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| 1 | Biomaterial-based strategies for maxillofacial tumour therapy and bone defect regeneration显示文摘Issues caused by maxillofacial tumours involve not only dealing with tumours but also repairing jaw bone defects.In traditional tumour therapy,the systemic toxicity of chemotherapeutic drugs,invasive surgical resection,intractable tumour recurrence,and metastasis are major threats to the patients’lives in the clinic.Fortunately,biomaterial-based intervention can improve the efficiency of tumour treatment and decrease the possibility of recurrence and metastasis,suggesting new promising antitumour therapies.In addition,maxillofacial bone tissue defects caused by tumours and their treatment can negatively affect the physiological and psychological health of patients,and investment in treatment can result in a multitude of burdens to society.Biomaterials are promising options because they have good biocompatibility and bioactive properties for stimulation of bone regeneration.More interestingly,an integrated material regimen that combines tumour therapy with bone repair is a promising treatment option.Herein,we summarized traditional and biomaterial-mediated maxillofacial tumour treatments and analysed biomaterials for bone defect repair.Furthermore,we proposed a promising and superior design of dual-functional biomaterials for simultaneous tumour therapy and bone regeneration to provide a new strategy for managing maxillofacial tumours and improve the quality of life of patients in the future. | Bowen Tan Quan Tang Yongjin Zhong Yali Wei Linfeng He Yanting Wu Jiabao Wu Jinfeng Liao | 2021 | International Journal of Oral Science2021,13,1: | 9 |
| 2 | The mitochondrial genome encodes abundant small noncoding RNAs显示文摘识别的小 noncoding RNA 都被原子染色体远因此编码。这里,我们主要报导鼠科、人的 mitochondrial 染色体编码几千小 noncoding RNA,它是源于 mitochondrial 基因(主人基因) 的感觉抄本,并且我们称为这些小 RNA mitochondrial 编码染色体的小 RNA (mitosRNAs ) 。影响的 DICER inactivation,但是完全没废除 mitosRNA 生产。MitosRNAs 看起来是当前未辩别出的 mitochondrial ribonucleases 的产品。提高的表示在 vitro 他们的主人基因铺平的 mitosRNAs 的 Overexpression,和 dysregulated mitosRNA 表示通常在 vivo 与异常 mitochondrial 基因表示被联系。我们的数据证明除了 37 已知的 mitochondrial 基因,哺乳动物的 mitochondrial 染色体也编码丰富的 mitosRNAs,它可以在房间在 mitochondrial 基因表示的控制起一个重要规章的作用。 | Seungil Ro Hsiu-Yen Ma Chanjae Park Nicole Ortogero Rui Song Grant W Hennig Huili Zheng Yung-Ming Lin2 Loredana Moro Jer-Tsong Hsieh wei Yant | 2013 | Cell Research2013,23,6: | 3 |
| 3 | Optimal Reinsurance Under Distortion Risk Measures and Expected Value Premium Principle for Reinsurer显示文摘This paper discusses optimal reinsurance strategy by minimizing insurer's risk under one general risk measure:Distortion risk measure.The authors assume that the reinsurance premium is determined by the expected value premium principle and the retained loss of the insurer is an increasing function of the initial loss.An explicit solution of the insurer's optimal reinsurance problem is obtained.The optimal strategies for some special distortion risk measures,such as value-at-risk(VaR) and tail value-at-risk(TVaR),are also investigated. | ZHENG Yanting CUI Wei YANG Jingping | 2015 | Journal of Systems Science & Complexity2015,28,1: | 3 |
| 4 | Arabinose substitution degree in xylan positively affects lignocellulose enzymatic digestibility after various NaOH/H 2 SO 4 pretreatments in Miscanthus显示文摘 | Fengcheng Li Shuangfeng Ren Wei Zhang Zhengdan Xu Guosheng Xie Yan Chen Yuanyuan Tu Qing Li Shiguang Zhou Yu Li Fen Tu Lin Liu Yanting Wang Jianxiong Jiang Jingping Qin Shizhong Li Qiwei Li Hai-Chun Jing Fasong Zhou Neal Gutterson Liangcai Peng | 2012 | Bioresource Technology2012,,: | 1 |
| 5 | Formation of CdS Nanoparticles Within Modified MCM-41 and SBA-15 显示文摘 | Xu Wei Liao Yanting Akins D L | 2002 | J Phys Chem B2002,106,11: | 1 |
| 6 | Formation of CdS nanoparticles within modified MCM-41 and SBA 15 显示文摘 | Xu Wei Liao Yanting Daniel L A | 2002 | Journal of Physical Chemistry B2002,106,11: | 1 |
