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| 1 | Analysis of status and countermeasures of cancer incidence and mortality in China显示文摘Cancer is the leading cause of human deaths in the world and produces serious economic burdens. On September 12, 2018, the academic journal A Cancer Journal for Clinicians published an article about the latest statistics of cancers worldwide, which provided a status report on the global burden of 36 cancers in 185 countries worldwide. Cancer has also become a serious public health problem in China and caused more and more attention of the government and people in recent years. This review analyzes the incidence, mortality and prevalent trend of cancers in China, discusses the reasons behind this status, and reviews the potential countermeasures for cancer prevention and control in China. | Chunchun Wu Mengna Li Hanbing Meng Yukun Liu Weihong Niu Yao Zhou Ran Zhao Yumei Duan Zhaoyang Zeng Xiaoling Li Guiyuan Li Wei Xiong Ming Zhou | 2019 | Science China(Life Sciences)2019，62，5： | 175 |
| 2 | Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients显示文摘Pathogenic human coronavirus infections,such as severe acute respiratory syndrome CoV(SARS-CoV)and Middle East respiratory syndrome CoV(MERS-CoV),cause high morbidity and mortality[1,2].Recently,a severe pneumonia-associated respiratory syndrome caused by a new coronavirus(SARS-CoV-2)was reported in December 2019 in the city of Wuhan,Hubei province,China[3-5],which was also named as pneumonia-associated respiratory syndrome(PARS)[6]and can cause coronavirus disease 2019(COVID-19)to seriously endanger human health. | Yonggang Zhou Binqing Fu Xiaohu Zheng Dongsheng Wang Changcheng Zhao Yingjie Qi Rui Sun Zhigang Tian Xiaoling Xu Haiming Wei | 2020 | National Science Review2020，7，6： | 54 |
| 3 | Three-dimensional hydrodynamic and water quality model for TMDL development of Lake Fuxian,China显示文摘Lake Fuxian is the largest deep freshwater lake in China.Although its average water quality meets Class I of the China National Water Quality Standard(CNWQS),i.e.,GB3838-2002,monitoring data indicate that the water quality approaches the Class II threshold in some areas.Thus it is urgent to reduce the watershed load through the total maximum daily load(TMDL) program.A three-dimensional hydrodynamic and water quality model was developed for Lake Fuxian,simulating flow circulation and pollutant fate and transport.The model development process consists of several steps,including grid generation,initial and boundary condition configurations,and model calibration processes.The model accurately reproduced the observed water surface elevation,spatiotemporal variations in temperature,and total nitrogen(TN),total phosphorus(TP),and chemical oxygen demand(COD) concentrations,suggesting a reasonable numerical representation of the prototype system for further TMDL analyses.The TMDL was calculated using two interpretations of the water quality standards for Class I of the CNWQS based on the maximum instantaneous surface and annual average surface water concentrations.Analysis of the first scenario indicated that the TN,TP and COD loads should be reduced by 66%,68% and 57%,respectively.Water quality was the highest priority;however,local economic development and cost feasibility for load reduction can pose significant issues.In the second interpretation,the model results showed that,under the existing conditions,the average water quality meets the Class I standard and therefore load reduction is unnecessary.Future studies are needed to conduct risk and cost assessments for realistic decision-making. | Lei Zhao Xiaoling Zhang Yong Liu Bin He Xiang Zhu Rui Zou Yuanguan Zhu | 2012 | Journal of Environmental Sciences2012，24，8： | 25 |
