|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Quantitative determination of AI-2 quorum-sensing signal of bacteria using high performance liquid chromatography–tandem mass spectrometry显示文摘Autoinducer 2(AI-2), an important bioactive by-product of the Lux S-catalyzed S-ribosylhomocysteine cleavage reaction in the activated-methyl-cycle, has been suggested to serve as a universal intra- and inter-species signaling molecule. The development of reliable and sensitive methods for quantitative determination of AI-2 is highly desired.However, the chemical properties of AI-2 cause difficulty in its quantitative analysis.Herein, we report a high performance liquid chromatography-tandem mass spectrometric method that enables reproducible and sensitive measurement of AI-2 concentrations in complex matrixes. 4,5-Dimethylbenzene-1,2-diamine(DMBDM), an easy-to-obtain commercial reagent, was used for the derivatization treatment. The assay was linear in the concentration range of 1.0–1000 ng/m L(R^2= 0.999) and had a lower limit of quantification of0.58 ng/m L. The method exhibited several advantages, e.g., high selectivity, wide linear response range, and good sensitivity. Furthermore, the effectiveness of the method was further validated through measuring AI-2 concentrations in the cell-free culture supernatant from Escherichia coli wild type. | Fang Xu Xiangning Song Peijie Cai Guoping Sheng Hanqing Yu | 2017 | Journal of Environmental Sciences2017，29，2： | 8 |
| 2 | Recent progress of integrated circuits and optoelectronic chips显示文摘Integrated circuits(ICs)and optoelectronic chips are the foundation stones of the modern information society.The IC industry has been driven by the so-called'Moore's law'in the past 60 years,and now has entered the post Moore's law era.In this paper,we review the recent progress of ICs and optoelectronic chips.The research status,technical challenges and development trend of devices,chips and integrated technologies of typical IC and optoelectronic chips are focused on.The main contents include the development law of IC and optoelectronic chip technology,the IC design and processing technology,emerging memory and chip architecture,brain-like chip structure and its mechanism,heterogeneous integration,quantum chip technology,silicon photonics chip technology,integrated microwave photonic chip,and optoelectronic hybrid integrated chip. | Yue HAO Shuiying XIANG Genquan HAN Jincheng ZHANG Xiaohua MA Zhangming ZHU Xingxing GUO Yahui ZHANG Yanan HAN Ziwei SONG Yan LIU Ling YANG Hong ZHOU Jiangyi SHI Wei ZHANG Min XU Weisheng ZHAO Biao PAN Yangqi HUANG Qi LIU Yimao CAI Jian ZHU Xin OU Tiangui YOU Huaqiang WU Bin GAO Zhiyong ZHANG Guoping GUO Yonghua CHEN Yong LIU Xiangfei CHEN Chunlai XUE Xingjun WANG Lixia ZHAO Xihua ZOU Lianshan YAN Ming LI | 2021 | Science China(Information Sciences)2021，64，10： | 7 |
| 3 | Pathological changes in the lungs and lymphatic organs of 12 COVID-19 autopsy cases显示文摘Systematic autopsy and comprehensive pathological analyses of COVID-19 decedents should provide insights into the disease characteristics and facilitate the development of novel therapeutics.In this study,we report the autopsy findings from the lungs and lymphatic organs of 12 COVID-19 decedents—findings that evaluated histopathological changes;immune cell signature and inflammatory factor expression in the lungs,spleen and lymph nodes.Here we show that the major pulmonary alterations included diffuse alveolar damage,interstitial fibrosis and exudative inflammation featured with extensive serous and fibrin exudates,macrophage infiltration and abundant production of inflammatory factors(IL-6,IP-10,TNFo?and IL-I f).The spleen and hilar lymph nodes contained lesions with tissue structure disruption and immune cell dysregulation,including lymphopenia and macrophage accumulation.These findings provide pathological evidence that links injuries of the lungs and lymphatic organs with the fatal systematic respiratory and immune malfunction in critically ill COVID-19 patients. | Qian Liu Yu Shi Jun Cai Yaqi Duan Rongshuai Wang Hongyan Zhang Qiurong Ruan Jiansha Li Lei Zhao Yifang Ping Rong Chen Liang Ren Xiaochun Fei Heng Zhang Rui Tang Xi Wang Tao Luo Xindong Liu Xuequan Huang Zhenhua Liu Qilin Ao Yong Ren Jing Xiong Zhicheng He Haibo Wu Wenjuan Fu Pengnan Zhao Xinwei Chen Guoqiang Qu Yunyun Wang Xi Wang Jia Liu Dongfang Xiang Sanpeng Xu Xiaowei Zhou Qingrui Li Jinghong Ma Heng Li Jie Zhang Sizhe Huang Xiaohong Yao Yiwu Zhou Chaofu Wang Dingyu Zhang Guoping Wang Liang Liu Xiu-Wu Bian | 2020 | National Science Review2020，7，12： | 6 |
