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| 1 | 用法国小麦粉制作中国面条的研究Ⅰ.实验室制作挂面显示文摘将 1 0种典型的法国商品面粉和我国的 5种面条专用粉作对比 ,在实验室研究了法国小麦粉制作挂面的适宜性 .通过揉混仪测定 ,与粉质仪吸水率对比分析 ,结果表明 :制作食品时的实际吸水率与粉质吸水率没有相关性 .法国小麦粉制作的挂面存在的缺陷主要表现在色泽、麸星、表观状态等外观品质上 ,这与法国小麦粉的低加工精度和高出粉率有关 .低蛋白质含量的法国小麦粉仍具有制作挂面的良好品质 :烹煮时间短 ,硬度适中 ;筋力强、弹性足 ,耐咀嚼性好 ;不粘条、不粘牙 ,爽口滑溜 . | 赵仁勇 J P Leygue 刘长虹 R Bertrand | 2002 | 郑州工程学院学报2002，23，1： | 8 |
| 2 | Rescue associating liver partition and portal vein ligation for staged hepatectomy after portal embolization: Our experience and literature review显示文摘AIM To report a single-center experience in rescue associating liver partition and portal vein ligation for staged hepatectomy(ALPPS), after failure of previous portal embolization. We also performed a literature review.METHODS Between January 2014 and December 2015, every patient who underwent a rescue ALPPS procedure in Toulouse Rangueil University Hospital, France, was included. Every patient included had a project of major hepatectomy and a previous portal vein embolization(PVE) with insufficient future liver remnant to body weight ratio after the procedure. The ALPPS procedure was performed in two steps(ALPPS-1 and ALPPS-2), separated by an interval phase. ALPPS-2 was done within 7 to 9 d after ALPPS-1. To estimate the FLR, a computed tomography scan examination was performed 3 to 6 wk after the PVE procedure and 6 to 8 d after ALPPS-1. A transcystic stent was placed during ALPPS-1 and remained opened duringthe interval phase, in order to avoid biliary complications. Postoperative liver failure was defined using the 50-50 criteria. Postoperative complications were assessed according to the Dindo-Clavien Classification.RESULTS From January 2014 to December 2015, 7 patients underwent a rescue ALPPS procedure. Median FLR before PVE, ALPPS-1 and ALPPS-2 were respectively 263 cc(221-380), 450 cc(372-506), and 660 cc(575-776). Median FLR/BWR before PVE, ALPPS-1 and ALPPS-2 were respectively 0.4%(0.3-0.5), 0.6%(0.5-0.8), and 1%(0.8-1.2). Median volume growth of FLR was 69%(18-92) after PVE, and 45%(36-82) after ALPPS-1. The combination of PVE and ALPPS induced a growth of median initial FLR of +408 cc(254-513), leading to an increase of +149%(68-199). After ALPPS-2, 4 patients had stage Ⅰ-Ⅱ complications. Three patients had more severe complications(one stage Ⅲ, one stage Ⅳ and one death due to bowel perforation). Two patients suffered from postoperative liver failure according to the 50/50 criteria. None of our patients developed any biliary complication during the ALPPS procedure.CONCLUSION Rescue ALPPS may be an alternative after unsuccessful PVE and could allow previously unresectable patients to reach surgery. Biliary drainage seems to reduce biliary complications. | Charlotte Maulat Antoine Philis Bérénice Charriere Fatima-Zohra Mokrane Rosine Guimbaud Philippe Otal Bertrand Suc Fabrice Muscari | 2017 | World Journal of Clinical Oncology2017，8，4： | 7 |
| 3 | 用法国小麦粉制作中国面条的研究Ⅱ.实验室制作方便面显示文摘选择了 8种典型的法国商品面粉与我国的 5种面条专用粉对比 ,在实验室研究了法国小麦粉制作方便面的适宜性 ,用揉混仪测定制作方便面时的最佳吸水量 ,用粘弹仪测定方便面在烹煮后的物理特性 ,弥补了感官评价的不足 ,法国小麦粉制作的方便面存在的缺陷主要表现在色泽等外观品质上 ,这与法国小麦粉的低加工精度和高出粉率有关 ,尽管法国小麦粉的蛋白质含量较低 ,但具有制作方便面的良好品质 :软硬适中、弹性好、耐咀嚼、不粘、爽口 . | 赵仁勇 J P Leygue 刘长虹 R Bertrand | 2002 | 郑州工程学院学报2002，23，2： | 5 |
| 4 | Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study显示文摘 | Shamir R Mehta Salim Yusuf Ron JG Peters Michel E Bertrand Basil S Lewis Madhu K Natarajan Klas Malmberg Hans-Jürgen Rupprecht Feng Zhao Susan Chrolavicius Ingrid Copland Keith AA Fox | 2001 | The Lancet . 2001 (9281)2001，，9281： | 4 |
