|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Chromosomal Constitutions and Reactions to Powdery Mildew and Stripe Rust of Four Novel Wheat-Thinopyrum intermedium Partial Amphiploids显示文摘As a staple food crop for one-third of the world's population,common wheat(Triticum aestivum L.,2n=6x=42,AABBDD)plays an important role in humans'food security.However,the genetic variation of cultivated wheat has been dramatically narrowed by genetic erosion under the modern cultivation system,resulting in vulnerability to biotic and abiotic stresses(Jiang et al.,1994;Friebe et al.,1996).The wild relatives of wheat | Yinguang Bao Xia Wu Chao Zhang Xingfeng Li Fang He Xiaolei Qi Honggang Wang | 2014 | Journal of Genetics and Genomics2014，41，12： | 10 |
| 2 | Effects of Y on the Microstructure, Mechanical and Bio-corrosion Properties of Mg-Zn-Ca Bulk Metallic Glass显示文摘The micro-alloying effects of Y on the microstructure, mechanical properties, and bio-corrosion behavior of Mg69-xZn27Ca4Yx(x= 0, 1, 2 at.%) alloys were investigated through X-ray diffraction, compressive tests,electrochemical treatments, and immersion tests. The Mg69Zn27Ca4 alloy was found to be absolutely amorphous, and its glass-forming ability decreased with the addition of Y. The Mg68Zn27Ca4Y1 alloy exhibited an ultrahigh compressive strength above 1010 MPa as well as high capacity for plastic strain above 3.1%.Electrochemical and immersion tests revealed that these Y-doped MgeZ neC a alloys had good bio-corrosion resistance in simulated body fluid(SBF) at 37℃. The results of the cytotoxicity test showed high cell viabilities for these alloys, which means good bio-compatibility. | Jingfeng Wang Yang Li Song Huang Yiyun Wei Xingfeng Xi Kaiyong Cai Fusheng Pan | 2014 | Journal of Materials Science & Technology2014，30，12： | 8 |
| 3 | Anatomical variation of infra-pyloric artery origination: A prospective multicenter observational study (IPA-Origin)显示文摘Objective: Infra-pyloric artery(IPA) is an important anatomical landmark in treatment of gastric cancer and is the key vessel for pylorus-preserving gastrectomy and subgroup of infra-pyloric lymph nodes. However, its anatomical variation is not thoroughly understood. Our study aimed to clarify the origination of the IPA.Methods: We did this prospective, multicenter, open-label, observational study at gastric surgery departments of34 hospitals in China. Gastric cancer patients aged 18 years or older and scheduled to undergo elective total or distal gastrectomy were assigned. During the surgery, IPA dissecting and exposing the origination point with photographs or video clips were required. The primary outcome was the origination of the IPA. Analysis of variance, χ~2 tests and Fisher's tests were used to analyze the differences between groups. The study is registered at Clinicaltrials.gov(No. NCT03071237).Results: Between May 8 and July 31, 2017, 429 patients were assigned for the study, and 419(97.7%) patients had the IPA dissected and recorded through photograph or video and were included in the primary outcome analysis. The median age was 62 years old, and 73.7% were male. Among the patients, 78.5% received laparoscopic surgery. Single IPA origination was identified in 398(95.0%) patients, including gastroduodenal artery(GDA) in154(36.8%) patients, anterior superior pancreaticoduodenal artery(ASPDA) in 130(31.0%) patients, and right gastroepiploic artery(RGEA) in 114(27.2%) patients. Fifteen(3.6%) patients were identified with multiple IPA and 6(1.4%) patients were identified as IPA absence. The differences in the distribution of surgical approach(P=0.003) and geographic area(P=0.030) were statistically significant. No difference was shown in sex, age,gastrectomy type, tumor location, and clinical T, N and M stage.Conclusions: Our study found that the IPA originates from GDA, ASPDA and RGEA in similar proportions.Laparoscopic surgery may be more helpful in dissection of the IPA than open surgery. | Rulin Miao Jianjun Qu Zhengrong Li Daguang Wang Jiang Yu Weidong Zang Yong Li Fenglin Liu Jian Zhang Wu Song Kai Ye Su Yan Wei Wang Shuangyi Ren Lu Zang Changqing Jing Li Zhang Kuan Wang Weihua Fu Lin Fan Bin Liang Gang Zhao Jun Cai Li Yang Jiaming Zhu Jun You Kun Yang Qingxing Huang Zhaojian Niu Ning Ning Xingfeng Qiu Gang Ji Feng Liang Hua Huang Chao Gao Fei Shan Shuangxi Li Yongning Jia Lianhai Zhang Xiangji Ying Yan Zhang Zhaode Bu Xiangqian Su Gang Zhao Ziyu Li Jiafu Ji | 2018 | Chinese Journal of Cancer Research2018，30，5： | 5 |
