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| 1 | Characteristics of hydrocarbon accumulation and exploration potential of the northern South China Sea deepwater basins显示文摘Although the huge potential of the northern South China Sea deepwater basins has been proven by a series of discoveries that followed the exploration breakthrough of well LW 3-1-1, recent drilling and other studies have demonstrated the uniqueness and complicated nature of hydrocarbon accumulations of the deepwater basins there. Based on a review of previous work and the latest exploration activities and studies, the purpose of this paper is to discuss the critical controls for hydrocarbon accumulations in the deepwater basins of the northern South China Sea. A terrestrial-marine transitional coal-bearing source rock is proposed to be the primary source rock for the deepwater basins. A marine source rock, which was first identified as contributing to hydro-carbon generation in this region, probably plays a significant role in the deep-and ultra-deep water basins south to the Pearl River Mouth and Qingdongnan basins. The shelf margin delta depositional systems in the Baiyun Sag, sourced from the Pearl River, are currently primary exploration targets in the deepwater part of the Pearl River Mouth Basin, whereas the western Red River delta-ic-submarine fan depositional systems, initially proven by drilling, are the possible major exploration reservoirs in the Qing-dongnan deepwater areas. Current deepwater exploration targets at the large-sized structural traps and deep and ultra-deep areas in the south of the Pearl River Mouth and Qingdongnan basins will be the future exploration focus. Deepwater exploration activities and relevant fundamental studies, supporting and promoting each other, are of great importance to the national energy supply of China, the basic regional studies of the South China Sea, advancements in technology, and development of related deepwater industries, and will safeguard national sovereignty and territorial integrity. | ZHU WeiLin ZHONG Kai LI YouChuan XU Qiang FANG DianYong | 2012 | Chinese Science Bulletin2012，57，24： | 48 |
| 2 | 盆地演化认识中的几个问题显示文摘本文论述了盆地演化认识中的几个主要问题。一是陆缘裂解过程,华南边缘传统上认为是被动裂谷边缘的一个例子,其东部沉积物记录了压实的历史,它明显不同于被动裂谷作用模式,而是显示早第三纪大规模上隆和侵蚀的特征;而且,该地区覆盖在下地壳楔形体上面,具有比周围地壳明显要高的地震速度和密度,指示岩浆底侵作用。这些证据说明,与被动裂谷作用模式相比,华南边缘与主动裂谷作用模式较为一致,它是由早第三纪华南边缘东部底下地幔柱形成的主动裂谷。另一个问题是关于页岩的浅部破裂作用机理。大多数研究者认为,微裂隙的形成需要高孔隙压力,它限于深埋、低渗透率的岩石。然而,最近从北海观察表明,在第三纪页岩中,整个盆地范围内的破裂型式从未达到大于几百米的埋藏深度。这说明泥质源岩经历了水压破裂和浅部脱水,在破裂前可能达到深埋后生作用所需要的深度,实质上渗透率的改变是由于源岩的浅部破裂作用可能根本上改变了烃类的初次运移时间和效率。 | Wang Chiyuen(Department of Geology and Geophysics University of California,Berkeley,CA 94720)Yang Jiaming Zhu Weilin(Exploration and Development Research Center,China National Offshore Oil Corporation,Xincheng,074010)Zheng Mingling(Scientific Research Ce | 1995 | 地学前缘1995，2，3： | 14 |
| 3 | New insights on the origin of the basement of the Xisha Uplift,South China Sea显示文摘The study of basement geochronology provides crucial insights into the tectonic evolution of oceans. However, early studies on the basement of the Xisha Uplift were constrained by limited geophysical and seismic data; Xiyong1 was the only commercial borehole drilled during the 1970 s because of the huge thickness of overlying Cenozoic strata on the continental margin. Utilizing two newly-acquired basement samples from borehole XK1, we present petrological analysis and zircon uranium(U)-lead(Pb) isotope dating data in this paper that enhance our understanding of the formation and tectonic features of the Xisha Uplift basement. Results indicate that this basement is composed of Late Jurassic amphibole plagiogneisses that have an average zircon 206 Pb/238 U age of 152.9±1.7 Ma. However, the youngest age of these rocks, 137±1 Ma, also suggests that metamorphism termination