| 5 | A longitudinal study of SARS-CoV-2-infected patients reveals a high correlation between neutralizing antibodies and COVID-19 severity显示文摘Understanding the immune responses elicited by SARS-CoV-2 infection is critical in terms of protection against reinfection and,thus,for public health policy and vaccine development for COVID-19.In this study,using either live SARS-CoV-2 particles or retroviruses pseudotyped with the SARS-CoV-2 S viral surface protein(Spike),we studied the neutralizing antibody(nAb)response in serum samples from a cohort of 140 SARS-CoV-2 qPCR-confirmed infections,including patients with mild symptoms and also more severe forms,including those that required intensive care.We show that nAb titers correlated strongly with disease severity and with anti-spike IgG levels.Indeed,patients from intensive care units exhibited high nAb titers;conversely,patients with milder disease symptoms had heterogeneous nAb titers,and asymptomatic or exclusive outpatient-care patients had no or low nAbs.We found that nAb activity in SARS-CoV-2-infected patients displayed a relatively rapid decline after recovery compared to individuals infected with other coronaviruses.Moreover,we found an absence of cross-neutralization between endemic coronaviruses and SARS-CoV-2,indicating that previous infection by human coronaviruses may not generate protective nAbs against SARS-CoV-2.Finally,we found that the D614G mutation in the spike protein,which has recently been identified as the current major variant in Europe,does not allow neutralization escape.Altogether,our results contribute to our understanding of the immune correlates of SARS-CoV-2-induced disease,and rapid evaluation of the role of the humoral response in the pathogenesis of SARS-CoV-2 is warranted. | Vincent Legros Solène Denolly Manon Vogrig Bertrand Boson Eglantine Siret Josselin Rigaill Sylvie Pillet Florence Grattard Sylvie Gonzalo Paul Verhoeven Omran Allatif Philippe Berthelot Carole Pélissier Guillaume Thiery Elisabeth Botelho-Nevers Guillaume Millet Jérôme Morel Stéphane Paul Thierry Walzer François-Loïc Cosset Thomas Bourlet Bruno Pozzetto | 2021 | Cellular & Molecular Immunology2021，18，2： | 3 |
| 6 | Contribution of alpha-fetoprotein in liver transplantation for hepatocellular carcinoma显示文摘Alpha-fetoprotein(AFP) is the main tumor biomarker available for the management of hepatocellular carcinoma(HCC). Although it is neither a good screening test nor an accurate diagnostic tool for HCC, it seems to be a possible prognostic marker. However, its contribution in liver transplantation for HCC has not been fully determined, although its use to predict recurrence after liver transplantation has been underlined by international societies. In an era of organ shortages, it could also have a key role in the selection of patients eligible for liver transplantation. Yet unanswered questions remain. First, the cut-off value of serum AFP above which liver transplantation should not be performed is still a subject of debate. We show that a concentration of 1000 ng/m L could be an exclusion criterion, whereas values of < 15 ng/m L indicate patients with an excellent prognosis whatever the size and number of tumors. Monitoring the dynamics of AFP could also prove useful. However, evidence is lacking regarding the values that should be used. Today, the real input of AFP seems to be its integration into new criteria to select patients eligible for a liver transplantation. These recent tools have associated AFP values with morphological criteria, thus refining pre-existing criteria, such as Milan, University of California, San Francisco, or 'up-to-seven'. We provide a review of the different criteria submitted within the past years. Finally, AFP can be used to monitor recurrence after transplantation, although there is little evidence to support this claim. Future challenges will be to draft new international guidelines to implement the use of AFP as a selection tool, and to determine a clear cut-off value above which liver transplantation should not be performed. | Bérénice Charrière Charlotte Maulat Bertrand Suc Fabrice Muscari | 2016 | World Journal of Hepatology2016，8，21： | 3 |
