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| 1 | No association between cyclooxygenase-2 and uridine diphosphate glucuronosyltransferase 1A6 genetic polymorphisms and colon cancer risk显示文摘AIM:To investigate the association of variations in the cyclooxygenase-2(COX2) and uridine diphosphate glucuronosyltransferase 1A6(UGT1A6) genes and non-steroidal anti-inflammatory drugs(NSAIDs) use with risk of colon cancer.METHODS:NSAIDs,which are known to reduce the risk of colon cancer,act directly on COX2 and reduce its activity.Epidemiological studies have associated variations in the COX2 gene with colon cancer risk,but others were unable to replicate this finding.Similarly,enzymes in the UGT1A6 gene have been demonstrated to modify the therapeutic effect of NSAIDs on colon adenomas.Polymorphisms in the UGT1A6 gene have been statistically shown to interact with NSAID intake to influence risk of developing colon adenomas,but not colon cancer.Here we examined the association of tagging single nucleotide polymorphisms(SNPs) in the COX2 and UGT1A6 genes,and their interaction with NSAID consumption,on risk of colon cancer in a population of 422 colon cancer cases and 481 population controls.RESULTS:No SNP in either gene was individually statistically significantly associated with colon cancer,nor did they statistically significantly change the protective effect of NSAID consumption in our sample.Like others,we were unable to replicate the association of variants in the COX2 gene with colon cancer risk(P > 0.05),and we did not observe that these variants modify the protective effect of NSAIDs(P > 0.05).We were able to confirm the lack of association of variants in UGT1A6 with colon cancer risk,although further studies will have to be conducted to confirm the association of these variants with colon adenomas.CONCLUSION:Our study does not support a role of COX2 and UGT1A6 genetic variations in the development of colon cancer. | Cheryl L Thompson Sarah J Plummer Alona Merkulova Iona Cheng Thomas C Tucker Graham Casey Li Li | 2009 | World Journal of Gastroenterology2009，15，18： | 11 |
| 2 | 光伏电场对地表温度的影响研究显示文摘现有研究表明,光伏电场会对地表温度产生影响,但其影响范围和程度却尚未评价。该文基于多景Landsat数据,反演了电场建设前、后的地表温度,通过对比光伏电场建设前后地表温度的变化,探究光伏电场对地表温度的影响范围和程度,在此基础上利用MODIS的地表温度产品,评价研究区地表温度的昼夜和季节变化规律。结果表明光伏电场不仅改变了其占地范围内地表温度的自然变化规律,而且还影响到了周围100 m的缓冲区。与对照区相比,光伏电场在白天是明显的'冷岛',全年白天地表温度平均降幅为0.65℃;夜晚是明显的'热岛',全年夜晚地表温度平均升幅0.54℃。但夜晚的'热岛'和白天的'冷岛'效应在不同季节差异很大,夏天夜晚'热岛'效应最为明显,冬天白天'冷岛'效应最为明显。 | 李国庆 Armstrong Alona 刘哲 | 2020 | 太阳能学报2020，41，12： | 3 |
| 3 | No association between phosphatase and tensin homolog genetic polymorphisms and colon cancer显示文摘AIM: To investigate the association between single nucleotide polymorphisms (SNPs) in the phosphatase and tensin homolog (PTEN) tumor suppressor gene and risk of colon cancer. METHODS: We utilized a population-based casecontrol study of incident colon cancer individuals (n= 421) and controls (n = 483) aged ≥ 30 years to conduct a comprehensive tagSNP association analysis of the PTEN gene. RESULTS: None of the PTEN SNPs were statistically significantly associated with colon cancer when controlled for age, gender, and race, or when additionally adjusted for other known risk factors (P > 0.05). Haplotype analyses similarly showed no association between the PTEN gene and colon cancer. CONCLUSION: Our study does not support PTEN as a colon cancer susceptibility gene. | Lynette S Phillips Cheryl L Thompson Alona Merkulova Sarah J Plummer Thomas C Tucker Graham Case Li Li | 2009 | World Journal of Gastroenterology2009，15，30： | 2 |
