|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Essential role of monocytes and macrophages in the progression of acute pancreatitis显示文摘Acute pancreatitis(AP) is an inflammatory condition of the pancreas caused by an imbalance in factors involved in maintaining cellular homeostasis.Earliest events in AP occur within acinar cells accompanied by other principal contributors to the inflammatory response i.e.the endothelial cells,immunocytes(granulocytes,monocytes/macrophages,lymphocytes) and neutrophils.Monocytes/macrophages are important inflammatory mediators,involved in the pathophysiology of AP,known to reside in the peritoneal cavity(in the vicinity of the pancreas) and in peripancreatic tissue.Recent studies suggested that impaired clearance of injured acini by macrophages is associated with an altered cytokine reaction which may constitute a basis for progression of AP.This review focuses on the role of monocytes/macrophages in progression of AP and discusses f indings on the inflammatory process involved. | Pratima Shrivastava Madhav Bhatia | 2010 | World Journal of Gastroenterology2010，16，32： | 33 |
| 2 | Magnetic resonance imaging staging of nasopharyngeal carcinoma in the head and neck显示文摘Magnetic resonance imaging (MRI) is the modality of choice for staging nasopharyngeal carcinoma in the head and neck. This article will review the patterns of primary and nodal spread on MRI with reference to the latest 7th edition of the International Union Against Cancer/American Joint Committee on Cancer staging system. | Ann Dorothy King Kunwar Suryaveer Singh Bhatia | 2010 | World Journal of Radiology2010，2，5： | 25 |
| 3 | Efficacy of mosapride citrate with polyethylene glycol solution for colonoscopy preparation显示文摘AIM:To evaluate the efficacy and safety of adjunctive mosapride citrate for bowel preparation before colonoscopy. METHODS:We conducted a randomized,double-blind, placebo-controlled study with mosapride in addition to polyethylene glycol(PEG)-electrolyte solution.Of 250 patients undergoing colonoscopy,124 were randomized to receive 2 L PEG plus 15 mg of mosapride citrate (mosapride group),and 126 received 2 L PEG plus placebo(placebo group).Patients completed a questionnaire reporting the acceptability and tolerability of the bowel preparation process.The efficacy of bowel preparation was assessed by colonoscopists using a 5-point scale based on Aronchick's criteria.The primary end point was optimal bowel preparation rates(scores of excellent/good/fair vs poor/inadequate). RESULTS:A total of 249 patients were included in the analysis.In the mosapride group,optimal bowel preparation rates were significantly higher in the left colon compared with the placebo group(78.2%vs 65.6%,P<0.05),but not in the right colon(76.5%vs 66.4%,P=0.08).After excluding patients with severe constipation,there was a significant difference in bowel preparation in both the left and right colon(82.4%vs 66.7%,80.8%vs 67.5%,P<0.05,P<0.01).The incidence of adverse events was similar in both groups. Among the subgroup who had previous colonoscopy experience,a significantly higher number of patients in the mosapride group felt that the current preparation was easier compared with patients in the placebo group(34/72 patients vs 24/74 patients,P<0.05). CONCLUSION:Mosapride citrate may be an effective and safe adjunct to PEG-electrolyte solution that leads to improved quality of bowel preparation,especially in patients without severe constipation. | Masahiro Tajika Yasumasa Niwa Vikram Bhatia Hiroki Kawai Shinya Kondo Akira Sawaki Nobumasa Mizuno Kazuo Hara Susumu Hijioka Kazuya Matsumoto Yuji Kobayashi Akira Saeki Asana Akabane Koji Komori Kenji Yamao | 2012 | World Journal of Gastroenterology2012，18，20： | 21 |