| 4 | Changes of protein oxidation,lipid oxidation and lipolysis in Chinese dry sausage with different sodium chloride curing salt content显示文摘The effect of sodium chloride(NaCl)curing salt content on protein oxidation,lipid oxidation and lipolysis of Chinese dry sausage was investigated.Two groups Chinese dry sausages with 2%and 4%(m/m)salt content were studied.The degree of protein oxidation increased during the processes in two groups sausages,while the content of phospholipids decreased,neutral lipids and free fatty acids increased.The degree of protein oxidation,lipid oxidation and lipolysis in 4%NaCl content group was higher than those in 2%NaCl content group,while 4%NaCl content group has higher lipase activity.In conclusion,4%NaCl may facilitate the protein oxidation,lipid hydrolysis and oxidation in Chinese dry sausage,and the protein oxidation had strong correlation with lipid oxidation and lipolysis.The results could provide a basis for improving the technology of industrial production. | Bing Zhao Huimin Zhou Shunliang Zhang Xiaoqian Pan Su Li Ning Zhu Qianrong Wu Shouwei Wang Xiaoling Qiao Wenhua Chen | 2020 | Food Science and Human Wellness2020，9，4： | 22 |
| 5 | Progress of the key materials for organic solar cells显示文摘Organic solar cells have attracted academic and industrial interests due to the advantages like lightweight,flexibility and roll-to-roll fabrication.Nowadays,18%power conversion efficiency has been achieved in the state-of-the-art organic solar cells.The recent rapid progress in organic solar cells relies on the continuously emerging new materials and device fabrication technologies,and the deep understanding on film morphology,molecular packing and device physics.Donor and acceptor materials are the key materials for organic solar cells since they determine the device performance.The past 25 years have witnessed an odyssey in developing high-performance donors and acceptors.In this review,we focus on those star materials and milestone work,and introduce the molecular structure evolution of key materials.These key materials include homopolymer donors,D-A copolymer donors,A-D-A small molecular donors,fullerene acceptors and nonfullerene acceptors.At last,we outlook the challenges and very important directions in key materials development. | Yang Tong Zuo Xiao Xiaoyan Du Chuantian Zuo Yuelong Li Menglan Lv Yongbo Yuan Chenyi Yi Feng Hao Yong Hua Ting Lei Qianqian Lin Kuan Sun Dewei Zhao Chunhui Duan Xiangfeng Shao Wei Li Hin-Lap Yip Zhengguo Xiaol Bin Zhang Qingzhen Bian Yuanhang Cheng Shengjian Liu Ming Cheng Zhiwen Jin Shangfeng Yang Liming Ding | 2020 | Science China Chemistry2020，63，6： | 15 |
| 6 | Endoplasmic reticulum oxidoreductin 1α mediates hepatic endoplasmic reticulum stress in homocysteine-induced atherosclerosis显示文摘Endoplasmic 蜂窝胃(嗯) 应力作为不同病理学的过程的一个重要调节的人并且作为贡献导致的 homocysteine (Hcy ) 的机制正在出现 hepar 损害。然而,分子的事件导致 Hcy 嗯在在动脉粥样硬化背景下面的 hepar 的应力当前是未知的。Endoplasmic 蜂窝胃 oxidoreductin (ERO1 ) 1 在维持起一个关键作用嗯压力功能。在这研究,我们在 hepacytes 在 hyperhomocysteinemia 和 ERO1 的效果在 hepar 决定了 ERO1 的表示嗯应力面对 Hcy。HHcy 模型被在 apolipoprotein-E-deficient (ApoE-/-) 喂蛋氨酸食谱建立老鼠,和 hepatocytes 与 Hcy 的叶酸、不同的集中被孵化。我们的结果证明 Hcy 被触发嗯应力描绘了由一调整葡萄糖的蛋白质的增加的内容 78 (GRP78 ) ,蛋白质 kinase 象 RNA 一样嗯 kinase (津贴) ,激活抄写因素(ATF ) 6 并且 X 盒子有约束力的 protein-1 (XBP-1 ) 。在 HHcy 老鼠和对待 Hcy 的 hepatocytes 的 ERO1 表情在 ApoE-/- 组和控制 hepacytes 与那些相比被减少(P < 0.05 ) 分别地。有小介入的 RNA 的 ERO1 的表示显著地扩充了的敲门下面导致 Hcy 嗯应力。同时,表情嗯压力相关的因素包括 GRP78,津贴, ATF6 和 XBP-1,当 ERO1 基因在 hepacytes 是过去表示的时,显著地被减少。我们的结果建议 ERO1 可以涉及导致 Hcy 的 hepar 嗯 ERO1 表示的应力,和抑制能加速这进程。 | Xiaoling Yang Hua Xu Yinju Hao Li Zhao Xin Cai Jue Tian Minghao Zhang Xuebo Han Shengchao Ma Jun Cao Yideng Jiang | 2014 | Acta Biochimica et Biophysica Sinica2014，46，10： | 14 |