| 4 | A single circular chromosome yeast显示文摘Dear editor,Most of the prokaryotic cells contain a single circular chromosome.In contrast, the eukaryotic cells usually contain multiple linear chromosomes. Recently, we artificially created a single linear chromosome yeast strain SY14 from native 16 chromosomes in a haploid Saccharomyces cerevisiae, which displays minor fitness defects.^1 In this study, we have created a new yeast strain which contains a single circular chromosome and apparently has not been found in nature. | Yangyang Shao Ning Lu Chen Cai Fan Zhou Shanshan Wang Zhihu Zhao Guoping Zhao Jin-Qiu Zhou Xiaoli Xue Zhongjun Qin | 2019 | Cell Research2019，29，1： | 5 |
| 5 | MODEL REDUCTION AND ACTIVE CONTROL FOR A FLEXIBLE PLATE显示文摘The internal balance technique is effective for model reduction in flexible structures, especially those with dense frequencies. However, due to the difficulty in extracting the internal balance modal coordinates from the physical sensor readings, research so far on this topic has been mostly theoretic and little on experiment or engineering applications. This paper, by working on a DSP TMS320F2812-based experiment system with a flexible plate and bringing forward an approximating approach to accessing the internal balance modal coordinates, studies the internal balance method theoretically as well as experimentally, and further designs an active controller based on the reduced model. Simulation and test results have proven the proposed approximating approach feasible and effective, and the designed controller successful in restraining the plate vibration. | Yong Xie Tong Zhao Guoping Cai | 2011 | Acta Mechanica Solida Sinica2011，24，5： | 3 |
| 6 | Concepts, processing, and recent developments in encapsulating essential oils显示文摘By the virtue of their olfactory,physicochemical,and biological characteristics,essential oils(EOs)have drawn wide attention as additives in daily chemicals like perfume or personal care products.Nevertheless,they are physicochemically unstable and susceptible to degradation or loss.Microencapsulation offers a feasible strategy to stabilize and prolong release of EO.This review summarizes the recognized benefits and functional properties of various preparation and characterization methods,wherein innovative fabrication strategies and their formation mechanisms are especially emphasized.Progress in combining detecting/measuring technologies with kinetic modelling are discussed,to give an integral approach of controlling the dynamic release of encapsulated EOs.Moreover,new development trends of EOs capsules are also highlighted. | Qirui Tian Weiqing Zhou Qiong Cai Guanghui Ma Guoping Lian | 2021 | Chinese Journal of Chemical Engineering2021，34，2： | 3 |
| 7 | Occurrence of psychrotolerant Bacillus cereus group strains in ice creams显示文摘 | Guoping Zhou Dasheng Zheng Lina Dou Quanxin Cai Zhiming Yuan | 2009 | International Journal of Food Microbiology2009，，2： | 2 |
| 8 | The genome and gene editing system of sea barleygrass provide a novel platform for cereal domestication and stress tolerance studies显示文摘The tribe Triticeae provides important staple cereal crops and contains elite wild species with wide geneticdiversity and high tolerance to abiotic stresses. Sea barleygrass (Hordeum marinum Huds.), a wildTriticeae species, thrives in saline marshlands and is well known for its high tolerance to salinity and waterlogging. Here, a 3.82-Gb high-quality reference genome of sea barleygrass is assembled de novo, with 3.69Gb (96.8%) of its sequences anchored onto seven chromosomes. In total, 41 045 high-confidence (HC)genes are annotated by homology, de novo prediction, and transcriptome analysis. Phylogenetics, nonsynonymous/synonymous mutation ratios (Ka/Ks), and transcriptomic and functional analyses provide genetic evidence for the divergence in morphology and salt tolerance among sea barleygrass, barley, andwheat. The large variation