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| 1 | Retinal structural-vascular-functional relationship using optical coherence tomography and optical coherence tomography -angiography in myopia显示文摘Background:To examine the retinal structure–vascular-function relationship using optical coherence tomography(OCT)and optical coherence tomography angiography(OCTA)in myopia.Methods:This was a prospective cross-sectional study comprising 86 eyes of 45 individuals with varying axial lengths and spherical equivalents and no posterior segment abnormalities.All eyes underwent optical coherence tomography with the Spectralis SD-OCT and OCTA with RTVue-XR Avanti;Optovue.Individual macular retinal layer thicknesses and flow areas and vessel densities were measured on OCT and OCTA,respectively.Linear correlations were made between the macular layer thicknesses,flow areas and vessel densities with axial length,spherical equivalent and visual acuity.Results:The participants’mean ages were 33.34±14.45 years,mean spherical equivalent refractions were−7.17±5.71 D and axial lengths were 25.95±2.41 mm.There were significant positive correlations of foveal angle(r=0.757,p=0.001),inner retinal(r=0.764,p=0.001)and outer plexiform layer(r=0.771,p=0.001)thickness on OCT and vessel densities in deep capillary plexus(r=0.313,p=0.003)on OCTA with axial length and negative correlations with spherical equivalents and visual acuity.Significant negative correlations of outer nuclear layer(r=−0.560,p=0.03)and photoreceptor outer segment layer thickness(r=−0.856,p<0.001)were noted on OCT with axial length and positive correlations with spherical equivalents and visual acuity.Conclusion:The lateral retinal stretching in myopia could possibly explain the correlation between retinal layer thickness,vascular density and visual acuity in these eyes.Further research is required to investigate this. | Ramesh Venkatesh Shivani Sinha Deepika Gangadharaiah Santosh G.K.Gadde Ashwin Mohan Rohit Shetty Naresh Kumar Yadav | 2019 | Eye and Vision2019，6，1： | 7 |
| 2 | Novel chemical scaffolds of the tumor marker AKRIBIO inhibitors discovered by 3D QSAR pharmacophore modeling显示文摘目的: 最近的证据建议 aldo-keto reductase 家庭 1 B10 (AKR1B10 ) 可以是禁止者为人的癌症的许多类型的治疗为一种有希望的选择提供的人的肿瘤,和那 AKR1B10 的一个潜在的诊断或预示的标记。这研究的目的是识别在 silico 途径使用的 AKR1B10 禁止者的新奇化学脚手架。 | Raj KUMAR Minky SON Rohit BAVI Yuno LEE Chanin PARK Venkatesh ARULALAPPERUMAL Guang Ping CAO Hyong-ha KIM Jung-keun SUH Yong-seong KIM Yong Jung KWON Keun Woo LEE | 2015 | Acta Pharmacologica Sinica2015，36，8： | 4 |
| 3 | A comparative study of variable angle volar plate and bridging external fixator with K-wire augmentation in comminuted distal radius fractures显示文摘Purpose:Comminuted intraarticular distal radial fractures are difficult to treat conservatively and require operative treatment.This study compared the functional outcomes between variable angle volar plating and external fixator with K-wire augmentation in open reduction and internal fixation.Methods:A total of 62 adult patients with comminuted intraarticular distal radius fracture were randomized into 2 groups:volar plate group and external fixator group.These patients aged between 18 and 60 years had unilateral fractures,and agreed to be included in the study.Patients with a history of fracture,bilateral fracture,associated other injuries,delayed injury for more than 2 weeks,open fracture,pre-existing arthrosis or disability,psychiatric illness and pathological fracture were excluded.Patients were followed up at 6 weeks,3 months,6 months and 1 year.The assessment of pain,functional activity,range of motion and grip strength was done at each stage of follow-up.The pain and functional activities were assessed by patient rated wrist evaluation(PRWE)score and disabilities of the arm,shoulder and hand(DASH)score.Results:Patients in volar plate group had superior PRWE