| 7 | Arginine, N-carbamylglutamate,and glutamine exert protective effects against oxidative stress in rat intestine显示文摘The objective of the current study is to evaluate the effects of dietary supplementation with arginine(ARG), N-carbamylglutamate(NCG), and glutamine(GLN) on rat intestinal morphology and antioxidant status under oxidative stress. Rats were fed for 30 d with one of the following iso-nitrogenous diets:basal diet(BD), BD plus 1% ARG, BD plus 0.1% NCG, and BD plus 1% GLN. On day 28, half of the rats fed BD were intraperitoneally injected with 12 mg/kg body weight of diquat(DT; i.e., the DT group) and the other half was intraperitoneally injected with sterile solution(i,e., the control group). The other diet groups were intraperitoneally injected with 12 mg/kg body weight of DT(i,e., DT + 1% GLN [DT + GLN],DT + 1% ARG [DT + ARG], and DT + 0.1% NCG [DT + NCG]). Rat jejunum samples obtained at 48 h after DT injection were analyzed. Results showed that DT significantly decreased catalase(CAT) activity and glutathione(GSH) content by 58.25% and 56.57%, respectively, and elevated malondialdehyde(MDA)content and crypt depth(CD) by 19.39% and 22.13%, respectively, in the jejunum(P < 0.05, relative to the control group). Compared with the DT group, the DT + GLN group exhibited significantly improved villus height(VH), villus width(VW), villus surface area(VSA), CD and total antioxidant capacity(T-AOC) activity(P < 0.05); the DT + ARG group exhibited significantly increased the ratio of VH to CD(H:D) and TAOC activity(P < 0.05); the DT + GLN, DT + ARG and DT + NCG groups exhibited significantly enhanced CAT activity and GSH content as well as decreased MDA content(P < 0.05). Moreover, VH, VW, VSA, CD and GSH content in the DT + GLN group were higher whereas MDA content was lower compared with the corresponding values observed in both the DT + ARG and the DT + NCG groups(P < 0.05). The H:D ratio in the DT + ARG group significantly increased compared with that in the DT + NCG and DT + GLN groups(P < 0.05). Collectively, this study suggested that dietary supplementation with 1% GLN, 0.1% NCG,and 1% ARG was effective in enhancing the antioxidant status and maintaining the morphological structure of rat jejunum under oxidative stress; of these supplements, 1% GLN exerted the greatest effects on mitigating oxidative stress. | Liang Xiao Wei Cao Guangmang Liu Tingting Fang Xianjian Wu Gang Jia Xiaoling Chen Hua Zhao Jing Wang Caimei Wu Jingyi Cai | 2016 | Animal Nutrition2016，，3： | 12 |
| 8 | Enhanced photocatalytic hydrogen evolution along with byproducts suppressing over Z-scheme CdxZn1-xS/Au/g-C3N4 photocatalysts under visible light显示文摘Inspired by natural photosynthesis, a new series of Z-scheme Cd_xZn_(1-x)S/Au/g-C_3N_4 photocatalysts were synthesized via depositing Au particles on g-C_3N_4, followed by anchoring CdxZn_(1-x)S solid solution on the pre-formed Au/g-C_3N_4 for photocatalytic hydrogen evolution. Their structure, morphology and optical property were investigated in detail. Photocatalytic activities of the developed photocatalysts for water splitting were evaluated under