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| 1 | Towards 6G wireless communication networks:vision,enabling technologies,and new paradigm shifts显示文摘The fifth generation(5G)wireless communication networks are being deployed worldwide from 2020 and more capabilities are in the process of being standardized,such as mass connectivity,ultra-reliability,and guaranteed low latency.However,5G will not meet all requirements of the future in 2030 and beyond,and sixth generation(6G)wireless communication networks are expected to provide global coverage,enhanced spectral/energy/cost efficiency,better intelligence level and security,etc.To meet these requirements,6G networks will rely on new enabling technologies,i.e.,air interface and transmission technologies and novel network architecture,such as waveform design,multiple access,channel coding schemes,multi-antenna technologies,network slicing,cell-free architecture,and cloud/fog/edge computing.Our vision on 6G is that it will have four new paradigm shifts.First,to satisfy the requirement of global coverage,6G will not be limited to terrestrial communication networks,which will need to be complemented with non-terrestrial networks such as satellite and unmanned aerial vehicle(UAV)communication networks,thus achieving a space-airground-sea integrated communication network.Second,all spectra will be fully explored to further increase data rates and connection density,including the sub-6GHz,millimeter wave(mmWave),terahertz(THz),and optical frequency bands.Third,facing the big datasets generated by the use of extremely heterogeneous networks,diverse communication scenarios,large numbers of antennas,wide bandwidths,and new service requirements,6G networks will enable a new range of smart applications with the aid of artificial intelligence(AI)and big data technologies.Fourth,network security will have to be strengthened when developing 6G networks.This article provides a comprehensive survey of recent advances and future trends in these four aspects.Clearly,6G with additional technical requirements beyond those of 5G will enable faster and further communications to the extent that the boundary between physical and cyber worlds disappears. | Xiaohu YOU Cheng-Xiang WANG Jie HUANG Xiqi GAO Zaichen ZHANG Mao WANG Yongming HUANG Chuan ZHANG Yanxiang JIANG Jiaheng WANG Min ZHU Bin SHENG Dongming WANG Zhiwen PAN Pengcheng ZHU Yang YANG Zening LIU Ping ZHANG Xiaofeng TAO Shaoqian LI Zhi CHEN Xinying MA Chih-Lin I Shuangfeng HAN Ke LI Chengkang PAN Zhimin ZHENG Lajos HANZO Xuemin(Sherman)SHEN Yingjie Jay GUO Zhiguo DING Harald HAAS Wen TONG Peiying ZHU Ganghua YANG Jun WANG Erik GLARSSON Hien Quoc NGO Wei HONG Haiming WANG Debin HOU Jixin CHEN Zhe CHEN Zhangcheng HAO Geoffrey Ye LI Rahim TAFAZOLLI Yue GAO HVincent POOR Gerhard P.FETTWEIS Ying-Chang LIANG | 2021 | Science China(Information Sciences)2021，64，1： | 122 |
| 2 | Quercetin induces apoptosis by activating caspase-3 and regulating Bcl-2 and cyclooxygenase-2 pathways in human HL-60 cells显示文摘橡黄素是自然地发生之一饮食的黄酮醇混合物。它在植物富有地是在场的并且有 chemopreventive 和 anticancer 效果。调查它的 anticancer 机制,我们对尖锐白血病房间线检验了橡黄素的活动, HL-60。我们的结果证明橡黄素禁止了房间增长并且在一个时间依赖者和剂量依赖者举止导致了 apoptosis。而且,橡黄素下面调整 anti-apoptosis 蛋白质 Bcl-2 的表示并且起来调整 pro-apoptosis 蛋白质 Bax 的表示。Caspase-3 被橡黄素也激活,它开始了一条 caspase-3-depended mitochodrial 小径导致 apoptosis。橡黄素禁止了 cycloocygenase-2 (Cox-2 ) 的表示,这也被发现 mRNA 和 Cox-2 蛋白质。一起拿,这些调查结果建议橡黄素由禁止 Cox-2 表示在一条 caspase-3-dependent 小径导致 apoptosis 并且调整下游的 apoptotic 部件的表示,包括 Bcl-2 和 Bax。橡黄素能是可能安全地在白血病治疗被使用的一个有势力和有希望的药。 | Guomin Niu Songmei Yin Shuangfeng Xie Yiqing Li Danian Nie Liping Ma Xiuju Wang Yudan Wu | 2011 | Acta Biochimica et Biophysica Sinica2011，43，1： | 28 |
