|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effects of sediment dredging on water quality and zooplankton community structure in a shallow of eutrophic lake显示文摘Effects of suction dredging on water quality and zooplankton community structure in a shallow of eutrophic lake,were evaluated.The results showed that a decreasing trend for levels of phosphorus,organic matter,total suspended solids,Chlorophyll a and Secchi transparency in the water column was found,while levels of water depth,electrical conductivity,total dissolved solids and NO 3--N concentration increased markedly post-dredging.The effects of dredging on dissolved oxygen,pH value and temperature were almost negligible.The zooplankton community structure responded rapidly to the environmental changes caused mainly by dredging.As a result,the abundance of rotifers decreased,while the density of zooplanktonic crustaceans increased markedly.The representative taxa were Brachionus angularis,B.budapestinensis,B.diversicornis,Synchaeta spp.and Neodiaptomus schmackeri.A distinct relationship between zooplankton taxa composition and their environment,unraveled by a redundancy analysis,indicating that the measured environment contributed to the variations in the zooplankton community structure to some extent.The first four synthetic environmental variables explained 51.7% of the taxonomic structure.Therefore,with the reduction of internal nutrient load and a shift in dominance by less eutrophic species,it inferred that dredging might be one of effective measures for environmental improvements of such lakes. | Shiyang Zhang Qiaohong Zhou Dong Xu Jidong Lin Shuiping Cheng Zhenbin Wu | 2010 | Journal of Environmental Sciences2010，22，2： | 41 |
| 2 | The prognostic and therapeutic implications of circulating tumor cell phenotype detection based on epithelial-mesenchymal transition markers in the first-line chemotherapy of HER2-negative metastatic breast cancer显示文摘Background:Epithelial-mesenchymal transition(EMT)is implicated in the metastatic process and presents a chal-lenge to epithelial cell adhesion molecule-based detection of circulating tumor cells(CTCs),which have been demon-strated to be a prognostic indicator in metastatic breast cancer.Although evidence has indicated that heterogeneity of CTCs based on EMT markers is associated with disease progression,no standard recommendations have been established for clinical practice.This study aimed to evaluate the prognostic significance of dynamic CTC detection based on EMT for metastatic breast cancer patients.Methods:We enrolled 108 human epidermal growth factor receptor 2-negative metastatic breast cancer patients from the prospective phase III CAMELLIA study and applied the CanPatrol CTC enrichment technique to identify CTC phenotypes(including epithelial CTCs,biphenotypic epithelial/mesenchymal CTCs,and mesenchymal CTCs)in peripheral blood samples.Receiver operating characteristic curve analyses of total CTC count and the proportion of mesenchymal CTCs for predicting the 1-year progression-free survival(PFS)rate were conducted to determine the optimal cut-off values,and Kaplan-Meier analysis and Cox proportional hazards regression analysis were performed to investigate the prognostic value of the cut-off values of both total CTC count and the proportion of mesenchymal CTCs in combination.Results:For predicting the 1-year PFS rate,the optimal cut-off value of total CTC count was 9.5(Area under the curve[AUC]=0.538,95%confidence interval[CI]=0.418-0.657),and that of the proportion of mesenchymal CTCs was 10.7%(AUC=0.581,95%CI=0.463-0.699).We used the two cut-off values in combination to forecast PFS in which the total CTC count was equaled to or exceeded 10/5 mL with the proportion of mesenchymal CTCs surpassed 10.7%.Patients who met the combined criteria had significantly shorter median PFS than did those who did not meet the criteria(6.2 vs.9.9 months,P=0.010).A nomogram was constructed based on the criteria and significant clinicopatho-logical characteristics with a C-index of 0.613(P=0.010).Conclusions: The criteria, which combine the total CTC count and the proportion of mesenchymal CTCs, may be used to monitor therapeutic resistance and predict prognosis in patients with metastatic breast cancer. | Xiuwen Guan Fei Ma Chunxiao Li Shiyang Wu Shangying Hu Jiefen Huang Xiaoying Sun Jiayu Wang Yang Luo Ruigang Cai Ying Fan Qiao Li Shanshan Chen Pin Zhang Qing Li Binghe Xu | 2019 | Cancer Communications2019，39，1： | 15 |