within the Xisha basement occurred by the Early Cretaceous. These metamorphic rocks have adamellites underneath them which were formed by magmatic intrusions during the late stage of the Early Cretaceous(107.8±3.6 Ma). Thus, in contrast to the Precambrian age(bulk rubidium(Rb)-strontium(Sr) analysis, 627 Ma) suggested by previous work on the nearby Xiyong1 borehole, zircons from XK1 are likely the product of Late Mesozoic igneous activity. Late Jurassic-Early Cretaceous regional metamorphism and granitic intrusions are not confined to Xisha; rocks have also been documented from areas including the Pearl River Mouth Basin and the Nansha Islands(Spratly Islands) and thus are likely closely related to large-scale and long-lasting subduction of the paleo-Pacific plate underneath the continental margins of East Asia, perhaps the result of closure of the Meso-Tethys in the South China Sea(SCS). Controversies remain as to whether, or not, the SCS region developed initially on a uniform Precambrian-aged metamorphic crystalline basement. It is clear, however, that by this time both Mesozoic compressive subduction and Cenozoic rifting and extension had significantly modified the original basement of the SCS region. | ZHU WeiLin XIE XiNong WANG ZhenFeng ZHANG DaoJun ZHANG ChengLi CAO LiCheng SHAO Lei | 2017 | Science China Earth Sciences2017，60，12： | 10 |
| 4 | Distribution characteristics of seamount cobalt-rich ferromanganese crusts and the determination of the size of areas for exploration and exploitation显示文摘In 2001,the International Seabed Authority (ISBA) initiated the consideration relating to the Regulations for Prospecting and Exploration for Hydrothermal Polymetallic Sulphides and Cobalt-rich Ferromanganese Crusts in the Area at its 7th session.Since then,the consideration of the Regulations has been mainly focused on the size of areas to be allocated for exploration and exploitation of the crusts.This paper,based on the investigation data and the analysis of the distribution characteristics of the crusts,suggests a model for determining the size of areas for exploration and exploitation of the crusts,taking into account various factors such as production scale,crust thickness and grade,mineable area proportion,recovery efficiency,exploration venture,and so on.Through the modeling, the paper suggests that the exploration area (the area covered by each application for approval of a plan of work for exploration of cobalt-rich crusts) shall be 4 856 km 2 and the exploitation area (the mine site area) shall be 1 214 km 2,for 20 years of 1 million wet tonnes annual production. | HE Gaowen MA Weilin SONG Chengbing YANG Shengxiong ZHU Benduo YAO Huiqiang JIANG Xunxiong CHENG Yongshou | 2011 | Acta Oceanologica Sinica2011，30，3： | 9 |
| 5 | Initial Results of Lidar Measured Middle Atmosphere Temperatures over Tibetan Plateau显示文摘During August 2013,a mobile Rayleigh lidar was deployed in Lhasa,Tibet(29.6°N,91.0°E) for making measurements of middle atmosphere densities and temperatures from 30 to 90 km.In this paper,the authors present the initial results from this scientific campaign,Middle Atmosphere Remote Mobile Observatory in Tibet(MARMOT),and compared the results to the MSIS-00(Mass Spectrometer and Incoherent Scatter) model.This work will advance our understanding of middle atmosphere dynamic processes,especially over the Tibetan Plateau area. | QIAO Shuai PAN Weilin ZHU Ke-Yun ZOU Rong-Shi TAN Jing | 2014 | Atmospheric and Oceanic Science Letters2014，7，3： | 8 |
