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2043篇 您的检索式:作者名="Suri"
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1Unusual disposition of lateral circumflex femoral artery: Anatomical description and clinical implications显示文摘The anatomical knowledge of arterial variations of lower limb is of utmost significance for the present day surgeons and interventional radiologists for minimizing complications during vascular reconstructive procedures, catheterization procedures and surgical intervention for embolism. Lateral Circumflex Femoral Artery(LCFA) isan important branch of Profunda Femoris artery and precise knowledge of its variations can be of great relevance during surgical and radiological procedures in femoral region. The present study reports a unique case of anomalous route taken by LCFA posterior to femoral nerve associated with a prominent muscular branch from Femoral artery mimicking the course of LCFA. Documentation of such variations is highly significant. It may serve as guideline for surgeons in reducing the incidence of postoperative complications where LCFA is used as a long vascular pedicle in anterolateral perforator thigh flap and in breast reconstruction after mastectomy. Ignorance of such variations can lead to fatal intraoperative haemorrhage and incapacitating sensory and motor deficit due to injury to femoral nerve branches which are closely related to these vessels.Shivi Goel Jyoti Arora Vandana Mehta Mona Sharma Rajesh Kumar Suri Gayatri Rath 2015World Journal of Clinical Cases2015,3,1:11
2Role of over the scope clips in the management of iatrogenic gastrointestinal perforations显示文摘Advances in endoscopic and surgical techniques have increased the frequency and complexity of these procedures and associated complications such as gastrointestinal perforation. With the advancements in the field of gastroenterology, the promising use of an over the scope clips(OTSC) has fulfilled the unmet need for a reliable endoscopic devise in approximation of gastrointestinal perforation. This novel approach has raised the level of confidence in endoscopist in dealing with this serious complication during endoscopy. Here we have shared our experience with OTSC to evaluate its efficacy and safety in managing iatrogenic gastrointestinal perforations during endoscopy.Kinesh Changela Muhhamad A Virk Niravkumar Patel Sushil Duddempudi Mahesh Krishnaiah Sury Anand 2014World Journal of Gastroenterology2014,20,32:7
3Targeting cancer testis antigens for biomarkers and immunotherapy in colorectal cancer: Current status and challenges显示文摘Colorectal cancer ranks third among the estimatedcancer cases and cancer related mortalities in United States in 2014. Early detection and efficient therapy remains a significant clinical challenge for this disease. Therefore, there is a need to identify novel tumor asso-ciated molecules to target for biomarker development and immunotherapy. In this regard, cancer testis antigens have emerged as a potential targets for developing novel clinical biomarkers and immunotherapy for various malignancies. These germ cell specific proteins exhibit aberrant expression in cancer cells and contribute in tumorigenesis. Owing to their unique expression profile and immunogenicity in cancer patients, cancer testis antigens are clinically referred as the most promising tumor associated antigens. Several cancer testis antigens have been studied in colorectal cancer but none of them could be used in clinical practice. This review is an attempt to address the promising cancer testis antigens in colorectal cancer and their possible clinical implications as biomarkers and immunotherapeutic targets with particular focus on challenges and future interventions.Anil Suri Nirmala Jagadish Shikha Saini Namita Gupta 2015World Journal of Gastrointestinal Oncology2015,7,12:4
4Importance of reporting segmental bowel preparation scores during colonoscopy in clinical practice显示文摘AIM: To evaluate the impact of reporting bowel preparation using Boston Bowel Preparation Scale(BBPS) in clinical practice.METHODS: The study was a prospective observational cohort study which enrolled subjects reporting for screening colonoscopy. All subjects received a gallon of polyethylene glycol as bowel preparation regimen. After colonoscopy the endoscopists determined quality of bowel preparation using BBPS. Segmental scores were combined to calculate composite BBPS. Site and size of the polyps detected was recorded. Pathology reports were reviewed to determine advanced adenoma detection rates(AADR). Segmental AADR's were calculated and categorized based on the segmental BBPS to determine the