| 3 | Genetic Polymorphisms in the Precursor MicroRNA Flanking Region and Non-Small Cell Lung Cancer Survival显示文摘 | Hu, Zhibin Shu, Yongqian Chen, Yijiang Chen, Jiaping Dong, Jing Liu, Yao Pan, Shiyang Xu, Lin Xu, Jing Wang, Yi Dai , Juncheng Ma, Hongxia Jin, Guangfu Shen,Hongbing | 2011 | 南京医科大学学报(自然科学版)2011，31，6： | 8 |
| 4 | Study of Shaking Table Test on Dynamic Response Characteristics and Failure Mechanism of the Loess Slope显示文摘The natural loess that covers the ground surface has good stability due to its low water content.However,when violent earthquakes occur,the strong dynamic stress generated in the slope may induce landslide disasters with different sizes.In this paper,a large-scale shaking table model test is used to reveal the dynamic response and instability failure process of the loess slope.The test results show that different parts of the slope have different vibration characteristics and the first natural frequency in the model increases with the increase of the slope height.The response acceleration of different parts may change due to the coupling relationship between the spectral characteristics of input wave and the natural frequencies of different parts of slope,suggesting the characteristics of regional differential dynamic response.Under the condition of different dynamic response,stress state and boundary conditions of different parts of slope,a rapid microstructural damage,cumulative residual deformation evolution,and tension-shear coupling instability failure process may appear at the top of the slope with the strong dynamic response associated with the increase of dynamic loading intensity.The Sd values presented in this paper may reflect soil damage and slope instability and failure. | PU Xiaowu WANG Lanmin WANG Ping CHAI Shaofeng XU Shiyang | 2020 | Earthquake Research in China2020，34，1： | 3 |
| 5 | Metasurface-based subtractive color filter fabricated on a 12-inch glass wafer using a CMOS platform显示文摘Optical color filters are widely applied in many areas including display,imaging,sensing,holography,energy harvest,and measurement.Traditional dye-based color filters have drawbacks such as environmental hazards and instability under high temperature and ultraviolet radiation.With advances in nanotechnology,structural color filters,which are based on the interaction of light with designed nanostructures,are able to overcome the drawbacks.Also,it is possible to fabricate structural color filters using standard complementary metal-oxide-semiconductor(CMOS)fabrication facilities with low cost and high volume.In this work,metasurface-based subtractive color filters(SCFs)are demonstrated on 12-inch(300-mm)glass wafers using a CMOS-compatible fabrication process.In order to make the transmissive-type SCF on a transparent glass wafer,an in-house developed layer transfer process is used to solve the glass wafer handling issue in fabrication tools.Three different heights of embedded silicon nanopillars(110,170,and 230 nm)are found to support magnetic dipole resonances.With pillar height and pitch variation,SCFs with different displayed colors are achieved.Based on the resonance wavelength,the displayed color of the metasurface is verified within the red-yellow-blue color wheel.The simulation and measurement results are compared and discussed.The work provides an alternative design for high efficiency color filters on a CMOS-compatible platform,and paves the way towards mass-producible large-area metasurfaces. | ZHENGJI XU NANXI LI YUAN DONG YUAN HSING FU TING HU QIZE ZHONG YANYAN ZHOU DONGDONG Li SHIYANG ZHU NAVAB SINGH | 2021 | Photonics Research2021，9，1： | 3 |