| 3 | Characterization of MR-1,a Novel Myofibrillogenesis Regulator in Human Muscle显示文摘The actin-myosin contractile apparatus consists of several thick filament and thin filament proteins. Specific regulatory mechanisms are involved in this highly ordered process. In this paper, we reported the identification and characterization of a novel myofibrillogenesis regulator, MR-1. The MR-1 gene was cloned from human skeletal muscle cDNA library by using a strategy that involves EST data base searching, PCR and RACE. The MR-1 gene is located on human chromosome 2q35 and encodes a 142 aa protein. Northern blot revealed that the mRNA level of MR-1 was highest in the skeletal muscle and certain level of MR-1 expression was also observed in heart, liver and kidney. Immunohistochemical assay confirmed that the MR-1 protein existed in human myocardial myofibrils. It was found by yeast two-hybrid screening and confirmed by in vitro binding assay that MR-1 could interact with sarcomeric proteins, such as myosin regulatory light chain, myomesin 1 and β-enolase. These studies suggested that MR-1 might play a regulatory role in the muscle cell and it was worth investigating further. | Tian-BoLI Xiu-HuaLIU ShuangFENG YangHU Wei-XiYANG YueHAN Yi-GuangWANG Li-MinGONG | 2004 | Acta Biochimica et Biophysica Sinica2004，36，6： | 13 |
| 4 | Space experimental studies of microgravity fluid science in China显示文摘Microgravity fluid physics is an important part of microgravity sciences, which consists of simple fluids of many new systems, gas-liquid two-phase flow and heat transfer, and complex fluid mechanics. In addition to the importance of itself in sciences and applications, microgravity fluid physics closely relates to microgravity combustion, space biotechnology and space materials science, and promotes the developments of interdisciplinary fields. Many space microgravity experiments have been performed on board the recoverable satellites and space ships of China and pushed the rapid development of microgravity sciences in China. In the present paper, space experimental studies and the main results of the microgravity fluid science in China in the last 10 years or so are introduced briefly. | HU WenRui LONG Mian KANG Qi XIE JingChang HOU MeiYing ZHAO JianFu DUAN Li WANG ShuangFeng | 2009 | Chinese Science Bulletin2009，54，22： | 10 |
| 5 | SKP2 siRNA inhibits the degradation of P27^kip1 and down-regulates the expression of MRP in HL-60/A cells显示文摘S 阶段联系 kinase 的蛋白质 2 (SKP2 ) 基因是肿瘤 suppressor 基因,并且涉及 P27kip1 的调停 ubiquitin 的降级。SKP2 和 P27kip1 影响通过调整白血病房间的增长, apoptosis 和区别继续和白血病的预后。在这研究,我们探索了通过 SKP2 下面规定 HL-60/A 药抵抗逆行的机制。HL-60/A 房间是由有 SKP2 siRNA 的 Amaxa Nucleofector 系统的 nucleofected。Skp2, P27kip1,和多药抵抗的基因和蛋白质表示层次联系了蛋白质(MRP ) 被反向的抄写聚合酶链反应和西方的污点分析分别地决定。房间周期被流动 cytometry 分析。50% 禁止的集中价值在 chemotherapeutics 的不同集中下面根据这些二种房间的死亡率用细胞毒素的分析被计算比较房间的敏感。HL-60/A 房间显示出由抗力移转特征的多药抵抗显型到 adriamycin, daunorubicin,和 arabinosylcytosine,由于 MRP 的表示。我们发现 SKP2 的表示比在 HL-60 房间在 HL-60/A 房间是更高的,但是 P27kip1 的表示更低。而 P27kip1 的蛋白质水平是起来调整的,在由 SKP2 siRNA 的 HL-60/A 房间 nucleofected 的 SKP2 的表示是下面调整的。与在控制组(由控制 siRNA 的 nucleofected ) 的 MRP 表达式水平相比, mRNA 和蛋白质表达式由 SKP2 siRNA 在 HL-60/A 房间 nucleofected MRP 铺平更低,并且后者房间对 adriamycin, daunorubicin,和 arabinosylcytosine 更敏感。下面调整在 G0/G1 阶段的 SKP2 表示和逮捕房间与下面调整的 MRP 改进白血病房间的药敏感表示。 | Jie Xiao Songmei Yin Yiqing Li Shuangfeng Xie Danian Nie Liping Ma Xiuju Wang Yudan Wu Jianhong Feng | 2009 | Acta Biochimica et Biophysica Sinica2009，41，8： | 7 |