score and DASH score at each stage of followup.At 1 year follow-up,the mean PRWE score were 7.48 for volar plate group and 7.35 for external fixator group;while the mean DASH score was 4.65 for volar plate group and 5.61 for external fixator group.They had better flexion and extension range of movement.They also had better pronation and supination range of motion at initial follow-up,however the difference get attenuated by 1 year.Volar plate group had significantly better grip strength than external fixator group.Complication rates were higher in external fixation group.Conclusion:Fixation with variable angle volar plate results in early wrist mobilization,better range of movement,less pain and disability and early return of function. | Ratish Kumar Mishra Bhagwati Prasad Sharma Amit Kumar Rohit Sherawat | 2021 | Chinese Journal of Traumatology2021，24，5： | 3 |
| 4 | 游走脾:手术之謎显示文摘Wandering spleen,also referred to as‘ptotic spleen’,is a rare clinical condition characterized by splenicmigration form its normal left hypochondrial position to any other abdominal or pelvic position.Among themultifactorial etiologies proposed,laxity of the spleen’s primary supporting ligaments is themost agreed-upon hypothesis.We present one rare case of wandering spleen in an 11-year-old girl who presented with recurrent abdominal pain with no localizing features.Her abdominal examination revealed an intra-abdominal left iliac fossa lump with restrictedmobility,which was confirmed as a wandering spleen by abdominal sonography and contrast-enhanced computed tomography.Intraoperatively,an infarcted spleen was encountered with tortuous,elongated,torsional splenic pedicle and a single dense adhesive band with descending colon.Splenectomy was offered to the patient.Post-operatively,the patient is healthy and symptom free at one-year follow-up.The rare clinical diagnosis of this condition,particularly in the paediatric age-group,makes it an enigma for the surgical world. | Ashok Kumar Puranik Rohit Mehra Sushila Chauhan Rahul Pandey | 2017 | Gastroenterology Report2017，5，3： | 2 |
| 5 | Adder design using a 5-input majority gate in a novel “multilayer gate design paradigm” for quantum dot cellular automata circuits显示文摘This paper proposes a novel design paradigm for circuits designed in quantum dot cellular automata(QCA) technology.Previously reported QCA circuits in the literature have generally been designed in a single layer which is the main logical block in which the inverter and majority gate are on the base layer,except for the parts where multilayer wire crossing was used.In this paper the concept of multilayer wire crossing has been extended to design logic gates in multilayers.Using a 5-input majority gate in a multilayer,a 1-bit and 2-bit adder have been designed in the proposed multilayer gate design paradigm.A comparison has been made with some adders reported previously in the literature and it has been shown that circuits designed in the proposed design paradigm are much more efficient in terms of area,the requirement of QCA cells in the design and the input-output delay of the circuit.Over all,the availability of one additional spatial dimension makes the design process much more flexible and there is scope for the customizability of logic gate designs to make the circuit compact. | Rohit Kumar Bahniman Ghosh Shoubhik Gupta | 2015 | Journal of Semiconductors2015，36，4： | 2 |