| 6 | Collaborative assembly-mediated siRNA delivery for relieving inflammation-induced insulin resistance显示文摘Obesity plays a primary causative role in insulin resistance and hyperglycemia that contributes to type 2 diabetes.Excess lipid storage in the liver renders activation of the resident macrophages and chronic secretion of inflammatory mediators,therefore causing or aggravating insulin resistance.Herein,we develop collaborative assemblies using a“one-pot”synthesis method for macrophage-specific delivery of small interfering RNAs(siRNAs)that target the inflammatory proteins.Ternary nanocomplex(NC)composed of the siRNA molecule,a synthetic thiol-bearing methacrylated hyaluronic acid(sm-HA)and protamine forms through an electrostatic-driven physical assembly,which is chemically crosslinked to acquire the collaboratively assembled nanocapsule(cNC)concurrently.The obtained cNC displays significantly higher stability than NC.Functional moieties as flexible assembly units can be easily equipped on cNC for long circulation,active targeting,or controlled siRNA release.cNC-F decorated with folic acid,a macrophage-targeting ligand promotes the siRNA accumulation in the activated macrophages in the liver of the obese mouse model.cNC-F loaded with siRNA targeting inflammatory indicators efficiently control the macrophage inflammatory response by reducing the expression of the inflammatory proteins(>40%reduction)and ameliorating the insulin resistance symptoms of the obese mice. | Shiyang Shen Li Zhang Mengru Li Zhizi Feng Huixia Li Xiao Xu Shiqi Lin Ping Li Can Zhang Xiaojun Xu Ran Mo | 2020 | Nano Research2020，13，11： | 2 |
| 7 | Preparation and Endothelialization of Multi-level Vessel-like Network in Enzymated Gelatin Scaffolds显示文摘 | Guirong Dong Qin Lian Laixia Yang Wei Mao Shiyang Liu Chao Xu | 2018 | Journal of Bionic Engineering2018，15，4： | 2 |
| 8 | Identification of Cinobufagin and Resibufogenin as Inhibitors of Enterovirus 71 Infection显示文摘 | CHEN Jiawen XU Lin SUN Shiyang ZHANG Huafei MA Tonghui SU Weiheng JIANG Chunlai | 2014 | Chemical Research in Chinese Universities2014，30，6： | 1 |
| 9 | A novel liquidchip platform for simultaneous detection of 70 alleles of DNA somatic mutations on EGFR, KRAS, BRAF and PIK3CA from formalin-fixed and paraffin-embedded slides containing tumor tissue显示文摘 | Guoqiang Li Xiaodi Luo Jiaying He Zeyao Zhu Gang Yu Huijuan Qin Tao Zeng Zhiming Liu Shiyang Wu Jiasen Xu Lifen Ren-Heidenreich | 2011 | Clinical Chemistry and Laboratory Medicine2011，，2： | 1 |
| 10 | 基于上皮–间质转化标志物的循环肿瘤细胞表型检测对HER2阴性转移性乳腺癌一线化疗的预后意义显示文摘背景与目的上皮–间质转化(epithelia-mesenchymal,EMT)参与肿瘤细胞的转移,并且对基于上皮细胞黏附分子的循环肿瘤细胞(circulating tumor cells,CTCs)检测技术提出了挑战,CTCs已被证实是转移性乳腺癌的预后指标。虽然有证据表明基于EMT标志物的CTCs异质性与疾病进展相关,但在临床应用方面尚无统一的参考标准。本研究旨在评估基于EMT的动态CTCs检测对转移性乳腺癌患者的预后意义。方法我们从CAMELLIA III期前瞻性研究中招募了108例人表皮生长因子受体2阴性转移性乳腺癌患者,并应用CanPatrol CTC富集技术检测外周血中不同亚型的CTCs(包括上皮型CTCs、混合型上皮/间质CTCs和间质型CTCs)。应用1年无进展生存(progression-free survival,PFS)率作为界值分别寻找CTC总数和间质CTCs比例的受试者工作曲线来确定最佳阈值,并采用Kaplan-Meier分析和Cox比例风险回归分析验证综合考虑CTC总数和间质型CTCs比例制定的诊断标准的预后价值。结果CTC总数的最佳阈值为9.5[曲线下面积(area under the curve,AUC)=0.538,95%置信区间(confidence interval,CI=0.418–0.657)]及间质CTCs比例为10.7%(AUC=0.581,95%CI:0.463–0.699)作为预测1年PFS率的界值。我们采用CTC总数≥10/5 mL且间质CTCs比例>10.7%的联合标准预测PFS。符合联合标准的患者的中位PFS显著短于不符合标准的患者(6.2个月vs.9.9个月,P=0.010)。根据该标准和显著的临床病理学特征绘制列线图,C指数为0.613(P=0.010)。结论CTC总数和间质CTCs比例的联合标准可用于监测转移性乳腺癌患者的治疗耐药性和预测患者预后。 | Xiuwen Guan Fei Ma Chunxiao Li Shiyang Wu Shangying Hu Jiefen Huang Xiaoying Sun Jiayu Wang Yang Luo Ruigang Cai Ying Fan Qiao Li Shanshan Chen Pin Zhang Qing Li Binghe Xu | 2019 | 癌症2019，38，9： | 1 |
| 11 | A novel mutant-enriched liquidchip technology for the qualitative detection of somatic mutations in KRAS gene from both serum and tissue samples显示文摘 | Shiyang Wu Zeyao Zhu Jiaying He Xiaodi Luo Jiasen Xu Lifen Ren-Heidenreich | 2010 | Clinical Chemistry and Laboratory Medicine2010，，： | 1 |
