|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 长江口潮滩有机质来源的C、N稳定同位素示踪显示文摘依据长江河口潮滩自然环境特征和受人文活动影响的差异性,沿长江河口南岸潮滩选取了12个典型的监测站位,并分别于洪水季节(7月份)和枯水季节(2月份)在各监测站位进行了表层(0~2cm)沉积物样品的采集。对表层沉积物有机质中稳定碳、氮同位素进行分析与测试发现,7月份稳定碳同位素值普遍低于2月份的稳定碳同位素值,其变化范围分别为-29.8‰^-23.7‰和-27.3‰^-25.6‰;7月份和2月份稳定氮同位素分别为1.0‰~5.5‰和1.7‰~7.8‰。研究区域内,稳定碳、氮同位素的地区分布和季节变化特征揭示,有机质中的稳定碳、氮同位素组成不仅受陆源和海源有机质输入量之间消长变化的影响,同时一系列的生物地球化学过程、人为有机质的输入和沉积物粒度与叶绿素对碳、氮同位素组成均存在不同程度的改造作用。此外,利用稳定碳同位素质量平衡混合模型。 | 刘敏 侯立军 许世远 欧冬妮 蒋海燕 余婕 Gardner WayneS | 2004 | 地理学报2004，59，6： | 46 |
| 2 | 护士在从事卫生宣教、治疗和预防职业性HIV传播中应起的作用显示文摘人们越来越认识到 AIDS 和护理的关系。护士不仅在治疗和预防 AIDS 中作出贡献,作为病人的权利维护者,咨询者,还应在公众教育中担负更主动的工作。在从事关于 AIDS 防治的工作中,护士除了要有献身精神外,还应学会保护自己的种种方法。 | Gardner C 徐远鲲 | 1992 | 国外医学(护理学分册)1992，11，3： | 33 |
| 3 | What is artificial meat and what does it mean for the future of the meat industry?显示文摘The meat industry cannot respond to increases in demand by ever increasing resource use. The industry must find solutions to issues regarding animal welfare, health and sustainability and will have to do so in the face of competition from emerging non-traditional meat and protein products in an increasingly complex regulatory environment. These novel meat and protein products, otherwise known as ‘artificial meat' are utilising ground breaking technologies designed to meet the issues facing the conventional meat industry. These artificial meats, in vitro or cultured meat and meat from genetically modified organisms have no real capacity to compete with conventional meat production in the present environment. However, meat replacements manufactured from plant proteins and mycoproteins are currently the biggest competitors and are gaining a small percentage of the market. Manufactured meats may push conventional meat into the premium end of the market, and supply the bulk, cheap end of the market if conventional meat products become more expensive and the palatability and versatility of manufactured meats improve. In time the technology for other artificial meats such as meat from genetic modified organisms or cultured meat may become sufficiently developed for these products to enter the market with no complexity of the competition between meat products. Conventional meat producers can assimilate agroecology ecology concepts in order to develop sustainable animal production systems. The conventional meat industry can also benefit from assimilating biotechnologies such as cloning and genetic modification technologies, using the technology to adapt to the changing environment and respond to the increasing competition from artificial meats. Although it will depend at least partly on the evolution of conventional meat production, the future of artificial meat produced from stem cells appears uncertain at this time. | Sarah P F Bonny Graham E Gardner David W Pethick Jean-Franois Hocquette | 2015 | Journal of Integrative Agriculture2015，14，2： | 15 |