visible-light irradiation(k > 420 nm) using glucose as electron donor.The highest hydrogen evolution rate of 123 lmol g^(-1)h^(-1)is achieved by Cd_(0.8Z)n_(0.2)S/Au/g-C_3N_4, which is 52.2 and 8.63 times higher than that of Au/g-C_3N_4 and Cd S/Au/g-C_3N_4, respectively. The results of photoluminescence spectra, photoelectrochemical and time-resolved photoluminescence spectra indicate that the improved photocatalytic activities for Cd_xZn_(1-x)S/Au/g-C_3N_4 are due to the efficient separation of photogenerated carriers. In addition, it is noteworthy that the undesired byproducts CO and CO_2 are greatly reduced by introducing CdxZn_(1-x)S over Au/g-C_3N_4 surface. In the photocatalytic process, gluconic acid originated from the reaction of photogenerated hydroxyl radical with glucose plays a vital role on suppressing the formation of the gas byproducts. The present work will provide a new strategy to design Z-scheme photocatalysts with enhanced efficiency for water splitting along with suppressing the byproducts. | He Zhao Xiaoling Ding Bing Zhang Yingxuan Li Chuanyi Wang | 2017 | Science Bulletin2017，62，9： | 12 |
| 9 | Serum IgA,IgM,and IgG responses in COVID-19显示文摘Currently,detecting SARS-CoV-2 RNAs is a standard approach for COVID-19 diagnosis.However,there is an urgent need for reliable and rapid serological diagnostic methods to screen SARS-CoV-2-infected people including those who do not have overt symptoms.Most emerging studies described serological tests based on detection of SARS-CoV-2-specific IgM and IgG.1–4 Although detection of SARS-CoV-2-specific IgA in serum has been reported in few papers,5,6 analyses of IgA levels in a larger number of COVID-19 patients are still lacking. | Huan Ma Weihong Zeng Hongliang He Dan Zhao Dehua Jiang Peigen Zhou Linzhao Cheng Yajuan Li Xiaoling Ma Tengchuan Jin | 2020 | Cellular & Molecular Immunology2020，17，7： | 12 |
| 10 | Preparation of hexagonal ultrathin WO3 nano-ribbons and their electrochemical performance as an anode material in lithium ion batteries显示文摘多达几测微计的 subnanometer 厚度, 25 nm 宽度,和长度的六角形的 ultrathin WO 3nano 带子(HUWNR ) 被一个 solvothermal 方法准备。同样准备的 HUWNR 成长[001 ] 方向,和主要暴露的方面是(120 ) 水晶飞机。因为他们的唯一的结构, HUWNR 在锂离子电池作为阳极材料展出好电气化学的性能。这些唯一的材料可以在许多地里被使用,这被相信。 | Chao Lian Xiaoling Xiao Zheng Chen Yuxi Liu Enyue Zhao Dingsheng Wang Chen Chen Yadong Li | 2016 | Nano Research2016，9，2： | 12 |
| 11 | Recent developments in HVDC transmission systems to support renewable energy integration显示文摘The demands for massive renewable energy integration, passive network power supply, and global energy interconnection have all gradually increased, posing new challenges for high voltage direct current(HVDC) power transmission systems, including more complex topology and increased diversity of bipolar HVDC transmission. This study proposes that these two factors have led to new requirements for HVDC control strategies. Moreover, due to the diverse applications of HVDC transmission technology, each station in the system has different requirements. Furthermore, the topology of the AC-DC converter is being continuously developed, revealing a trend towards hybrid converter stations. | Zhou Li Ruopei Zhan Yazhou Li Yan He Jinming Hou Xiaoling Zhao Xiao-Ping Zhang | 2018 | Global Energy Interconnection2018，1，5： | 11 |