| 4 | Targeting PFKL with penfluridol inhibits glycolysis and suppresses esophageal cancer tumorigenesis in an AMPK/FOXO3a/BIM-dependent manner显示文摘As one of the hallmarks of cancer,metabolic reprogramming leads to cancer progression,and targeting glycolytic enzymes could be useful strategies for cancer therapy.By screening a small molecule library consisting of 1320 FDA-approved drugs,we found that penfluridol,an antipsychotic drug used to treat schizophrenia,could inhibit glycolysis and induce apoptosis in esophageal squamous cell carcinoma(ESCC).Gene profiling and Ingenuity Pathway Analysis suggested the important role of AMPK in action mechanism of penfluridol.By using drug affinity responsive target stability(DARTS)technology and proteomics,we identified phosphofructokinase,liver type(PFKL),a key enzyme in glycolysis,as a direct target of penfluridol.Penfluridol could not exhibit its anticancer property in PFKL-deficient cancer cells,illustrating that PFKL is essential for the bioactivity of penfluridol.High PFKL expression is correlated with advanced stages and poor survival of ESCC patients,and silencing of PFKL significantly suppressed tumor growth.Mechanistically,direct binding of penfluridol and PFKL inhibits glucose consumption,lactate and ATP production,leads to nuclear translocation of FOXO3a and subsequent transcriptional activation of BIM in an AMPK-dependent manner.Taken together,PFKL is a potential prognostic biomarker and therapeutic target in ESCC,and penfluridol may be a new therapeutic option for management of this lethal disease. | Cancan Zheng Xiaomei Yu Yiyao Liang Yidong Zhu Yan He Long Liao Dingkang Wang Yanming Yang Xingfeng Yin Ang Li Qingyu He Bin Li | 2022 | Acta Pharmaceutica Sinica B2022，12，3： | 4 |
| 5 | Metamaterial-enabled arbitrary on-chip spatial mode manipulation显示文摘On-chip spatial mode operation,represented as mode-division multiplexing(MDM),can support high-capacity data communications and promise superior performance in various systems and numerous applications from optical sensing to nonlinear and quantum optics.However,the scalability of state-of-the-art mode manipulation techniques is significantly hindered not only by the particular mode-order-oriented design strategy but also by the inherent limitations of possibly achievable mode orders.Recently,metamaterials capable of providing subwavelength-scale control of optical wavefronts have emerged as an attractive alternative to manipulate guided modes with compact footprints and broadband functionalities.Herein,we propose a universal yet efficient design framework based on the topological metamaterial building block(BB),enabling the excitation of arbitrary high-order spatial modes in silicon waveguides.By simply programming the layout of multiple fully etched dielectric metamaterial perturbations with predefined mathematical formulas,arbitrary high-order mode conversion and mode exchange can be simultaneously realized with uniform and competitive performance.The extraordinary scalability of the metamaterial BB frame is experimentally benchmarked by a record high-order mode operator up to the twentieth.As a proof of conceptual application,an 8-mode MDM data transmission of 28-GBaud 16-QAM optical signals is also verified with an aggregate data rate of 813 Gb/s(7%FEC).This user-friendly metamaterial BB concept marks a quintessential breakthrough for comprehensive manipulation of spatial light on-chip by breaking the long-standing shackles on the scalability,which may open up fascinating opportunities for complex photonic functionalities previously inaccessible. | Jinlong Xiang Zhiyuan Tao Xingfeng Li Yaotian Zhao Yu He Xuhan Guo Yikai Su | 2022 | Light(Science & Applications)2022，11，7： | 2 |
