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| 1 | Modern management of rectal cancer: A 2006 update显示文摘The goal of this review is to outline some of the important surgical issues surrounding the management of patients with early (T1/T2 and NO), as well as locally advanced (T3/T4 and/or N1) rectal cancer. Surgery for rectal cancer continues to develop towards the ultimate goals of improved local control and overall survival, maintaining quality of life, and preserving sphincter, genitourinary, and sexual function. Information concerning the depth of tumor penetration through the rectal wall, lymph node involvement, and presence of distant metastatic disease is of crucial importance when planning a curative rectal cancer resection. Preoperative staging is used to determine the indication for neoadjuvant therapy as well as the indication for local excision versus radical cancer resection. Local excision is likely to be curative in most patients with a primary tumor which is limited to the submucosa (T1N0M0), without high-risk features and in the absence of metastatic disease. In appropriate patients, minimally invasive procedures, such as local excision, TEM, and laparoscopic resection allow for improved patient comfort, shorter hospital stays, and earlier return to preoperative activity level. Once the tumor invades the muscularis propria (T2), radical rectal resection in acceptable operative candidates is recommended. In patients with transmural and/or node positive disease (T3/T4 and/or N1) with no distant metastases, preoperative chemoradiation followed by radical resection according to the principles of TME has become widely accepted. During the planning and conduct of a radical operation for a locally advanced rectal cancer, a number of surgical management issues are considered, including: (1) total mesorectal excision (TME); (2) autonomic nerve preservation (ANP); (3) circumferential resection margin (CRM); (4) distal resection margin; (5) sphincter preservation and options for restoration of bowel continuity; (6) laparoscopic approaches; and (7) postoperative quality of life. | Glen C Balch Alex De Meo Jose G Guillem | 2006 | World Journal of Gastroenterology2006，12，20： | 26 |
| 2 | SCPE的工作、标准化和定义—SCPE活动概貌:欧洲脑瘫登记协作网(英文)显示文摘欧洲脑瘫监测组织(SurveillanceofCerebralPalsyinEurope,SCPE)协作网络的主要目的是建立欧洲脑瘫病例的中央数据库。对脑瘫患病率变化趋势的监控有利于对脑瘫危险因素的研究以及提高脑瘫患儿的生活质量。在脑瘫多中心协作登记工作中,为了准确一致地鉴定脑瘫病例,研究人员采用明确、统一的脑瘫定义。SCPE协作组发现每1000个存活儿中脑瘫的患病例为1.5~3例。在1980至1996年间的出生组群中(n=9128),53.9%的脑瘫患儿为双侧痉挛性脑瘫,31.0%的为单侧痉挛性脑瘫,6.6%为运动障碍,4.1%为共济失调。在脑瘫患儿中,20.4%患儿出生体重不足1500g,而25.5%的孕龄不足32周。29.5%的脑瘫患儿出现了智力障碍(IQ<50)。不能步行(甚至在协助下)的脑瘫患儿比例为30.3%。12.5%的脑瘫患儿出现了严重的视力缺损。做好登记工作有助于了解脑瘫流行病学的特征,是进行脑瘫流行病学研究的一种最佳方式。 | Vicki McManus Pascale Guillem Geraldine Surman Christine Cans | 2006 | 中国当代儿科杂志2006，8，4： | 10 |
| 3 | Safety and Efficacy of Low Anterior Resection for Rectal Cancer: 681 Consecutive Cases From a Specialty Service显示文摘 | Warren E. Enker Nipun Merchant Alfred M. Cohen Nicole M. Lanouette Carol Swallow Jose Guillem Philip Paty Bruce Minsky Katherine Weyrauch Stuart H. Q. Quan | 1999 | Annals of Surgery1999，，4： | 3 |
| 4 | Chatter in machining processes: A review显示文摘 | Guillem Quintana Joaquim Ciurana | 2011 | International Journal of Machine Tools and Manufacture2011，，5： | 2 |
| 5 | A Predictive Model for Lymph Node Yield in Colon Cancer Resection Specimens显示文摘 | Garrett M. Nash David Row Alexander Weiss Jinru Shia Jose G. Guillem Philip B. Paty Mithat Gonen Martin R. Weiser Larissa K. Temple Garrett Fitzmaurice W. Douglas Wong | 2011 | Annals of Surgery2011，，2： | 2 |
