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| 1 | Perianal disease,small bowel disease,smoking,prior steroid or early azathioprine/biological therapy are predictors of disease behavior change in patients with Crohn's disease显示文摘AIM:To assess the combined effect of disease phenotype, smoking and medical therapy [steroid, azathioprine(AZA), AZA/biological therapy] on the probability of disease behavior change in a Caucasian cohort of patients with Crohn's disease(CD).METHODS:Three hundred and forty well-characterized, unrelated, consecutive CD patients were analyzed(M/F:155/185, duration:9.4 ± 7.5 years) with a complete clinical follow-up.Medical records including disease phenotype according to the Montreal classification, extraintestinal manifestations, use of medications and surgical events were analyzed retrospectively.Patients were interviewed on their smoking habits at the time of diagnosis and during the regular follow-up visits.RESULTS:A change in disease behavior was observed in 30.8% of patients with an initially non-stricturing, non-penetrating disease behavior after a mean diseaseduration of 9.0 ± 7.2 years.In a logistic regression analysis corrected for disease duration, perianal disease, smoking, steroid use, early AZA or AZA/ biological therapy use were independent predictors of disease behavior change.In a subsequent Kaplan-Meier survival analysis and a proportional Cox regression analysis, disease location(P = 0.001), presence of perianal disease(P < 0.001), prior steroid use(P = 0.006), early AZA(P = 0.005) or AZA/biological therapy(P = 0.002), or smoking(P = 0.032) were independent predictors of disease behavior change.CONCLUSION:Our data suggest that perianal disease, small bowel disease, smoking, prior steroid use, early AZA or AZA/biological therapy are all predictors of disease behavior change in CD patients. | Peter Laszlo Lakatos Zsofia Czegledi Tamas Szamosi Janos Banai Gyula David Ferenc Zsigmond Tunde Pandur Zsuzsanna Erdelyi Orsolya Gemela Janos Papp Laszlo Lakatos | 2009 | World Journal of Gastroenterology2009，15，28： | 14 |
| 2 | Blood flow restriction in human skeletal muscle during rest periods after high-load resistance training down-regulates miR-206 and induces Pax7显示文摘Backgroud:Blood flow re striction(BFR) with low-intensity re sistance training has been shown to result in hypertrophy of skeletal muscle.In this study,we tested the hypothesis that BFR during the rest periods between acute,high-intensity resistance exercise sessions(70% of 1 repetition maximum,7 sets with 10 repetitions) enhances the effects of the resistance training.Methods:A total of 7 healthy young men performed squats,and between sets BFR was carried out on one leg while the other leg served as a control.Because BFR was applied during rest periods,even severe occlusion pressure(approximately 230 mmHg),which almost completely blocked blood flow,was well-tolerated by the participants.Five muscle-specific microRNAs were measured from the biopsy samples,which were taken 2 h after the acute training.Results:Doppler data showed that the pattern of blood flow recovery changed significantly between the first and last BFR.microRNA-206 levels significantly decreased in the BFR leg compared to the control.The mRNA levels of RAC-β serine/threonine-protein kinase v22,nuclear re spiratory factor 1,vascular endothelial growth factor,lupus Ku autoantigen protein p70 genes(p <0.05),and paired box 7(p <0.01) increased in the BFR leg.The protein levels of paired box 7,nuclear respiratory factor 1,and peroxisome proliferator-activated receptor y coactivator 1α did not differ between the BFR leg and the control leg.Conclusion:BFR,during the rest periods of high-load resistance training,could lead to mRNA elevation of those proteins that regulate angiogenesis,mitochondrial biogenesis,and muscle hypertrophy and repair.However,BFR also can cause DNA damage,judging from the increase in mRNA levels of lupus Ku autoantigen protein p70. | Ferenc Torma Zoltan Gombos Marcell Fridvalszki Gergely Langmar Zsofia Tarcza Bela Merkely Hisashi Naito Noriko Ichinoseki-Sekine Masaki Takeda Zsolt Murlasits Peter Osvath Zsolt Radak | 2021 | Journal of Sport and Health Science2021，10，4： | 3 |