| 6 | Construction of an integrative linkage map and QTL mapping of grain yield-related traits using three related wheat RIL populations显示文摘 | Fa Cui Chunhua Zhao Anming Ding Jun Li Lin Wang Xingfeng Li Yinguang Bao Junming Li Honggang Wang | 2014 | Theoretical and Applied Genetics2014，，3： | 2 |
| 7 | Characterization on the formation of porosity and tensile properties prediction in die casting Mg alloys显示文摘The 3D visualization of the porosity in high-pressure die casting(HPDC)Mg alloys AZ91D and Mg4Ce2Al0.5Mn(EA42)was investigated by X-ray computed tomography.It was demonstrated that the volumetric porosity at the near-gate location for alloy EA42 was significantly higher than that far from the gate location.This difference resulted from the low valid time during intensified casting pressure conditions.Specimens of alloy EA42 exhibited a narrow pore distribution in the side view(~0.5 mm)compared to the wide distribution(~1.8 mm)of alloy AZ91D,which was mainly attributed to the formation mechanism of the defect band.The formation of microporosity in the defect band of alloy EA42 was inhibited because of the significant latent heat released by a large amount of the Al11Ce3phase segregated in the defect band during solidification.Additionally,an effective estimator(Z-Propagation)was introduced,which is proposed to predict the projected area fraction of the porosity(f)involved during tensile failure with better effectiveness compared with traditional methods based on the actual fractured surface.By coupling the Z-Propagation method with the critical local strain model,the logarithmic fracture strain and true fracture stress of the specimens were predicted within 3.03%and 1.65%of the absolute value of the average relative error(AARE),respectively. | Zixin Li Dejiang Li Wenke Zhou Bo Hu Xingfeng Zhao Jingya Wang Ming Qin Jiangkun Xu Xiaoqin Zeng | 2022 | Journal of Magnesium and Alloys2022，10，7： | 2 |
| 8 | Identification of a new potential Cd-hyperaccumulator Solanum photeinocarpum by soil seed bank-metal concentration gradient method显示文摘 | Xingfeng Zhang Hanping Xia Zhi’an Li Ping Zhuang Bo Gao | 2011 | Journal of Hazardous Materials2011，，1： | 2 |
| 9 | Plasticity of Sniffing Pattern and Neural Activity in the Olfactory Bulb of Behaving Mice During Odor Sampling,Anticipation,and Reward显示文摘The olfactory bulb(OB) is the first relay station in the olfactory system.In the OB,mitral/tufted cells(M/Ts),which are the main output neurons,play important roles in the processing and representation of odor information.Recent studies focusing on the function of M/Ts at the single-cell level in awake behaving mice have demonstrated that odor-evoked firing of single M/Ts displays transient/long-term plasticity during learning.Here,we tested whether the neural activity of M/Ts and sniffing patterns are dependent on anticipation and reward in awake behaving mice.We used an odor discrimination task combined with in vivo electrophysiological recordings in awake,head-fixed mice,and found that,while learning induced plasticity of spikes and beta oscillations during odor sampling,we also found plasticity of spikes,beta oscillation,sniffing pattern,and coherence between sniffing and theta oscillations during the periods of anticipation and/or reward.These results indicate that the activity of M/Ts plays important roles not only in odor representation but also in salience-related events such as anticipation and reward. | Penglai Liu Tiantian Cao Jinshan Xu Xingfeng Mao Dejuan Wang Anan Li | 2020 | Neuroscience Bulletin2020，36，6： | 2 |
