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| 1 | Progress in carbon dioxide separation and capture: A review显示文摘这篇文章考察在 CO2 分离和俘获研究和工程取得的进步。各种各样的技术例如吸收,吸附,和膜分离,彻底地被讨论。象化学循环的燃烧和基于水合物的分离那样的新概念也简短被介绍。未来方向被建议。隐遁方法海洋授精和矿物质碳酸饱和技术例如造林,也被盖住。地下的注射和直接海洋垃圾场没被盖住。 | Hongqun Yang Zhenghe Xu Maohong Fan Rajender Gupta Rachid B Slimane Alan E Bland Ian Wright | 2008 | Journal of Environmental Sciences2008，20，1： | 89 |
| 2 | Systematic review of colorectal cancer screening guidelines for average-risk adults: Summarizing the current global recommendations显示文摘AIM To summarize and compare worldwide colorectal cancer(CRC) screening recommendations in order to identify similarities and disparities.METHODS A systematic literature search was performed using MEDLINE, EMBASE, Scopus, CENTRAL and ISI Web of knowledge identifying all average-risk CRC screening guideline publications within the last ten years and/or position statements published in the last 2 years. In addition, a hand-search of the webpages of National Gastroenterology Society websites, the National Guideline Clearinghouse, the BMJ Clinical Evidence website,Google and Google Scholar was performed. RESULTS Fifteen guidelines were identified. Six guidelines were published in North America, four in Europe, four in Asia and one from the World Gastroenterology Organization. The majority of guidelines recommend screening average-risk individuals between ages 50 and 75 using colonoscopy(every 10 years), or flexible sigmoidoscopy(FS, every 5 years) or fecal occult blood test(FOBT, mainly the Fecal Immunochemical Test, annually or biennially). Disparities throughout the different guidelines are found relating to the use of colonoscopy, rank order between test, screening intervals and optimal age ranges for screening. CONCLUSION Average risk individuals between 50 and 75 years should undergo CRC screening. Recommendations for optimal surveillance intervals, preferred tests/test cascade as well as the optimal timing when to start and stop screening differ regionally and should be considered for clinical decision making. Furthermore, local resource availability and patient preferences are important to increase CRC screening uptake, as any screening is better than none. | Florence Bénard Alan N Barkun Myriam Martel Daniel von Renteln | 2018 | World Journal of Gastroenterology2018，24，1： | 16 |
| 3 | Factors associated with time to laparoscopic cholecystectomy for acute cholecystitis显示文摘AIM: To determine patient and process of care factors associated with performance of timely laparoscopic cholecystectomy for acute cholecystitis. METHODS: A retrospective medical record review of 88 consecutive patients with acute cholecystitis was conducted. Data collected included demographic data, co-morbidities, symptoms and physical findings at presentation, laboratory and radiological investigations, length of stay, complications, and admission service (medical or surgical). Patients not undergoing cholecystectomy during this hospitalization were excluded from analysis. Hierarchical generalized linear models were constructed to assess the association of pre-operative diagnostic procedures, presenting signs, and admitting service with time to surgery.RESULTS: Seventy cases met inclusion and exclusion criteria, among which 12 were admitted to the medical service and 58 to the surgical service. Mean ± SD time to surgery was 39.3 ± 43 h, with 87% of operations performed within 72 h of hospital arrival. In the adjusted models, longer time to surgery was associated with number of diagnostic studies and endoscopic retrograde cholangio-pancreatography (ERCP, P = 0.01) as well with admission to medical service without adjustment for ERCP (P < 0.05). Patients undergoing both magnetic resonance cholangiopancreatography (MRCP) and computed tomography (CT) scans experienced the longest waits for surgery. Patients admitted to the surgical versus medical service underwent surgery earlier (30.4 ± 34.9 