| 7 | Intensified chemotherapy with ACVBP plus rituximab versus standard CHOP plus rituximab for the treatment of diffuse large B-cell lymphoma (LNH03-2B): an open-label randomised phase 3 trial显示文摘 | Christian Récher Bertrand Coiffier Corinne Haioun Thierry Jo Molina Christophe Fermé Olivier Casasnovas Catherine Thiéblemont André Bosly Guy Laurent Franck Morschhauser Hervé Ghesquières Fabrice Jardin Serge Bologna Christophe Fruchart Bernadette Corront | 2011 | 2011 (9806)2011，，9806： | 2 |
| 8 | Dual Peroxisome Proliferator–Activated Receptor α/δ Agonist GFT505 Improves Hepatic and Peripheral Insulin Sensitivity in Abdominally Obese Subjects显示文摘 | Bertrand Cariou Rémy Hanf Stéphanie Lambert-Porcheron Yassine Za?r Valérie Sauvinet Benoit No?l Laurent Flet Hubert Vidal Bart Staels Martine Laville | 2013 | Diabetes Care2013，，10： | 2 |
| 9 | Folic acid supplementation, MTHFR and MTRR polymorphisms, and the risk of childhood leukemia: the ESCALE study (SFCE)显示文摘 | Alicia Amigou Jérémie Rudant Laurent Orsi Stéphanie Goujon-Bellec Guy Leverger André Baruchel Yves Bertrand Brigitte Nelken Geneviève Plat Gérard Michel Stéphanie Haouy Pascal Chastagner Stéphane Ducassou Xavier Rialland Denis Hémon Jacqueline Clavel | 2012 | Cancer Causes & Control2012，，8： | 2 |
| 10 | Construction and analysis of a microsatellite-based database of European wheat varieties显示文摘 | M. R?der K. Wendehake V. Korzun G. Bredemeijer D. Laborie L. Bertrand P. Isaac S. Rendell J. Jackson R. Cooke B. Vosman M. Ganal | 2002 | Theoretical and Applied Genetics2002，，1： | 2 |
| 11 | Meningeal melanocytoma:Report of a case and a historical comparison显示文摘 | Clarke DB Leblane R Bertrand G | 1998 | J Neurosurg1998，88，1： | 1 |
| 12 | Oxidation-resistant carbon-fiber-reinforced ceramic-matrix composites显示文摘 | BERTRAND S PAILLER R | 1999 | Composites Science and Technology1999，59，： | 1 |
| 13 | Speckle motion artifact under tissue shearing显示文摘 | Maurice R L Bertrand M | 1999 | IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control1999，46，3： | 1 |
| 14 | Sequential administration of camptothecin and etoposide circumvents the antagonistic cytotoxicity of simultaneous drug administration in slowly growing human colon carcinoma HT - 29 cells 显示文摘 | Bertrand R O' ConnorPM KerriganD | 1992 | Eur J Cancer1992，28，45： | 1 |
| 15 | Decreased Fas antigen receptor expression intesticular cell lines derived fl'om polyomavirus large T-antigen transgenic mice 显示文摘 | Lebel M Bertrand R Mes-Masson A M | 1996 | Oncogene1996，12，5： | 1 |
| 16 | The association of smoking status with sleep disturbance, psychological functioning, and pain severity in patients with temporomandibular disorders 显示文摘 | Sde Leeuw R Eisenlohr-Moul T Bertrand P | 2013 | J Orofac Pain2013，27，1： | 1 |
| 17 | The unfolded protein response at the crossroads of cellular life and death during endoplasmic reticulum stress 显示文摘 | Jager R Bertrand M J Gorman AM | 2012 | Biol Cell2012，104，5： | 1 |
| 18 | Wind farm power forecasting 显示文摘 | Haouas N Bertrand P R | 2013 | Mathematical Problems in Engineering2013，，： | 1 |
| 19 | Cambrian-Ordovician shales in the Humber Zone: Thermal maturation and source rock potential显示文摘 | Bertrand R Lavoie D Fowler M | 2003 | Bulletin of Canadian Petroleum Geology2003，51，3： | 1 |
| 20 | Apoptosis of human leukemia HL-60 cells induced to differentiate by phorbol ester treatment显示文摘 | Solary E Bertrand R Pommier Y | 1994 | Leukemia1994，8，5： | 1 |
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