| 4 | Bone mineral density and disorders of mineral metabolism in chronic liver disease显示文摘AIM:To estimate the prevalence and identify the risk factors for metabolic bone disease in patients with cirrhosis.METHODS:The study was performed on 72 Indian patients with cirrhosis(63 male, 9 female;aged < 50 years).Etiology of cirrhosis was alcoholism(n = 37), hepatitis B(n = 25) and hepatitis C(n = 10).Twenty-three patients belonged to Child class A, while 39 were in class B and 10 in class C.Secondary causes for metabolic bone disease and osteoporosis were ruled out.Sunlight exposure, physical activity and dietary constituents were calculated.Complete metabolic profiles were derived, and bone mineral density(BMD) was measured using dual energy X ray absorptiometry.Low BMD was defined as a Z score below-2.RESULTS:Low BMD was found in 68% of patients.Lumbar spine was the most frequently and severely affected site.Risk factors for low BMD included low physical activity, decreased sunlight exposure, and low lean body mass.Calcium intake was adequate, with unfavorable calcium:protein ratio and calcium:phosphorus ratio.Vitamin D deficiency was highly prevalent(92%).There was a high incidence of hypogonadism(41%).Serum estradiol level was elevated significantly in patients with normal BMD.Insulin-like growth factor(IGF) 1 and IGF binding protein 3 levels were below the age-related normal range in both groups.IGF-1 was signiflcantly lower in patients with low BMD.Serum osteocalcin level was low(68%) and urinary deoxypyridinoline to creatinine ratio was high(79%), which demonstrated low bone formation with high resorption.CONCLUSION:Patients with cirrhosis have low BMD.Contributory factors are reduced physical activity, low lean body mass, vitamin D def iciency and hypogonadism and low IGF-1 level. | Joe George Hosahithlu K Ganesh Shrikrishna Acharya Tushar R Bandgar Vyankatesh Shivane Anjana Karvat Shobna J Bhatia Samir Shah Padmavathy S Menon Nalini Shah | 2009 | World Journal of Gastroenterology2009，15，28： | 15 |
| 5 | Strategies to prevent necrotising enterocolitis显示文摘 | Jatinder Bhatia | 2010 | Chinese Medical Journal2010，，20： | 11 |
| 6 | Performance of an activated carbon made from waste palm shell in simultaneous adsorption of SO_x and NO_x of flue gas at low temperature显示文摘This study examined the individual and simultaneous adsorption of SOx (SO2) and NOx (NO-NO2) on activated carbon prepared from waste palm shell. The adsorption process was examined in a fixed bed reactor at low temperatures (100―300℃). For individual adsorption without any catalytic activation, SOx showed good adsorption whereas NOx was very much poor. In the simultaneous adsorption of SOx and NOx, SOx showed greater adsorption affinity than NOx. For palm shell activated carbon (PSAC) impregnated with metal catalyst (Ni and Ce) the concentration adsorbed profile showed that the amount of SOx adsorbed decreased regularly, while the amount of the adsorbed NOx increased irregularly. The properties of the pure and impregnated PSAC were analyzed by BET, SEM and EDX. These investiga-tions indicated that PSAC impregnated with metal catalyst is the determining factor in the adsorption of SOx and NOx simultaneously. | S. SUMATHI S. BHATIA K.T. LEE A. R. MOHAMED | 2009 | Science China(Technological Sciences)2009，52，1： | 11 |
| 7 | Gut microbiome in acute pancreatitis:A review based on current literature显示文摘The gut microbiome is a complex microbial community,recognized for its potential role in physiology,health,and disease.The available evidence supports the role of gut dysbiosis in pancreatic disorders,including acute pancreatitis(AP).In AP,the presence of gut barrier damage resulting in increased mucosal permeability may lead to translocation of intestinal bacteria,necrosis of pancreatic and peripancreatic tissue,and infection,often accompanied by multiple organ dysfunction syndrome.Preserving gut microbial homeostasis may reduce the systemic effects of AP.A growing body of evidence suggests the possible involvement of the gut microbiome in various pancreatic diseases,including AP.This review discusses the possible role of the gut microbiome in AP.It highlights AP treatment and supplementation with prebiotics,synbiotics,and probiotics to maintain gastrointestinal microbial balance and effectively reduce hospitalization,morbidity and mortality in an early phase.It also addresses novel therapeutic areas in the gut microbiome,personalized treatment,and provides a roadmap of human microbial contributions to AP that have potential clinical benefit. | Bharati Kadamb Patel Kadamb H Patel Madhav Bhatia Shridhar Ganpati Iyer Krishnakumar Madhavan Shabbir M Moochhala | 2021 | World Journal of Gastroenterology2021，27，30： | 10 |