| 10 | Synthesis of PS/Ag asymmetric hybrid particles via phase separation and self-assembly显示文摘This article presents a facile approach to preparation of polystyrene/silver(PS/Ag) asymmetric hybrid particles.In this method,polystyrene/polyglycidyl methacrylate(PS/PGMA)Janus particles were synthesized via internal phase separation triggered by evaporation of dichloromethane(DCM) from PS/PGMA/DCMin water emulsion droplets.Then,the Janus particles were aminated and sequentially carboxylated to obtain PS/PCMA-NHO_2 and PS/PCMA-COOH particles.Ag*self-assembled on the surface of PGMA hemisphere of the functionalized PS/PCMA particles by coordinating with amine/carboxyl.PS/Ag asymmetric hybrid particles with 7.29 wt%of Ag were obtained by reduction of Ag^+.Scanning electron microscopy,energy-dispersive X-ray spectroscopy and transmission electron microscopy results confirmed that Ag was asymmetrically distributed on the surface of polymer particles. | Xinlong Fan Qiuyu Zhang Hepeng Zhang Baoliang Zhang Chunmei Li Xiangjie Li Xingfeng Lei | 2013 | Particuology2013，11，6： | 1 |
| 11 | Genetic diver-sity and population structure of Salvia miltiorrhiza Bge in China revealed by ISSR and SRAP显示文摘 | SONG Zhenqiao LI Xingfeng WANG Honggang | 2010 | Genetica2010，138，2： | 1 |
| 12 | Evaluation of strategy for analyzing mouse liver plasma membrane proteome显示文摘Plasma membrane (PM) proteome is one of the major subproteomes present in the cell,and is very important in liver function. In the present work, C57 mouse liver PM was purified by density-gradient centrifugation. The purified PM was verified by electron microscope analysis and Western blotting. The results showed that the PM was enriched by more than 20-fold and the contamination of mitochondria was reduced by 2-fold compared with the homogenization fraction. Proteins were separated by 2DE and 1DE, trypsin-digested and submitted to ESI-Q-TOF and MALDI-TOF-TOF mass spectrometry or directly digested in solution and analyzed by LC-ESI ion trap mass spectrometry. In all, 547 non-redundant mouse liver PM proteins were identified, of which 34% contributed to plasma membrane or plasma membrane-related proteins. This study optimized and evaluated the HLPP plasma membrane proteome analysis method and made a systematic analysis on PM proteome. | CHEN Ping ZHANG LiJun LI XuanWen WANG XiE CAO Rui LIU Zhen XIONG JiXian PENG Xia WEI YingJuan YING XingFeng WANG XianChun LIANG SongPing | 2007 | Science China(Life Sciences)2007，50，6： | 1 |
| 13 | Purification,characterization, and modification of T lymphocyte-stimulating polysaccharide from spores of Ganoderma lucidum显示文摘 | BAO Xingfeng ZHEN Yun RUAN Li | 2002 | Chem Pharm Bull2002，50，5： | 1 |
| 14 | Potential of four forage grasses in remediation of Cd and Zn contaminated soils显示文摘 | Xingfeng Zhang Hanping Xia Zhian Li | | 0，，06： | 1 |
| 15 | Biotransformation of phenylpyruvic acid to phenyllactic acid by growing and resting cells of a Lactobacillus sp显示文摘 | Xingfeng Li Bo Jiang Beilei Pan | 2007 | Biotechnology Letters2007，29，4： | 1 |
| 16 | Iden-tification of a new potential Cd-hyper accumulator So-larium photeinocarpum by soil seed bank-metal concen-tration gradient method显示文摘 | Zhang Xingfeng Xia Hanping Li Zhi an | 2011 | Journal of Hazardous Ma-terials2011，189，12： | 1 |
| 17 | Molecular cytogenetic characterization of a novel wheat-Thinopyrum intermedium introgression line tolerant to phosphorus deficiency显示文摘Thinopyrum intermedium has been used as a resource for improving resistance to biotic and abiotic stresses and yield potential in common wheat. Wheat line SN304 was derived from a cross between common wheat cultivar Yannong 15 and Th. intermedium. Genomic in situ hybridization(GISH) produced no hybridization signal in SN304 using Th. intermedium genomic DNA as a probe, but fluorescence in situ hybridization(FISH) using oligonucleotides AFA-3, AFA-4, pAs1-1, pAs1-3, pAs1-4, pAs1-6, pSc119.2-1,and(GAA)10 as probes detected hybridization signals on chromosomes 2 A, 7 A, 2 B, 3 B, 6 B, and 7 B in SN304 that differed from Yannong 15. Results of specific markers also indicated that there were Th. intermedium chromatin introgressions on different chromosomes in SN304. In a