| 6 | Characterization of Carotenoid Accumulation and Carotenogenic Gene Expression During Fruit Development in Yellow and White Loquat Fruit显示文摘Accumulation of carotenoids in peel and pulp of the yellow-fleshe loquat ‘Zaozhong 6'(ZZ6) and the white-fleshe loquat ‘Baiyu'(BY) were tracked during different fruit development stages, and the expression of 15 carotenogenic genes were analyzed. During loquat fruit ripening the fresh weight content of β-carotene in peel and pulp of ZZ6 increased gradually and peaked at the fully ripe stage, reaching 68.53 μg·g^(-1)FW in the peel and 11.92 μg·g^(-1)FW in the pulp. In BY, the content of β-carotene in the peel increased and peaked at the fully ripe stage, reaching38.89 μg·g^(-1)FW, while it decreased in the pulp from the original 0.47 μg·g~(^(-1))FW and reduced to 0.29 μg·g~(^(-1))FW. The content of β-cryptoxanthin in the peel and pulp of ZZ6 and BY both increased steadily, and peaked at the fully ripe stage; however, the content of lutein decreased in the peel of ZZ6 and increased in the pulp, but in BY, it dropped and then rose in the peel. There was no significan change of β-cryptoxanthin in the pulp of BY. After the breaker stage, the m RNA levels of phytoene synthase(PSY) and chromoplast-specifi lycopene β-cyclase(CYCB) were higher in the peel, while CYCB and β-carotene hydroxylase(BCH) m RNAs were higher in the fles of ZZ6, compared with BY. The results showed that the expression level of PSY, CYCB, and BCH appeared to cooperatively regulate the accumulation of carotenoids. | ZHANG Ling ZHANG Zhike ZHENG Tingting WEI Weilin ZHU Yunmei GAO Yongshun YANG Xianghui LIN Shunquan | 2016 | Horticultural Plant Journal2016，2，1： | 6 |
| 7 | Migration of multiples from the South China Sea显示文摘The South China Sea where water depth is up to 5000 m is the most promising oil and gas exploration area in China in the future.The seismic data acquired in the South China Sea contain various types of multiples that need to be removed before imaging can be developed.However,compared with the conventional reflection migration,multiples carry more information of the underground structure that helps provide better subsurface imaging.This paper presents a method to modify the conventional reverse time migration so that multiple reflections can migrate to their correct locations in the subsurface.This approach replaces the numerical impulsive source with the recorded data including primaries and multiples on the surface,and replaces the recorded primary reflection data with multiples.In the reverse time migration process,multiples recorded on the surface are extrapolated backward in time to each depth level,while primaries and multiples recorded on the surface are extrapolated forward in time to the same depth levels.By matching the difference between the primary and multiple images using an objective function,this algorithm improves the primary resultant image.Synthetic tests on Sigsbee2 B show that the proposed method can obtain a greater range and better underground illumination.Images of deep water in the South China Sea are obtained using multiples and their matching with primaries.They demonstrate that multiples can make up for the reflection illumination and the migration of multiples is an important research direction in the future. | LIU YiKe ZHU WeiLin MI LiJun ZHOU JiaXiong HAO Hu | 2015 | Science China Earth Sciences2015，58，3： | 6 |
| 8 | Cartilage-targeting peptide-modified dual-drug delivery nanoplatform with NIR laser response for osteoarthritis therapy显示文摘Cartilage-targeting delivery of therapeutic agents is still an effective strategy for osteoarthritis(OA)therapy.Recently,scavenging for reactive oxygen species(ROS)and activating autophagy have been increasingly reported to treat OA effectively.In this study,we designed,for the first time,a dual-drug delivery system based on metal organic framework(MOF)-decorated mesoporous polydopamine(MPDA)which composed of rapamycin(Rap)loaded into the mesopores and bilirubin(Br)loaded onto the shell of MOF.The collagen II-targeting peptide(WYRGRL)was then conjugated on the surface of above nanocarrier to