| 6 | Assessment of quadriceps muscle thickness using bedside ultrasonography by nurses and physicians in the intensive care unit:Intra- and inter-operator agreement显示文摘BACKGROUND Data regarding the agreement among multiple operators for measurement of quadriceps muscle thickness by bedside ultrasonography(USG)are sparse.AIM To statistically assess the agreement among 5 operators for measurement of quadriceps muscle thickness on bedside USG.METHODS This was a cross-sectional observational study.The 5 operators of varied experience(comprised of 1 critical care consultant,2 fellows,and 2 nurses)independently measured quadriceps muscle thickness in triplicate for 45 critically ill patients each,using USG.Intra-and interrater agreement rates among the 5 operators were assessed using intraclass correlation coefficient(ICC)and expressed with 95%confidence interval(CI).RESULTS The 5 operators produced a total of 135 readings and 675 observations for ICC calculations to determine the intraoperator and interoperator variations respectively.For intraoperator agreement,the overall ICC(95%CI)was 0.998(0.997,0.999)for operator 1,0.998(0.997,0.999)for operator 2,0.997(0.995,0.999)for operator 3,0.999(0.998,0.999)for operator 4,and 0.998(0.997,0.999)for operator 5.For interoperator agreement,the overall ICC(95%CI)was 0.977(0.965,0.986;P<0.001)for reading 1,0.974(0.960,0.984;P<0.001)for reading 2,and 0.975(0.961,0.985;P<0.001)for reading 3.CONCLUSION USG measurement of quadriceps muscle thickness was not dependent on clinical experience,supporting training for nurses in it. | Rohit Kumar Tajamul Hussain Shah Vijay Hadda Pawan Tiwari Saurabh Mittal Karan Madan Maroof Ahmad Khan Anant Mohan | 2019 | World Journal of Critical Care Medicine2019，8，7： | 2 |
| 7 | Functionalization of poly( o -phenylenediamine) with gold nanoparticles as a label-free immunoassay platform for the detection of human enterovirus 71显示文摘 | Yong Kong Juan Li Shun Wu Wen Cheng Rohit Kumar Rana Jun-Jie Zhu | 2013 | Sensors & Actuators: B Chemical2013，，： | 1 |
| 8 | Targeting the STAT3 signaling pathway in cancer: Role of synthetic and natural inhibitors显示文摘 | Kodappully Sivaraman Siveen Sakshi Sikka Rohit Surana Xiaoyun Dai Jingwen Zhang Alan Prem Kumar Benny K.H. Tan Gautam Sethi Anupam Bishayee | 2014 | BBA - Reviews on Cancer2014，，2： | 1 |
| 9 | Novel Z-Scheme ZnIn_(2)S_(4)-based photocatalysts for solar-driven environmental and energy applications: Progress and perspectives显示文摘Benefiting from strong redox ability,improved charge transport,and enhanced charge separation,Zscheme heterostructures of ZnIn_(2)S_(4) based photocatalysts have received considerable interest to tackle energy needs and environmental issues.The present review highlights the properties of ZnIn_(2)S_(4),which make it a promising photocatalyst,and a suitable combination with oxidation photocatalyst to form Zscheme,leading to improve their photocatalytic properties dramatically.As the central part of this review,various types of Z-scheme heterojunction developed recently based on ZnIn_(2)S_(4) and their application in pollutant degradation,water splitting,CO_(2) reduction,and toxic metals remediation.Some analytical techniques to detect or trap the active radical and study the charge separation and lifetime of charge carriers in these Z-schemes are highlighted.This review offers its readers a broad optical window for the structural architecture of ZnIn_(2)S_(4)-based Z-schemes,photocatalytic activity,stability,and their technological applications.Finally,we discuss the challenges and opportunities for further development on Z-Scheme ZnIn_(2)S_(4)-based photocatalysts toward energy and environmental applications based on the recent progress. | Yogesh Kumar Rohit Kumar Pankaj Raizada Aftab Aslam Parwaz Khan Quyet Van Le Pardeep Singh Van-Huy Nguyen | 2021 | Journal of Materials Science & Technology2021，，28： | 1 |
| 10 | Endoscopic management of intraventricular neurocysticercosis显示文摘 | Rohit Kumar Goel Faiz Uddin Ahmad Ananth Kesav Vellimana Ashish Suri P. Sarat Chandra Rajinder Kumar Bhawani Shankar Sharma Ashok Kumar Mahapatra | 2007 | Journal of Clinical Neuroscience2007，，： | 1 |
| 11 | Urinary Bladder Paraganglioma—A Case Series with Proposed Treating Algorithm Based on Our Experience and Review of Literature显示文摘 | Harvinder S. Pahwa Awanish Kumar Rohit Srivastava Sanjeev Misra Madhu Mati Goel | 2013 | Indian Journal of Surgical Oncology2013，，： | 1 |
