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| 1 | Magnetic resonance imaging in assessment of stress urinary incontinence in women: Parameters differentiating urethral hypermobility and intrinsic sphincter deficiency显示文摘AIM: To define the magnetic resonance imaging(MRI) parameters differentiating urethral hypermobility(UH) and intrinsic sphincter deficiency(ISD) in women with stress urinary incontinence(SUI).METHODS: The static and dynamic MR images of 21 patients with SUI were correlated to urodynamic(UD) findings and compared to those of 10 continent controls. For the assessment of the urethra and integrity of the urethral support structures, we applied the highresolution endocavitary MRI, such as intraurethral MRI, endovaginal or endorectal MRI. For the functional imaging of the urethral support, we performed dynamic MRI with the pelvic phased array coil. We assessed the following MRI parameters in both the patient and thevolunteer groups:(1) urethral angle;(2) bladder neck descent;(3) status of the periurethral ligaments,(4) vaginal shape;(5) urethral sphincter integrity, length and muscle thickness at mid urethra;(6) bladder neck funneling;(7) status of the puborectalis muscle;(8) pubo-vaginal distance. UDs parameters were assessed in the patient study group as follows:(1) urethral mobility angle on Q-tip test;(2) Valsalva leak point pressure(VLPP) measured at 250 cc bladder volume; and(3) maximum urethral closure pressure(MUCP). The UH type of SUI was defined with the Q-tip test angle over 30 degrees, and VLPP pressure over 60 cm H2 O. The ISD incontinence was defined with MUCP pressure below 20 cm H2 O, and VLPP pressure less or equal to 60 cm H2 O. We considered the associations between the MRI and clinical data and UDs using a variety of statistical tools to include linear regression, multivariate logistic regression and receiver operating characteristic(ROC) analysis. All statistical analyses were performed using STATA version 9.0(Stata Corp LP, College Station, TX).RESULTS: In the incontinent group, 52% have history of vaginal delivery trauma as compared to none in control group(P < 0.001). There was no difference between the continent volunteers and incontinent patients in body habitus as assessed by the body mass index. Pubovaginal distance and periurethral ligament disruption are significantly associated with incontinence; periurethral ligament symmetricity reduces the odds of incontinence by 87%. Bladder neck funneling and length of the suprapubic urethral sphincter are significantly associated with the type of incontinence on UDs; funneling reduced the odds of pure UH by almost 95%; increasing suprapubic urethral sphincter length at rest is highly associated with UH. Both MRI variables result in a predictive model for UDs diagnosis(area under the ROC = 0.944). CONCLUSION: MRI may play an important role in assessing the contribution of hypermobility and sphincteric dysfunction to the SUI in women when considering treatment options. | Katarzyna Jadwiga Macura Richard Eugene Thompson David Alan Bluemke Rene Genadry | 2015 | World Journal of Radiology2015，7，11： | 10 |
| 2 | Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study显示文摘 | Peter Connick Madhan Kolappan Charles Crawley Daniel J Webber Rickie Patani Andrew W Michell Ming-Qing Du Shi-Lu Luan Daniel R Altmann Alan J Thompson Alastair Compston Michael A Scott David H Miller Siddharthan Chandran | 2012 | Lancet Neurology2012，，2： | 2 |
| 3 | Short bowel syndrome and crohn’s disease显示文摘 | Jon S Thompson Kishore R Iyer John K DiBaise Renee L Young Cindy R Brown Alan N Langnas | 2003 | Journal of Gastrointestinal Surgery2003，，8： | 1 |
| 4 | Probabilistic estimate of rock mass static and dynamic demands for underground excavation stabilisation显示文摘Excavation damage under high in situ stress depends largely upon the potential block size associated with any violent ejection.The size and shape of the dynamic instability are largely controlled by the location,orientation and extent of the pre-existing geological discontinuities.A new methodology is presented in which the rock mass demand can be expressed in terms of the mass in tonnes of unstable rock that is ejected per unit area of the excavation surface where failure occurs.A probabilistic approach has been implemented to estimate the potential rock mass instabilities and their associated static and dynamic demands.The new methodology considers that the strain energy released by the rock mass during violent stress-driven failure is largely converted into kinetic energy of ejection for blocks.The estimated dynamic demand has been favourably compared with observations of rock mass damage in a number of underground excavations. | Ernesto Villaescusa Alan Thompson Christopher Windsor | 2019 | Journal of Rock Mechanics and Geotechnical Engineering2019，11，3： | 1 |