| 4 | 内镜经翼突入路的解剖及其在处理颅底病变中的应用显示文摘目的通过内镜经鼻经翼突入路解剖研究获得相关解剖标志,总结应用该径路处理蝶骨翼突周围颅底病变的经验。方法2例(4侧)成人尸头经血管硅胶灌注后,行导航CT扫描后进行手术入路解剖,拍摄获得高清图像。回顾性分析内镜经鼻经翼突入路治疗的12例颅底病变患者的临床资料。其中蝶窦侧隐窝自发性脑脊液鼻漏3例;翼腭窝、颞下窝神经鞘瘤2例,神经纤维瘤2例;中颅窝颞下窝沟通皮样囊肿1例、颅底侵袭性真菌病1例、上咽旁间隙基底细胞腺瘤1例;腺样囊性癌1例、颅底软骨肉瘤1例。结果在人路解剖方面,获得该入路的一些重要解剖标志,如蝶腭孔及其内容物、翼管及其内容物、三叉神经上颌支及圆孔、三叉神经下颌支和卵圆孔、咽鼓管翼突部等。3例自发性脑脊液鼻漏患者一次性修补成功;4例翼腭窝、颞下窝神经来源的良性肿瘤患者术中全切,术后随访10~120个月无复发。颅底皮样囊肿、颅底侵袭性真菌病、上咽旁间隙基底细胞腺瘤患者,病变全切,随访13~84个月无复发。颅底软骨肉瘤患者术中肿瘤大部分切除,术后放化疗,肿瘤控制;腺样囊性癌患者,术中肿瘤全切,术后随访5年复发,再次手术。除2例术后短期出现腭部麻木感觉异常外,无其他并发症。结论掌握翼突入路的解剖标志对于处理翼突周围的颅底病变有重要意义。内镜经鼻经翼突入路是处理部分翼突周围颅底病变的安全有效的技术。 | 刘剑锋 韩军 杨大章 刘丹丹 李锐 于炎冰 张秋航 Juan C. Fernandez-Miranda Paul A. Gardner Carl H. Snyderman | 2015 | 中华耳鼻咽喉头颈外科杂志2015，50，11： | 10 |
| 5 | Atkins、Zone、Ornish和LEARN饮食对绝经后超重妇女体重及相关危险因素变化的影响——A TO Z减肥研究:随机试验显示文摘背景:时下盛行的饮食(尤其是低碳水化合物饮食)与当前推荐的低脂、高碳水化合物减肥饮食有所抵触。迄今为止,人们尚未充分研究不同饮食的潜在利弊。
目的:比较4种减肥饮食(代表着各种碳水化合物摄入量)对减肥及相关代谢指标的影响。
设计、地点及参试者:2003年2月至2005年10月在美国311名绝经后超重、肥胖(体重指数为27—40)妇女中开展为期12个月的随机试验,这些妇女生活自在,无糖尿病。 | Christopher D. Gardner Alexandre Kiazand Sofiya Alhassan 顾佳(译) | 2007 | 美国医学会杂志(中文版)2007，26，4： | 10 |
| 6 | 不锈钢焊接箱形截面柱轴心受压相关稳定试验研究显示文摘不锈钢的非线性材料特性使其构件承载性能不同于普通钢结构构件,需要开展专门的研究。通过焊接加工8个不锈钢箱形截面柱,包括奥氏体型S30408和双相型S22253两种牌号,在试件两端铰接的约束条件下开展轴心承压加载试验。试验中对板材力学性能、试件的局部与整体几何初始缺陷、纵向焊接残余应力分布和加载初偏心进行了测量。加载试验得出了板件的局部屈曲承载力与构件的相关稳定承载力,展示了从组成板件局部屈曲到构件整体弯曲屈曲的渐变失效形态。将试验结果与欧洲不锈钢规范EN 1993-1-4、直接强度法和中国冷弯薄壁型钢结构技术规范GB 50018的计算公式进行比较表明,由于欧洲规范和直接强度法没有考虑不同牌号不锈钢材料力学性能的差异,对双相型S22253构件的承载力计算偏于保守,而奥氏体型S30408构件的计算承载力偏于不安全;而中国规范GB 50018没有考虑焊接残余应力、几何缺陷和材料非线性的不利影响,高估了构件的相关稳定承载力。所得到的试验结果将为后续的数值分析与理论研究提供数据支撑。 | 袁焕鑫 王元清 石永久 李铮 Gardner L. | 2015 | 土木工程学报2015，48，2： | 9 |
| 7 | Oxidative stress and extracellular matrices after hepatectomy and liver transplantation in rats显示文摘AIM:To investigate oxidative stress(OS)-mediated damage and the behavior of extracellular matrices in various rat models because shear stress with portal hypertension and cold ischemia/warm reperfusion injury trigger the liver regeneration cascade after surgery. These injuries also cause fatal liver damage.METHODS: Rats were divided into four groups according to the surgery performed: control; hepatectomy with 40% liver remnant(60% hepatectomy); orthotopic liver transplantation(OLT) with whole liver graft(100% OLT); and split OLT(SOLT) with 40% graft(40% SOLT). Survival was evaluated. Blood and liver samples were collected at 6 h after surgery. Biochemical and histopathological examinations were performed. OSinduced damage, 4-hydroxynonenal, ataxia-telangiectasia mutated kinase, histone H2AX, phosphatidylinositol 3-kinase(PI3K) and Akt were evaluated by western blotting. Behavior of extracellular matrices, matrix metalloproteinase(MMP)-9, MMP-2, tissue inhibitor of metalloproteinase(TIMP)-1 and TIMP-2 were also evaluated by western blotting and zymography. RESULTS: Although 100% OLT survived, 60% hepatectomy and 40% SOLT showed poor