differential impact of bowel prep on AADR. RESULTS: Three hundred and sixty subjects were enrolled in the study with a mean age of 59.2 years, 36.3% males and 63.8% females. Four subjects with incomplete colonoscopy due BBPS of 0 in any segment were excluded. Based on composite BBPS subjects were divided into 3 groups; Group-0(poor bowel prep, BBPS 0-3) n = 26(7.3%), Group-1(Suboptimal bowel prep, BBPS 4-6) n = 121(34%) and Group-2(Adequate bowel prep, BBPS 7-9) n = 209(58.7%). AADR showed a linear trend through Group-1 to 3; with an AADR of 3.8%, 14.8% and 16.7% respectively. Also seen was a linear increasing trend in segmental AADR with improvement in segmental BBPS. There was statistical significant difference between AADR among Group 0 and 2(3.8% vs 16.7%, P < 0.05), Group 1 and 2(14.8% vs 16.7%, P < 0.05) and Group 0 and 1(3.8% vs 14.8%, P < 0.05). χ2 method was used to compute P value for determining statistical significance.CONCLUSION: Segmental AADRs correlate with segmental BBPS. It is thus valuable to report segmental BBPS in colonoscopy reports in clinical practice.Deepanshu Jain Mojdeh Momeni Mahesh Krishnaiah Sury Anand Shashideep Singhal 2015World Journal of Gastroenterology2015,21,13:4
5Genetics on early onset inflammatory bowel disease:An update显示文摘Inflammatory bowel disease(IBD)is more common in adults than in children.Onset of IBD before 17 years of age is referred as pediatric onset IBD and is further categorized as very early onset IBD(VEO-IBD)for children who are diagnosed before 6 years of age,infantile IBD who had the disease before 2 years of age and neonatal onset IBD for children less than 28 days of life.Children presenting with early onset disease may have a monogenic basis.Knowledge and awareness of the clinical manifestations facilitates early evaluation and diagnosis.Next generation sequencing is helpful in making the genetic diagnosis.Treatment of childhood IBD is difficult;targeted therapies and hematopoietic stem cell transplantation form the mainstay.In this review we aim to summarize the genetic defects associated with IBD phenotype.We describe genetic location and functions of various genetic defect associated with VEO-IBD with their key clinical manifestations.We also provide clinical clues to suspect these conditions and approaches to the diagnosis of these disorders and suitable treatment options.Johnson Nameirakpam Rashmi Rikhi Sanjay Singh Rawat Jyoti Sharma Deepti Suri 2020Genes & Diseases2020,7,1:3
6Review of efficacy and safety of laxatives use in geriatrics显示文摘AIM:To study the efficacy and safety of pharmacolo-gical treatment of constipation in geriatrics.METHODS:Pub Med,MEDLINE,google scholar,and Ovid were searched to identify human studies performed on the use of laxatives in elderly with constipation,which were conducted between January1990 and January 2013 using the specified keywords.Controlled studies that enrolled geriatric patients with a diagnosis of constipation and addressed the efficacy and/or the safety of pharmacological treatments were included.Studies were excluded from this review if they were non-controlled trials,case series,or case reports.RESULTS:Out of twenty three studies we initially retrieved in our search,only nine studies met the eligibility criteria of being controlled trials within geriatrics.The laxatives examined in the nine studies were senna,lactulose,sorbital,polyethylene glycol(PEG),lubiprostone,linaclotide,and prucalopride.In those studies,senna combinations had a higher efficacy than sorbitol or lactulose as well as,a very good adverse effect profile.PEG was also shown to be safe and effective in geriatric population.Furthermore,it has been shown that PEG is as safe in geriatrics as in general population.New agents like lubiprostone and prucalopride show promising results but the data about these agents in geriatrics are still limited which warrant further investigation.CONCLUSION:Senna combinations and PEG appear to have a more favorable profile over the other traditionally used laxatives in elderly patients with constipation.Manhal Izzy Anju Malieckal Erin Little Sury Anand 2016World Journal of Gastrointestinal Pharmacology and Therapeutics2016,7,2:3