in post-domestication genes (e.g. IPA1 and MOC1) may cause interspecies differences in plant morphology. The extremely high salt tolerance of sea barleygrass is mainly attributed tolow Na+ uptake and root-to-shoot translocation, which are mainly controlled by SOS1, HKT, and NHX transporters. Agrobacterium-mediated transformation and CRISPR/Cas9-mediated gene editing systems weredeveloped for sea barleygrass to promote its utilization for exploration and functional studies of hubgenes and for the genetic improvement of cereal crops. | Liuhui Kuang Qiufang Shen Liyang Chen Lingzhen Ye Tao Yan Zhong-Hua Chen Robbie Waugh Qi Li Lu Huang Shengguan Cai Liangbo Fu Pengwei Xing Kai Wang Jiari Shao Feibo Wu Lixi Jiang Dezhi Wu Guoping Zhang | 2022 | Plant Communications2022，3，5： | 2 |
| 9 | Robust fault-tolerant control for wing flutter under actuator failure显示文摘Many control laws, such as optimal controller and classical controller, have seen their applications to suppressing the aeroelastic vibrations of the aeroelastic system. However, those control laws may not work effectively if the aeroelastic system involves actuator faults. In the current study for wing flutter of reentry vehicle, the effect of actuator faults on wing flutter system is rarely considered and few of the fault-tolerant control problems are taken into account. In this paper, we use the radial basis function neural network and the finite-time H_∞ adaptive fault-tolerant control technique to deal with the flutter problem of wings, which is affected by actuator faults, actuator saturation, parameter uncertainties and external disturbances. The theory of this article includes the modeling of wing flutter and fault-tolerant controller design. The stability of the finite-time adaptive fault-tolerant controller is theoretically proved. Simulation results indicate that the designed fault-tolerant flutter controller can effectively deal with the faults in the flutter system and can promptly suppress the wing flutter as well. | Gao Mingzhou Cai Guoping | 2016 | Chinese Journal of Aeronautics2016，29，4： | 2 |
| 10 | The relationships among structure variables of larch forests in China显示文摘Background:Larch(Larix Mill.)forests are widely distributed in the upper parts of mountainous areas in China,playing vital roles in constructing mountain landscapes and maintaining mountain environments.Despite their importance,our knowledges on the large-scale patterns of structure characteristics and the relationships between different structure variables are unclear.In this paper,we investigated 155 plots from 11 natural larch forest types across the country to explore the biogeographic patterns of the structure characteristics and the allometric relationships between different structure variables for Chinese larch forests.Results:The structure characteristics were significantly different among larch forest types.For different larch forest types,the power function fits the relationships between tree height and diameter at breast height(DBH),average DBH and stem density,and taper and stem density well,but with different exponents among larch forest types.The power exponents of the allometric relationships between tree height and DBH for different larch forest types varied from 0.61 to 0.93(mean=0.86)by standard major axis regression(SMA),and from 0.51 to 0.78(mean=0.56)by ordinary least square regression(OLS).The 50%,75%and 95%quantile regression(QR)and OLS indicated that the average DBH and taper of the L.gmelinii forests,L.gmelinii var.principis-rupprechtii forests,and L.sibirica forests were significantly correlated with stem density.Conclusions:The relationship between tree height and DBH showed a power function relationship for all larch forest types in China,but with different exponents.Overall,stem density was negatively correlated with average DBH and taper.The Sect.Larix forests exhibited stand density effect.Our findings provide an important basis for recognizing the biogeographic patterns of structure factors and for the management of larch forests in China. | Wenjing Fang Qing Zhao Qiong Cai Anwar Eziz Guoping Chen Yuhao Feng Heng Zhang Jiangling Zhu Chengjun Ji Zhiyao Tang Jingyun Fang | 2020 | Forest Ecosystems2020，7，4： | 2 |
