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| 1 | Recent advances on the association of apoptosis in chronic non healing diabetic wound显示文摘Generally, wounds are of two categories, such as chronic and acute. Chronic wounds takes time to heal when compared to the acute wounds. Chronic wounds include vasculitis, non healing ulcer, pyoderma gangrenosum, and diseases that cause ischemia. Chronic wounds are rapidly increasing among the elderly population with dysfunctional valves in their lower extremity deep veins, ulcer, neuropathic foot and pressure ulcers. The process of the healing of wounds has several steps with the involvement of immune cells and several other cell types. There are many evidences supporting the hypothesis that apoptosis of immune cells is involved in the wound healing process by ending inflammatory condition. It is also involved in the resolution of various phases of tissue repair. During final steps of wound healing most of the endothelial cells, macrophagesand myofibroblasts undergo apoptosis or exit from the wound, leaving a mass that contains few cells and consists mostly of collagen and other extracellular matrix proteins to provide strength to the healing tissue. This review discusses the various phases of wound healing both in the chronic and acute wounds especially during diabetes mellitus and thus support the hypothesis that the oxidative stress, apoptosis, connexins and other molecules involved in the regulation of chronic wound healing in diabetes mellitus and gives proper understanding of the mechanisms controlling apoptosis and tissue repair during diabetes and may eventually develop therapeutic modalities to fasten the healing process in diabetic patients. | Awadhesh K Arya Richik Tripathi Santosh Kumar Kamlakar Tripathi | 2014 | World Journal of Diabetes2014,5,6: | 14 |
| 2 | Genome-Wide Organization and Expression Profiling of the NAC Transcription Factor Family in Potato (Solanum tuberosum L.)显示文摘 | Anil Kumar Singh Vishal Sharma Awadhesh Kumar Pal Vishal Acharya Paramvir Singh Ahuja | 2013 | DNA Research2013,,4: | 2 |
| 3 | Edge superconductivity in multilayer WTe2 Josephson junction显示文摘WTe2,as a type-ⅡWeyl semimetal,has 2D Fermi arcs on the(O01)surface in the bulk and 1D helical edge states in its monolayer.These features have recently attracted wide attention in condensed matter physics.However,in the intermediate regime between the bulk and monolayer,the edge states have not been resolved owing to its closed band gap which makes the bulk states dominant.Here,we report the signatures of the edge superconductivity by superconducting quantum interference measurements in multilayerWTe2 Josephson junctions and we directly map the localized supercurrent.In thickWTe(~60nm),the supercurrent is uniformly distributed by bulk states with symmetricJosephson effect(|Ic+(B)|=|Ic^-(B)|).In thin WTe2(10 nm),however,the supercurrent becomes confined to the edge and its width reaches up to 1.4μm and exhibits non-symmetric behavior|Ic^+(B)|≠|Ic^-(B)|.The ability to tune the edge domination by changing thickness and the edge superconductivity establishes WTez as a promising topological system with exotic quantum phases and a rich physics. | Ce Huang Awadhesh Narayan Enze Zhang Xiaoyi Xie Linfeng Ai Shanshan Liu Changjiang Yi Youguo Shi Stefano Sanvito Faxian Xiu | 2020 | National Science Review2020,7,9: | 2 |
| 4 | High temperature fiber optic laser induced breakdown spectroscopy sensor for analysis of molten alloy constituents显示文摘 | Awadhesh K Rai | 2002 | Review of Scientific Instruments2002,763,10: | 1 |
| 5 | Specifying Mobile Network Using a WP-like Formal Approach显示文摘 | Awadhesh K S Umesh G Anup K B | 2005 | Revista Colombiana de Computer2005,6,2: | 1 |
| 6 | Decal hone matrix as a local antibiotic delivery vehicle in a MRSA-irdected hone model: an experimetltal study显示文摘 | Saraf Shyam Yadav Awadhesh Nagwani San~osh | 2010 | Indian Journal of Ortho- paedics2010,44,3: | 1 |
| 7 | High temperature fiber optic laser-induced breakdown spectroscopy sensor for analysis of molten alloy constituents显示文摘 | Awadhesh K R Fang Y Y Jagdish P S | 2002 | Review of Scientific Instruments2002,73,10: | 1 |
| 8 | A clinicopathological, immunohistochemical and neuroradiological study of eight patients with central neurocytoma显示文摘 | Sushila Jaiswal Mukul Vij Dinesh Rajput Anant Mehrotra Awadhesh Kumar Jaiswal Arun Kumar Srivastava Sanjay Behari Narendra Krishnani | 2010 | Journal of Clinical Neuroscience2010,,3: | 1 |
| 9 | The random amplified polymorphicDNA(RAPD)assay and related techniques applied to genotoxicityand carcinogenesis studies:a critical review显示文摘 | Franck A A Awadhesh N J | 2006 | Mutation Re-search2006,613,23: | 1 |