| 8 | Automatic Carrier Landing Control for Unmanned Aerial Vehicles Based on Preview Control显示文摘For carrier-based unmanned aerial vehicles(UAVs),one of the important problems is the design of an automatic carrier landing system(ACLS)that would enable the UAVs to accomplish autolanding on the aircraft carrier.However,due to the movements of the flight deck with six degree-of-freedom,the autolanding becomes sophisticated.To solve this problem,an accurate and effective ACLS is developed,which is composed of an optimal preview control based flight control system and a Kalman filter based deck motion predictor.The preview control fuses the future information of the reference glide slope to improve landing precision.The reference glide slope is normally a straight line.However,the deck motion will change the position of the ideal landing point,and tracking the ideal straight glide slope may cause landing failure.Therefore,the predictive deck motion information from the deck motion predictor is used to correct the reference glide slope,which decreases the dispersion around the desired landing point.Finally,simulations are carried out to verify the performance of the designed ACLS based on a nonlinear UAV model. | Zhen Ziyang Ma Kun Bhatia Ajeet Kumar | 2017 | Transactions of Nanjing University of Aeronautics and Astronautics2017，34，4： | 8 |
| 9 | Can mosapride citrate reduce the volume of lavage solution for colonoscopy preparation?显示文摘AIM:To evaluate the possibility of reducing the volume of polyethylene glycol(PEG)-electrolyte solution using adjunctive mosapride citrate for colonoscopy preparation. METHODS:This was a single-center,prospective, randomized,investigator-blinded,non-inferiority study involving 252 patients of both sexes,aged from 20 to 80 years,scheduled for screening or diagnostic colonoscopy in our department.A total of 126 patients was randomized to receive 1.5 L PEG-electrolyte solution plus 15 mg of mosapride(1.5 L group),and 126 received 2 L PEG-electrolyte solution plus 15 mg of mosapride(2 L group).Patients completed a questionnaire on the acceptability and tolerability of the bowel preparation process.The efficacy of bowel preparation was assessed using a 5-point scale based on the Aronchick scale.The primary end point was adequate bowel preparation rates(score of excellent/good/fair) vs(poor/inadequate).Acceptability and tolerability,as well as disease detection,were secondary end points. RESULTS:A total of 244 patients was included in the analysis.There were no significant differences between the 2 L and 1.5 L groups in age,sex,body mass index, number of previous colonoscopies,and the preparation method used previously.The adequate bowel preparation rates were 88.5%in the 2 L group and 82.8%in the 1.5 L group[95%lower confidence limit(LCL)for the difference=-14.5%,non-inferiority P=0.019]in the right colon.In the left colon,the adequate bowel preparation rates were 89.3%in the 2 L group and 81.1%in the 1.5 L group(95%LCL=-17.0%,non-inferiority P=0.066).Compliance,defined as complete (100%)intake of the PEG solution,was significantly higher in the 1.5 L group than in the 2 L group(96.8% vs 85.7%,P=0.002).The proportion of abdominal distension(none/mild/moderate/severe)was significantly lower in the 1.5 L group than in the 2 L group (36/65/22/3 vs 58/48/18/2,P=0.040).Within the subgroup who had undergone colonoscopy previously, a significantly higher number of patients in the 1.5 L group than in the 2 L group felt that the current preparation was easier than the previous one(54.1%vs 28.0%,P=0.001).The disease detection rate was not significantly different between the two groups. CONCLUSION:Although the 1.5 L group had better acceptability and tolerability,15 mg of mosapride may be insufficient to compensate for a 0.5-L reduction of PEG solution. | Masahiro Tajika Yasumasa Niwa Vikram Bhatia Shinya Kondo Tsutomu Tanaka Nobumasa Mizuno Kazuo Hara Susumu Hijioka Hiroshi Imaoka Koji Komori Kenji Yamao | 2013 | World Journal of Gastroenterology2013，19，5： | 8 |