| 4 | Mucin-Producing Neoplasms of the Pancreas: An Analysis of Distinguishing Clinical and Epidemiologic Characteristics显示文摘 | Stefano Crippa Carlos Fernández–del Castillo Roberto Salvia Dianne Finkelstein Claudio Bassi Ismael Domínguez Alona Muzikansky Sarah P. Thayer Massimo Falconi Mari Mino–Kenudson Paola Capelli Gregory Y. Lauwers Stefano Partelli Paolo Pederzoli Andrew L. W | 2010 | Clinical Gastroenterology and Hepatology2010，，2： | 2 |
| 5 | EMR for Barrett’s esophagus–related superficial neoplasms offers better diagnostic reproducibility than mucosal biopsy 显示文摘 | Mari Mino-Kenudson Mindy J. Hull Ian Brown Alona Muzikansky Amitabh Srivastava Jonathan Glickman Do-Youn Park Lawrence Zuckerberg Joseph Misdraji Robert D. Odze Gregory Y. Lauwers | 2007 | Gastrointestinal Endoscopy2007，，： | 2 |
| 6 | Relation between oxide thickness and the breakdown voltage of a planar junction with field relief electrode 显示文摘 | Patrick V O Alonas G P | 1979 | IEEE Trans Elec Dev1979，26，7： | 1 |
| 7 | Mechanical properties of natural fibers/polyamides composites 显示文摘 | ARCAYA P A ALONA R AITOR A | 2009 | Polym compos2009，30，3： | 1 |
| 8 | Design of electrically loaded wire antennas using genetic algorithm显示文摘 | Alona Boag Amir Boag Eric Michielssen Raj Mittra | 1996 | IEEE Transactions on Antennas and Propagation1996，44，5： | 1 |
| 9 | Downregulation of Microglial Activation by Achillolide A显示文摘 | Anat Elmann Alona Telerman Sharon Mordechay Hilla Erlank Miriam Rindner Yoel Kashman Rivka Ofir | 2015 | Planta Med2015，，： | 1 |
| 10 | Achieving hi10 resolution CW STED nanoscopy with a Ti: sapphire oscillator显示文摘 | Liu Y Ding Y Alonas E | 2012 | PIoS One2012，7，6： | 1 |
| 11 | Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors显示文摘 | Michael SF Jill RD Alona C | 1999 | Nature1999，401，6749： | 1 |
| 12 | Posttraomlatic symptoms,emolional distress and quality of life in long-tenn survivors of breast cancer A preliminary research显示文摘 | Marlalille A Alona R | 2002 | Anxity Disorders2002，16，： | 1 |
| 13 | Acyclic coloring ofgraphs显示文摘 | AlonA McDiarmidC ReedB | 1991 | Random Structures Algorithms1991，2，3： | 1 |
| 14 | Relation Between Oxide Thickness and the Breakdown Voltage of a Planar Junction with Field Relief Electrode显示文摘 | V PATRICK O'NEIL G ALONAS | 1979 | IEEE Transactions on Electron Devices1979，26，7： | 1 |
| 15 | Design of electrically loaded wire antennas using genetic algorithms显示文摘 | ALOnA BOAG AMIR BOAG | 1996 | IEEE Trans Antennas Propagat1996，44，5： | 1 |
| 16 | Posttraumatie symptoms, emotional distress and quality of life in long-term survivors of breast cancer: a preliminary research 显示文摘 | Marianne Amir Alona Ramati | 2002 | Anxiety Disorders2002，16，： | 1 |
| 17 | Design of Electrically Loaded Wire Antennas Using Genetic Algorithm 显示文摘 | Alona Boag Amir Boag Eric Michielssen et a l | 1996 | IEEE Transactions on Antennas and Propagation1996，44，5： | 1 |
| 18 | Dezignof Electrically Loaded Wire Antennas Using Genetic Algorithrns 显示文摘 | Alona Boag Amir Boag Erie Miehielessen Raj Mittra | 1996 | IEEE TRANSACTIONS ON ANTENNAS AND PROPAGATION1996，44，5： | 1 |
| 19 | Evidence for lipid peroxidation in obstructive sleep apnea显示文摘 | Lena Lavic Alona Vishncvsky Pereta Lavie | 2004 | Sleep2004，27，1： | 1 |
| 20 | Melamine detection in infant formula powder using nearand mid-infrared spectroscopy显示文摘 | Lisa J M Alona A Chernyshova A H | 2009 | J Agric Food Chem2009，57，10： | 1 |
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