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| 1 | 破裂动脉瘤-栓塞或夹闭疗效相当(英文)显示文摘In the May 2009 issue of The Lancet Neurology,the 5-year follow-up results of the International Subarachnoid Aneurysm Trial(ISAT) were published.The authors concluded that,although the significant difference between coiling and neurosurgical clipping of ruptured intracranial aneurysms in terms of death and severe disability after 1 year has vanished(primary endpoint),coiling should still be favored over neurosurgical clipping because mortality rates significantly favored coiling.In this commentary,it is this particular conclusion that is challenged by combining data from previous ISAT publications with the current 5-year follow-up results.This modified intent-to-treat analysis clearly demonstrates that the significant advantage in terms of mortality in favor of the endovascularly treated patients is no longer present,with a hazard ratio of 0.80 in favor of endovascular treatment(95% confidence interval: 0.60-1.05;P =.10).Therefore,for everyday clinical practice and decision making,coiling and clipping are to be considered equivalent in the long term. | Bakker NA Metzemaekers JD Groen RJ Mooij JJ Van Dijk JM | 2010 | 中华神经外科疾病研究杂志2010，9，3： | 41 |
| 2 | MRI-determined fat content of human liver,pancreas and kidney显示文摘AIM:To assess and correlate the lipid content of various organs in obese subjects and in persons with a normal body weight.METHODS:Magnetic resonance spectroscopy and a previously validated gradient echo magnetic resonance imaging method with Dixon's two point technique were used in this study to quantify fat in liver,pancreas as well as kidney.RESULTS:In 36 volunteers with body mass index(BMI) ranging from 20.0 to 42.9 kg/m2,the median fat content of liver,pancreas and kidney was 2.3%(interquartile range:0.2%-7.8%),2.7%(1.0%-6.5%) and 0.7%(0.1%-1.4%),respectively.BMI and subcutaneous fat correlated significantly with liver and pancreas fat content.We show for the first time the significant correlation of liver and pancreas fat content in healthy controls(r = 0.43,P < 0.01).These observations are related to body weight as measured by BMI and the amount of subcutaneous fat.Kidney fat content is very low and correlates with none of the other fat depots.CONCLUSION:Renal lipid accumulation,unlike the coupled accumulations of fat in liver and pancreas,is not observed in obese subjects.Unlike suggestions made in previous studies,renal lipid accumulation appears not to be involved in the pathogenesis of renal disease in humans. | Paul E Sijens Mireille A Edens Stephan JL Bakker Ronald P Stolk | 2010 | World Journal of Gastroenterology2010，16，16： | 14 |
| 3 | 焦炭特性及其在高炉下部的变化过程显示文摘气化、石墨化和溶解是影响焦炭从高炉软熔带至炉缸间行为的三个主要过程。过去几年在一些专题项目中对这些过程进行了研究。简要叙述并讨论了这些过程的相互作用及其与焦炭特性的关系。对焦炭的气化反应进行了实验室测试研究,用以评价高炉条件下焦炭的特性。用高炉条件下的气化测试装置测试了几种焦炭试样,考查的质量指标包括反应性、结构变化和强度等。用实际尺寸的焦炭块对块状焦炭试样的高温行为进行了评估,将不同种类的焦炭试样加热到2 000℃,以鉴别其在高温下的行为。高温下焦炭将发生石墨化,对高温反应后的强度进行了评定,并作了显微观察,发现了一些现象和组织结构的变化。焦炭与液态渣铁相互作用的研究结果对焦炭在高炉下部的行为有了更好的理解。通过试验研究了焦炭抗液态铁水溶解的性能,对入炉前的焦炭和经高温反应的焦炭分别进行了试验。分析讨论了焦炭的抗气化、抗石墨化和抗铁水溶解性能与其结构、化学成分和强度的关系。 | B van der Velden C J Atkinson T Bakker J R H Stuurwold G J Tijhuis 徐万仁 | 2014 | 世界钢铁2014，，2： | 11 |
| 4 | The Measurement of Engagement and Burnout: A Two Sample Confirmatory Factor Analytic Approach显示文摘 | Wilmar B. Schaufeli Marisa Salanova Vicente González-romá Arnold B. Bakker | 2002 | Journal of Happiness Studies2002，，1： | 10 |
| 5 | DYNAMIC RESOURCE ALLOCATION FOR EFFICIENT PATIENT SCHEDULING: A DATA-DRIVEN APPROACH显示文摘有效职员 rostering 并且遇见门诊病人需求的耐心的安排是一项很复杂、动态的任务。由于受欢迎的变化和专家可获得性,专家分配一定很灵活、非近视。医药专家典型地在亚专门化被限制,服务几个病人组织并且是在对诊所和操作空间的耐心的访问的链的关键资源(或) 。克服一个近视看法一次离开安排的约会,当分配关键资源到不同的耐心的组时,我们通过耐心的约会的链探讨耐心的流动。我们在场到花名同活动和病人的专家的自动分配的一条新、数据驱动的算法的途径组织。由他们的很自然,简化数学模型不能捕获对被建模的系统特征的复杂性。在我们的途径,到他们的日常活动的专家的分配对过去和现在的关键资源可获得性,以及到过去的资源分配灵活、应答。在花名同活动的可变性活跃地被最小化,以便提高供应链流动。与用实验数据的申请盒子的分离事件的模拟,我们说明我们的途径怎么改进耐心的服务水平(SL,病人的百分比服务了在时间上) 象一样等待时间(天) ,没有在资源能力的变化。 | Monique Bakker Kwok-Leung Tsui | 2017 | Journal of Systems Science and Systems Engineering2017，26，4： | 8 |