survival. Histopathological, immunohistological, biochemical and protein assays revealed that 60% hepatectomy, 100% OLT and 40% SOLT showed liver damage. PI3K and Akt were decreased in 60% hepatectomy and 40% SOLT. For protein expression, 40% SOLT showed differences in MMP-9, MMP-2 and TIMP-2. TIMP-1 showed differences in 60% hepatectomy and 40% SOLT. For protein activity, MMP-9 demonstrated significant differences in 60% hepatectomy, 100% OLT and 40% SOLT. CONCLUSION: Under conditions with an insufficient liver remnant, prevention of OS-induced damage via the Akt/PI3K pathway may be key to improve the postoperative course. MMP-9 may be also a therapeutic target after surgery. | Tomohide Hori Shinji Uemoto Feng Chen Lindsay B Gardner Ann-Marie T Baine Toshiyuki Hata Takayuki Kogure Justin H Nguyen | 2014 | World Journal of Hepatology2014，6，2： | 7 |
| 8 | Evaluation of combination gene therapy with PTEN and antisense hTERT for malignant glioma in vitro and xenografts显示文摘 | You, Y. P. Geng, X. Z. Zhao, P. FU, Z. Wang, C. Z. Chao, S. W. Liu, N. Lu, A. L. Gardner, K. Pu, P. Y. Kong, C. S. Ge, Y. Judge, S. I. V. Li, Q. D. Q | 2007 | 南京医科大学学报(自然科学版)2007，27，5： | 6 |
| 9 | 澳大利亚水资源分配与管理原则及其对我国的启示显示文摘今天世界上许多国家都面临水资源短缺的问题,怎样对现有的水资源进行分配,如何对水资源进行有效的管理显得尤为重要。澳大利亚政府在这方面进行了卓有成效的尝试。基于此,首先介绍了澳大利亚水资源的现状,其次分析了澳大利亚水资源分配和管理的原则,最后阐述了澳大利亚在水资源分配和管理方面对我国的启示。 | 张艳芳 Alex Gardner | 2009 | 科技进步与对策2009，26，23： | 6 |
| 10 | Drug eluting biliary stents to decrease stent failure rates:Areview of the literature显示文摘Biliary stenting is clinically effective in relieving both malignant and non-malignant obstructions. However, there are high failure rates associated with tumor ingrowth and epithelial overgrowth as well as internally from biofilm development and subsequent clogging. Within the last decade, the use of prophylactic drug eluting stents as a means to reduce stent failure has been investigated. In this review we provide an overview of the current research on drug eluting biliary stents. While there is limited human trial data regarding the clinical benefit of drug eluting biliary stents in preventing stent obstruction, recent research suggests promise regarding their safety and potential efficacy. | Joseph Shatzel Jisoo Kim Kartik Sampath Sharjeel Syed Jennifer Saad Zilla H Hussain Kabir Mody J Marc Pipas Stuart Gordon Timothy Gardner Richard I Rothstein | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，2： | 6 |
| 11 | 焊接箱形截面不锈钢柱相关稳定性能分析显示文摘采用有限元法对焊接箱形截面不锈钢柱的局部与整体相关稳定性能进行分析,研究利用板件的屈曲后强度,以实现更为经济合理的构件截面设计。建立了可以准确模拟不锈钢非线性材料力学性能、截面焊接残余应力和构件的局部与整体几何初始缺陷等因素的精确有限元数值模型,并依据试验结果对模型的可靠性进行了验证。基于验证可靠的有限元模型,开展了系统参数分析,同时补充了大量的数值计算数据点。根据得到的试验和有限计算结果,对相关稳定承载力的理论计算方法进行了比较分析,表明现有的方法应用较为复杂,而且可能高估构件的相关稳定承载力。针对奥氏体型和双相型两类不锈钢提出了通用的计算修正系数,给出了新的直接强度法计算公式,经试验与有限元计算结果验证,表明其能够准确计算焊接箱形截面不锈钢柱的相关稳定承载力。 | 袁焕鑫 王元清 石永久 朱一锋 Gardner Leroy | 2015 | 工程力学2015，32，9： | 6 |
