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| 1 | Conversion of laparoscopic colorectal resection for cancer: What is the impact on short-term outcomes and survival?显示文摘Laparoscopic resection for colon and rectal cancer is associated with quicker return of bowel function, reduced postoperative morbidity rates and shorter length of hospital stay compared to open surgery, with no differences in long-term survival. Conversion to open surgery is reported in up to 30% of patients enrolled in randomized control trials comparing open and laparoscopic colorectal resection for cancer. In this review, reasons for conversion are anatomical-related factors, disease-related-factors and surgeon-related factors. Body mass index, local tumour extension and co-morbidities are independent predictors of conversion. The current evidence has shown that patients with converted resection for colon cancer have similar outcomes compared to patients undergoing a laparoscopic completed or open resection. The few studies that have assessed the outcomes after conversion of laparoscopic rectal resection reported significantly higher rates of complications and longer length of hospital stay in converted patients compared to laparoscopically treated patients. No definitive conclusions can be drawn when converted and open rectal resections are compared. Early and pre-emptive conversion appears to have more favourable outcomes than reactive conversion; however, further large studies are needed to better define the optimal timing of conversion. With regard to long-term oncologic outcome, overall and disease-free survival in the case of conversion in laparoscopic colorectal cancer surgery seems to be worse than those achieved in patients in whom resection was successfully completed by laparoscopy. Although a worse long-term oncologic outcome has been suggested, it remains difficult to draw a proper conclusion due to the heterogeneity of the long-term outcomes as well as the inclusion of both colon and rectal cancer patients in most of the studies. Therefore, we discuss the currently available evidence of the impact of conversion in laparoscopic resection for colon and rectal cancer on both short-term outcomes and long-term survival. | Marco E Allaix Edgar JB Furnée Massimiliano Mistrangelo Alberto Arezzo Mario Morino | 2016 | World Journal of Gastroenterology2016，22，37： | 11 |
| 2 | Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial显示文摘 | Roger Stupp Monika E Hegi Warren P Mason Martin J van den Bent Martin JB Taphoorn Robert C Janzer Samuel K Ludwin Anouk Allgeier Barbara Fisher Karl Belanger Peter Hau Alba A Brandes Johanna Gijtenbeek Christine Marosi Charles J Vecht Karima Mokhtari Piet | 2009 | Lancet Oncology2009，，5： | 4 |
| 3 | 难治性疼痛和高血压在急性B型主动脉夹层中的重要性:国际急性主动脉夹层登记的意见显示文摘急性B型主动脉夹层患者,可表现出对药物治疗无效的反复、难治性疼痛和(或)难治性高血压,当出现这些症状时有时可作为介入治疗的指征。研究者利用国际急性主动脉夹层登记(international registry of a-cute aortic dissection,IRAD)的资料调查难治性疼痛和(或)难治性高血压对急性B型主动脉夹层患者临床转归的影响。 | 张玲玉 叶鹏 Trimarchi S Eagle KA Nienaber CA Pyeritz RE Jonker FH Suzuki T O'Gara PT Hutchinson SJ Rampoldi V Grassi V Bossone E Muhs BE Evangelista A Tsai TT Froehlich JB Cooper JV Montgomery D Mein-hardt G Myrmel T Upchurch GR Sundt TM Issel-bacher EM | 2010 | 中华高血压杂志2010，18，12： | 4 |