| 6 | A Xanthomonas oryzae pv. oryzae effector, Xop R, associates with receptor-like cytoplasmic kinases and suppresses PAMP-triggered stomatal closure显示文摘Receptor-like kinases(RLKs) play important roles in plant immunity signaling; thus, many are hijacked by pathogen effectors to promote successful pathogenesis. Xanthomonas oryzae pv. oryzae(Xoo) is the causal agent of rice leaf blight disease. The strain PXO99 A has 18 non-TAL(transcription activation-like) effectors; however, their mechanisms of action and host target proteins remain largely unknown. Although the effector XopR from the Xoo strain MAFF311018 was shown to suppress PAMP-triggered immune responses in Arabidopsis, its target has not yet been identified. Here, we show that PXO99 A XopR interacts with BIK1 at the plasma membrane. BIK1 is a receptor-like cytoplasmic kinase(RLCK) belonging to the RLK family of proteins and mediates PAMP-triggered stomatal immunity. In turn, BIK1 phosphorylates XopR. Furthermore, XopR suppresses PAMP-triggered stomatal closure in transgenic Arabidopsis expressing XopR. In addition, XopR is able to associate with RLCKs other than BIK1. These results suggest that XopR likely suppresses plant immunity by targeting BIK1 and other RLCKs. | Shuangfeng Wang Jianhang Sun Fenggui Fan Zhaoyun Tan Yanmin Zou Dongping Lu | 2016 | Science China(Life Sciences)2016，59，9： | 6 |
| 7 | Treatment of rotaviral gastroenteritis with Qiwei Baizhu powder显示文摘AIM To observe the effects of Qiwei Baizhu Powder ( QWBZP) on rotaviral gastroenteritis in children and in animal models.``METHODS Enrolled patients were divided into two groups, and one group was treated with oral rehydration solution(ORS) and the other treated with oral liquid of QWBZP. Neonate mice were orally infected with 50 μLrotavirus suspension (4 × l0s PFU/mL) and treated with ORS or oral liquid of QWBZP, respectively.``RESULTS Eighty-three cases of rotaviral gastroenteritis treated with QWBZP revealed a better efficacy than that treated with ORS (x2 - 10.8T, P<0.05). The contents of sodium and glucose as well as number of patients with positive human rotavirus antigen in stool in QWBZP group were all less than that in ORS group. In animal models,QWBZP was found effective in treating rotavirus gastroenteritis in neonate NIH mice, as compared with control groups. In QWBZP group, the mortality of infected mice was decreased by 73.3%, the body weight of infected mice was increased, the contents of sodium and glucose as well as number of mice with positive rotavirus antigen in feces were significantly reduced, and the pathological changes such as damage of small intestinal mucosa and villi were also obviously alleviated.``CONCLUSION QWBZP has effects on improving the absorptive function of small intestine, shortening the duration of diarrhea and rotavirus shedding from stool and alleviating the pathological changes of small intestine induced by rotavirus. | Shuang-Teng He~1 Fei-Zhou He~2 Can-Rong Wu~3 Shun-Xiang Li~2 Wei-Xin Liu~4 Yong-Fang Yang~2 Shi-Sheng Jiang~2 Gang He~1 1 Institute of Combined Traditional Chinese and Western Medicine,Xiangya Hospital,Hunan Medical University,Changsha,410008,China2 Hunan Province Academy of Traditional Chinese Medicine,Changsha 410006,China3 Department of Microbiology,Hunan College of Traditional Chinese Medicine,Changsha 410007,China4 Department of Pediatrics,The Second Hospital of Shuangfeng County,Hunan Province,411700,China | 2001 | World Journal of Gastroenterology2001，7，5： | 6 |