| 12 | A student’s contributions to second-language learning. Part II: Affective variables显示文摘 | R. C. Gardner P. D. MacIntyre | 1993 | Language Teaching1993，，1： | 4 |
| 13 | SOME STEADY-STATE SOLUTIONS OF THE UNSATURATED MOISTURE FLOW EQUATION WITH APPLICATION TO EVAPORATION FROM A WATER TABLE显示文摘 | W. R. GARDNER | 1958 | Soil Science1958，，4： | 4 |
| 14 | 英国“新机会基金”培训的分析及对我国教师教育技术能力培训的启示(三)显示文摘 | 袁莉 John Gardner(约翰·加德纳) Pamela Cowan(帕米拉·柯文) | 2005 | 教育信息化2005，，12X： | 4 |
| 15 | Simple and reproducible hepatectomy in the mouse using the clip technique显示文摘AIM: To investigate the reliability of massive hepatectomy models by using clip techniques. METHODS: We analyzed anatomical findings in 100 mice following massive hepatectomy induced by liver reduction > 70%. The impact of various factors in the different models was also analyzed, including learning curves, operative time, survival curves, and histopathological findings.RESULTS: According to anatomical results, models with 75%, 80%, and 90% hepatectomy produced massive hepatectomy. Learning curves and operative times were most optimal with the clip technique. Each hepatectomy performed using the clip technique produced a reasonable survival curve, and there were no differences in histopathological findings between the suture and clip techniques. CONCLUSION: Massive hepatectomy by the clip technique is simple and can provide reliable and relevant data. | Tomohide Hori Norifumi Ohashi Feng Chen Ann-Marie T Baine Lindsay B Gardner Toshiyuki Hata Shinji Uemoto Justin H Nguyen | 2012 | World Journal of Gastroenterology2012，18，22： | 4 |
| 16 | A prospective randomized trial of blastocyst culture and transfer in in-vitro fertilization显示文摘 | Gardner D K Schoolcraft W B Wagley L | 1998 | Hum Reprod1998，13，12： | 3 |
| 17 | Tumor shrinkage by cyclopamine tartrate through inhibiting hedgehog signaling显示文摘The link of hedgehog (Hh) signaling activation to human cancer and synthesis of a variety of Hh signaling inhibitors raise great expectation that inhibiting Hh signaling may be effective in human cancer treatment. Cyclopamine (Cyc), an alkaloid from the Veratrum plant, is a specific natural product inhibitor of the Hh pathway that acts by targeting smoothened (SMO) protein. However, its poor solubility, acid sensitivity, and weak potency relative to other Hh antagonists prevent the clinical development of Cyc as a therapeutic agent. Here, we report properties of cyclopamine tartrate salt (CycT) and its activities in Hh signaling-mediated cancer in vitro and in vivo. Unlike Cyc, CycT is water soluble (5-10 mg/mL). The median lethal dose (LD50) of CycT was 62.5 mg/kg body weight compared to 43.5 mg/kg for Cyc, and the plasma half-life (T1/2) of CycT was not significantly different from that of Cyc. We showed that CycT had a higher inhibitory activity for Hh signaling-dependent motor neuron differentiation than did Cyc (IC50 = 50 nmol/L for CycT vs. 300 nmol/L for Cyc). We also tested the antitumor