| 5 | The measurement of health related quality of life in patients with coronary heart disease显示文摘 | David R Thompson Alan Roebuck | 2001 | Journal of Cardiovascular Nursing2001，，16： | 1 |
| 6 | The scaling large sizes of CVD rotating disk reactors and comparison with theory 显示文摘 | Thompson Alan G Stall R A Zawadzki P | 1996 | Journal of Electronic Materials1996，25，： | 1 |
| 7 | A method for source apportion mentin biomass/coal blends using thermogravimetrie analysis 显示文摘 | Lester Edward Gong Mei Thompson Alan | 2007 | Journal of Analytieal and Applied Pyrolysis2007，80，1： | 1 |
| 8 | Clinical outcomes of single versus staged hybrid repair for thoracoabdominal aortic aneurysm显示文摘 | Ludovic Canaud Alan Karthikesalingam Dan Jackson Lynne Cresswell Michael Cliff S. Sheraz Markar Gary Maytham Steven Black Matt Thompson | 2013 | Journal of Vascular Surgery2013，，： | 1 |
| 9 | Guidelines for physicians with patients on IFN beta -1β:the use of an assay for neutralizing antibodies显示文摘 | Paty Donald W Goodkin Donald Thompson Alan | 1996 | Neurology1996，47，： | 1 |
| 10 | Clinically isolated syndromes suggestive of multiple sclerosis, part I: natural history, pathogenesis, diagnosis, and prognosis显示文摘 | David Miller Frederik Barkhof Xavier Montalban Alan Thompson Massimo Filippi | 2005 | Lancet Neurology2005，，5： | 1 |
| 11 | Diffusion-based tractography in neurological disorders: concepts, applications, and future developments显示文摘 | Olga Ciccarelli Marco Catani Heidi Johansen-Berg Chris Clark Alan Thompson | 2008 | Lancet Neurology2008，，8： | 1 |
| 12 | Effectiveness of Prehospital Wireless Transmission of Electrocardiograms to a Cardiologist Via Hand-Held Device for Patients With Acute Myocardial Infarction (from the Timely Intervention in Myocardial Emergency, NorthEast Experience [TIME-NE])显示文摘 | George L. Adams Paul T. Campbell John M. Adams David G. Strauss Karen Wall Janet Patterson Kathy B. Shuping Charles Maynard Dwayne Young Craig Corey Alan Thompson Benjamin A. Lee Galen S. Wagner | 2006 | The American Journal of Cardiology2006，，9： | 1 |
| 13 | Prehospital triage of acute myocardial infarction: wireless transmission of electrocardiograms to the on-call cardiologist via a handheld computer显示文摘 | Paul T. Campbell Janet Patterson Deedee Cromer Karen Wall George L. Adams Alfred Albano Craig Corey Paula Fox Jim Gardner Barry Hawthorne Jonathan Lipton Maria Sejersten Alan Thompson Amanda Thompson Susan Wilfong Charles Maynard Galen Wagner | 2005 | Journal of Electrocardiology2005，，4： | 1 |
| 14 | 改进型SOA电路实现安全工作区保护显示文摘功率管保护是通过将其操作限制在SOA的有限V-I平面(plane)区域内,保护电路通常采用返送(foldback)电流限制,但这种方法无法复制SOA功率界限的实际形状。本文将以TI的TPS2490系列功率限制(power-limiting)热插拔控制器为例介绍改进型SOA保护电路的原理与设计,它可通过模拟计算技术复制SOA的实际界限。 | Alan Hastings Lemuel Thompson Fred Trafton | 2004 | 电子测试(新电子)2004，，12： | 1 |
| 15 | Water level fluctuation and sediment–water nutrient exchange in Great Lakes coastal wetlands显示文摘 | Alan D. Steinman Mary E. Ogdahl Maggie Weinert Kurt Thompson Matthew J. Cooper Donald G. Uzarski | 2012 | Journal of Great Lakes Research2012，，4： | 1 |
| 16 | Moving target performance for RADARSAT-2 显示文摘 | Alan A Thompson Charles E Livingstone | 2000 | IEEE Trans2000，38，6： | 1 |
| 17 | A Systematic Review of Aortic Remodeling After Endovascular Repair of Type B Aortic Dissection: Methods and Outcomes显示文摘 | Benjamin O. Patterson Richard J. Cobb Alan Karthikesalingam Peter J. Holt Robert J. Hinchliffe Ian M. Loftus Matt M. Thompson | 2013 | The Annals of Thoracic Surgery2013，，： | 1 |
| 18 | Moving Target Performance for RADARSAT-2显示文摘 | Alan A Thompson Charles E Livingstone | 2000 | IEEE Trans2000，38，6： | 1 |
| 19 | Fluid-absent (dehydration) melting of biotite in metapelites in the early stages of crustal anatexis显示文摘 | Nicole Le Breton Alan Bruce Thompson | 1988 | Contributions to Mineralogy and Petrology1988，，2： | 1 |
| 20 | Metabolic engineering of Aspergillus oryzae NRRL 3488 for increased production of l -malic acid显示文摘 | Stephen H. Brown Lena Bashkirova Randy Berka Tyler Chandler Tammy Doty Keith McCall Michael McCulloch Sarah McFarland Sheryl Thompson Debbie Yaver Alan Berry | 2013 | Applied Microbiology and Biotechnology2013，，20： | 1 |
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