hydroponic culture experiment, SN304 not only produced more biomass and higher stem and leaf dry weight but also accumulated more phosphorus than Yannong 15 under phosphorus-deficiency stress. Moreover, SN304 produced a lower pH and released more organic acids, especially oxalic acid, than Yannong 15, which suggests that SN304 exudates enabled more absorbance of P than Yannong 15 under comparable conditions.The results indicate that SN304 is a wheat-Th. intermedium introgression line with tolerance to phosphorus-deficiency stress. | Xia Zhang Caihong Cui Yinguang Bao Honggang Wang Xingfeng Li | 2021 | The Crop Journal2021，9，4： | 1 |
| 18 | Ultracompact topological photonic switch based on valley-vortex-enhanced high-efficiency phases shift显示文摘Topologically protected edge states based on valley photonic crystals(VPCs)have been widely studied,from theoretical verifcation to technical applications.However,research on integrated tuneable topological devices is still lacking.Here,we study the phase-shifting theory of topological edge modes based on a VPC structure.Benefiting from the phase vortex formed by the VPC structure,the optical path of the topological edge mode in the propagation direction is approximately two-fold that of the conventional optical mode in a strip waveguide.In experiments,we show a 1.57-fold improvement inπ-phase tuning efficiency.By leveraging the highefficiency phase-shifting properties and the sharp-turn features of the topological waveguide,we demonstrate an ultracompact 1×2 thermo-optic topological switch(TOTS)operating at telecommunication wavelengths.A switching power of 18.2 mW is needed with an ultracompact device footprint of 25.66×28.3μm in the wavelength range of 1530-1582 nm.To the best of our knowledge,this topological photonic switch is the smallest switch of any dielectric or semiconductor 1×2/2×2 broadband optical switches,including thermo-optic and electro-optic switches.In addition,a high-speed transmission experiment employing the proposed TOTS is carried out to demonstrate the robust transmission of high-speed data.Our work reveals the phase shifting mechanism of valley edge modes,which may enable diverse topological functional devices in many fields,such as optical communications,nanophotonics,and quantum information processing. | Hongwei Wang Gujing Tang Yu He Zhen Wang Xingfeng Li Lu Sun Yong Zhang Luqi Yuan Jianwen Dong Yikai Su | 2022 | Light(Science & Applications)2022，11，11： | 1 |
| 19 | Initial research on the polarized reflectance of typical urban surface types measured by the Directional Polarimetric Camera显示文摘This paper retrieves the bidirectional polarization distribution functions (BPDFs) of the distinct urban cover in the Pearl River Delta (PRD) region employing the high spatial resolution of multi-angle polarized measurements made by the Directional Polarimetric Camera (DPC).The BPDF operational products of MICROPOL and POLDER measurements were used to validate the BPDF products of the DPC,with the results demonstrating that the BPDF product of the DPC measurements accurately expresses the surface polarized reflectance.The polarized reflectance of distinct surface types in the PRD region was studied using the DPC measurements.The results demonstrate that the polarized reflectances of different surface types differ and decrease as the normalized difference vegetation index increases.The polarized reflectance of a distinct surface type in the PRD region decreases with increasing scattering angle.The basic theory of investigating surface properties using multi-angle polarized measurements is proposed. | XIE DongHai GU XingFa CHENG TianHai YU Tao LI ZhengQiang CHEN XingFeng CHEN Hao GUO Jing | 2011 | Science China Earth Sciences2011，54，8： | 1 |
| 20 | Structural Features of an Immunostimulating and Antioxidant Acidic Polysaccharide from the Seeds of Cuscuta chinensis显示文摘 | Xingfeng Bao Zhan Wang Jinian Fang Xiaoyu Li | 2002 | Planta Med2002，，03： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员