| 7 | LEARNING MULTIVARIATE TIME SERIES CAUSAL GRAPHS BASED ON CONDITIONAL MUTUAL INFORMATION显示文摘Detection and clarification of cause-effect relationships among variables is an important problem in time series analysis.This paper provides a method that employs both mutual information and conditional mutual information to identify the causal structure of multivariate time series causal graphical models.A three-step procedure is developed to learn the contemporaneous and the lagged causal relationships of time series causal graphs.Contrary to conventional constraint-based algorithm, the proposed algorithm does not involve any special kinds of distribution and is nonparametric.These properties are especially appealing for inference of time series causal graphs when the prior knowledge about the data model is not available.Simulations and case analysis demonstrate the effectiveness of the method. | Yuesong WEI Zheng TIAN Yanting XIAO | 2013 | Journal of Systems Science and Systems Engineering2013,22,1: | 1 |
| 8 | Simple fabrication and photocatalytic activity of ZnO particles with different morphologies显示文摘 | Juan Xie Yanting Li Wei Zhao Li Bian Yu Wei | 2010 | Powder Technology2010,,1: | 1 |
| 9 | 查看详情显示文摘 | Xie Juan Li Yanting Zhao Wei | | 0,,1: | 1 |
| 10 | Distribution of aromatic amines,phenols,chlorobenzenes,and naphthalenes in the surface sediment of the Dianchi Lake,China显示文摘Organic pollutants are widespread environmental pollutants with high toxicity,persistence,and bioaccumulation.Our aim was to investigate the distribution of aromatic amines,phenols,chlorobenzenes,and naphthalenes in the surface sediment of the Dianchi Lake,China.Nineteen surface sediment samples were collected from the Dianchi Lake,and 40 types of organic pollutants were analyzed via gas chromatography-mass spectrometry.The total organic pollutant concentrations in the surface sediment of the Dianchi Lake varied from 27.4 to 1.62×10^3 ng/g.The concentrations of phenols were much higher than those in other water bodies but still within a controllable range,whereas the concentrations of the other organic pollutant classes were similar or even lower.The detection ratio of 3-or 4-methylphenol was the highest(100.00%)among the pollutants.The average total organic pollutant concentrations decreased in the following order:Caohai(540 ng/g)>the middle of Waihai(488 ng/g)>the edge of Waihai(351 ng/g)>Haigeng Dam(90.4 ng/g).Pearson analysis showed a strong correlation among 1-methylnaphthalene,2-methylnaphthalene,1,3-dinitronaphthalene,and 1,4-dinitronaphthalene(P<0.01).Caohai,the north lakeshore of Waihai and the south of Waihai showed higher risk because of high concentration;meanwhile,1,4-dichlorobenzene,3-or 4-methylphenol and 1,2,4-trichlorobenzene were mor e likely to cause risks. | Xinyi Hu Ting Yang Chen Liu Jun Jin Bingli Gao Xuejun Wang Min Qi Baokai Wei Yuyu Zhan Tan Chen Hongtao Wang Yanting Liu Dongrui Bai Zhu Rao Nan Zhan | 2020 | Frontiers of Environmental Science & Engineering2020,14,4: | 1 |
| 11 | Hemicelluloses negatively affect lignocellu- lose crystallinity for high biomass digestibility under NaOH and H2SO4 pretreatments in Miscanthus 显示文摘 | Ning Xu Wei Zhang Shuanfeng Ren Fei Liu Chunqiao Zhao Haofeng Liao Zhengdan Xu Jiangfeng Huang Qing Li Ynanyuan Tu Bin Yn Yanting Wang Jianxiang Jiang Jingping Qin Liangcai Peng | 2012 | Biotechnology for Biofu- els2012,5,: | 1 |
| 12 | LEARNING CAUSAL GRAPHS OF NONLINEAR STRUCTURAL VECTOR AUTOREGRESSIVE MODEL USING INFORMATION THEORY CRITERIA显示文摘Detection and clarification of cause-effect relationships among variables is an important problem in time series analysis.Traditional causality inference methods have a salient limitation that the model must be linear and with Gaussian noise.Although additive model regression can effectively infer the nonlinear causal relationships of additive nonlinear time series,it suffers from the limitation that contemporaneous causal relationships of variables must be linear and not always valid to test conditional independence relations.This paper provides a nonparametric method that employs both mutual information and conditional mutual information to identify causal structure of a class of nonlinear time series models,which extends the additive nonlinear times series to nonlinear structural vector autoregressive models.An algorithm is developed to learn the contemporaneous and the lagged causal relationships of variables.Simulations demonstrate the effectiveness of the proposed method. | WEI Yuesong TIAN Zheng XIAO Yanting | 2014 | Journal of Systems Science & Complexity2014,27,6: | 1 |