| 10 | Metabolic and cardiovascular benefits with combination therapy of SGLT-2 inhibitors and GLP-1 receptor agonists in type 2 diabetes显示文摘Both GLP-1 receptor agonists(GLP-1RA)and SGLT-2 inhibitors(SGLT-2I)are newer classes of anti-diabetic agents that lower HbA1c moderately and decrease body weight and systolic blood pressure(SBP)modestly.Combination therapy with GLP-1RA plus SGLT-2I have shown a greater reduction in HbA1c,body weight,and SBP compared to either agent alone without any significant increase in hypoglycemia or other side effects.Since several agents from each class of these drugs have shown an improvement in cardiovascular(CV)and renal outcomes in their respective cardiovascular outcome trials(CVOT),combination therapy is theoretically expected to have additional CV and renal benefits.In this comprehensive opinion review,we found HbA1c lowering with GLP-1RA plus SGLT-2I to be less than additive compared to the sum of HbA1c lowering with either agent alone,although body weight lowering was nearly additive and the SBP lowering was more than additive.Our additional meta-analysis of CV outcomes with GLP1RA plus SGLT-2I combination therapy from the pooled data of five CVOT found a similar reduction in three-point major adverse cardiovascular events compared to GLP-1RA or SGLT-2I alone,against placebo.Interestingly,a greater benefit in reduction of heart failure hospitalization with GLP-1RA plus SGLT-2I combination therapy was noted in the pooled meta-analysis of two randomized controlled trials.Future adequately powered trials can confirm whether additional CV or renal benefit is truly exerted by GLP-1RA plus SGLT-2I combination therapy. | Awadhesh Kumar Singh Ritu Singh | 2022 | World Journal of Cardiology2022,14,6: | 1 |
| 11 | Genotoxic,cytotoxic,developmental and survival effects of tritiated water in the early Jife stages of the marine mollusc,Mytius edulis显示文摘 | JOSEPHINE A H FRANCK A A AWADHESH N J | 2005 | Aquatic Toxicology2005,74,: | 1 |
| 12 | Singh, Arel Weisburg, Parametric study of a fiberoptic laser-induced breakdown spectroscopy probe for analysis of aluminum alloys显示文摘 | Awadhesh K Rai Hansheng Zhang Fang Yu Yueh Jagdish P | 2001 | Spectrochimica Acta Part B2001,56,: | 1 |
| 13 | Genotoxicological studies in aquatic organisms: an overview显示文摘 | Awadhesh N J | 2004 | Mutation Res2004,552,: | 1 |
| 14 | Hydroxyl radicals (<ce:glyph name='rad'/>OH) are associated with titanium dioxide (TiO 2 ) nanoparticle-induced cytotoxicity and oxidative DNA damage in fish cells显示文摘 | James F. Reeves Simon J. Davies Nicholas J.F. Dodd Awadhesh N. Jha | 2007 | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis2007,,1: | 1 |
| 15 | E- valuation of the random amplified polymorphic DNA (RAPD) assay for detection of DNA damage and mutations 显示文摘 | Franck A Atienzar Paola Venier Awadhesh N Jha | 2002 | Muta- tion research/Genetic Toxicology and Environmental Mutagene- sis2002,521,: | 1 |
| 16 | Successfully treated synchronous double malignancy of the breast and esophagus : a case report 显示文摘 | Abhishek S Ishwar CK Awadhesh KD | 2010 | J Med Case Reports2010,4,6: | 1 |
| 17 | Influence of gamma rays and ethyl methane sulphonate (EMS)on the levels of phytic acid, raffinose family oligosaccharides and antioxidants in soybean seeds of different genotypes显示文摘 | Awadhesh K Varun K Lal S K | 2015 | Journal of Plant Biochemistry Biotechnology2015,24,2: | 1 |
| 18 | Specifying mobile network using a wp-like formal approach 显示文摘 | Awadhesh Kumar Singh Umesh Ghanekar Anup Kumar Bandyopadhyay | 2005 | Revista Colombiana de Computacion2005,6,2: | 1 |
| 19 | Relook at DPP-4 inhibitors in the era of SGLT-2 inhibitors显示文摘SGLT-2 inhibitors(SGLT-2Is)have significantly improved cardio-renal outcomes and are preferred agents in people with cardiovascular diseases,heart failure,and diabetic kidney disease.Similarly,GLP-1 receptor agonists(GLP-1RAs)have significantly improved atherosclerotic cardiovascular outcomes.To this end,DPP-4 inhibitors(DPP-4Is)are cardiac-neutral drugs.While long-acting GLP-1RAs have shown a favorable HbA1c lowering compared to DPP-4Is,there is no clinically meaningful HbA1c lowering difference between SGLT-2Is vs DPP-4Is.Moreover,the glucose-lowering potential of SGLT-2Is gets compromised with a progressive decline in renal functions,unlike DPP-4Is.Furthermore,the HbA1c lowering potential of DPP-4Is is favorable in people with T2DM having a modest baseline HbA1c(8.0%-8.5%)compared with SGLT-2Is which lowers HbA1c larger in a background of higher baseline HbA1c(>8.5%-9.0%).These findings suggest that the role of DPP-4Is in the management of type 2 diabetes mellitus cannot be completely ignored even in the era of SGLT-2Is. | Awadhesh Kumar Singh Ritu Singh | 2022 | World Journal of Diabetes2022,13,6: | 0 |
| 20 | Acoustoelectric effect in semiconductor materials and devices显示文摘This paper reviews the studies on acoustoelectric effectin extrinsic semiconductor materials used in various scientific and othermeasurements.A historical review of earlier findings is given with specialreference to associated mechanisms.Acoustoelectric studies in solid statedevioes require further attention and the work done in this area is alsodiscussed. | V.R.SINGH Awadhesh PRASAD | 1990 | Chinese Journal of Acoustics1990,9,3: | 0 |