| 12 | Characteristics of ozone vertical profile observed in the boundary layer around Beijing in autumn显示文摘In the autumn of 2008,the vertical profiles of ozone and meteorological parameters in the low troposphere (0-1000 m) were observed at two sites around Beijing,specifically urban Nanjiao and rural Shangdianzi.At night and early morning,the lower troposphere divided into two stratified layers due to temperature inversion.Ozone in the lower layer showed a large gradient due to the titration of NO.Air flow from the southwest brought ozone-rich air to Beijing,and the ozone profiles were marked by a continuous increase in the residual layer at night.The accumulated ozone in the upper layer played an important role in the next day's surface peak ozone concentration,and caused a rapid increase in surface ozone in the morning.Wind direction shear and wind speed shear exhibited different influences on ozone profiles and resulted in different surface ozone concentrations in Beijing. | Zhiqiang Ma Xiaoling Zhang Jing Xu xiujuan Zhao Wei Meng | 2011 | Journal of Environmental Sciences2011，23，8： | 11 |
| 13 | Roles of dietary supplementation with arginine or N-carbamylglutamate in modulating the inflammation, antioxidant property, and m RNA expression of antioxidant-relative signaling molecules in the spleen of rats under oxidative stress显示文摘This study evaluated the effects of arginine(Arg) or N-carbamylglutamate(NCG) on inflammation, antioxidant property, and antioxidant-related gene expression in rat spleen under oxidative stress. A total of 52 rats were randomly distributed into 4 treatment groups with 13 replicates per group. Rats were fed a basal diet(BD) or BD supplemented with Arg or NCG for 30 days. On day 28, half of the BD-fed rats were intraperitoneally injected with sterile saline(control group), and the other half with 12 mg/kg body weight of diquat(DT; DT group). The other 2 diet groups were intraperitoneally injected with 12 mg/kg body weight of DT with either Arg(1%)(DT t Arg) or NCG(0.1%)(DT t NCG). Rat spleen samples were collected for analysis at 48 h after DT injection. Results showed that DT damaged the antioxidant defense in rats compared with the control group(P < 0.05). Compared with the DT group, the DT t Arg and DT t NCG groups manifested improved anti-hydroxyl radical, catalase, and total superoxide dismutase(T-SOD) activities, increased glutathione content(P < 0.05), and decreased malondialdehyde content(P < 0.05).Moreover, compared with the DT group, the DT t Arg and DT t NCG groups enhanced mRNA expression of superoxide dismutase(SOD), glutathione peroxidase 1(GPx1), glutathione reductase(GR), nuclear factor erythroid 2-related factor 2(Nrf2), Kelch-like ECH-associated protein 1(Keap-1), and mammalian target of rapamycin(m TOR)(P < 0.05). Both NCG and Arg significantly increased anti-inflammatory cytokine mRNA level but suppressed the pro-inflammatory cytokine mRNA expression under oxidative stress(P < 0.05). In summary, NCG and Arg effectively alleviated oxidative stress, improved the antioxidant capacity and regulated the antioxidant-related signaling molecular expression in rat spleen. N-carbamylglutamate and Arg reduced the inflammation in the spleen by mediating the gene expression of anti-inflammatory and pro-inflammatory cytokines and transforming growth factor-β(TGF-β). | Weiwei Mo Xianjian Wu Gang Jia Hua Zhao Xiaoling Chen Jiayong Tang Caimei Wu Jingyi Cai Gang Tian Jing Wang Gangmang Liu | 2018 | Animal Nutrition2018，，3： | 9 |