7Novel anti-diabetic agents in non-alcoholic fatty liver disease: a mini-review显示文摘BACKGROUND:Non-alcoholic fatty liver disease(NAFLD)encompasses a spectrum that ranges from simple steatosis to non-alcoholic steatohepatitis(NASH)and to cirrhosis.The recommended treatment for this disease includes measures that target obesity and insulin resistance.The present review summarizes the role of newer anti-diabetic agents in treatment of NAFLD.DATA SOURCES:PubMed,MEDLINE and Ovid databases were searched to identify human studies between January 1990and January 2013 using specified key words.Original studies that enrolled patients with a diagnosis of NAFLD or NASH and involved use of newer classes of anti-diabetic agents for a duration of at least 3 months were included.RESULTS:Out of the screened articles,four met eligibility criteria and were included in our review.The classes of newer anti-diabetic medications described were dipeptidyl peptidase IV inhibitors and glucagon-like peptide-1 analogues.CONCLUSIONS:Liraglutide and Exenatide showed improvement in transaminases as well as histology in patients with NASH.Sitagliptin showed improvement in transaminases but limited studies are there to access its effect on histology.Further studies are needed to support use of newer anti-diabetic medications in patients with NAFLD.Manhal Olaywi Taruna Bhatia Sury Anand Shashideep Singhal 2013Hepatobiliary & Pancreatic Diseases International2013,12,6:3
8Angiopoietin-2,a natural antagonist for Tie2 that disrupts in vivo angiogenesis 显示文摘Maisonpierre P C Suri C Johes P F 1997Science1997,277,5322:2
9Peroral endoscopic reduction of dilated gastrojejunal anastomosis after bariatric surgery: Techniques and efficacy显示文摘AIM: To investigate the techniques and efficacy of peroral endoscopic reduction of dilated gastrojejunal anastomosis after bariatric surgery.METHODS: An extensive English language literature search was conducted using Pub Med, MEDLINE, Medscape and Google to identify peer-reviewed original and review articles using the keywords 'bariatric endoscopic suturing', 'overstitch bariatric surgery', 'endoscopic anastomotic reduction', 'bariatric surgery', 'gastric bypass', 'obesity', 'weight loss'. We identified articles describing technical feasibility, safety, efficacy, and adverse outcomes of overstitch endoscopic suturing system for transoral outlet reduction in patients with weight regain following Roux-en-Y gastric bypass(RYGB). All studies that contained material applicable to the topic were considered. Retrieved peer-reviewed original and review articles were reviewed by the authors and the data extracted using a standardized collection tool. Data were analyzed using statistical analysis as percentages of the event. RESULTS: Four original published articles which met our search criteria were pooled. The total number cases were fifty-nine with a mean age of 46.75 years(34-63 years). Eight of the patients included in those studies were males(13.6%) and fifty-one were females(86.4%). The mean time elapsed since the primary bypass surgery was 5.75 years. The average pre-endoscopic procedure body mass index(BMI) was 38.68(27.5-48.5). Mean body weight regained post-RYGB surgery was 13.4 kg from their post-RYGB nadir. The average pouch length at the initial upper endoscopy was 5.75 cm(2-14 cm). The pre-intervention anastomotic diameter was averaged at 24.85 mm(8-40 mm). Average procedure time was 74 min(50-164 min). Mean post endoscopic intervention anastomotic diameter was 8 mm(3-15 mm). Weight reduction at 3 to 4 mo post revision noted to be anaverage of 10.1 kg. Average overall post revision BMI was recorded at 37.7. The combined technical and clinical success rate was 94.9%(56/59) among studied participants. CONCLUSION: Endoscopic suturing can be technically feasible, effective and safe for transoral outlet reduction in patients with weight regain following RYGB.Kinesh Changela Emmanuel Ofori Sushil Duddempudi Sury Anand Shashideep Singhal 2016World Journal of Gastrointestinal Endoscopy2016,8,4:2
10Over the Scope Clip: Technique and Expanding Clinical Applications显示文摘Shashideep Singhal Kinesh Changela Haris Papafragkakis Sury Anand Mahesh Krishnaiah Sushil Duddempudi 2013Journal of Clinical Gastroenterology2013,,9:2
11Angiopoietin-2,a natural antagonist for Tie2 that disrupts in vivo angiogenesis显示文摘Maisonpierre PC Suri C Jones PF 0,,:2
12CT features of acute phlegmonous gastritis显示文摘Bimal P. Sood Naveen Kalra S. Suri 2001Clinical Imaging2001,,5:2
13甲醛气涂尿素显示文摘Suri,IK 高俊文 1990化肥工业译丛1990,,3:2
14Angiopoietin-2,a natural antagonistor for Tie2 that distrupts in vivo angiogenesis显示文摘Maisonpierre PC Suri C Jones PF 1997Science1997,277,4:2