| 6 | Systematic review: The placebo effect of psychological interventions in the treatment of irritable bowel syndrome显示文摘AIM To determine the placebo response rate associated with different types of placebo interventions used in psychological intervention studies for irritable bowel syndrome. METHODS Randomized controlled trials comparing psychological interventions(stress management/relaxation therapy(cognitive) behavioral therapy, short-term psychodynamic therapy, and hypnotherapy) for the treatment of adult patients with irritable bowel syndrome(IBS) diagnosed with the Manning or Rome criteria with an adequate placebo control treatment and reporting data on IBS symptom severity were identified by searching Pub Med, Embase, the Cochrane Library, CINAHL and Psyc INFO databases. Full-text articles that were written in English and published between 1966 and February 2016 in peer-reviewed journals were selected for the present review. Placebo interventions were considered to be adequate if the number of sessions and the amount of time spent with the therapist were the same as in the active treatment. The placebo response rate(PRR) was computed for IBS symptom severity(primary outcome measure) as well as for anxiety, depression and quality of life(secondary outcome measures). RESULTS Six studies, with a total of 555 patients met the inclusion criteria. Four studies used an educational intervention, whereas two studies used a form of supportive therapy as the placebo intervention. The PRR for IBS symptom severity ranged from 25% to 59%, with a pooled mean of 41.4%. The relative PRR for the secondary outcome measures ranged from 0% to 267% for anxiety, 6% to 52% for depression 20% to 125% for quality of life. The PRR associated with pharmacological treatments, treatment with dietary bran and complementary medicine ranged from 37.5% to 47%. Contrary to our expectations, the PRR in studies on psychological interventions was comparable to that in studies on pharmacological, dietary and alternative medical interventions.CONCLUSION The PRR is probably determined to a larger extent by patient-related factors, such as expectations and desire for the treatment to be effective, than the content of the placebo intervention. | Carla E Flik Laura Bakker Wijnand Laan Yanda R van Rood André JPM Smout Niek J de Wit | 2017 | World Journal of Gastroenterology2017，23，12： | 7 |
| 7 | PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses显示文摘 | Shaun Purcell Benjamin Neale Kathe Todd-Brown Lori Thomas Manuel A.R. Ferreira David Bender Julian Maller Pamela Sklar Paul I.W. de Bakker Mark J. Daly Pak C. Sham | 2007 | The American Journal of Human Genetics2007，，3： | 5 |
| 8 | The dynamics of color signals in male threespine sticklebacks Gasterosteus aculeatus显示文摘 | Meike HIERMES Ingolf P. RICK Marion MEHLIS Theo C. M. BAKKER | 2016 | Current Zoology2016，62，1： | 4 |
| 9 | 环境中的药物——LC-MS/MS分析地表水和地下水显示文摘 | Alida(Linda)AM Stolker Willem Niesing Frank Bakker Johanna(Ans)FM Versteegh Elbert A Hogendoorn Udo A Th Brinkman | 2007 | 环境化学2007，26，4： | 4 |
| 10 | 超超临界火电厂锅炉用材的开发显示文摘传统锅炉/蒸气轮机燃矿型火电厂的发电效率主要取决于蒸气温度和压力。自20世纪70年代发生能源危机以来,提高蒸气温度和压力一直是全球范围的研究热点。近年来,对CO2排放量的限制是促进发电效率提高的又一重要原因。目前,大多数燃矿型火电厂的蒸气温度在600℃左右,这表明,蒸气温度在30年内提高了近60℃。预计在未来30年内,蒸气温度有望再提高50~100℃。主要的技术保障是开发更高强度的高温材料,以抵抗更高的温度和压力。美国电力研究所(EPRI)对用于超超临界火力发电厂(先进锅炉/汽轮机火电厂)的材料技术发展现状进行了综合调查。结果表明:商品化的用于厚壁构件的高强铁素体(9~12)Cr钢的最高使用温度达620℃。对两种试验阶段的12Cr铁素体钢的初步研究显示,可以在650℃的温度条件下长期服役,但尚需更多数据加以证实。应用于过热器和再热器的高级别奥氏体不锈钢的最高服役温度为650℃,最高甚至可达700℃。迄今为止,上述钢种尚未获得美国机械工程师协会(ASME)认证。对于锅炉水冷壁顶排管,由于管内压力在24MPa以上,需采用更高强度级别的材料。日前,一种牌号为T23的含5/2 Cr的高强钢通过了ASME认证,成为较好的候选材料。 | R Viswanathan(美) W T Bakker(美) 钱余海(译) 齐慧滨(校) | 2007 | 世界钢铁2007，7，2： | 3 |
| 11 | PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses显示文摘 | Shaun Purcell Benjamin Neale Kathe Todd-Brown Lori Thomas Manuel A.R. Ferreira David Bender Julian Maller Pamela Sklar Paul I.W. de Bakker Mark J. Daly Pak C. Sham | 2007 | The American Journal of Human Genetics2007，，3： | 3 |