| 12 | A prospective study of in-hospital mortality and discharge outcome in spontaneous intracerebral hemorrhage显示文摘 | Rohit Bhatia Hariom Singh Shaily Singh Madakasira Padma Kameshwar Prasad Manjari Tripathi Guresh Kumar Mamta Singh | 2013 | Neurology India2013，，3： | 1 |
| 13 | Advances in treatment and prevention of hepatitis B显示文摘Chronic hepatitis B(CHB)continues to contribute to worldwide morbidity and mortality significantly.Scientists,clinicians,pharmaceutical companies,and health organizations have dedicated substantial Intellectual and monetary resources to finding a cure,increasing immunization rates,and reducing the global burden of CHB.National and international health-related organizations including the center for disease control,the national institute of health,the American Association for the study of liver disease(AASLD),The European association for the study of the Liver(EASL),The Asia Pacific association for the study of the Liver(APASL)and the world health organization release periodic recommendations for disease prevention and treatment.Our review of the most recent guidelines by EASL,AASLD,APASL,and Taiwan Association for the Study of the Liver revealed that an overwhelming majority of cited studies were published before 2018.We reviewed Hepatitis B-related literature published 2018 onwards to identify recent developments and current barriers that will likely direct future efforts towards eradicating hepatitis B.The breakthrough in our understanding of the hepatitis B virus life cycle and resulting drug development is encouraging with significant room for further progress.Data from high-risk populations,most vulnerable to the devastating effects of hepatitis B infection and reactivation remain sparse.Utilization of systems approach,optimization of experimental models,identification and validation of next-generation biomarkers,and precise modulation of the human immune response will be critical for future innovation.Within the foreseeable future,new treatments will likely complement conventional therapies rather than replace them.Most Importantly,pragmatic management of CHB related population health challenges must be prioritized to produce real-world results. | Niraj James Shah Mark M Aloysius Neil Rohit Sharma Kumar Pallav | 2021 | World Journal of Gastrointestinal Pharmacology and Therapeutics2021，12，4： | 1 |
| 14 | Microsomal epoxide hydrolase (EPHX1), slow (exon 3, 113His) and fast (exon 4, 139Arg) alleles confer susceptibility to squamous cell esophageal cancer显示文摘 | Meenu Jain Anup Raj Tilak Rohit Upadhyay Ashwani Kumar Balraj Mittal | 2008 | Toxicology and Applied Pharmacology2008，，2： | 1 |
| 15 | Functional polymorphisms of cyclooxygenase-2 (COX-2) gene and risk for esophageal squmaous cell carcinoma显示文摘 | Rohit Upadhyay Meenu Jain Shaleen Kumar Uday Chand Ghoshal Balraj Mittal | 2009 | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis2009，，1： | 1 |
| 16 | Vicarious liver visualization in solitary functioning kidney with technetium -99m ethy|enedicysteine renal scintigraphy显示文摘 | Jain Tarun Kumar Phulsunga Rohit Kumar Gupta Nitin | 2015 | Indi- an J Nucl Med2015，30，3： | 1 |
| 17 | Quantifying microstructural changes in retinitis pigmentosa using spectral domain – optical coherence tomography显示文摘Background:Most patients of established retinitis pigmentosa(RP)have subnormal peripheral vision and heavily rely on central vision for their daily activities.Central visual acuity is dependent on photoreceptor survival at the macula.Identification of structural changes that precede visual loss is essential.The aim of this study was to correlate the Spectral Domain-Optical Coherence Tomography(SD-OCT)characteristics with visual acuity in patients with typical RP.Methods:This was a