| 10 | Prospective clinical study of endoscopic ultrasound-guided choledochoduodenostomy with direct metallic stent placement using a forward-viewing echoendoscope显示文摘 | K. Hara K. Yamao S. Hijioka N. Mizuno H. Imaoka M. Tajika S. Kondo T. Tanaka S. Haba O. Takeshi Y. Nagashio T. Obayashi A. Shinagawa V. Bhatia Y. Shimizu H. Goto Y. Niwa | 2013 | Endoscopy2013，，05： | 6 |
| 11 | Percutaneous embolization of varicocele: technique, indications, relative contraindications, and complications显示文摘为精索静脉曲张的处理有几种选择,也包括外科的修理由开或 microsurgical 途径, laparoscopy,或通过内部精子的静脉的经皮的 embolization。精索静脉曲张处理的最终的目标依靠排干睾丸的扩大静脉的吸藏。经皮的 embolization 提供快速的恢复和罐头成功地在约 90% 尝试被完成。然而,这种技术要求 interventional 放射线学的专家知识并且有 pampiniform 的潜在的严肃的复杂并发症,包括的脉管的穿孔,卷迁居,和血栓丛。这评论讨论与精索静脉曲张的经皮的 embolization 联系的普通指示,相对禁止徵候,技术细节,和风险。 | Joshua Halpern Sameer Mittal Keith Pereira Shivank Bhatia Ranjith Ramasamy | 2016 | Asian Journal of Andrology2016，18，2： | 5 |
| 12 | Predictors of fifty days in-hospital mortality in decompensated cirrhosis patients with spontaneous bacterial peritonitis显示文摘AIM: To determine the predictors of 50 d in-hospital mortality in decompensated cirrhosis patients with spontaneous bacterial peritonitis(SBP).METHODS: Two hundred and eighteen patients admitted to an intensive care unit in a tertiary care hospital between June 2013 and June 2014 with the diagnosis of SBP(during hospitalization) and cirrhosis were retrospectively analysed. SBP was diagnosed by abdominal paracentesis in the presence of polymorphonuclear cell count ≥ 250 cells/mm3 in the peritoneal fluid. Student's t test, multivariate logistic regression, cox proportional hazard ratio(HR), receiver operating characteristics(ROC) curves and Kaplan-Meier survival analysis were utilized for statistical analysis. Predictive abilities of several variables identified by multivariate analysis were compared using the area under ROC curve. P < 0.05 were considered statistical significant. RESULTS: The 50 d in-hospital mortality rate attributable to SBP is 43.11%(n = 94). Median survival duration for those who died was 9 d. In univariate analysis acute kidney injury(AKI), hepatic encephalopathy, septic shock, serum bilirubin, international normalized ratio, aspartate transaminase, and model for end-stage liver disease- sodium(MELD-Na) were significantly associated with in- hospital mortality in patients with SBP(P ≤ 0.001). Multivariate coxproportional regression analysis showed AKI(HR = 2.16, 95%CI: 1.36-3.42, P = 0.001) septic shock(HR = 1.73, 95%CI: 1.05-2.83, P = 0.029) MELD-Na(HR = 1.06, 95%CI: 1.02-1.09, P ≤ 0.001) was significantly associated with 50 d in-hospital mortality. The prognostic accuracy for AKI, MELD-Na and septic shock was 77%, 74% and 71% respectively associated with 50 d inhospital mortality in SBP patients.CONCLUSION: AKI, MELD-Na and septic shock were predictors of 50 d in-hospital mortality in decompensated cirrhosis patients with SBP. | Chinmaya Kumar Bal Ripu Daman Vikram Bhatia | 2016 | World Journal of Hepatology2016，8，12： | 5 |