| 4 | 高血压与糖尿病:共同发展与时间轨迹研究显示文摘在人群中2型糖尿病与高血压常合并存在。许多个体糖尿病的发展特点是血浆葡萄糖值的相对快速升高。高血压的发展是否存在相似的现象仍不明确。该研究采用来自墨西哥城糖尿病研究(Mexico city diabetes study,MCDS;一个基于西班牙裔白人的糖尿病人群研究)及Framingham后代研究(Framingham offspring study,FOS;一个基于社区的非西班牙裔白人研究)的7年随访数据,分析未合并或合并糖尿病的患者高血压发展过程中的血压变化模式。 | 赵狄 练桂丽 Tsimihodimos V Gonzalez-Villalpando C Meigs JB Ferrannini E | 2018 | 中华高血压杂志2018，26，1： | 3 |
| 5 | ADA与EASD对2型糖尿病高血糖处理:治疗启动与评定的新共识方案显示文摘在不到一年时间由同一批专家代表ADA和EASD先后起草和发布了两次关于'2型糖尿病高血糖处理的共识声明'同时发表在2008年1月和12月的《Diabetes Care》和《Diabetologia》上。第一次共识声明内容主要围绕TZDs药物的安全性,本刊作了摘译转载(参阅《中国糖尿病杂志》2008年第7期)。第二次修订的共识声明,关注点为降糖药的新分级,论据及观点比较清晰,故仍摘译供读者参考。 | Nathan DM Buse JB Davidson MB Ferrannini E Holman RR Sherwin R Zinman B 钱荣立(摘译) | 2009 | 中国糖尿病杂志2009，17，1： | 2 |
| 6 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 7 | Distinct roles for STAT1, STAT3 and STAT5 indifferentiation gene induction and apoptosis inhibition by interleukin-9 显示文摘 | Demoulin JB Van Roost E Stevens M | 1999 | Biol Chem1999，274，25： | 1 |
| 8 | Increased prevalence and analysis of risk factors for indinavir nephrolithiasis显示文摘 | ANGEL JB FUTTER NG | 2000 | J Urol2000，164，6： | 1 |
| 9 | Cisplatin,fluorouracil,and docetaxel in unresectable head and neck cancer显示文摘 | Vermorken JB Remenar E van Herpen C | 2007 | N Engl J Med2007，357，17： | 1 |
| 10 | Type 2 diabetes and muhidrug-resistant tuberculosis 显示文摘 | FISHER-HOCH SP WHITNEY E MCCORMICK JB | 2008 | Scand J Infect Dis2008，40，1112： | 1 |
| 11 | Endothelins and the cerebral circulation显示文摘 | Salom JB Torregrosa G Alborch E | 1995 | Cercbrovasc Brain Metab Rev1995，7，2： | 1 |
| 12 | Blood lead level in the US population显示文摘 | Debra JB James LP Pirkl E | 1994 | JAMA1994，272，3： | 1 |
| 13 | Cisplatin, Fluorouracil, and Docetaxel in unresectable head and neck cancer 显示文摘 | Vermorken JB Remenar E van Herpen C | 2007 | N Engl J Med2007，357，： | 1 |
| 14 | Microdialysis sampling for investigations of bioavailability and bioequivalence of topically administered drugs:current state and future perspectives显示文摘 | Holmgaard R Nielsen JB Benfeldt E | 2010 | Skin Pharmacol Physiol2010，23，5： | 1 |
| 15 | Alteration of left ventricular filling evaluated by Doppler echocardiography as a potential marker of acute rejection in orthotopic heart transplant显示文摘 | Pellicelli AM Cosial JB Ferranti E | 1996 | Angiology1996，3541，： | 1 |
| 16 | An Epstein-Barr virus tra-associated membrane protein interacts with src fanuky tyrosine kibases显示文摘 | Burkhardt AL Bolen JB Kieff E | 1992 | J Virol1992，66，8： | 1 |
| 17 | Cortical sensorimotor reorganization after spinal cord injury: an electroencephalographic study显示文摘 | Green JB Sora E Bialy Y | 1998 | Neurology1998，50，4： | 1 |
| 18 | Vacuolar cation/H^+ exchange, ion homeostasis, and leaf development are altered in a T-DNA insertional mutant of AtNHXI, the Arabidopsis vacuolar Na^+/H+ antiporter显示文摘 | Apse MP Sottosanto JB Blumwald E | 2003 | The Plant Journal2003，36，： | 1 |
| 19 | Patient dose from CT:a literature review显示文摘 | Colang JE Killion JB Vano E | 2007 | Radiol Technol2007，79，： | 1 |
| 20 | A single tyrosine of the interleukin-9(IL-9) receptor is required for STAT activation,antiapoptotic activity,and growth regulation by IL-9显示文摘 | Demoulin JB Uyttenhove C Van Roost E | 1996 | Mol Cell Biol1996，16，9： | 1 |
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