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24篇 您的检索式：作者名="Fazio VM"

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	题名	作者	年代	出处	被引量
1	一种miRNA标记在胶质瘤侵袭性表型的确定与预后评估中的价值(英文)显示文摘Gliomas represent a disparate group of tumours for which there are to date no cure. Thus,there is a recognized need for new diagnostic and therapeutic approaches based on increased understanding of their molecular nature. We performed the comparison of the microRNA( miRNA) profile of 8 WHO grade II gliomas and 24 higher grade tumours( 2 WHO grade III and 22 glioblastomas) by using the Affymetrix Gene Chip miRNA Array v. 1. 0. A relative quantification method( RT-q PCR) with standard curve was used to confirm the 22 miRNA signature resulted by array analysis. The prognostic performances of the confirmed miRNAs were estimated on the Tumor Cancer Genome Atlas( TCGA) datasets. We identified 22 miRNAs distinguishing grade II gliomas from higher grade tumours.RT-q PCR confirmed the differential expression in the two patients' groups for 13 out of the 22 miRNAs. The analysis of the Glioblastoma Multiforme( GBM) and Lower Grade Glioma( LGG) datasets from TCGA demonstrated the association with prognosis for 6 of those miRNAs. Moreover,in the GBM dataset miR-21 and miR-210 were predictors of worse prognosis in both univariable and multivariable Cox regression analyses( HR 1. 19,P = 0. 04,and HR 1. 18,P = 0. 029 respectively). Our results support a direct contribution of miRNAs to glioma cancerogenesis and suggest that miR-21 and miR-210 may play a role in the aggressive clinical behaviour of glioblastomas.	Barbano R Palumbo O Pasculli B Galasso M Volinia S D'Angelo V Icolaro N Coco M Dimitri L Graziano P Copetti M Valori VM Maiello E Carella M Fazio VM Parrella P	2014	中华神经外科疾病研究杂志2014，13，5：	6
2	Sperm cells as vectors for introducing foreign DNA into eggs:Genetic transformation of mice显示文摘	Lavitrano M Camaioni A Fazio VM	1989	Cell1989，，57：	1
3	Immune response at birth, long-term immune memory and 2 years follow- up after in-utero anti-HBV DNA immunization 显示文摘	Fazio VM Ria F Franco E	2004	Gene Ther2004，11，6：	1
4	Sperm cells as vector for introduction foreign DNA into eggs:genetic transformation of mice显示文摘	Lavitrano M Camaioni A Fazio VM	1989	Cell1989，57，：	1
5	Sperm cell as vectors for introducing foreign DNA into eggs:gentic transformation of mice显示文摘	Lavitrano M Camaioni A Fazio VM	1989	Cell1989，57，：	1
6	Sperm cell as vectors far introducing foreign DNA into eggs : genetic transformation of mice 显示文摘	Lavitrano M Camaloni A Fazio VM	1989	Cell1989，57，3：	1
7	Sperm cells as vectors for introducing foreign DNA into eggs: genetic transformation of mice显示文摘	Lavitrano M Camaioni A Fazio VM	1989	Cell1989，57，5：	1
8	DNA vaccines: Develo?ping new strategies against cancer 显示文摘	Fioretti D Iurescia S Fazio VM	2010	J Biomed Biotechnol2010，2010，17：	1
9	Electroporation in DNA vaccination protocols against cancer显示文摘	Chiarella P Fazio VM Signori E	2013	Curr Drug Metab2013，14，3：	1
10	Electroporation in DNA vacci- nation protocols against cancer 显示文摘	Chiarella P Fazio VM Signori E	2013	Curt Drug Metab2013，14，3：	1
11	Sperm cells asvectors for introducing foreign DNA into eggs: genetic trans- formation of mice显示文摘	Lavitrano M Camaioni A Fazio VM	1989	Cell1989，57，5：	1
12	Sperm cells as vectors for introducing foreign DNA into eggs: genetic transformation of mice显示文摘	Lavitrano M Camaioni A Fazio VM	1989	Cell1989，59，2：	1
13	Design and pre-clini- cal development of epitope-based DNA vaccines against B-cell lymphoma 显示文摘	Iurescia S Fioretti D Fazio VM	2011	Curr Gene Ther2011，11，5：	1
14	Sperm cells as vectors for introducing foreign DNA into eggs:genetic transformation of mice显示文摘	Lavitrano M Camaioni A Fazio VM	1989	Cell1989，57，：	1
15	Sperm cells as vectors for introducing foreign DNA into eggs: genetic transformation of mice显示文摘	Lavitrano M Camaioni A Fazio VM	1989	Cell1989，57，：	1
16	DNA vaccines: developing new strategies against cancer 显示文摘	Fioretti D Iurescia S Fazio VM	2010	J Biomed Biotechnol2010，2010，17：	1
17	Sperm cells as vector for introducing foreign DNA into eggs:genetic transformation of mice显示文摘	Lavitrano M Camaioni A Fazio VM	1989	Cell1989，57，：	1
18	DNA vaccines: de- veloping new strategies against cancer 显示文摘	Fioretti D lurescia S Fazio VM at al	2010	J Biomed Biotechnol2010，2010，17：	1
19	Nucleotide Sperm cells as vectors for introducing foreign DNA into eggs: genetic transformation of mice显示文摘	Camaioni A Fazio VM	1989	Cell1989，57，5：	1
20	Sperm cells as vectors for introducing foreign DNA into eggs : genetic transformation of mice 显示文摘	cell lines Lavitrano M Camaioni A Fazio VM	1989	Cell1989，57，：	1

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