain the spatial distribution of thousands of chemical compounds and has unique advantages compared to other techniques that allow mapping the surface of bio-tissue. Here, we combined an air flow-assisted desorption electrospray ionization (AFADESI) MSI device with a high-resolution mass spectrometer to optimize the system parameters and achieve more accurate spatial distribution characteristics for compounds of interest while investigating bio-tissue sections. The platform set-up, required instrumentation, sample pretreatment, parameter optimization and bio-tissue characterization are described and discussed.Finally, the parameter conditions that can provide optimal ionic intensity and enhanced resolution were confirmed. The reasonable resolution and sensitivity improvements of AFADESI-MSI have been achieved through tandem a high-resolution mass spectrometer system, therefore, it would be a promising technique for the bio-tissue imaging analysis. | Yiwei Lv Tiegang Li Chengan Guo Chenglong Sun Fei Tang Luojiao Huang Zhigang Luo Xin Li Ruiping Zhang Qingce Zang Jiuming He Zeper AbliZ | 2019 | Chinese Chemical Letters2019，30，2： | 2 |
| 11 | A rapid and sensitive UPLC–MS/MS method for quantitative determination of arformoterol in rat plasma, lung and trachea tissues显示文摘A rapid and sensitive ultra-performance liquid chromatography-tandem mass spectrometry(UPLC–MS/MS) method was developed and fully validated for determination of arformoterol in rat plasma, lung and trachea tissues. The chromatographic separation was performed on an Agilent XDB C8 column with gradient elution by using acetonitrile and 0.1% formic acid water. The method presented high sensitivity(LLOQ of 1.83 pg/mL for plasma and 3.90 pg/mL for lung and trachea tissue homogenates) and great linearity over the range of 1.83–458 pg/mL for plasma, 13.9–1560 pg/mL for lung and trachea tissue homogenates. No carry over effect and matrix effect were observed. The intra-and inter-day precision/accuracy were within ±15% at three quality control concentration levels. This robust method was successfully applied to the pharmacokinetic, lung and trachea tissue distribution study after inhalation administration of arformoterol tartrate inhalation solution(50 m g/kg). The in vivo information indicate that arformoterol can be rapidly absorbed into blood through respiratory systems, lung and trachea tissue maintain a certain amount of arformoterol in 1 h after dosing. | Chenglong Sun Jiuming He Hongbo Wu Xiaowei Song Jiangshuo Li Luojiao Huang Xiaoyu Xu Manjiangcuo Wang Ruiping Zhang Zeper Abliz | 2018 | Chinese Chemical Letters2018，29，8： | 2 |
| 12 | Geo-location for Ground Target with Multiple Observations Using Unmanned Aerial Vehicle显示文摘In order to improve the target location accuracy of unmanned aerial vehicle(UAV),a novel target location method using multiple observations is proposed.Firstly,the camera intrinsic parameters are calibrated.Then,the weighted least squares estimation is used to improve the localization precision because the traditional crossover method is vulnerable to noise and has low precision.By repeatedly measuring the same target point,a nonlinear observation equation is established and then covered to linear equations using Taylor expansion.The weighted matrix is obtained according to the height of the measurement point and the camera optic axis pointing angle,and then the weighted least squares estimation is used to calculate the target position iteratively.Finally,the effectiveness and robustness of this method is verified by numerical simulation and flight test.The results show that this method can effectively improve the precision of target location. | Xu Cheng He Chenglong Huang Daqing | 2018 | Transactions of Nanjing University of Aeronautics and Astronautics2018，35，5： | 1 |