| 13 | Characterization of Mechanical Properties of Waste Slurry Modified by Recycled Sand and Cement显示文摘In order to study the modification effect of recycled sand on cement reinforced waste slurry(CWS),triaxial test,scanning electron microscope test and X-ray diffraction test were carried out.The mechanical test of recycled sand and cement reinforced waste slurry(RCWS)shows that the deviatoric stress–strain curve of RCWS samples changes from hardening type to softening type with the increase of recycled sand content;the peak stress increases with the increase of recycled sand content;recycled sand can enhance the shear strength of CWS by increasing both cohesion and internal friction angle.The microscopic test shows that recycled sand can improve the structural compactness by cementing with hydrated calcium silicate and can reduce the void ratio and orientation index of RCWS samples.Finally,the mathematical model between shear strength parameters and void ratio is established.The research shows that adding an appropriate amount of recycled sand and cement has a good modification effect on waste slurry.This is an effective method to treat two kinds of construction wastes:construction waste slurry and waste concrete. | Beifeng Lv Na Li Haibo Kang Yanting Wu Ben Li Wei Wang | 2022 | Journal of Renewable Materials2022,10,10: | 0 |
| 14 | Myeloid peroxisome proliferator-activated receptor α deficiency accelerates liver regeneration via IL-6/STAT3 pathway after 2/3 partial hepatectomy in mice显示文摘Background:Liver regeneration is a fundamental process for sustained body homeostasis and liver function recovery after injury.Emerging evidence demonstrates that myeloid cells play a critical role in liver regeneration by secreting cytokines and growth factors.Peroxisome proliferator-activated receptorα(PPARα),the target of clinical lipid-lowering fibrate drugs,regulates cell metabolism,proliferation,and survival.However,the role of myeloid PPARαin partial hepatectomy(PHx)-induced liver regeneration remains unknown.Methods:Myeloid-specific PPARa-deficient(Ppara^(Mye−/−))mice and the littermate controls(Ppara^(fl/fl))were subjected to sham or 2/3 PHx to induce liver regeneration.Hepatocyte proliferation and mitosis were assessed by immunohistochemical(IHC)staining for 5-bromo-2'-deoxyuridine(BrdU)and Ki67 as well as hematoxylin and eosin(H&E)staining.Macrophage and neutrophil infiltration into livers were reflected by IHC staining for galectin-3 and myeloperoxidase(MPO)as well as flow cytometry analysis.Macrophage migration ability was evaluated by transwell assay.The mRNA levels for cell cycle or inflammation-related genes were measured by quantitative real-time RT-PCR(qPCR).The protein levels of cell proliferation related protein and phosphorylated signal transducer and activator of transcription 3(STAT3)were detected by Western blotting.Results:Ppara^(Mye−/−)mice showed enhanced hepatocyte proliferation and mitosis at 32 h after PHx compared with Ppara^(fl/fl)mice,which was consistent with increased proliferating cell nuclear antigen(Pcna)mRNA and cyclinD1(CYCD1)protein levels in Ppara^(Mye−/−)mice at 32 h after PHx,indicating an accelerated liver regeneration in Ppara^(Mye−/−)mice.IHC staining showed that macrophages and neutrophils were increased in Ppara^(Mye−/−)liver at 32 h after PHx.Livers of Ppara^(Mye−/−)mice also showed an enhanced infiltration of M1 macrophages at 32 h after PHx.In vitro,Ppara-deficient bone marrow-derived macrophages(BMDMs)exhibited markedly enhanced migratory capacity and upregulated M1 genes Il6 and Tnfa but downregulated M2 gene Arg1 expressions.Furthermore,the phosphorylation of STAT3,a key transcript factor mediating IL6-promoted hepatocyte survival and proliferation,was reinforced in the liver of Ppara^(Mye−/−)mice after PHx.Conclusions:This study provides evidence that myeloid PPARαdeficiency accelerates PHx-induced liver regeneration via macrophage polarization and consequent IL-6/STAT3 activation,thus providing a potential target for manipulating liver regeneration. | Guomin Xie Yanting Song Na Li Zhenzhen Zhang Xia Wang Ye Liu Shiyu Jiao Ming Wei Baoqi Yu Yan Wang Hua Wang Aijuan Qu | 2022 | Hepatobiliary Surgery and Nutrition2022,11,2: | 0 |