vs 82.7 ± 55.1 h, P < 0.01), had less post-operative complications (12% vs 58%, P < 0.01), and shorter length of stay (4.3 ± 3.4 vs 8.1 ± 5.2 d, P < 0.01).CONCLUSION: Admission to the medical service and performance of numerous diagnostic procedures, ERCP, or MRCP combined with CT scan were associated with longer time to surgery. Expeditious performance of ERCP and MRCP and admission of medically stable patients with suspected cholecystitis to the surgical service to speed up time to surgery should be considered. | Chris N Daniak David Peretz Jonathan M Fine Yun Wang Alan K Meinke William B Hale | 2008 | World Journal of Gastroenterology2008，14，7： | 13 |
| 4 | Osteoporosis in primary biliary cholangitis显示文摘Primary biliary cholangitis(PBC) is an autoimmune cholestatic liver disease with multiple debilitating complications. Osteoporosis is a common complication of PBC resulting in frequent fractures and leading to significant morbidity in this population, yet evidence for effective therapy is lacking. We sought to summarize our current understanding of the pathophysiology of osteoporosis in PBC, as well as current and emerging therapies in order to guide future research directions. A complete search with a comprehensive literature review was performed with studies from Pub Med, EMBASE, Web of Science, Cochrane database, and the Countway Library. Osteoporosis in PBC is driven primarily by decreased bone formation, which differs from the increased bone resorption seen in postmenopausal osteoporosis. Despite this fundamental difference, current treatment recommendations are based primarily on experience with postmenopausal osteoporosis. Trials specific to PBC-related osteoporosis are small and have not consistently demonstrated a benefit in this population. As it stands, prevention of osteoporosis in PBC relies on the mitigation of risk factors such as smoking and alcohol use, as well as encouraging a healthy diet and weight-bearing exercise. The primary medical intervention for the treatment of osteoporosis in PBC remains bisphosphonates though a benefit in terms of fracture reduction has never been shown. This review outlines what is known regarding the pathogenesis of bone disease in PBC and summarizes current and emerging therapies. | Christopher J Danford Hirsh D Trivedi Konstantinos Papamichael Elliot B Tapper Alan Bonder | 2018 | World Journal of Gastroenterology2018，24，31： | 13 |
| 5 | 关于GnRH拮抗剂最佳用法的文献综述显示文摘自1999年以来,促性腺激素释放激素(GnRH)拮抗剂开始在市场上销售。在体外受精或卵胞浆内单精子注射治疗过程中,GnRH拮抗剂可用于控制性卵巢刺激时预防黄体生成素(LH)早熟峰。越来越多的研究指出,GnRH拮抗剂安全有效,适用人群广泛。在这里,我们对近年来关于GnRH拮抗剂的应用研究进行了文献复习,并进一步对这种药物的最佳用法提出指南意见。涉及的人群包括:接受控制性卵巢刺激一线治疗的患者、低反应者以及多囊卵巢综合征妇女。GnRH拮抗剂治疗疗程短,注射频次少,不会对辅助生殖造成不良反应,因而是GnRH激动剂长方案治疗以外的又一有效手段。此外,使用GnRH拮抗剂可以减少促性腺激素的用量,因而患者依从性显著提高。 | Alan B Copperman Claudio Benadiva | 2016 | 生殖医学杂志2016，25，1： | 9 |
| 6 | Single nucleotide polymorphism in the tumor necrosis factor-alpha gene affects inflammatory bowel diseases risk显示文摘AIM: To investigate the role that single nucleotide polymorphisms (SNPs) in the promoter of the tumour necrosis factor-alpha (TNF-α) gene play in the risk of inflammatory bowel diseases (IBDs) in a New Zealand population, in the context of international studies. METHODS: DNA samples from 388 patients with Crohn's disease (CD), 405 ulcerative colitis (UC), 27 indeterminate colitis (IC) and 201 randomly selected controls, from Canterbury, New Zealand were screened for 3 common polymorphisms in the TNF-α receptor: -238 G→A, -308 G→A and -857C→T, using a TaqmanR assay. A meta-analysis was performed on the data obtained on these polymorphisms combined with that from other published studies. RESULTS: Individuals carrying the -308 G/A allele had a significantly (OR = 1.91, χ2 = 17.36, P < 0.0001) increased risk of pancolitis, and a 1.57-fold increased risk (OR = 1.57, χ2 = 4.34, P = 0.037) of requiring a bowel resection in UC. Carrying the -857 C/T variant decreased the risk of ileocolonic CD (OR = 0.56, χ2 =4.32, P = 0.037), and the need for a bowel resection (OR = 0.59, χ2 = 4.85, P = 0.028). The risk of UC was reduced in individuals who were smokers at diagnosis, (OR = 0.48, χ2 = 4.86, P = 0.028). CONCLUSION: TNF-α is a key cytokine known to play a role in inflammatory response, and the locus for the gene is found in the IBD3 region on chromosome 6p21, known to be associated with an increased risk for IBD. The -308 G/A SNP in the TNF-α promoter is functional, and may account in part for the increased UC risk associated with the IBD3 genomic region. The -857 C/T SNP may decrease IBD risk in certain groups. Pharmaco- or nutrigenomic approaches may be desir- able for individuals with such affected genotypes. | Lynnette R Ferguson Claudia Huebner Ivonne Petermann Richard B Gearry Murray L Barclay Pieter Demmers Alan McCulloch Dug Yeo Han | 2008 | World Journal of Gastroenterology2008，14，29： | 7 |
| 7 | Standard forward-viewing colonoscopy versus full-spectrum endoscopy: an international, multicentre, randomised, tandem colonoscopy trial显示文摘 | Ian M Gralnek Peter D Siersema Zamir Halpern Ori Segol Alaa Melhem Alain Suissa Erwin Santo Alan Sloyer Jay Fenster Leon M G Moons Vincent K Dik Ralph B D’Agostino Douglas K Rex | 2014 | Lancet Oncology2014，，3： | 6 |
| 8 | 电休克治疗对重度抑郁症患者脑功能网络的影响研究显示文摘电休克治疗(ECT)是一种能够对重度抑郁症(MDD)进行高效神经调节的干预技术,但其抗抑郁作用机制尚不明确。本文通过记录19例MDD患者在ECT前后的静息状态脑电(RS-EEG),从多角度分析了ECT对MDD患者静息态脑功能网络的调制作用:利用Welch算法估算自发脑电活动功率谱密度(PSD);基于虚部相干(iCoh)构建脑功能网络并计算功能连通性;利用最小生成树理论探究脑功能网络的拓扑结构特征。结果表明,MDD患者多个节律PSD、功能连通性和拓扑结构在ECT后发生了显著变化。本文研究结果揭示了ECT对MDD患者大脑活动的作用,对MDD的临床治疗和机制解析具有重要参考作用。 | 田树香 徐桂芝 杨新生 Paul B Fitzgerald Alan Wang | 2023 | 生物医学工程学杂志2023，40，3： | 3 |
| 9 | Implementation of a spatial decision support system for rural land use planning: integrating geographic information system and environmental models with search and optimisation algorithms显示文摘 | Keith B Matthews Alan R Sibbald Susan Craw | 1999 | Computers and Electronics in Agriculture1999，，1： | 2 |
| 10 | Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression显示文摘 | Yoo Byoung Kwon Emdad Luni Su Zao-zhong Villanueva Augusto Chiang Derek Y Mukhopadhyay Nitai D Mills Alan Scott Waxman Samuel Fisher Robert A Llovet Josep M Fisher Paul B Sarkar Devanand | 2009 | Journal of Clinical Investigation2009，，3： | 2 |
| 11 | WNT signaling in ovarian follicle biology and tumorigenesis显示文摘 | Alexandre B Alan K G Derek B | 2009 | Trends in Endocrinology and Metabolism2009，21，1： | 1 |
| 12 | Contiuous and bilevel positive airway pressure in the treatment of acute cardiogenic pulmonary edema 显示文摘 | Joshua M Kosowsky M D Alan B | 2000 | Am J Emerg Med2000，18，1： | 1 |
| 13 | A model of inherited wealth显示文摘 | Alan S B | 1975 | Quar- terly Journal of Economy1975，，3： | 1 |
| 14 | Orthographic projection capillary array fluo- rescent sensor for mHeahh显示文摘 | Joshua Balsam Hugh Alan Bruck b Avraham Rasooly | 2013 | Methods2013，，： | 1 |
| 15 | Interaction of trans-diamminedichloroplatinum (Ⅱ) with DNA: formation of monofunctional adducts and their reaction with glutathione显示文摘 | Alan E Michael A B | 1987 | Biochemistry1987，26，12： | 1 |
| 16 | Determining Lyapunov Exponents from a Time Series显示文摘 | Alan W Jack B S Harry L S | 1985 | Physica D1985，16，： | 1 |
| 17 | A lignan and pyrone and other constituents from Hyptis capitata 显示文摘 | Gunvor T A Alan C H Kurt B G T | 1991 | Phytochemistry1991，30，8： | 1 |
| 18 | 3D reconstruction of the carotid artery from two views using a single centerline显示文摘 | Kenneth R H Alan M W Peter B N | 2004 | International Congress Series2004，，： | 1 |
| 19 | Depression and risk of heart failure among older persons with isolated systolic hypertension显示文摘 | Jerome A Alan B Hadan MK | 2001 | Arch Intem Med2001，161，： | 1 |
| 20 | Towards a theory of quality nursing care for patients with cancer through hermeneutic phenomenology 显示文摘 | Andreas C Rena P Alan B | 2009 | European Journal of Oncology Nursing2009，13，： | 1 |
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