| 13 | Relationship between HER-2 overexpression and brain metastasis in esophageal cancer patients显示文摘AIM:To study if HER-2 overexpression by locally advanced esophageal cancers increase the chance of brain metastasis following esophagectomy.METHODS:We retrospectively reviewed the medical records of esophageal cancer patients who underwent esophagectomy at University of Iowa Hospitals and Clinics between 2000 and 2010.Data analyzed consisted of demographic and clinical variables.The brain metastasis tissue was assayed for HER-2 overexpression utilizing the FDA approved DAKO Hercept Test.RESULTS:One hundred and forty two patients were reviewed.Median age was 64 years(36-86 years).Eighty eight patients(62%) received neoadjuvant chemoradiotherapy.Pathological complete and partial responses were achieved in 17(19%) and 71(81%) patients.Cancer relapsed in 43/142(30%) patients.The brain was the first site of relapse in 9/43 patients(21%,95% CI:10%-36%).HER-2 immunohistochemistry testing of the brain metastasis tissue showed that 5/9(56%) cases overexpressed HER-2(3+ staining).CONCLUSION:HER-2 overexpression might be associated with increased risk of brain metastasis in esophageal cancer patients following esophagectomy.Further studies will be required to validate this observation. | Taher Abu Hejleh Barry R DeYoung Eric Engelman Jeremy M Deutsch Bridget Zimmerman Thorvardur R Halfdanarson Daniel J Berg Kalpaj R Parekh William R Lynch Mark D Iannettoni Sudershan Bhatia Gerald Clamon | 2012 | World Journal of Gastrointestinal Oncology2012，4，5： | 5 |
| 14 | Trace element characteristics of graywackes and tectonic setting discrimination of sedimentary basins显示文摘 | Mukul R. Bhatia Keith A. W. Crook | 1986 | Contributions to Mineralogy and Petrology1986，，2： | 5 |
| 15 | A Global Perspective on Irritable Bowel Syndrome: A Consensus Statement of the World Gastroenterology Organisation Summit Task Force on Irritable Bowel Syndrome显示文摘 | Eamonn M. M. Quigley Hussein Abdel-Hamid Giovanni Barbara Shobna J. Bhatia Guy Boeckxstaens Roberto De Giorgio Michel Delvaux Douglas A. Drossman Amy E. Foxx-Orenstein Francisco Guarner Kok-Ann Gwee Lucinda A. Harris A. Pali S. Hungin Richard H. Hunt John | 2012 | Journal of Clinical Gastroenterology2012，，5： | 4 |
| 16 | Prognostic value of K - ras mutation status and subtypes in endoscopic ultrasound-guided fine-needle aspiration specimens from patients with unresectable pancreatic cancer显示文摘 | Takeshi Ogura Kenji Yamao Kazuo Hara Nobumasa Mizuno Susumu Hijioka Hiroshi Imaoka Akira Sawaki Yasumasa Niwa Masahiro Tajika Shinya Kondo Tsutomu Tanaka Yasuhiro Shimizu Vikram Bhatia Kazuhide Higuchi Waki Hosoda Yasushi Yatabe | 2013 | Journal of Gastroenterology2013，，5： | 4 |
| 17 | Risk of ileal pouch neoplasms in patients with familial adenomatous polyposis显示文摘Restorative proctocolectomy is the most common surgical option for patients with familial adenomatous polyposis(FAP). However,adenomas may develop in the ileal pouch mucosa over time,and even carcinoma in the pouch has been reported. We therefore reviewed the prevalence,nature,and treatment of adenomas and carcinoma that develop after proctocolectomy in the ileal pouch mucosa in patients with FAP. In 25 reports that were reviewed,the incidence of adenomas in the ileal pouch varied from 6.7% to 73.9%. Several potential factors that favor the development of pouch polyposis have been investigated,but many remain controversial. Nevertheless,it seems certain that the age of the pouch is important. The risk appears to be 7%to 16% after 5 years,35% to 42% after 10 years,and75% after 15 years. On the other hand,only 21 cases of ileal pouch carcinoma have been recorded in the literature to date. The diagnosis of pouch carcinoma was made between 3 to 20 years(median,10 years) after pouch construction. Although the risk of malignant transformation in ileal pouches is probably low,it is not negligible,and the long-term risk cannot presently be well quantified. Regular endoscopic surveillance,especially using chromoendoscopy,is recommended. | Masahiro Tajika Yasumasa Niwa Vikram Bhatia Tsutomu Tanaka Makoto Ishihara Kenji Yamao | 2013 | World Journal of Gastroenterology2013，19，40： | 4 |