| 6 | Nonoperative Management of Rectal Cancer With Complete Clinical Response After Neoadjuvant Therapy显示文摘 | James D. Smith Jeannine A. Ruby Karyn A. Goodman Leonard B. Saltz José G. Guillem Martin R. Weiser Larissa K. Temple Garrett M. Nash Philip B. Paty | 2012 | Annals of Surgery2012，，6： | 2 |
| 7 | Sphincter Preservation in Low Rectal Cancer is Facilitated by Preoperative Chemoradiation and Intersphincteric Dissection显示文摘 | Martin R. Weiser Hak-Mien Quah Jinru Shia José G. Guillem Philip B. Paty Larissa K. Temple Karyn A. Goodman Bruce D. Minsky W Douglas Wong | 2009 | Annals of Surgery2009，，2： | 2 |
| 8 | The cognitive and anatomo-functional basis of reality distortion in schizophrenia:A view from memory event-related potentials显示文摘 | Guillem F Bicu M Pampoulova T | 2003 | Psychiatry Res2003，117，2： | 1 |
| 9 | ASCO/SSO re-view of current role of risk-reducing surgery in common he-reditary cancer syndromes显示文摘 | Guillem J G Wood W C Moley J F | 2006 | J Clin Oncol2006，24，28： | 1 |
| 10 | the Multi-angle View o{ MI SR Detects Oil Slicks Under Sun Glitter Conditions 显示文摘 | Guillem C Yolanda S | 2007 | Remote Sensing of Environment2007，，23： | 1 |
| 11 | A prospective pathologic analysis using whole-mount sections of rectal cancer following preoperative combined modality therapy: implications for sphincter preservation显示文摘 | Guillem JG Chessin DB Shia J | 2007 | Ann Surg2007，245，1： | 1 |
| 12 | Telomerase and telomerc length in the development and progression of premalignant lesions to colorectal cancer显示文摘 | Engelhardt M Drullinsky P Guillem J | 1997 | Clin Cancer Res1997，3，11： | 1 |
| 13 | Loss of basement membrane type Ⅳ collagen in associated with increased expression of metalloproteinases 2 and 9 (MMP2 and MMP9) during human colorectal tumorigenesis显示文摘 | Zeng ZS Cohen AM Guillem JG | 1999 | Carcinogenesis1999，20，5： | 1 |
| 14 | Loss of basement membrane type Ⅳ collagen is associated with increased expression of metalloprotemases 2 and 9(MMP-2 and MMP-9) during human colorectal tumorigenesis 显示文摘 | Zeng ZS Cohen AM Guillem JG | 1999 | Carcingenesis1999，20，5： | 1 |
| 15 | Loss of basement membrane type Ⅳ collagen is associated with increased expression of metalloprotemases 2 and 9(MMP-2 and MMP-9) during human colorectal tumorigenesis 显示文摘 | Zeng ZS Cohen AM Guillem JG | 1999 | Carcinogenesis1999，20，5： | 1 |
| 16 | Are there common mechanisms in sensation seeking and reality distortion in schizophrenia? A study using memory event-related potentials显示文摘 | Guillem F Pampoulova T Stip E | 2005 | Psychiatry Res2005，135，1： | 1 |
| 17 | Telomerase and telomere length in the development and progression of premalignant lesions to colorectal cancer显示文摘 | Engelhardt M Drullinsky P Guillem J | 1997 | Clin Cancer Res1997，3，11： | 1 |
| 18 | Loss of basement membrane type IV collagen is associated with increased expression of metalloproteinases 2 and 9 (MMP-2 and MMP-9)during human colorectal tumorigenesis显示文摘 | Zeng ZS Cohen AM Guillem JG | 1999 | Carcinogenesis1999，20，： | 1 |
| 19 | Loss of basement membrane type IV collagen is associated with increased expression of metalloproteinases 2 and 9 (MMP-2 and MMP-9) during human colorectal tumorigenesis 显示文摘 | Zeng ZS Cohen AM Guillem JG | 1999 | Carcinogenesis1999，20，5： | 1 |
| 20 | Squamous-Cell Carcinoma of the Rectum: A Rare but Curable Tumor显示文摘 | Caio S. R. Nahas M.D. Jinru Shia M.D. Romane Joseph M.D. Deborah Schrag M.D. Bruce D. Minsky M.D. Martin R. Weiser M.D. Jose G. Guillem M.D. Phillip B. Paty M.D. David S. Klimstra M.D. Laura H. Tang M.D. W. Douglas Wong M.D. Larissa K. Temple M.D | 2007 | Diseases of the Colon & Rectum2007，，9： | 1 |
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