| 15 | Recent progress of fiber-based transistors: materials, structures and applications显示文摘Wearable electronics on fibers or fabrics assembled with electronic functions provide a platform for sensors,displays,circuitry,and computation.These new conceptual devices are human-friendly and programmable,which makes them indis-pensable for modern electronics.Their unique properties such as being adaptable in daily life,as well as being lightweight and flexible,have enabled many promising applications in robotics,healthcare,and the Internet of Things(IoT).Transistors,one of the fundamental blocks in electronic systems,allow for signal processing and computing.Therefore,study leading to integration of transistors with fabrics has become intensive.Here,several aspects of fiber-based transistors are addressed,including materials,system structures,and their functional devices such as sensory,logical circuitry,memory devices as well as neuromorphic computation.Recently reported advances in development and challenges to realizing fully integrated electronic textile(e-textile)systems are also discussed. | Haozhe Zhang Zhe Wang Zhixun Wang Bing He Mengxiao Chen Miao Qi Yanting Liu Jiwu Xin Lei Wei | 2022 | Frontiers of Optoelectronics2022,15,1: | 0 |
| 16 | Four temporin-derived peptides exhibit antimicrobial and antibiofilm activities against methicillin-resistant Staphylococcus aureus显示文摘Temporin-GHa(GHa)was cloned from Hylarana guentheri,showing a weak antimicrobial activity.In order to improve its bactericidal efficacy,GHaR6R,GHaR7R,GHaR8R and GHaR9W were designed and synthesized.Compared to the parent peptide,the GHa-derived peptides show potent antimicrobial activities against methicillin-resistant Staphylococcus aureus(MRSA),which is the main pathogen with high morbidity and mortality that causes various infections in humans.These peptides exert bactericidal actions on MRSA by permeabilizing the cytoplasmic membranes and damaging membrane integrity.All of the four peptides exhibit excellent stability under harsh conditions,including extreme temperature and salts.Furthermore,they inhibit the formation of biofilm and eradicate mature biofilm of MRSA.The GHa-derived peptides decrease bacterial surface hydrophobicity,autoaggregation and polysaccharide intercellular adhesion synthesis in concentration-dependent manner.Real-time quantitative reverse transcription PCR analysis revealed that the peptides downregulatethe expression of adhesion genes icaADBC involved in biofilm formation.Except for GHaR7R,the other three peptides have low hemolytic toxicity against human erythrocytes.In the presence of human erythrocytes,GHaR7R,GHaR8R and GHaR9W interact with MRSA preferentially.GHaR6R,GHaR8R and GHaR9W show less toxicity toward normal cells HL-7702 and hFOB1.19.These results suggest that the GHa-derived peptides may be promising antimicrobial candidates against MRSA infections. | Xiuchuan Tan Shenghong Xie Xiao Jin Ruiying Zhu Shuangshuang Wei Yanting Song Xi Xie Rong Wang Lushuang Li Manchuriga Wang Yingxia Zhang | 2022 | Acta Biochimica et Biophysica Sinica2022,54,3: | 0 |
| 17 | A review of condition-based maintenance: Its prognostic and operational aspects显示文摘Condition-based maintenance(CBM)detects early signs of failure and dictates when maintenance should be performed based on the actual condition of a system.In this paper,we first review some of the recent research on CBM under various physical structures and signal data.Then,we summarize several kinds of prognostic models that use monitoring information to estimate the reliability of complex systems or products.Monitoring information also facilitates operational decisions in production planning,spare parts management,reliability improvement,and prognostics and health management.Finally,we suggest some research opportunities for the reliability and operations management communities to fill the research gap between these two fields. | Yanrong LI Shizhe PENG Yanting LI Wei JIANG | 2020 | Frontiers of Engineering Management2020,7,3: | 0 |