| 14 | Micro-Channel Heat Sink:A Review显示文摘The method to cool a high heat flux device is an important research direction for the heat exchanger design.Micro-channels are an eflfective heat exchange structure both for single-phase and two-phase flow.In this paper,the heat transfer correlations of single-phase,two-phase and nanofluid in a micro-channel are discussed and analyzed.The correlations of pressure drop for single-phase and two-phase fluids are also presented.Excluding the different working fluids used in the micro-channel,the diameter and aspect ratio,shape and structure,surface roughness,internal and external factor and layout of micro-channel pipe are considered to analyze their influence on the heat transfer performance and pressure drop.Micro-channel technology applications include industry,air-conditioning,solar energy systems,heat pipe technology and computer data center cooling.Compared to the conventional heat exchangers used in these fields,a micro-channel heat sink showed a much better heat transfer coefficient and low volume,indicating that it is a good choice and has huge potential for cooling application.Finally,existing problems and future scopes are described,and drawing up design standard,experimental and simulated methods for evaluating its performance are the urgent actions which need to be carried out.This review paper serves as guidance for researchers to design and predict the performance of micro-channel heat sinks. | ZHOU Jinzhi CAO Xiaoling ZHANG Nan YUAN Yanping ZHAO Xudong HARDY David | 2020 | Journal of Thermal Science2020，29，6： | 9 |
| 15 | Endovascular therapy for Acute ischemic Stroke Trial (EAST): study protocol for a prospective, multicentre control trial in China显示文摘Background and purpose:5 recent trials have shown the benefit of endovascular treatment for acute ischaemic stroke(AIS)due to large vessel occlusion of the anterior circulation.This study aims to evaluate the safety and efficacy of Solitaire thrombectomy in patients with moderate-to-severe stroke in the Chinese population,which has a high prevalence of intracranial atherosclerosis.Methods and analysis:This multicentre prospective control study will involve 17 stroke centres in China,and plans to recruit 150 patients in the intervention group,and 150 patients in the medical group,in which patients meet enrolment criteria but refuse intervention.Patients with AIS due to large vessel occlusion indicated for treatment with Solitaire stent retriever within 12 hours of symptom onset,and who meet the inclusion and exclusion criteria,will be enrolled in this study.The primary efficacy endpoint is functional independence as defined by a modified Rankin Scale(mRS)score≤2 at 90 days or by functional improvement as defined by mRS,using shift analysis.The procedural efficacy endpoint is arterial recanalisation of the occluded target vessel measured by a modified Thrombolysis in Cerebral Infarction(mTICI)score equal or superior to 2b right following the use of the study device.The primary safety endpoint is symptomatic intracranial haemorrhage(sICH)within 24±3 hours postprocedure.Ethics and dissemination:The protocol was approved by the Ethics Committee at the coordinating centre and by the local Institutional Review Board of each participating centre.Trial registration number:NCT02350283. | Zhongrong Miao Xiaochuan Huo Feng Gao Xiaoling Liao Chunjuan Wang Ya Peng Yibin Cao Shengli Chen Meng Zhang Changchun Jiang Xiaoxiang Peng Cunfeng Song Liping Wei Qiyi Zhu Zaiyu Guo Li Liu Hang Lin Hua Yang Wei Wu Hui Liang Anding Xu Kangning Chen Xingquan Zhao Yuesong Pan Hao Li Liping Liu Yilong Wang Yongjun Wang EAST investigators | 2016 | Stroke & Vascular Neurology2016，1，2： | 8 |