| 18 | Abnormalities of uterine cervix in women with inflammatory bowel disease显示文摘AIM: To evaluate the prevalence of abnormalities of the uterine cervix in women with inflammatory bowel disease (IBD) when compared to healthy controls. METHODS: One hundred and sixteen patients with IBD [64 with Crohn’s disease (CD) and 52 with ulcerative colitis (UC)] were matched to 116 healthy controls by age (+/- 2 years) at the time of most recent papanicolaou (Pap) smear. Data collected consisted of age, race, marital status, number of pregnancies, abortions/miscarriages, duration and severity of IBD, Pap smear results within five years of enrollment, and treatment with immunosuppressive drugs. Pap smear results were categorized as normal or abnormal including atypical squamous cells of undetermined significance (ASCUS), low-grade squamous intraepithelial lesion (LGSIL), and high-grade squamous intraepithelial lesion (HGSIL). RESULTS: The median age at the time of Pap smear was 46 (range: 17-74) years for the IBD group and matched controls (range: 19-72 years). There were more Caucasian subjects than other ethnicities in the IBD patient group (P = 0.025), as well as fewer abortions (P = 0.008), but there was no significant difference regarding marital status. Eighteen percent of IBD patients had abnormal Pap smears compared to 5% of controls (P = 0.004). Subgroup analysis of the IBD patients revealed no significant differences between CD and UC patients in age, ethnicity, marital status, number of abortions, disease severity, family history of IBD, or disease duration. No significant difference was observedin the number of abnormal Pap smears or the use of immunosuppressive medications between CD and UC patients (P = 0.793). No definitive observation could be made regarding HPV status, as this was not routinely investigated during the timeframe of our study. CONCLUSION: Diagnosis of IBD in women is related to an increased risk of abnormal Pap smear, while type of IBD and exposure to immunosuppressive medications are not. This has significant implications for women with IBD in that Pap smear screening protocols should be conscientiously followed, with appropriate investigation of abnormal results. | Jyoti Bhatia Jason Bratcher Burton Korelitz Katherine Vakher Shlomo Mannor Maria Shevchuk Gworgia Panagopoulos Adam Ofer Ecaterina Tamas Panayota Kotsali Oana Vele | 2006 | World Journal of Gastroenterology2006，12，38： | 3 |
| 19 | Electrophysiological neuromonitoring of the laryngeal nerves in thyroid and parathyroid surgery: A review显示文摘Recurrent laryngeal nerve(RLN) injury is one of the most common complications of thyroid surgery. Injury to the external branch of the superior laryngeal nerve is less obvious and affects the voice variably; however, it can be of great significance to professional voice users. Recent literature has led to an increase in the use of neuromonitoring as an adjunct to visual nerve identification during thyroid surgery. In our review of the literature, we discuss the application, efficacy and safety of neuromonitoring in thyroid surgery. Although intraoperative neuromonitoring(IONM) contributes to the prevention of laryngeal nerves injury, there was no significant difference in the incidence of RLN injury in thyroid surgery when IONM was used compared with visual identification alone. IONM use is recommended in high risk patients; however, there are no clear identification criteria for what constitutes 'high risk'. There is no clear evidence that IONM decreases the risk of laryngeal nerve injury in thyroid surgery. However, continuous IONM provides a promising tool that can prevent imminent nerve traction injury by detecting decreased amplitude combined with increased latency. | Ahmed Deniwar Parisha Bhatia Emad Kandil | 2015 | World Journal of Experimental Medicine2015，5，2： | 3 |
| 20 | Can EUS-guided FNA distinguish between gallbladder cancer and xanthogranulomatous cholecystitis?显示文摘 | Susumu Hijioka Mohamed A. Mekky Vikram Bhatia Akira Sawaki Nobumasa Mizuno Kazuo Hara Waki Hosoda Yasuhiro Shimizu Kiichi Tamada Yasumasa Niwa Kenji Yamao | 2010 | Gastrointestinal Endoscopy2010，，3： | 3 |
您所在的机构暂未开通此部分的功能，请联系管理员