develop a cartilage-targeting dual-drug delivery nanoplatform(RB@MPMW).Our results indicated the sequential release of two agents from RB@MPMW could be achieved via near-infrared(NIR)laser irritation.Briefly,the rapid release of Br from the MOF shell exhibited excellent ROS scavenging ability and anti-apoptosis effects,however responsively reduced autophagy activity,to a certain extent.Meanwhile,following the NIR irradiation,Rap was rapidly released from MPDA core and further enhanced autophagy activation and chondrocyte protection.RB@MPMW continuously phosphorylated AMPK and further rescued mitochondrial energy metabolism of chondrocytes following IL-1βstimulation via activating SIRT1-PGC-1αsignaling pathway.Additionally,the cartilage-targeting property of peptide-modified nanocarrier could be monitored via Magnetic Resonance(MR)and IVIS imaging.More significantly,RB@MPMW effectively delayed cartilage degeneration in ACLT rat model.Overall,our findings indicated that the as-prepared dual-drug delivery nanoplatform exerted potent anti-inflammation and anti-apoptotic effects,rescued energy metabolism of chondrocytes in vitro and prevented cartilage degeneration in vivo,which thereby showed positive performance for OA therapy. | Song Xue Xiaojun Zhou Weilin Sang Cong Wang Haiming Lu Yiming Xu Yiming Zhong Libo Zhu Chuanglong He Jinzhong Ma | 2021 | Bioactive Materials2021，6，8： | 5 |
| 9 | Chinese expert consensus on conversion therapy for hepatocellular carcinoma(2021 edition)显示文摘Recent advances in systemic and locoregional treatments for patients with unresectable or advanced hepatocellular carcinoma(HCC)have resulted in improved response rates.This has provided an opportunity for selected patients with initially unresectable HCC to achieve adequate tumor downstaging to undergo surgical resection,a‘conversion therapy’strategy.However,conversion therapy is a new approach to the treatment of HCC and its practice and treatment protocols are still being developed.Review the evidence for conversion therapy in HCC and develop consensus statements to guide clinical practice.Evidence review:Many research centers in China have accumulated significant experience implementing HCC conversion therapy.Preliminary findings and data have shown that conversion therapy represents an important strategy to maximize the survival of selected patients with intermediate stage to advanced HCC;however,there are still many urgent clinical and scientific challenges for this therapeutic strategy and its related fields.In order to summarize and learn from past experience and review current challenges,the Chinese Expert Consensus on Conversion Therapy for Hepatocellular Carcinoma(2021 Edition)was developed based on a review of preliminary experience and clinical data from Chinese and non-Chinese studies in this field and combined with recommendations for clinical practice.Sixteen consensus statements on the implementation of conversion therapy for HCC were developed.The statements generated in this review are based on a review of clinical evidence and real clinical experience and will help guide future progress in conversion therapy for patients with HCC. | Hui-Chuan Sun Jian Zhou Zheng Wang Xiufeng Liu Qing Xie Weidong Jia Ming Zhao Xinyu Bi Gong Li Xueli Bai Yuan Ji Li Xu Xiao-Dong Zhu Dousheng Bai Yajin Chen Yongjun Chen Chaoliu Dai Rongping Guo Wenzhi Guo Chunyi Hao Tao Huang Zhiyong Huang Deyu Li Gang Li Tao Li Xiangcheng Li Guangming Li Xiao Liang Jingfeng Liu Fubao Liu Shichun Lu Zheng Lu Weifu Lv Yilei Mao Guoliang Shao Yinghong Shi Tianqiang Song Guang Tan Yunqiang Tang Kaishan Tao Chidan Wan Guangyi Wang Lu Wang Shunxiang Wang Tianfu Wen Baocai Xing Bangde Xiang Sheng Yan Dinghua Yang Guowen Yin Tao Yin Zhenyu Yin Zhengping Yu Bixiang Zhang Jialin Zhang Shuijun Zhang Ti Zhang Yamin Zhang Yubao Zhang Aibin Zhang Haitao Zhao Ledu Zhou Wu Zhang Zhenyu Zhu Shukui Qin Feng Shen Xiujun Cai Gaojun Teng Jianqiang Cai Minshan Chen Qiang Li Lianxin Liu Weilin Wang Tingbo Liang Jiahong Dong Xiaoping Chen Xuehao Wang Shusen Zheng Jia Fan 无 | 2022 | Hepatobiliary Surgery and Nutrition2022，11，2： | 4 |