retrospective,observational case series of 224 eyes of 113 RP patients conducted a tertiary eye care center.SD-OCT imaging was done for all eyes.Central retinal thickness(CRT),photoreceptor outer segment length(PROS),foveal outer segment pigment epithelial thickness(FOSPET)and ellipsoid zone(EZ)extent were measured.A new variable,FOSPET-PROS ratio(FPR),obtained by dividing FOSPET by PROS is defined and correlated to corrected distance visual acuity(CDVA)in logMAR using linear regression.Results:Out of 113 patients,71 were males and 42 females.Mean age of the patients was 35.4±15.1 years.Mean CDVA was 0.33±0.25 logMAR with no difference between the genders.Mean CRT(218.74±83.5μm)and FPR(1.63±0.22)significantly correlated to CDVA with a correlation coefficient of r=−0.139(p=0.048)and r=0.842(p=0.0001),respectively.FOSPET(mean=71.15±13.8μm)and PROS(mean=44.85±12.5μm)did not show a significant correlation to CDVA,independent of FPR.Conclusions:Retinal microstructural changes on SD-OCT,especially the FPR,can be used as a surrogate marker to monitor disease progression in the central retina in degenerative diseases like RP. | B.Poornachandra Aruj K.Khurana Preethi Sridharan Priyansha Chatterjee Chaitra Jayadev Naresh Kumar Yadav Rohit Shetty | 2019 | Eye and Vision2019，6，1： | 1 |
| 18 | Combined radial and median nerve injury in diaphysea fracture of humerus: a case report显示文摘 | Rajesh Rohilla Rohit Singla Narender Kumar Magu Roop Singh Ashish Devgun Reetadyuti Mukhopadhyay Paritosh Gogna | 2013 | Chinese Journal of Traumatology2013，16，6： | 1 |
| 19 | Miliary nodules due to secondary pulmonary hemosiderosis in rheumatic heart disease显示文摘Pulmonary hemosiderosis is defined as the clinical and functional consequence of iron overload of the lungs,which usually occurs due to recurrent intra-alveolar bleeding.It can manifest as miliary mottling and should be entertained in the differential diagnosis of patients presenting with miliary nodules on chest radiography,especially those with mitral stenosis.The management of secondary pulmonary hemosiderosis secondary to valvular heart disease includes valvuloplasty and/or valve replacement.The radiological opacities may disappear with successful treatment of the underlying valvular disease in many patients.However,they may persist with no physiological impairment to the patient.Here,we present a 32-year-old man with mitral stenosis who presented with fever and miliary shadows on chest radiography,which was ultimately diagnosed as secondary pulmonary hemosiderosis. | Gyanendra Agrawal Ritesh Agarwal Manoj Kumar Rohit Venkat Mahesh Rakesh Kumar Vasishta | 2011 | World Journal of Radiology2011，3，2： | 1 |
| 20 | Fractionation of coal through organo-separative refining for enhancing its potential for the CO2-gasification显示文摘Coal gasification has already been extensively studied earlier under varying conditions of steam,CO2,O2,inert conditions.Belbaid coal and its e,N and NMP-DETA SCC products recovered through organo-refining under milder ambient pressure conditions were subjected to CO2-gasification in a fixed bed reactor under varying conditions.CO2 being an inert gas becomes the most challenging to be utilized during the gasification process.The SCCs showed better CO2-gasification reactivity than the raw Belbaid coal at 900°C.The use of the catalyst K2CO3 tremendously increased the gasification reactivity for both raw coal and the SCCs.The use of sugarcane bagasse for CO2-gasification along with raw coal as well as with residual coal was also studied.Gasification under CO2 atmosphere conditions was used to structurally understand the coals as the coal structure gets loosened after extraction. | Heena Dhawan Rohit Kumar Sreedevi Upadhyayula K.K.Pant D.K.Sharma | 2020 | International Journal of Coal Science & Technology2020，7，3： | 1 |
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