| 8 | Three Cases of COVID-19 Variant Delta With and Without Vaccination——Chengdu City,Sichuan Province,April-May,2021显示文摘On April 26,2021,a 33-year-old male Chinese sailor returning from India via Kathmandu,Nepal,tested positive for the coronavirus disease 2019(COVID-19)by Chengdu Customs and was confirmed positive by Chengdu CDC(Case A).On May 2,2021,a housewife in the same flight tested positive for COVID-19 by Pengzhou CDC in Sichuan Province during her quarantine period and was confirmed positive by Chengdu CDC the next day(Case B). | Heng Chen Yi Mao Zhenhua Duan Liang Wang Yue Cheng Yingxue Dai Haixia Luo Wenjun Xie Shuangfeng Fan Yuzhen Zhou Jingpei Xu Lan Feng Liwen Hu Zhu Liu Xian Liang Liangshuang Jiang Xiaoli Tuo | 2021 | China CDC weekly2021，3，25： | 5 |
| 9 | Atomistic insight into ordered defect superstructures at novel grain boundaries in CuO nanosheets: From structures to electronic properties显示文摘Determining atomistic structures of grain boundaries (GBs) is essential to understand structure--property interplay in oxides.Here,different GB superstructures in CuO nanosheets,including (111) and (114) twinning boundaries (TBs) and (002)/(223) GB,are investigated.Unlike the lower-energy stoichiometric (111) TB,both experimental and first-principles investigations reveal a severe segregation of Cu and O vacancies and a nonstoichiometric property at (114) TB,which may facilitate ionic transportation and provide space for elemental segregation.More importantly,the calculated electronic structures have shown the increased conductivity as well as the unanticipated magnetism in both (114) TB and (002)/(223) GB.These findings could contribute to the race towards the property-directing structural design by GB engineering. | Lulu Zhao Lei Li Huaping Sheng He Zheng Shuangfeng Jia Weiwei Meng Huihui Liu Fan Cao Huayu Peng Jianbo Wang | 2019 | Nano Research2019，12，5： | 5 |
| 10 | Experimental study on microcapsule fluid oscillating heat pipe显示文摘In this experiment,a four-turn oscillating heat pipe(OHP)is made of copper tube with an inner diameter of 1.3mm,and an outer diameter of 2.5mm.A series of experiments are performed to investigate the startup characteristics of OHP,and the effects of different working fluids(FS-39E microcapsule fluid,pure water,ethanol),different liquid filling rates(40%-80%)on the heat transport capability of OHP in vertical bottom heat mode.The results show that the startup of OHP is relative with liquid filling rate,thermal driving force and working fluid;and experiences different flow patterns with the increase of heat load.The best concentration of FS-39E microcapsule fluid is 1wt%.While FS-39E microcapsule fluid is used as the working fluid,compared with pure water and ethanol,the OHP has a broader working scope;when the liquid filling rate is relatively high,the OHP shows a better performance on the startup and heat transport capability. | LIN ZiRong WANG ShuangFeng ZHANG WeiBao | 2009 | Science China(Technological Sciences)2009，52，6： | 5 |