| 13 | Low-depth whole genome sequencing reveals copy number variations associated with higher pathologic grading and more aggressive subtypes of lung non-mucinous adenocarcinoma显示文摘Objective:Histology grade,subtypes and TNM stage of lung adenocarcinomas are useful predictors of prognosis and survival.The aim of the study was to investigate the relationship between chromosomal instability,morphological subtypes and the grading system used in lung non-mucinous adenocarcinoma(LNMA).Methods:We developed a whole genome copy number variation(WGCNV)scoring system and applied next generation sequencing to evaluate CNVs present in 91 LNMA tumor samples.Results:Higher histological grades,aggressive subtypes and more advanced TNM staging were associated with an increased WGCNV score,particularly in CNV regions enriched for tumor suppressor genes and oncogenes.In addition,we demonstrate that 24-chromosome CNV profiling can be performed reliably from specific cell types(<100 cells)isolated by sample laser capture microdissection.Conclusions:Our findings suggest that the WGCNV scoring system we developed may have potential value as an adjunct test for predicting the prognosis of patients diagnosed with LNMA. | Zheng Wang Lin Zhang Lei He Di Cui Chenglong Liu Liangyu Yin Min Zhang Lei Jiang Yuyan Gong Wang Wu Bi Liu Xiaoyu Li David S Cram Dongge Liu | 2020 | Chinese Journal of Cancer Research2020，32，3： | 1 |
| 14 | Occurrence and investigation of enteric viral infections in pigs with diarrhea in China显示文摘 | Qian Zhang Ruiming Hu Xibiao Tang Chenglong Wu Qigai He Zhanqin Zhao Huanchun Chen Bin Wu | 2013 | Archives of Virology2013，，： | 1 |
| 15 | Calibration and adjustment of center of mass(COM) based on EKF during in-flight phase显示文摘The electrostatic accelerometer,assembled on gravity satellite,serves to measure all non-gravitational accelerations caused by atmosphere drag or solar radiation pressure,etc.The proof-mass center of the accelerometer needs to be precisely positioned at the center of gravity satellite,otherwise,the offset between them will bring measurement disturbance due to angular acceleration of satellite and gradient.Because of installation and measurement errors on the ground,fuel consumption during the in-flight phase and other adverse factors,the offset between the proof-mass center and the satellite center of mass is usually large enough to affect the measurement accuracy of the accelerometer,even beyond its range.Therefore,the offset needs to be measured or estimated,and then be controlled within the measurement requirement of the accelerometer by the center of mass(COM) adjustment mechanism during the life of the satellite.The estimation algorithm based on EKF,which uses the measurement of accelerometer,gyro and magnetometer,is put forward to estimate the offset,and the COM adjustment mechanism then adjusts the satellite center of mass in order to make the offset meet the requirement.With the special configuration layout,the COM adjustment mechanism driven by the stepper motors can separately regulate X,Y and Z axes.The associated simulation shows that the offset can be con-trolled better than 0.03 mm for all the axes with the method mentioned above. | DONG Feng LIAO He JIA ChengLong XIA XiaoJing | 2009 | Science China(Technological Sciences)2009，52，5： | 1 |
| 16 | Study on Forced Straight-Line Guidance for the Final Translation Phase of Spacecraft Rendezvous显示文摘Aimed at the problem of final translation of space rendezvous for the applications such as docking,inspection and tracking,optimal straight-line guidance algorithm based on pulse/continuous low-thrust in the context of Clohessy-Wiltshire dynamics is proposed.Two modes of guidance strategy:varying-speed and fixed-speed approaching scheme for V-bar and R-bar approach by using constant/finite low-thrust propulsion respectively are studied,and the corresponding fuel-optimal conditions are obtained.Numerical simulation is conducted to verify and test the proposed algorithms.The results show that there is generally no different between the fuel consumptions by using the two different approaching modes for V-bar case.However,the conclusion for Rbar case is different that the using of continuous low-thrust cost more fuel and transfer time. | Baichun Gong Chenglong He Degang Zhang | 2020 | Computer Modeling in Engineering & Sciences2020，，1： | 1 |
| 17 | Occurrence and investigation of enteric viral infections in pigs with diarrhea in China显示文摘 | Qian Zhang Ruiming Hu Xibiao Tang Chenglong Wu Qigai He Zhanqin Zhao Huanchun Chen Bin Wu | 2013 | Archives of Virology2013，，8： | 1 |