| 16 | Actively priming autophagic cell death with novel transferrin receptor-targeted nanomedicine for synergistic chemotherapy against breast cancer显示文摘Recently, considerable attention in the field of cancer therapy has been focused on the mammalian rapamycin target(m TOR), inhibition of which could result in autophagic cell death(ACD). Though novel combination chemotherapy of autophagy inducers with chemotherapeutic agents is extensively investigated, nanomedicine-based combination therapy for ACD remains in infancy. In attempt to actively trigger ACD for synergistic chemotherapy, here we incorporated autophagy inducer rapamycin(RAP) into 7 pep-modified PEG-DSPE polymer micelles(7 pep-M-RAP) to specifically target and efficiently priming ACD of MCF-7 human breast cancer cells with high expression of transferrin receptor(Tf R). Cytotoxic paclitaxel(PTX)-loaded micelle(7 pep-M-PTX) was regarded as chemotherapeutic drug model. We discovered that with superior intracellular uptake in vitro and more tumor accumulation of micelles in vivo, 7 pep-M-RAP exhibited excellent autophagy induction and synergistic antitumor efficacy with 7 pep-M-PTX. Mechanism study further revealed that 7 pep-M-RAP and 7 pep-MPTX used in combination provided enhanced efficacy through induction of both apoptosis-and mitochondria-associated autophagic cell death. Together, our findings suggested that the targeted excess autophagy may provide a rational strategy to improve therapeutic outcome of breast cancer, and simultaneous induction of ACD and apoptosis may be a promising anticancer modality. | Dong Mei Binlong Chen Bing He Haibin Liu Zhiqiang Lin Jialiang Lin Xiaoyan Zhang Ning Sun Libo Zhao Xiaoling Wang Qiang Zhang | 2019 | Acta Pharmaceutica Sinica B2019，9，5： | 8 |
| 17 | Mitosis-specific acetylation tunes Ran effector binding for chromosome segregation显示文摘在房间期间,分割要求忠诚有丝分裂的锭子汇编和染色体分离的基因信息的稳定的传播。运用了 GTPase 戏在有丝分裂的锭子汇编的一个关键角色。然而,在锭子的 Ran-GTP 的一个化学坡度的产生怎么被联合到有丝分裂的 translational 以后修正,从来没被描绘过。这里,我们解决了复杂结构与核苷酸版本因素 Mog1 跑了并且描出一个新奇有丝分裂特定的调整 acetylation 的 Ran-Mog1 相互作用在染色体分离期间。我们的指导结构的功能的分析表明那 Mog1 与 RCC1 竞争为以一种 GTP/GDP-dependent 方式变有约束力。生物化学的描述表明了那 Mog1 固定跑阻止 RCC1 有约束力、随后的 GTP 装载。令人惊讶地,跑了是 TIP60 的真正的底层,并且由 TIP60 的 Lys134 的 acetylation 解放 Mog1 从在有丝分裂期间变有约束力。重要地,这个得到 acetylation 的开关对 RCC1 变有约束力支持 Ran-GTP 的高水平,它为染色体排列是必要的。这些结果建立一以前 TIP60 由调节在提供 Ran-GTP 水平的 homeostatic 控制的规章的机制运用了的 uncharacterized 为在有丝分裂的染色体分离的受动器绑定。 | Xiaoling Bao Heng Liu Xing Liu Ke Ruan Yonshui Zhang Zhiyong Zhang Qi Hu Ying Liu Saima Akram Jiahai Zhang Qingguo Gong Wenwen wang Xiao Yuan Jian-Li Lingli Zhao Zhen Dou Ruijun Tian Xuebiao Yao Jihui Wu Yunyu Shi | 2018 | Journal of Molecular Cell Biology2018，10，1： | 8 |
| 18 | Atmospheric correction of HJ-1A/B CCD images over Chinese coastal waters using MODIS-Terra aerosol data显示文摘This paper demonstrates an atmospheric correction method to process HJ-1A/B CCD images over Chinese coastal waters with the aid of MODIS-Terra aerosol information.Based on the assumption of zero water-leaving radiance at the two near-infrared (NIR)bands or the shortwave infrared(SWIR)bands,the atmospheric aerosol optical depth(AOD)is firstly retrieved from MODIS-Terra with a simple extension of the NIR-SWIR combined atmospheric correction approach embedded in SeaDAS (SeaWiFS data analysis system).Then the'turbid'and'non-turbid'waters are separated by the turbid water index.Maximum probability of AOD at 551 nm band is derived based on the NIR information over'non-turbid'waters and FLAASH model is selected to do the atmospheric correction of the HJ-1A/B CCD imagery using the AOD values of highest probabilities as