effectiveness of these Hh inhibitors using two mouse models of basal cell carcinomas (K14cre:Ptch1neo/neo and K14cre:SmoM2YFP). After topical application of CycT or Cyc daily for 21 days, we found that all CycT-treated mice had tumor shrinkage and decreased expression of Hh target genes. Taken together, we found that CycT is an effective inhibitor of Hh signaling-mediated carcinogenesis. | Qipeng Fan Dongsheng Gu Miao He Hailan Liu Tao Sheng Guorui Xie Ching-xin Li Xiaoli Zhang Brandon Wainwright Arash Garrossian Massoud Garrossian Dale Gardner Jingwu Xie | 2011 | Chinese Journal of Cancer2011，30，7： | 3 |
| 18 | Long-term safety of lamivudine treatment in patients with chronic hepatitis B显示文摘 | Anna S.F Lok Ching-Lung Lai Nancy Leung Guang-Bi Yao Zhen-Yu Cui Eugene R Schiff Jules L Dienstag E.Jenny Heathcote Nancy R Little Dorothea A Griffiths Stephen D Gardner Mary Castiglia | 2003 | Gastroenterology2003，，6： | 3 |
| 19 | 图书馆罚款规定是否早该废除了显示文摘伊里娜·弗赖曼经常光顾波士顿西郊的几个图书馆。但她最钟情的还是红砖墙的多佛镇图书馆,部分原因是它所提供的独特优惠:过期归还资料不交罚款。星期六下午,弗赖曼女士及其家人前往借书处的路上时说:'这并不是钱的问题,问题是如果我把钱包忘在车里,交罚款就很不方便。而且这里的人更友好。'方便和友好就是多佛图书管理员们7年前取消罚款时意图达到的两个目标。 | Marilyn Gardner 冷迪 | 2006 | 英语文摘2006，，7： | 3 |
| 20 | Patterns of genomic and phenomic diversity in wine and table grapes显示文摘Grapes are one of the most economically and culturally important crops worldwide,and they have been bred for both winemaking and fresh consumption.Here we evaluate patterns of diversity across 33 phenotypes collected over a 17-year period from 580 table and wine grape accessions that belong to one of the world’s largest grape gene banks,the grape germplasm collection of the United States Department of Agriculture.We find that phenological events throughout the growing season are correlated,and quantify the marked difference in size between table and wine grapes.By pairing publicly available historical phenotype data with genome-wide polymorphism data,we identify large effect loci controlling traits that have been targeted during domestication and breeding,including hermaphroditism,lighter skin pigmentation and muscat aroma.Breeding for larger berries in table grapes was traditionally concentrated in geographic regions where Islam predominates and alcohol was prohibited,whereas wine grapes retained the ancestral smaller size that is more desirable for winemaking in predominantly Christian regions.We uncover a novel locus with a suggestive association with berry size that harbors a signature of positive selection for larger berries.Our results suggest that religious rules concerning alcohol consumption have had a marked impact on patterns of phenomic and genomic diversity in grapes. | ZoëMigicovsky Jason Sawler Kyle M Gardner Mallikarjuna K Aradhya Bernard H Prins Heidi R Schwaninger Carlos D Bustamante Edward S Buckler Gan-Yuan Zhong Patrick J Brown Sean Myles | 2017 | Horticulture Research2017，4，1： | 3 |
您所在的机构暂未开通此部分的功能，请联系管理员