| 11 | Preparation and phase change performance of Na_2HPO_4·12H_2O@poly(lactic acid) capsules for thermal energy storage显示文摘Micro-encapsulated phase-change materials(micro PCMs) with Na_2 HPO_4·12 H_2 O encapsulated in poly(lactic acid)(PLA) shell were prepared by a solvent evaporation–precipitation method that involves the use of a coaxial needle. The effects of PLA concentration, stirring speed, injection rate of core and shell solutions, and polyvinyl alcohol(PVA) concentration on phase change properties were investigated. The thermal properties of microP CMs were characterized by differential scanning calorimetry(DSC). The capsules prepared under the optimal conditions are about 2 mm in diameter and show a latent heat of up to 122.2 J·g^(-1). | Na Fan Lang Chen Guoyong Xie Donghong Yin Chak-Tong Au Shuangfeng Yin | 2019 | Chinese Journal of Chemical Engineering2019，27，3： | 4 |
| 12 | Atomic-scale observation of a two-stage oxidation process in Cu2O显示文摘Cu 2 O nanocrystallines (NC ) 直接被观察由在 situ 高分辨率的传播电子显微镜学。一个二阶段的氧化过程被观察:(1 ) 起始的氧化阶段被 Cu 2 经由稳固固体的转变的 O NC,导致一个新中间的 CuO x 阶段的形成。CuO x 阶段的可能的水晶结构被讨论。(2 ) 随后, CuO x 被 layer-by-layer 氧化转变成 CuO。这些结果将在理解铜氧化物的氧化机制帮助并且为改进他们的结构的差异并且利用他们的潜在的工业应用铺平道路。 | Huihui Liu He Zheng Lei Li Huaping Sheng Shuangfeng Jia Fan Cao Xi Liu Boyun Chen Ru Xing Dongshan Zhao Jianbo Wang | 2017 | Nano Research2017，10，7： | 4 |
| 13 | Numerical study on effects of the cofferdam area in liquefied natural gas storage tank on the leakage and diffusion characteristics of natural gas显示文摘The leakage and diffusion characteristics of natural gas were investigated in the condition of the leakage of liquefied natural gas(LNG) in the storage tank.Fluent was adopted to simulate the process in a series of three-dimension unsteady state calculations.The effects of different heights of the cofferdam(1.0 m, 2.0 m and 3.0 m),wind directions,ambient temperature,leakage location,leakage volume on the diffusion process of natural gas were investigated.The diffusion characteristics of the natural gas clouds over cofferdam were found.Under windless condition,when the gas clouds met,the gas clouds rose due to the collision,which made them easier to cross the cofferdam and spread out.The higher the ambient temperature was,the higher the gas concentration around the cofferdam was,and the smaller the gas concentration difference was.When the leakage occurred,the higher coffe rdam was more beneficial to delay the outward diffusion of gas clouds.However,when the leaka ge stopped,the higher cofferdam went against the dissipation of gas clouds.Under windy condition,the time to form stable leakage flow field was faster than that of windless,and the lower cofferdam further reduced this time.Therefore,considering the effect of barrier and dissipation,it was suggested that the rational height of cofferdam should be designed in the range of 1.0 m to 2.0 m.In case of emergency,the leakage of gas should be deduced reasonably by combining the measurement of gas concentration with the rolling of gas clouds.When windless,the leakage area should be entered between the overflows of gas clouds. | Zirong Lin Shuangfeng Wang Shuxun Fu Jiepeng Huo | 2021 | Chinese Journal of Chemical Engineering2021，34，1： | 2 |
| 14 | UAV safe route planning based on PSO-BAS algorithm显示文摘In order to solve the current situation that unmanned aerial vehicles(UAVs)ignore safety indicators and cannot guarantee safe operation when operating in low-altitude airspace,a UAV route planning method that considers regional risk assessment is proposed.Firstly,the low-altitude airspace is discretized based on rasterization,and then the UAV operating characteristics and environmental characteristics are combined to quantify the risk value in the low-altitude airspace to obtain a 3D risk map.The path risk value is taken as the cost,the particle swarm optimization-beetle antennae search(PSO-BAS)algorithm is used to plan the spatial 3D route,and it effectively