| 10 | Study on Modification of Ultra-Stable Zeolite Prepared by Hydrothermal Method显示文摘极端马厩的沸石 DASY-0.0 被热水的方法在商业规模准备。它的结构进一步为在对待的 CP 被 XRF 分析并且描绘前后, .Thezeolite 取样的毛孔( CP )清洗经由处理被修改, XRD , NMR ,红外, BETand DTA.The 结果显示出那与由热水的过程的常规极端马厩的沸石 DASY-0.0prepared 比较, 修改CP 的沸石 SOYO 展出了更高的 relativecrystallinity ,更大的表面区域和毛孔体积,更高热的稳定性和包含的更少非结晶的非框架艾尔。 | Zhang Weilin Zhou Lingping Shen Shimin Li Zheng Zhu Yuxia Tian Huiping Long Jun | 2007 | China Petroleum Processing & Petrochemical Technology2007，9，2： | 2 |
| 11 | Synthesis of AgGa1-xInxSe2 Polycrystalline Materials显示文摘AgGa1-xInxSe2 polycrystals were synthesized by the method of mechanical oscillation and temperature oscillation. X-ray diffraction spectra of polycrystal powder are conformable with the JCPDS cards. Lattice constants a and c calculated from the XRD were found to obey Vegard's law. The melting point of AgGa0.8In0.2Se2 obtained by means of differential scanning calorimetry (DSC) is 796.53 ℃. The DSC curve also show that there are no other transformation points below the melting point. The results indicate that polycrystalline materials synthesized by the method mentioned above are high-quality and can be used to grow single crystals by the vertical Bridgman technology. | Liu Juan Zhao Beijun Zhu Shifu Huang Yi Zhang Jianjun Zhu Weilin Xu Chengfu Chen Baojun Li Ming He Zhiyu | 2006 | Journal of Rare Earths2006，24，z1： | 2 |
| 12 | Rabies Virus Pseudotyped with CVS-N2C Glycoprotein as a Powerful Tool for Retrograde Neuronal Network Tracing显示文摘Efficient viral vectors for mapping and manipulating long-projection neuronal circuits are crucial in structural and functional studies of the brain. The SAD strain rabies virus with the glycoprotein gene deleted pseudotyped with the N2 C glycoprotein(SAD-RV(DG)-N2 C(G)) shows strong neuro-tropism in cell culture, but its in vivo efficiency for retrograde gene transduction and neuro-tropism have not been systematically characterized.We compared these features in different mouse brain regions for SAD-RV-N2 C(G) and two other widely-used retrograde tracers, SAD-RV(DG)-B19(G) and r AAV2-retro. We found that SAD-RV(DG)-N2 C(G) enhanced the infection efficiency of long-projecting neurons by^10 times but with very similar neuro-tropism, compared with SAD-RV(DG)-B19(G). On the other hand, SAD-RV(DG)-N2 C(G) had an infection efficiency comparable with r AAV2-retro, but a more restricted diffusion range, and broader tropism to different types and regions of longprojecting neuronal populations. These results demonstrate that SAD-RV(DG)-N2 C(G) can serve as an effective retrograde vector for studying neuronal circuits. | Xutao Zhu Kunzhang Lin Qing Liu Xinpei Yue Huijie Mi Xiaoping Huang Xiaobin He Ruiqi Wu Danhao Zheng Dong Wei Liangliang Jia Weilin Wang Anne Manyande Jie Wang Zhijian Zhang Fuqiang Xu | 2020 | Neuroscience Bulletin2020，36，3： | 2 |
| 13 | Wave‑Shaped Piezoelectric Nanofber Membrane Nanogenerator for Acoustic Detection and Recognition显示文摘With the rapid development of internet of things and wearable electronics,how to conveniently power uncountable sensors remains a huge challenge.Energy harvesting strategy is suggested to collect and convert environmental energies into electrical energy.Thereinto,piezoelectric polymers are utilized as fexible harvesters to convert mechanical energy.The latter widely distributes in both our daily life and industrial environment.Intrinsic piezoelectric property further drives piezoelectric polymers to construct fexible self-powered strain