| 11 | Piezoelectric Actuator Placement Optimization and Active Vibration Control of a Membrane Structure显示文摘The placement optimization of piezoelectric actuators and active vibration control of a membrane structure are studied in this paper. The classical linear quadratic regulator controllers are designed to suppress the unwanted vibration. Simulation results indicate that the optimal locations of piezoelectric actuators are affected deeply by the additional mass and stiffness of actuators, the computational efficiency of particle swarm optimizer is higher than that of genetic algorithm for this particular problem, and the control performance of optimally placed actuators is better than that of non-optimally placed actuators. | Xiang Liu Guoping Cai Fujun Peng Hua Zhang | 2018 | Acta Mechanica Solida Sinica2018，31，1： | 2 |
| 12 | Decoding Cortical Glial Cell Development显示文摘Mouse cortical radial glial cells(RGCs)are primary neural stem cells that give rise to cortical oligodendrocytes,astrocytes,and olfactory bulb(OB)GABAergic interneurons in late embryogenesis.There are fundamental gaps in understanding how these diverse cell subtypes are generated.Here,by combining single-cell RNA-Seq with intersectional lineage analyses,we show that beginning at around E16.5,neocortical RGCs start to generate ASCL1^(+)EGFR^(+)apical multipotent intermediate progenitors(MIPCs),which then differentiate into basal MIPCs that express ASCL1,EGFR,OLIG2,and MKI67.These basal MIPCs undergo several rounds of divisions to generate most of the cortical oligodendrocytes and astrocytes and a subpopulation of OB interneurons.Finally,single-cell ATAC-Seq supported our model for the genetic logic underlying the specification and differentiation of cortical glial cells and OB interneurons.Taken together,this work reveals the process of cortical radial glial cell lineage progression and the developmental origins of cortical astrocytes and oligodendrocytes. | Xiaosu Li Guoping Liu Lin Yang Zhenmeiyu Li Zhuangzhi Zhang Zhejun Xu Yuqun Cai Heng Du Zihao Su Ziwu Wang Yangyang Duan Haotian Chen Zicong Shang Yan You Qi Zhang Miao He Bin Chen Zhengang Yang | 2021 | Neuroscience Bulletin2021，37，4： | 2 |
| 13 | 显示文摘 | Qian JiangMiao Fang Zheng ping GuoPing Cai | 2003 | Catal Commun2003，4，： | 1 |
| 14 | ACTIVE CONTROL OF A FLEXIBLE CANTILEVER PLATE WITH MULTIPLE TIME DELAYS显示文摘Active control of a flexible cantilever plate with multiple time delays is investigated using the discrete optimal control method. A controller with multiple time delays is presented. In this controller, time delay effect is incorporated in the mathematical model of the dynamic system throughout the control design and no approximations and assumptions are made in the controller derivation, so the system stability is easily guaranteed. Furthermore, this controller is available for both small time delays and large time delays. The feasibility and e?ciency of the proposed controller are verified through numerical simulations in the end of this paper. | Longxiang Chen Ji Pan Guoping Cai | 2008 | Acta Mechanica Solida Sinica2008，21，3： | 1 |
| 15 | Optimal control method for seismically excited building structures with time-delay in control 显示文摘 | Cai Guoping Huang Jinzhi | 2002 | Journal of Engineering Mechanics ASCE2002，128，6： | 1 |
| 16 | Synthesis of N - methyl - 2 - thioimidazole resin and its complex behavior for noble metal ions 显示文摘 | Chen Yiyong Cai Guoping Wang Naidong | 1990 | Macromol Sci- chem1990，27，911： | 1 |
| 17 | Effects of electro-magnetic fields on the bioactivities in an osteoblast-like cell line (UMR-106)显示文摘 | Long Ying Cai Guoping Guan Zhicheng | 2000 | Electro-Magnetobiology2000，19，2： | 1 |
| 18 | Optimal control method for seismically excited building structures with time delay in control显示文摘 | Cai Guoping Huang Jinzhi | 2002 | Journal of Engineering Mechanics ASCE2002，128，6： | 1 |
| 19 | Effects of electro-magnetic fields on the bioactivities in an osleoblast-like cell line (UMR-106) 显示文摘 | Long Ying Cai Guoping Guan Zhicheng | 2000 | Electro-Magnetobiology2000，19，2： | 1 |
| 20 | Effects of electromagnetic fields on the bioactivities in an osteoblast-like cell line (UMR-106) 显示文摘 | Cai Guoping | 2000 | Electro-Magnetobiology2000，19，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员