| 12 | Study on the Influence of Ni Modifying on Phase Transformation and Photocatalytic Activity of TiO_2显示文摘The Ni-modified TiO2 was synthesized using two methods including co-precipitation(Ni doped TiO2, Ni-TiO2) and wet impregnation(Ni loaded TiO2, Ni/TiO2). The surface and bulk crystalline phases of Ni-modified TiO2 were investigated by using X-ray diffractometry(XRD), UV Raman spectroscopy, TEM, and SEM. It is observed that Ni doping can promote the phase transition and grain size growth of TiO2. Moreover, the propagation of the rutile phase from the bulk into the surface region of TiO2 is increased when the Ni doping amount reaches up to 3%. However, in Ni/TiO2, it is found out that the surface and bulk phase transformation of TiO2 can be inhibited after impregnation of 1% of Ni on the TiO2. Compared with the co-precipitation method, Ni species may be more enriched in the surface of the Ni/TiO2 sample upon adoption of the impregnation method, and the direct contact of anatase particles of TiO2 is avoided. As a consequence, the phase transition in the surface and bulk region of TiO2 can be effectively inhibited by Ni loading. Additionally, the activity of the photocatalytic degradation of RhB on the 3Ni-TiO2-600 ℃ sample is higher than that on the 3 Ni/TiO2-600 ℃ sample. The phase junction formed between anatase and rutile in the surface region of 3Ni-TiO2-600 ℃ may the main reason for its high photocatalytic activity. | Wang Yan Zhang Jing Liu Shiyang Yan Song Wu Weicheng Xu Qian Li Can | 2014 | China Petroleum Processing & Petrochemical Technology2014，16，3： | 1 |
| 13 | Enrichment and enumeration of circulating tumor cells by efficient depletion of leukocyte fractions显示文摘 | Shiyang Wu Zhiming Liu Suyan Liu Li Lin Weiwei Yang Jiasen Xu | 2014 | Clinical Chemistry and Laboratory Medicine2014，，： | 1 |
| 14 | Mo-based perpendicularly magnetized thin films with low damping for fast and low-power consumption magnetic memory显示文摘Perpendicular magnetic anisotropy-based magnetic tunnel junctions(p-MTJs) with low Gilbert damping constant(α) are of particular interest for fast and low-power consumption magnetic random-access memory(MRAM). However, obtaining a faster switching speed and lower power consumption is still a big challenge. Herein, we report a Mo-based perpendicular double free layer structure with a low Gilbert damping constant of 0.02 relative to W-based films, as measured by time-resolved magnetooptical Kerr effect equipment. To show the influence of different film structures on the Gilbert damping constant, we measured the Mo-based single free layer. Thereafter, we deposited the full stacks with the Mo-based double free layer and obtained a high tunneling magnetoresistance of 136.3% and high thermal stability. The results of high-resolution transmission electron microscopy(HR-TEM) and energy-dispersive X-ray spectroscopy(EDS) showed that the Mo-based films had better crystallinity,sharper interfaces, and weaker diffusion than the W-based films and thus produced a weaker external contribution of the Gilbert damping constant. As a result of the weak spin-orbit coupling in the Mo-based structure, the intrinsic contribution of the Gilbert damping constant was also weak, thereby leading to the small Gilbert damping constant of the Mo-based stacks. In addition, the macro-spin simulation results demonstrated that the magnetization switching by the spin transfer torque of the Mo-based MTJs was faster than that of the W-based MTJs. These findings help to understand the mechanism behind the good performance of Mo-based p-MTJ films and show the great promise of these structures in low-power consumption MRAM or other spintronic devices. | Houyi Cheng Boyu Zhang Yong Xu Shiyang Lu Yuxuan Yao Rui Xiao Kaihua Cao Yongshan Liu Zilu Wang Renyou Xu Danrong Xiong Yan Wang Helin Ma Sylvain Eimer Chao Zhao Weisheng Zhao | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，8： | 0 |