sensors.However,relatively low piezoelectric performance restricts their application in detection and conversion of weak mechanical excitations.Herein,wave-shaped 3D piezoelectric device was fabricated by embossing electrospun polyvinylidene fuoride nanofbers.This 3D structured device presents better longitudinal and transverse piezoelectric performance than usual fat-type one.This wave-shaped piezoelectric device was developed for acoustic detection and recognition with a frequency resolution better than 0.1 Hz.This wave-shaped device was capable of frequency spectrum analyses of various sound sources from human and animals and well presents its potential for future wearable acoustic sensors and transducers. | Fan Xu Jiang Yang Ruizhi Dong Hanxiao Jiang Conghuan Wang Weilin Liu Zaixiu Jiang Xiaoqing Zhang Guodong Zhu | 2021 | Advanced Fiber Materials2021，3，6： | 2 |
| 14 | Deep Learning-Based Classification of the Polar Emotions of“Moe”-Style Cartoon Pictures显示文摘The cartoon animation industry has developed into a huge industrial chain with a large potential market involving games,digital entertainment,and other industries.However,due to the coarse-grained classification of cartoon materials,cartoon animators can hardly find relevant materials during the process of creation.The polar emotions of cartoon materials are an important reference for creators as they can help them easily obtain the pictures they need.Some methods for obtaining the emotions of cartoon pictures have been proposed,but most of these focus on expression recognition.Meanwhile,other emotion recognition methods are not ideal for use as cartoon materials.We propose a deep learning-based method to classify the polar emotions of the cartoon pictures of the'Moe'drawing style.According to the expression feature of the cartoon characters of this drawing style,we recognize the facial expressions of cartoon characters and extract the scene and facial features of the cartoon images.Then,we correct the emotions of the pictures obtained by the expression recognition according to the scene features.Finally,we can obtain the polar emotions of corresponding picture.We designed a dataset and performed verification tests on it,achieving 81.9%experimental accuracy.The experimental results prove that our method is competitive. | Qinchen Cao Weilin Zhang Yonghua Zhu | 2021 | Tsinghua Science and Technology2021，26，3： | 2 |
| 15 | A Green Processfor the Oxidative Lactonization of 1,2-Benzenedimethanol byTungstic Acid with Aqueous H202 显示文摘 | Zhu Quanjing Dai Weilin Fan Kannian | 2010 | Green Chem2010，12，2： | 1 |
| 16 | A co-simulation method as an enabler for jointly analysis of MAS-based electrical power protection and communication显示文摘 | LI Weilin LUO Min ZHU Lin | 2013 | Transactions of the Society for Modeling and Simulation International2013，5，： | 1 |
| 17 | TAT-Mediated Protein Transduction of Nogo Extracellular Peptide 1-40 and its Biological Activity显示文摘 | Qiang Wang Xingchun Gou Weilin Jin Lize Xiong Lichao Hou Shaoyang Chen Hui Zhang Xiaoling Zhu Lixian Xu | 2009 | Cellular and Molecular Neurobiology2009，，： | 1 |
| 18 | Mitofusin-2 is a novel direct target of p53显示文摘 | Weilin Wang Xiaofei Cheng Jianju Lu Jianfeng Wei Guanghou Fu Feng Zhu Changku Jia Lin Zhou Haiyang Xie Shusen Zheng | 2010 | Biochemical and Biophysical Research Communications2010，，4： | 1 |
| 19 | Upper Miocene to Quaternary unidirectionally migrating deep- water channels in the Pearl River Mouth Basin, northern South China Sea 显示文摘 | Gong Chenglin Wang Yingmin Zhu Weilin | 2013 | AAPG Bulletin2013，97，2： | 1 |
| 20 | FOCUS: PUNITIVE DAMAGES IN CHINA A STUDY ON PUNITIVE DAMAGES IN CHINA显示文摘 | ZHU Yan PAN Weilin | 2014 | Frontiers of Law in China-Selected Publications from Chinese Universities2014，9，3： | 1 |
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