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	题名	作者	年代	出处	被引量
1	一种miRNA标记在胶质瘤侵袭性表型的确定与预后评估中的价值(英文)显示文摘Gliomas represent a disparate group of tumours for which there are to date no cure. Thus,there is a recognized need for new diagnostic and therapeutic approaches based on increased understanding of their molecular nature. We performed the comparison of the microRNA( miRNA) profile of 8 WHO grade II gliomas and 24 higher grade tumours( 2 WHO grade III and 22 glioblastomas) by using the Affymetrix Gene Chip miRNA Array v. 1. 0. A relative quantification method( RT-q PCR) with standard curve was used to confirm the 22 miRNA signature resulted by array analysis. The prognostic performances of the confirmed miRNAs were estimated on the Tumor Cancer Genome Atlas( TCGA) datasets. We identified 22 miRNAs distinguishing grade II gliomas from higher grade tumours.RT-q PCR confirmed the differential expression in the two patients' groups for 13 out of the 22 miRNAs. The analysis of the Glioblastoma Multiforme( GBM) and Lower Grade Glioma( LGG) datasets from TCGA demonstrated the association with prognosis for 6 of those miRNAs. Moreover,in the GBM dataset miR-21 and miR-210 were predictors of worse prognosis in both univariable and multivariable Cox regression analyses( HR 1. 19,P = 0. 04,and HR 1. 18,P = 0. 029 respectively). Our results support a direct contribution of miRNAs to glioma cancerogenesis and suggest that miR-21 and miR-210 may play a role in the aggressive clinical behaviour of glioblastomas.	Barbano R Palumbo O Pasculli B Galasso M Volinia S D'Angelo V Icolaro N Coco M Dimitri L Graziano P Copetti M Valori VM Maiello E Carella M Fazio VM Parrella P	2014	中华神经外科疾病研究杂志2014，13，5：	6
2	Atherosclerosis severity but not undiagnosed diabetes predicts new car- diovascular events of subjects in secondary cardiovascular prevention 显示文摘	Rizza S Copetti M Cardellini M	2012	Atherosclerosis2012，223，2：	1
3	Arterial endothelial dysfunction and idiopath ic deep venous thrombosis显示文摘	Mazzoccoli G Grilli M Ferrandino F Copetti M Fontana A Pellegrini F	2011	J Bioi Regul Homeost Agents2011，25，：	1
4	Numerical solution of a thermoviscoelastic contact problem by a penalty method显示文摘	Copetti M I M French D A	2003	SIAM Journal on Numerical Analysis2003，41，4：	1
5	Numerical solution of a thermoviscoelastic contact problem by a penalty method显示文摘	Copetti M I M French D A	2003	SIAM Journal on Numerical Analysis2003，41，4：	1
6	Finite element approximation to a contact problem for a nonlinea thermoviscoelastic beam显示文摘	Copetti M I M Fernandez J R	2011	J Math Anal Appl2011，383，：	1
7	Numerical solution of a thermoviscoelastic contact problem by a penalty method显示文摘	COPETTI M I M FRENCH D A	2003	SIAM Journal on Numerical Analysis2003，41，4：	1
8	High specificity of quantitative methylationspecific PCR analysis for MGMT promoter hypermethylation detection in gliomas显示文摘	Parrella P La Torre A Copetti M	2009	J Biomed Biotechnol2009，2009，53：	1
9	Comparison between real-time quantitative PCR detection of HER2 mRNA copy number in periph- eral blood and ELISA of serum HER2 protein for determining HER2 status in breast cancer patients 显示文摘	Strati A Parrella P Copetti M	2009	Cell Oncol2009，31，3：	1
10	A linear mixedmodel approach to compare the evolution of multiple bio-logical rhythms 显示文摘	Fontana A Copetti M Mazzoccoli G	2013	Statistics in Medicine2013，32，7：	1
11	Experiments with micro-fin tube in single phase显示文摘	COPETTI J B MACAGNAN M H SOUZA D	2004	Int J Refrigeration2004，27，8：	1
12	Metabo\|omics signature im- t proves the prediction of cardiovascular events in elderly subjects 显示文摘	Rizza S Copetti M Rossi C	2014	Atherosclerosis2014，232，2：	1
13	Finite element approximation to a contact problem in linear thermo-elasticity显示文摘	Copetti M I M	1999	Mathematics of Computation1999，68，227：	1
14	Numerical solution of a thermoviscoelastic contact problem by a penalty method显示文摘	Copetti M I M French D A	2003	SIAM Journal on Numerical Analysis2003，41，4：	1
15	Atherosclerosis severity but not undiagnosed diabetes predicts new cardiovascular events of subjects in secondary cardiovascular prevention 显示文摘	Rizza S Copetti M Cardellini M	2012	Atherosclerosis2012，223，2：	1
16	Stage dependent destructuration of neuro-endocrine-immune system components in lung cancer patients显示文摘	Mazzoccoli G Fontana A Copetti M	2011	Biomed Pharmacother2011，65，1：	1
17	Numericalanalysis of an adsorption dynamic model at the air-water interface显示文摘	Copetti M I M Ferndndez J R Mufliz M C	2015	Journal of Computational and Applied Mathematics2015，281，：	1
18	Metabolomics signature improves the prediction of cardiovascular events in elderly subjects显示文摘	RIZZA S COPETTI M ROSSI C	2014	Atherosclerosis2014，232，2：	1
19	miRNA expression profiles identify drivers in colorectal and pancreatic cancers 显示文摘	PIEPOLI A TAVANO F COPETTI M	2012	PLoS One2012，7，33：	1
20	Relationship between ADIPOQ gene, circulating high molecular weight adiponectin and al- buminuria in individuals with normal kidney function: evidence from a family-based study显示文摘	Menzaghi C De Cosmo S Copetti M	2011	Diabetologia2011，，54：	1

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