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541篇 您的检索式:作者名="Angelo M"
    题名 作者 年代 出处 被引量
1一种miRNA标记在胶质瘤侵袭性表型的确定与预后评估中的价值(英文)显示文摘Gliomas represent a disparate group of tumours for which there are to date no cure. Thus,there is a recognized need for new diagnostic and therapeutic approaches based on increased understanding of their molecular nature. We performed the comparison of the microRNA( miRNA) profile of 8 WHO grade II gliomas and 24 higher grade tumours( 2 WHO grade III and 22 glioblastomas) by using the Affymetrix Gene Chip miRNA Array v. 1. 0. A relative quantification method( RT-q PCR) with standard curve was used to confirm the 22 miRNA signature resulted by array analysis. The prognostic performances of the confirmed miRNAs were estimated on the Tumor Cancer Genome Atlas( TCGA) datasets. We identified 22 miRNAs distinguishing grade II gliomas from higher grade tumours.RT-q PCR confirmed the differential expression in the two patients' groups for 13 out of the 22 miRNAs. The analysis of the Glioblastoma Multiforme( GBM) and Lower Grade Glioma( LGG) datasets from TCGA demonstrated the association with prognosis for 6 of those miRNAs. Moreover,in the GBM dataset miR-21 and miR-210 were predictors of worse prognosis in both univariable and multivariable Cox regression analyses( HR 1. 19,P = 0. 04,and HR 1. 18,P = 0. 029 respectively). Our results support a direct contribution of miRNAs to glioma cancerogenesis and suggest that miR-21 and miR-210 may play a role in the aggressive clinical behaviour of glioblastomas.Barbano R Palumbo O Pasculli B Galasso M Volinia S D'Angelo V Icolaro N Coco M Dimitri L Graziano P Copetti M Valori VM Maiello E Carella M Fazio VM Parrella P 2014中华神经外科疾病研究杂志2014,13,5:6
2Predicted Effects of Treatment for HCV Infection Vary Among European Countries显示文摘Sylvie Deuffic–Burban Pierre Deltenre Maria Buti Tommaso Stroffolini Julie Parkes Nikolai Mühlberger Uwe Siebert Christophe Moreno Angelos Hatzakis William Rosenberg Stefan Zeuzem Philippe Mathurin 2012Gastroenterology2012,,4:2
3Interplay between SOX9, β-catenin and PPARγ activation in colorectal cancer显示文摘Anna Panza Valerio Pazienza Maria Ripoli Giorgia Benegiamo Annamaria Gentile Maria Rosaria Valvano Bartolomeo Augello Giuseppe Merla Clelia Prattichizzo Francesca Tavano Elena Ranieri Pierluigi di Sebastiano Manlio Vinciguerra Angelo Andriulli Gianluigi M 2013BBA - Molecular Cell Research2013,,8:2
4Adenosine administration produces an antidepressant-like effect in mice: evidence for the involvement of A1 and A2A recep- tom显示文摘MANIYKTA P K ANGELO O R MATHEUS M R 2004Nemvscience Letters2004,355,:1
5Assessing Public-privateResearch Collaboration:is it Possible to Compare University Per-formance显示文摘Abramo G D'Angelo C A Solazzi M 2010Scientometrics2010,84,1:1
6Overexpression of hypoxia-inducible factor 1α in common human cancers and their metastasis显示文摘Zhong H Angelo M Laughner D 1999Cancer Res1999,8,59:1
7Relations of daily hassles with bothanxious and depressed mood in students 显示文摘D'ANGELO B WIERZBIEKI M 2003Psychol Rep2003,9,2:1
8Lateral ventricle tumors: surgical strategies according to tumor origin and development-a series of 72 cases 显示文摘D'angelo VA Galarza M Catapano D 2008Neurosurgery2008,62,613:1
9Identification of lipoxygenase linoleate decomposition products by direct gas chromatography-mass spectrometry显示文摘Angelo A J Legendre M G Dupuy H P 1980Lipids1980,15,:1
10Proposed refinement to the superpave high temperature specification parameter for performance graded binder 显示文摘Bouldin M G Dongre R D'Angelo J 2001Transportation Research Record2001,,1766:1
11Current analytical methods for trichothecene my- cotoxins in cereals 显示文摘Veronica M T Lattanzio Michelangelo Pascale Angelo Visconti 2009Trends in Analytical Chemistry2009,28,6:1
12Towards gene therapy for deafness显示文摘Di Domenico M Ricciardi C Martone T Mazzarella N. Cassandro C. Chiarella G. D'Angelo L. Cassandro E 0,,:1
13Efficacy and limitations of triticale as a nitrogen catch crop in a mediterranean environment显示文摘Angelo Rodrigues M Coutinho J Fernando M 2002European Journal of Agronomy2002,17,15:1
14Hydrodynamical modeling of charge carrier transport in semiconductors显示文摘Angelo M A Vittorio R 2000Overviews and Tutorials2000,35,:1
15Abnormal regulation of DNA-methyl transferase expression during colorectal carcinogensis显示文摘 Demarzo Valeriel 1999Cancer Research1999,59,16:1
16The molecular pathogenesis of small cell lung cancer显示文摘D' Angelo S P Pietanza M C 2010Zhongguo Fei Ai Za Zhi2010,13,11:1
17Hypoxic reperfusion of the ischemic heart and oxygen radical generation显示文摘Angelos MG Kutala VK Torres CA He G Stoner JD Mohammad M 2006Am J Physiol Heart Circ Physiol2006,290,:1
18Quantitative Analysis of XANES Spectra of Disordered Systems Based on Molecular Dynamics显示文摘Roscioni O M D' Angelo P Chillemi G 2005J Synchrotron Rad2005,121,:1
19Flavonoids: old and new aspects of a class of natural therapeutic drugs 显示文摘GIULIA D C NICOLA M ANGELO A I 1999Life Sciences1999,65,4:1
20Anticoagulant and aspirin prophylaxis for preventing thromboembolism after major gynecological surgery显示文摘Oates-Whitehead R M DAngelo A Mol B 2004Br J Perioper Nurs2004,14,7:1
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