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323篇 您的检索式:作者名="ALEXIOU C"
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1Ketamine anesthesia reduces intestinal ischemia/reperfusion injury in rats显示文摘AIM: To investigate the effects of ketamine anesthesia on the motility alterations and tissue injury caused by ischemia/reperfusion in rats. METHODS: Thirty male Wistar rats weighing 200-250 g were used. Ischemia was induced by ob-structing blood flow in 25% of the total small intesti-nal length (ileum) with a vascular clamp for 45 min, after which either 60 min or 24 h of reperfusion was allowed. Rats were either anesthetized with pento-barbital sodium (50 mg/kg) or ketamine (100 mg/kg). Control groups received sham surgery. After 60 min of reperfusion, the intestine was examined for mor-phological alterations, and after 24 h intestinal basic electrical rhythm (BER) frequency was calculated, and intestinal transit determined in all groups. RESULTS: The intestinal mucosa in rats that were anesthetized with ketamine showed moderate altera-tions such as epithelial lifting, while ulceration and hemorrhage was observed in rats that received pento-barbital sodium after 60 min of reperfusion. Quantita-tive analysis of structural damage using the Chiu scaleshowed significantly less injury in rats that received ketamine than in rats that did not (2.35 ± 1.14 vs 4.58 ± 0.50, P < 0.0001). The distance traveled by a mark-er, expressed as percentage of total intestinal length, in rats that received pentobarbital sodium was 20% ± 2% in comparison with 25.9% ± 1.64% in rats that re-ceived ketamine (P = 0.017). BER was not statistically different between groups. CONCLUSION: Our results show that ketamine anesthesia is associated with diminished intestinal injury and abolishes the intestinal transit delay induced by ischemia/reperfusion.Carlos Rodrigo Cámara Francisco Javier Guzmán Ernesto Alexis Barrera Andrés Jesús Cabello Armando Garcia Nancy Esthela Fernández Eloy Caballero Jesus Ancer 2008World Journal of Gastroenterology2008,14,33:5
2Towards high-throughput identification of endocrine disrupting compounds with mass spectrometry显示文摘Cédric Bovet Benoit Plet Marc Ruff Sylvia Eiler Florence Granger Andreas Panagiotidis Ryan Wenzel Alexis Nazabal Dino Moras Renato Zenobi 2009Toxicology in Vitro2009,,4:2
3Exatramed- ullary palsmacytoma: Tumor occurrence and therapeutic concepts 显示文摘Alexiou C Kau R J Dietzfelbinger H 1999Cancer1999,85,11:1
4Locoregional cancer treatment with magnetic drug targeting 显示文摘ALEXIOU C ARNOLD W KLEIN R J 2000Cancer Res2000,60,23:1
5Repair of tetralogy of Fallot in infancy with a transventricular or a transatrial approach 显示文摘Alexiou C Chen Q Galogavrou M 2002Eur J Cardio Thorac Surg2002,22,2:1
6Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons显示文摘Alexis M S Thiruma V A Roy G C 2008Nat Neurosci2008,11,:1
7A new complex homozygous large rearrangement of the PINK1 gene in a Sudanese family with early onset Parkinson’s disease显示文摘Cécile Cazeneuve Channkanira San Salah A. Ibrahim Maowia M. Mukhtar Musa M. Kheir Eric LeGuern Alexis Brice Mustafa A. Salih 2009neurogenetics2009,,3:1
8Black carbon contribution to soil organic matter composition in tropical sloping land under slash and burn agricul- ture显示文摘Rumpel C Alexis M Chabbi A 2006Geoderma2006,130,12:1
9Superconducting Materials for Large Scale Applications显示文摘Ronald M Alexis P David C 2004Appl Supercond2004,92,10:1
10Clinical appli cation of magnetic drug targeting显示文摘Lubbe A S Alexiou C Bergemann C 2001Journal of Surgical Research2001,95,2:1
11Do women live longer following lung resection for carcinoma 显示文摘Alexiou C Onyeaka CV Beggs D 2002Eur J Cardliothorae Surg2002,21,:1
12Chronic stress induces upregulation of brain-derived neurotrophic factor (BDNF) mRNA and integrin α- expression in the rat pineal gland 显示文摘ALEXIES DS RODRIGO Z C GABRIELA D V 2006Brian Res2006,1086,:1
13Targeting cancer cells: Magnetic nanoparticles as drug carriers显示文摘Alexiou C Schmid R 2006European Biophysics Journal With Biophysics Letters2006,35,5:1
14The inflammatory response to cardiopulmonary bypass:part 1-mechanisms of pathogenesis 显示文摘Warren O J Smith A J Alexiou C 2009Cardiothorac Vase Anesth2009,23,2:1
15Black carbon contribution to soil organic matter composition in tropical sloping land under slash and burn agriculture显示文摘Rumpel C Alexis M Chabbi A 2006Geoderma2006,130,:1
16Extramedullary plasmacytoma: tumor occurrence and therapeutic concepts 显示文摘Alexiou C Kau RJ Dietzfelbinger H 1999Cancer1999,85,11:1
17Locoregional cancer treatment with magnetic drug targeting 显示文摘Alexiou C Arnold W Klein RJ 2000Cancer Research2000,60,23:1
18Extramedullary plasmacytoma: tumor occurrence and therapeutic concepts 显示文摘Alexiou C Kan R J Dietzfelbinger H 1999Cancer1999,85,11:1
19Magnetic drug targeting: Biodistribution and dependency on magnetic field strength显示文摘Alexiou C Schmidt A Hulin P 2002Journal of Magnetism and Magnetic Materials2002,252,13:1
20Extramedullary plasmacytoma:tumor occurrence and therapeutic concepts显示文摘Alexiou C Kau RJ Pietzfelbinger H 1999Cancer1999,85,11:1
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