reduces the generated path redundancy.Finally,cubic B-spline curve is used to smooth the planned discrete path.A flyable path with continuous curvature and pitch angle is generated.The simulation results show that the generated path can exchange for a path with a lower risk value at a lower path cost.At the same time,the path redundancy is low,and the curvature and pitch angle continuously change.It is a flyable path that meets the UAV performance constraints. | ZHANG Honghong GAN Xusheng LI Shuangfeng CHEN Zhiyuan | 2022 | Journal of Systems Engineering and Electronics2022，33，5： | 2 |
| 15 | The role of AMP-activated protein kinase in quercetin-induced apoptosis of HL-60 cells显示文摘我们的以前的研究证明了橡黄素禁止 Cox-2 和 Bcl-2 表情,并且导致人的白血病 HL-60 cellapoptosis。以便在 HL-60cells 的导致橡黄素的 apoptosis 上调查激活安培的蛋白质 kinase (AMPK ) 的角色,我们使用了流动 cytometry 检测房间 apoptosis。LKB1, phosphorylated AMPK (p-AMPK ) ,和 Cox-2 proteinwere 的表情由西方的污点在 HL-60 房间和正常的外部血 mononuclear 房间(PBMC ) 检测了。LKB1, p-AMPK,和 Cox-2 的表情与橡黄素在文化以后在 HL-60 房间被检测。p-AMPK 的表情与 AMPK 禁止者混合物 C 在文化以后在 HL-60cells 被检测。然后, LKB1, p-AMPK,和 Cox-2 的表情与独自一个的橡黄素或橡黄素 + 混合物 C 在文化以后在 HL-60cells 被检测。在 PBMC 和 HL-60 之间没有重要 differencein LKB1,这被发现。在 PBMC 的 p-AMPK 在 HL-60 比那高,当 Cox-2 更低时。在 HL-60with 橡黄素的文化以后, p-AMPK 被增加, Cox-2 被减少,但是 LKB1 仍然保持未改变。在有 CompoundC 的 HL-60 的文化以后, p-AMPK 被减少。在 LKB1 在之间没有重要差别橡黄素独自一个并且橡黄素 + CompoundC 组。p-AMPK 更显著地减少了,当 Cox-2 在橡黄素 + 混合物 C groupsthan 更显著地增加了时那些在橡黄素独自一个的组。一起拿,这些调查结果建议橡黄素激活独立于 LKB1 激活的 AMPK expressionin HL-60 房间,由激活 AMPK 禁止 Cox-2 表示,并且进一步调整施加它的反白血病效果的 apoptosis 的 Bcl-2-dependentpathways。 | Jie Xiao Guomin Niu Songmei Yin Shuangfeng Xie Yiqing Li Danian Nie Liping Ma Xiuju Wang Yudan Wu | 2014 | Acta Biochimica et Biophysica Sinica2014，46，5： | 2 |
| 16 | Controller design for networked control system with data packet dropout and transmission delays显示文摘In this paper, the stabilization problem for a class of networked control systems (NCSs) with data packet dropouts and transmission time delays is considered, where the delays are time-varying and uncertain, the data packet dropout is modeled as a two-state Markov chain. To compensate the lost packet, a data packet dropout compensator is established. Thus a more realistic model for such NCSs is presented. Sufficient conditions for the stabilization of the new resulting system are derived in the form of linear matrix inequalities (LMIs). Numerical example illustrates the solvability and effectiveness of the results. | Xinping GUAN Shuangfeng DAI Chengnian LONG | 2007 | 控制理论与应用(英文版)2007，5，3： | 2 |
| 17 | Involvement of levels of Toll like receptor-4 in monocytes, CD4+ T-lymphocyte subsets, and cytokines in patients with immune thrombocytopenic purpura显示文摘 | Hongyun Liu Xianfeng Ouyang Yiqing Li Hua Zeng Xiuju Wang Shuangfeng Xie Danian Nie Jie Xiao Jing Wei Yudan Wu Songmei Yin Liping Ma | 2013 | Thrombosis Research2013，，： | 2 |
| 18 | Heat transfer enhancement of micro oscillating heat pipes with self-rewetting fluid显示文摘 | Hu Yanxin Liu Tengqing Wang Shuangfeng | 2014 | International Journal of Heat and Mass Transfer2014，70，： | 1 |
| 19 | Suboptimal Transmission of Orthogonal Space-time Block Codes over Correlated Distributed Antennas显示文摘 | Han Shuangfeng Zhou Shidong Wang Jing | 2007 | Signal Processing Letters2007，14，2： | 1 |
| 20 | Numerical study on a slit fm-and-tube heat exchanger withlongitudinal vortex generators显示文摘 | Li Jiong Wang Shuangfeng Chen Jinfang | 2011 | International Journal ofHeat and Mass Transfer2011，54，2： | 1 |
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