| 18 | A novel SIRT6 activator ameliorates neuroinflammation and ischemic brain injury via EZH2/FOXC1 axis显示文摘Ischemic stroke is the second leading cause of death worldwide with limited medications and neuroinflammation was recognized as a critical player in the progression of stroke,but how to control the overactive neuroinflammation is still a long-standing challenge.Here,we designed a novel SIRT6 activator MDL-811 which remarkably inhibited inflammatory response in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages and primary mouse microglia,which were abolished by silencing SIRT6.RNA-seq screening identified the forkhead box C1 (Foxc1) is a key gene evoked by MDL-811stimulation and is required for the anti-inflammatory effects of MDL-811.We found MDL-811-activated SIRT6 directly interacted with enhancer of zeste homolog 2 (EZH2) and promoted deacetylation of EZH2 which could bind to the promoter of Foxc1 and upregulate its expression to modulate inflammation.Moreover,our data demonstrated that MDL-811 not only ameliorated sickness behaviors in neuroinflammatory mice induced by LPS,but also markedly reduced the brain injury in ischemic stroke mice in addition to promoting long-term functional recovery.Importantly,MDL-811 also exhibited strong anti-inflammatory effects in human monocytes isolated from ischemic stroke patients,underlying an interesting translational perspective.Taken together,MDL-811 could be an alternative therapeutic candidate for ischemic stroke and other brain disorders associated with neuroinflammation. | Tailin He Jialin Shang Chenglong Gao Xin Guan Yingyi Chen Liwen Zhu Luyong Zhang Cunjin Zhang Jian Zhang Tao Pang | 2021 | Acta Pharmaceutica Sinica B2021，11，3： | 1 |
| 19 | B-doped SiO_(x) composite with three dimensional conductive network for high performance lithium-ion battery anode显示文摘Currently,the practical application of SiO_(x) still has a huge hindrance in the area of lithium ion battery,because it is unable to achieve an effective contact with surrounding conducting materials,resulting in failure to form lithium ion migration tunnels.In this work,we presented a facile method to synthesize the B-doped SiOx composite by adhering SiO_(x) particles with MWCNT(multi-walled carbon nanotube)under the assistance of lithium metaborate(LiBO_(2)).LiBO_(2),as a sintering aid,not only can react with SiO_(x) to form a compacted framework,but also build a three-dimensional(3D)conductive network for ions transportation.Furthermore,B-SiO_(x)@CNT@LBO anode delivers a remarkable lithium storage performance in terms of long cycles and high rate capability.A full cell coupled with NCM622 cathode achieves a high energy density of 429.5 Wh kg^(-1) based on the total mass of cathode. | Wenjie He Tengfei Zhang Zhiwei Li Jiangmin Jiang Chenglong Chen Nan Liu Hui Dou Xiao Gang Zhang | 2021 | Journal of Materiomics2021，7，4： | 0 |
| 20 | A unique subseafloor microbiosphere in the Mariana Trench driven by episodic sedimentation显示文摘Hadal trenches are characterized by enhanced and infrequent high-rate episodic sedimentation events that likely introduce not only labile organic carbon and key nutrients but also new microbes that significantly alter the subseafloor microbiosphere.Currently,the role of high-rate episodic sedimentation in controlling the composition of the hadal subseafloor microbiosphere is unknown.Here,analyses of carbon isotope composition in a~750 cm long sediment core from the Challenger Deep revealed noncontinuous deposition,with anomalous ^(14)C ages likely caused by seismically driven mass transport and the funneling effect of trench geomorphology.Microbial community composition and diverse enzyme activities in the upper~27 cm differed from those at lower depths,probably due to sudden sediment deposition and differences in redox condition and organic matter availability.At lower depths,microbial population numbers,and composition remained relatively constant,except at some discrete depths with altered enzyme activity and microbial phyla abundance,possibly due to additional sudden sedimentation events of different magnitude.Evidence is provided of a unique role for high-rate episodic sedimentation events in controlling the subsurface microbiosphere in Earth’s deepest ocean floor and highlight the need to perform thorough analysis over a large depth range to characterize hadal benthic populations.Such depositional processes are likely crucial in shaping deep-water geochemical environments and thereby the deep subseafloor biosphere. | Jiwen Liu Da-Wei Li Xinxin He Ronghua Liu Haojin Cheng Chenglong Su Mengna Chen Yonghong Wang Zhongsheng Zhao Hanyue Xu Zhangyu Cheng Zicheng Wang Nikolai Pedentchouk David J.Lea-Smith Jonathan D.Todd Xiaoshou Liu Meixun Zhao Xiao-Hua Zhang | 2024 | Marine Life Science & Technology2024，6，1： | 0 |
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