| 15 | The response law of far-field seismic ground motion of the Wenchuan earthquake and its damaging mechanism in the Loess Plateau显示文摘A series of housing collapses and other serious damage was caused by the 2008 Wenchuan M_(S)8.0 earthquake in the seismic intensity Ⅵ areas of the Loess Plateau, which is hundreds of kilometers away from the epicenter, and which showed a remarkable seismic intensity anomaly. The seismic disasters are closely related to the seismic response characteristics of the site, therefore, the systematic study of the far-field seismic response law of the Wenchuan earthquake in the Loess Plateau is of great significance to prevent the far-field disaster of great earthquake. In this paper, the seismic acceleration records of several bedrock stations and loess stations from the seismogenic fault of the Wenchuan earthquake to the Loess Plateau were collected, and the attenuation law of ground motion along the propagation path and the characteristics of seismic response on the loess site are studied,and the mechanism of amplification effect of ground motion is analyzed based on the dynamic feature parameters of the loess site obtained through the HVSR method. Taking a typical loess site of thick deposit as the prototype, a series of shaking table tests of dynamic response of loess site models with different thicknesses were carried out.Amplification effect, spectral characteristics of acceleration in model sites were analyzed under the action of a farfield seismic wave of the Wenchuan earthquake. The results show that seismic attenuation on the propagation path along the NE strike of the seismogenic fault to the Loess Plateau is slower than that in other directions, and the predominant period range of ground motion on bedrock site of the Loess Plateau presents broadband characteristics. Because the natural periods of loess sites with thick deposits are within the predominant period range of bedrock input wave, loess sites appear significant amplification effect of ground motion, the horizontal acceleration of ground motion exceeds 0.1 g, the seismic intensity reaches 7°. The thicker the loess deposit is, the more significant the change of spectral characteristics of ground motion on loess sites, and the narrower the predominant period range of ground motion becomes, and the closer it is to the natural period of loess sites.Therefore, for some old houses on thick loess sites, the poor seismic performance and strong seismic response eventually led to their collapses and damages because their natural periods are very close to the predominant period of ground motion of the Wenchuan earthquake on thick loess sites;For these damaged high-rise buildings,the resonance effect might be the main reason for their damages because their natural periods are included in the predominant period range of ground motion of the Wenchuan earthquake on thick loess sites.These research results would provide a basis for seismic disasters prediction and evaluation and seismic design of construction engineering in the Loess Plateau. | Xiaowu Pu Lanming Wang Ping Wang Xiufeng Tian Shiyang Xu Shaofeng Chai Haitao Guo | 2022 | Earthquake Research Advances2022，2，3： | 0 |
| 16 | Cultural Practices for Edible Roses in the Open Field in Tropical Areas显示文摘The edible rose was planted on trial in Hainan under the tropical oceanic climate environment according to its botanic characteristics and growth habit.A set of cultural practices suitable for the edible rose planted in Hainan was summarized,including land selection,land preparation,variety selection,planting requirements,field management,pruning,flowering regulation,and control of pests and diseases. | Yilei ZHANG Huiqiu XU Hailiang ZHANG Shiyang HONG Jingtian LI Taihao CHEN Jingpin LIANG Guangying ZHAO | 2018 | Agricultural Biotechnology2018，7，1： | 0 |