| 3 | Hypokalemic myopathy in a patient with gluten-sensitive enteropathy and dermatitis herpetiformis Duhring: A case report显示文摘The case of a 22-year-old patient with symptomatic hypokalemia caused by rhabdomyolysis is presented as a rarely reported complication of gluten-sensitive enteropathy (GSE) and dermatitis herpetiformis Duhring. The patient's myopathy ceased on potassium supplementation and her other complaints resolved while on gluten-free diet.Recovery was otherwise uneventful with a rapid decline in serum CPK level. At the time of her last follow-up a few months later, she was free of symptoms and CPK remained stable. Patients with GSE may present with hypokalemia in association with diarrhea and emesis, and if potassium loss is rapid, rhabdomyolysis may occur. | Zsolt Barta Zsofia Miltenyi Laszlo Toth Arpad Illes | 2005 | World Journal of Gastroenterology2005，11，13： | 2 |
| 4 | A Prospective, Randomized Trial to Evaluate the Efficacy of Virtual Reality Treatment Versus Traditional Balance Treatment in Patients with Stroke显示文摘 | Zsanett Sipos Zsofia Hogye Zsuzsanna Vekerdy-Nagy | 2016 | Journal of Sports Science2016，4，3： | 2 |
| 5 | Recovery of N and P from human urine by freezing, struvite precipitation and adsorption to zeolite and active carbon显示文摘 | Ganrot Zsofia Dave Goran Nilsson Eva | 2007 | Bioresource Technology2007，98，16： | 1 |
| 6 | Adsorption of propisochlor on soils and soil components equation for multi-step isotherms显示文摘 | Imre Czinkota Rita Foldenyi Zsofia Lengyel | 2002 | Chemosphere2002，48，： | 1 |
| 7 | A consumption-based approach to carbon emission accounting-sectoral differences and environmental benefits 显示文摘 | Zsofia Vetone Mozner | 2013 | Journal of Cleaner Production2013，42，3： | 1 |
| 8 | Spatio-temporality in narrative fiction: Humboldt's Gift by Saul Bellow显示文摘 | Zsofia S | 2006 | Argumentum2006，，2： | 1 |
| 9 | Aptamer-based biochips for label-free detection of plant virus coat proteins by SPR imaging显示文摘 | GERGELY L ZSOFIA B VIOLA B | 2010 | The Analyst2010，135，5： | 1 |
| 10 | Recovery of N and P from human urine by freezing, struvite precipitation and adsorption to zeolite and active carbon显示文摘 | Ganrot Zsofia DaveGran NilssonEva | 2007 | Biores ource Technology2007，98，16： | 1 |
| 11 | Parametric Bayesian filters for nonlinear stochastic dynamical systems:A survey显示文摘 | Pawe S Zsofia L Jelmer B | 2013 | IEEE Trans on Cybernetics2013，43，6： | 1 |
| 12 | Adsorption of propisochlor on soils and soil components equation for multi-step isotherms 显示文摘 | Imre Czinkota Rita Foldenyi Zsofia Lengyel | 2002 | Chemosphere2002，48，： | 1 |
| 13 | Manipulating the mammalian genome by homologous recombination显示文摘 | Karen MV Kathleen M Zsofia I | 2001 | Proc Natl Aead Sci USA2001，98，： | 1 |
| 14 | Manipulating the mammalian genome by homologous recombination 显示文摘 | Karen M V Kathleen M Zsofia I | 2001 | Proc Natl Aead Sci USA2001，98，： | 1 |
| 15 | Short beak and dwarfism syndrome of mule duck is caused by a distinct lineage of goose parvovirus显示文摘 | Vilmos Palya Anna Zolnai Zsofia Benyeda Edit Kovacs Veronika Kardi Tamas Mato | 2009 | Avian Pathology2009，，2： | 1 |
| 16 | Systematic Immunohistochemistry Screening for Lynch Syndrome in Early Age-of-Onset Colorectal Cancer Patients Undergoing Surgical Resection显示文摘 | Emily Steinhagen Jinru Shia Arnold J. Markowitz Zsofia K. Stadler Erin E. Salo-Mullen Junting Zheng Steven A. Lee-Kong Garrett M. Nash Kenneth Offit José G. Guillem | 2012 | Journal of the American College of Surgeons2012，，1： | 1 |
| 17 | Juvenile Polyposis Syndrome Presenting With Familial Gastric Cancer and Massive Gastric Polyposis显示文摘 | Zsofia K. Stadler Erin Salo-Mullen Liying Zhang Jinru Shia Ruben Bacares Derek G. Power Martin Weiser Daniel Coit Mark E. Robson Kenneth Offit Mark Schattner | 2012 | Journal of Clinical Oncology2012，，25： | 1 |
| 18 | Lymph Node Yield After Colectomy for Cancer: Is Absence of Mismatch Repair a Factor?显示文摘 | Tushar Samdani Molly Schultheis Zsofia Stadler Jinru Shia Tiffany Fancher Justine Misholy Martin R. Weiser Garrett M. Nash | 2015 | Diseases of the Colon & Rectum2015，，： | 1 |
| 19 | A consumption-based approach to car-bon emission accountinge sectoral differences and environ-mental benefits 显示文摘 | Zsofia Vetone Mozner | 2013 | Joumal of Cleaner Production2013，，42： | 1 |
| 20 | Cellulase fermentation on a novel substrate(waste cardboard)and subsequent utilization of home-produced cellulase and commercial amylase in a rabbit feeding trial显示文摘 | Nora Szijarto Zsofia Faigl | 2004 | Industrial Crop and Products2004，20，1： | 1 |
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