15Bacterial extracellular vesicle applications in cancer immunotherapy显示文摘Cancer therapy is undergoing a paradigm shift toward immunotherapy focusing on various approaches to activate the host immune system.As research to identify appropriate immune cells and activate anti-tumor immunity continues to expand,scientists are looking at microbial sources given their inherent ability to elicit an immune response.Bacterial extracellular vesicles(BEVs)are actively studied to control systemic humoral and cellular immune responses instead of using whole microorganisms or other types of extracellular vesicles(EVs).BEVs also provide the opportunity as versatile drug delivery carriers.Unlike mammalian EVs,BEVs have already made it to the clinic with the meningococcal vaccine(Bexsero®).However,there are still many unanswered questions in the use of BEVs,especially for chronic systemically administered immunotherapies.In this review,we address the opportunities and challenges in the use of BEVs for cancer immunotherapy and provide an outlook towards development of BEV products that can ultimately translate to the clinic.Kanika Suri Anisha D’Souza Di Huang Aashray Bhavsar Mansoor Amiji 2023Bioactive Materials2023,,4:2
16Packet classification using tuple space search显示文摘Srinivasan V Suri S Varghese G 1999Proceedings of ACM Sigcomm Communication Review Archive1999,29,4:2
17Organic acids production from lactic acid bacteria:A preservation approach显示文摘The lactic acid bacteria(LAB)are a group of gram-positive bacteria capable of converting carbohydrate substrates into organic acids and producing a wide range of metabolites.Organic acids,including propionic,formic,acetic acid,and lactic acid,create an unfavorable environment for the growth of spoilage and pathogenic microorganisms.Also,they are employed as monomers or starting ingredients for food-based supplements,biomaterials,and biodegradable polymers.Organic acids from LAB have the potential to prevent spoilage and improve food taste that enhances consumer acceptance and appeal.Organic acids can be useful as starting materials in multiple applications,including food,chemical,cosmetic,pharmaceutical,and beverage industries owing to their various functional properties.Additionally,the use of LAB for organic acids production can replace petroleum-based processes due to their ability to utilize inexpensive and renewable feedstocks.This article aims to provide the potential of LAB as a biological catalyst for producing different organic acids.Also,the current review will give a critical snapshot of the strategies to improve microbial organic acid production and potential application of organic acids and discuss new challenges and opportunities for developing novel economically effective and sustainable nutritional sources and techniques.Sneh Punia Bangar Shweta Suri Monica Trif Fatih Ozogul 2022Food Bioscience2022,46,2:2
18Processing of rare earth concentrates显示文摘The paper describes process details for extraction of rare earths from an intermediate grade concentrate ofMadhya Pradesh region in India and a South African slag. The xenotime concentrate obtained from the former place was anintermediate grade (47%) rare earth phosphate containing both monazite and xenotime. The South African slag was alow-grade waste product typically containing only 4% of rare earths. The rare earth resource concentrates have been treatedindividually by different methods such as alkali fusion and alkali leaching to convert them into their mixed oxides. Bothtypes of materials have been processed and greater than 98% solubilization of metal values has been achieved in the inter-mediate grade xenotime and 80% from the South African slag. The residue of xenotime hydroxide has been washed thor-oughly to collect the sodium phosphate, as by-product and the slurry pH have been adjusted to separate rare earths fromthorium effectively. Other impurities such as uranium and iron have been removed by precipitation of rare earths by oxalicacid. It has been possible to recover >95% yttrium along with other rare earth oxides.Pamela Alex R.C. Hubli A.K. Suri 2005Rare Metals2005,24,3:2
19Synthesis of nanocrystalline ZnO powder via sol–gel route for dye-sensitized solar cells显示文摘Seema Rani Poonam Suri P.K. Shishodia R.M. Mehra 2008Solar Energy Materials and Solar Cells2008,,12:2
20基于全基因组测序筛选腰椎管狭窄症易感基因突变位点显示文摘识别腰椎疾病的遗传易感因素有助于了解该病的潜在发病机制和探索新的治疗方法。通过电子病历系统、基因组网络以及格伊辛格卫生系统纳入100,811名参与者,对基因型和电子病历资料进行全基因组关联分析(GWAS),使用有效算法和临床诊断代码将其分为病例组和对照组。病例组包括需医疗干预的腰痛(LBP-HC)、腰骶神经根综合征(LSRS)和腰椎管狭窄症(LSS)。GWAS采用多因素Logistic回归分析,根据年龄、性别、特定区域因素和种族进行累积效应校正,并进行了固定效应反方差加权荟萃分析。全基因组意义上的遗传变异(P<5×10^(-8))可以在UKB的独立样本中进行重复验证。研究数据显示LBP-HC的患病率为48.8%,LSRS的患病率为19.8%,LSS的患病率为7.9%,其中LBP-HC无显著相关易感基因突变;LSRS存在相关易感基因突变位点(rs146153280:C>G,G的比值比OR=1.17,P=2.1×10^(-9)),但未得到重复验证;与LSS相关联的易感突变基因是位于2号染色体上编码GFPT1,NFU1和AAK1基因的位点(rs13427243:G>A,A的比值比OR=1.10,P=4.3×10^(-8)),并可重复验证(OR=1.11,P=5.4×10^(-5))。这是使用电子病历数据对腰椎疾病进行GWAS的第一个荟萃分析。通过本研究确定了与LSRS和LSS关联的两个新的易感基因突变位点,后者可重复验证。Suri P Stanaway IB Zhang Y 梁辰(译) 李水清(校) 2021中国疼痛医学杂志2021,27,7:2
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