| 12 | Burnout and work engagement among teachers显示文摘 | Jari J. Hakanen Arnold B. Bakker Wilmar B. Schaufeli | 2005 | Journal of School Psychology2005，，6： | 3 |
| 13 | Long-term changes in biological soil crust cover and composition显示文摘Introduction:Communities change over time due to disturbances,variations in climate,and species invasions.Biological soil crust communities are important because they contribute to erosion control and nutrient cycling.Crust types may respond differently to changes in environmental conditions:single-celled organisms and bryophytes quickly recover after a disturbance,while lichens are slow growing and dominate favorable sites.Community change in crusts has seldom been assessed using repeated measures.For this study,we hypothesized that changes in crust composition were related to disturbance,topographic position,and invasive vegetation.Methods:We monitored permanent plots in the Columbia Basin in 1999 and 2010 and compared changes in crust composition,cover,richness,and turnover with predictor variables of herbivore exclosure,elevation,heat load index,time since fire,presence of an invasive grass,and change in cover of the invasive grass.Results:Bryophytes were cosmopolitan with high cover.Dominant lichens did not change dramatically.Indicator taxa differed by monitoring year.Bryophyte and total crust cover declined,and there was lower turnover outside of herbivore exclosures.Lichen cover did not change significantly.Plots that burned recently had high turnover.Increase in taxon richness was correlated with presence of an invasive grass in 1999.Change in cover of the invasive grass was positively related to proportional loss and negatively related to gain.Conclusions:Composition and turnover metrics differed significantly over 11 years,though cover was more stable between years.This study can be a baseline for assessing change in crust composition due to anthropogenic influences. | Eva Dettweiler-Robinson Jeanne M Ponzetti Jonathan D Bakker | 2013 | Ecological Processes2013，2，1： | 3 |
| 14 | 地理信息系统在四川省麻风防治中的应用显示文摘目的:探索四川省新发麻风病例的空间时间集群分布及GIS技术在麻风防治中的应用。方法:采用回顾性描述性研究方法,应用GIS技术对麻风流行病学数据,包括病例发现率、患病率、新发病例数和新发病例中2级畸残率等进行分析。结果:2002-2008年发现3个统计学意义的短时限新发病例空间时间群集分布,最大可能的集群分布于凉山彝族自治州;部分相对低流行地区新发病例2级畸残率显著高于全省水平。结论:GIS技术作为一种先进应用工具,为麻风流行状况分析、合理资源分配、项目管理评估等提供新的手段。 | 刘杨英 宁湧 Mirjam Bakker 熊俊浩 | 2011 | 中国麻风皮肤病杂志2011，27，4： | 2 |
| 15 | The fibrosis marker galectin‐3 and outcome in the general population显示文摘 | R. A. de Boer D. J. van Veldhuisen R. T. Gansevoort A. C. Muller Kobold W. H. van Gilst H. L. Hillege S. J. L. Bakker P. van der Harst | 2011 | Journal of Internal Medicine2011，，1： | 2 |
| 16 | Blood lactate monitoring in critically ill patients: A systematic health technology assessment显示文摘 | Tim C. Jansen Jasper van Bommel Jan Bakker | 2009 | Critical Care Medicine2009，，10： | 2 |
| 17 | Effect of rumen-protected choline on performance, blood metabolites, and hepatic triacylglycerols of periparturient dairy cattle显示文摘 | R.L.G. Zom J. van Baal R.M.A. Goselink J.A. Bakker M.J. de Veth A.M. van Vuuren | 2011 | Journal of Dairy Science2011，，8： | 2 |
| 18 | Relationship between soil chemical factors and grassland diversity显示文摘 | F. Janssens A. Peeters J.R.B. Tallowin J.P. Bakker R.M. Bekker F. Fillat M.J.M. Oomes | 1998 | Plant and Soil1998，，1： | 2 |
| 19 | Endoscopic transluminal necrosectomy in necrotising pancreatitis: a systematic review显示文摘 | Sandra Brunschot Paul Fockens Olaf J. Bakker Marc G. Besselink Rogier P. Voermans Jan-Werner Poley Hein G. Gooszen Marco Bruno Hjalmar C. Santvoort | 2014 | Surgical Endoscopy2014，，5： | 2 |
| 20 | Staged multidisciplinary step‐up management for necrotizing pancreatitis显示文摘 | D. W. da Costa D. Boerma H. C. van Santvoort K. D. Horvath J. Werner C. R. Carter T. L. Bollen H. G. Gooszen M. G. Besselink O. J. Bakker | 2014 | Br J Surg2014，，1： | 2 |
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