input.Similarly,according to the histogram of the AOD distribution at 551 nm band,the studied turbid water area is divided into several blocks and HJ-1A/B CCD imagery is corrected with the corresponding AOD values displayed with the highest frequency in each block.This method has been applied to several HJ-1A/B images over Chinese coastal waters and validated by synchronous in-situ data.The results have shown that this method is effective in the atmospheric correction process of HJ-1A/B CCD images for ocean color remote sensing study and application in the coastal waters. | TIAN LiQiao 1,LU JianZhong 1,CHEN XiaoLing 1,2,3,YU ZhiFeng 1,XIAO JingJing 1,QIU Feng 1 & ZHAO Xi 1 1 State Key Laboratory of Information Engineering in Surveying,Mapping and Remote Sensing,Wuhan University,Wuhan 430079,China 2Key Laboratory of Poyang Lake Wetland and Watershed Research,Ministry of Education,Jiangxi Normal University,Nanchang 330022,China 3 The Key Laboratory of Poyang Lake Environment and Resource Utilization,Ministry of Education,Nanchang University,Nanchang 330031,China | 2010 | Science China(Technological Sciences)2010，53，S1： | 8 |
| 19 | A green method to synthesize flowerlike Fe(OH)3 microspheres for enhanced adsorption performance toward organic and heavy metal pollutants显示文摘Dyestuffs and heavy metal ions in water are seriously harmful to the ecological environment and human health.Three-dimensional(3 D) flowerlike Fe(OH)_3 microspheres were synthesized through a green yet low-cost injection method,for the removal of organic dyes and heavy metal ions.The Fe(OH)_3 microspheres were characterized by thermal gravimetric analysis(TGA),Fourier transform infrared(FT-IR),and transmission electron microscopy(TEM) techniques.The adsorption kinetics of Congo Red(CR) on Fe(OH)_3 microspheres obeyed the pseudo-second-order model.Cr^(6+) and Pb^(2+) adsorption behaviors on Fe(OH)_3 microspheres followed the Langmuir isotherm model.The maximum adsorption capacities of the synthesized Fe(OH)_3 were 308,52.94,and 75.64 mg/g for CR,Cr^(6+),and Pb^(2+) respectively.The enhanced adsorption performance originated from its surface properties and large specific surface area of 250 m^2/g.The microspheres also have excellent adsorption stability and recyclability.Another merit of the Fe(OH)_3 material is that it also acts as a Fenton-like catalyst.These twin functionalities(both as adsorbent and Fenton-like catalyst) give the synthesized Fe(OH)_3 microspheres great potential in the field of water treatment. | Xiaole Zhao Yingehun Su Shubin Li Yajun Bi Xiaojun Han | 2018 | Journal of Environmental Sciences2018，30，11： | 7 |
| 20 | Differentiation of rat iPS cells and ES cells into granulosa cell-like cells in vitro显示文摘早熟的卵巢的失败(POF ) 是卵巢的滤泡的早熟的弄空在 40 岁前描绘的一个卵巢的缺点,代表女不孕的一个主要原因。干细胞为 POF 提供一个潜在的处理的可能性。在这研究,老鼠胚胎的干细胞(转换字符) 和导致的 pluripotent 干细胞(iPSCs ) 与 granulosa 房间(GC ) 是 co 有教养的区分到象 GC 一样房间。放射性免疫测定分析的 estradiol (E2 ) 的水平证明 co 有教养的老鼠 iPSCs 和转换字符的文化上层清液的 E2 集中以一种时间依赖者方式增加了,与有一个相反的趋势的 GC 组相比。刺激滤泡的荷尔蒙受体(FSHR ) 的表示被 immunostaining 证实。这些结果显示了那老鼠 iPSCs,转换字符有效地通过间接 cell-to-cell 接触被导致到象 GC 一样房间。实时聚合酶链反应被执行在 POF 分析标记基因的表示水平,包括 BMP15, FMR1, FSHR, INHA, AMH, NOBOX, FOXO3, EIF2B, FIGLA,和 GDF9。BMP15, FSHR, INHA, AMH, NOBOX,和 GDF9 基因在 iPSCs 和与与不是 co 有教养的房间比较的 GC co 有教养的转换字符是显著地起来调整的。因此,这里,我们表明了一个可得到的方法为 POF 的可能的房间治疗在 vitro 区分老鼠 iPSCs 和转换字符进象 GC 一样房间。 | Juan Zhang Hui Li Zhao Wu XiaoJun Tan Fengying Liu Xianghong Huang Xiaoling Fang | 2013 | Acta Biochimica et Biophysica Sinica2013，45，4： | 7 |
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