| 17 | Recent research progress of laser plasma interactions in Shenguang laser facilities显示文摘Wereport experimental research on laser plasma interaction(LPI)conducted in Shenguang laser facilities during the past ten years.The research generally consists of three phases:(1)developing platforms for LPI research in mm-scale plasma with limited drive energy,where both gasbag and gas-filled hohlraum targets are tested;(2)studying the effects of beam-smoothing techniques,such as continuous phase plate and polarization smoothing,on the suppression of LPI;and(3)exploring the factors affecting LPI in integrated implosion experiments,which include the laser intensity,gas-fill pressure,size of the laser-entrance hole,and interplay between different beam cones.Results obtained in each phase will be presented and discussed in detail. | Tao Gong Liang Hao Zhichao Li Dong Yang Sanwei Li Xin Li Liang Guo Shiyang Zou Yaoyuan Liu Xiaohua Jiang Xiaoshi Peng Tao Xu Xiangming Liu Yulong Li Chunyang Zheng Hongbo Cai Zhanjun Liu Jian Zheng Zhebin Wang Qi Li Ping Li Rui Zhang Ying Zhang Fang Wang Deen Wang Feng Wang Shenye Liu Jiamin Yang Shaoen Jiang Baohan Zhang Yongkun Ding | 2019 | Matter and Radiation at Extremes2019，4，5： | 0 |
| 18 | Demonstration of a manufacturable SOT-MRAM multiplexer array towards industrial applications显示文摘We have successfully demonstrated a 1 Kb spin-orbit torque(SOT)magnetic random-access memory(MRAM)multiplexer(MUX)array with remarkable performance.The 1 Kb MUX array exhibits an in-die function yield of over 99.6%.Additionally,it provides a sufficient readout window,with a TMR/RP_sigma%value of 21.4.Moreover,the SOT magnetic tunnel junctions(MTJs)in the array show write error rates as low as 10^(-6)without any ballooning effects or back-hopping behaviors,ensuring the write stability and reliability.This array achieves write operations in 20 ns and 1.2 V for an industrial-level temperature range from-40 to 125℃.Overall,the demonstrated array shows competitive specifications compared to the state-of-the-art works.Our work paves the way for the industrial-scale production of SOT-MRAM,moving this technology beyond R&D and towards widespread adoption. | Chuanpeng Jiang Jinhao Li Hongchao Zhang Shiyang Lu Pengbin Li Chao Wang Zhongkui Zhang Zhengyi Hou Xu Liu Jiagao Feng He Zhang Hui Jin Gefei Wang Hongxi Liu Kaihua Cao Zhaohao Wang Weisheng Zhao | 2023 | Journal of Semiconductors2023，44，12： | 0 |
| 19 | Identification of COL3A1 variants associated with sporadic thoracic aortic dissection: a case-control study显示文摘Thoracic aortic dissection(TAD)without familial clustering or syndromic features is known as sporadic TAD(STAD).So far,the genetic basis of STAD remains unknown.Whole exome sequencing was performed in 223 STAD patients and 414 healthy controls from the Chinese Han population(N=637).After population structure and genetic relationship and ancestry analyses,we used the optimal sequence kernel association test to identify the candidate genes or variants of STAD.We found that COL3A1 was significantly relevant to STAD(P=7.35×10^(−6))after 10000 times permutation test(P=2.49×10^(−3)).Moreover,another independent cohort,including 423 cases and 734 non-STAD subjects(N=1157),replicated our results(P=0.021).Further bioinformatics analysis showed that COL3A1 was highly expressed in dissected aortic tissues,and its expression was related to the extracellular matrix(ECM)pathway.Our study identified a profile of known heritable TAD genes in the Chinese STAD population and found that COL3A1 could increase the risk of STAD through the ECM pathway.We wanted to expand the knowledge of the genetic basis and pathology of STAD,which may further help in providing better genetic counseling to the patients. | Yanghui Chen Yang Sun Zongzhe Li Chenze Li Lei Xiao Jiaqi Dai Shiyang Li Hao Liu Dong Hu Dongyang Wu Senlin Hu Bo Yu Peng Chen Ping Xu Wei Kong Dao Wen Wang | 2021 | Frontiers of Medicine2021，15，3： | 0 |
| 20 | Relationship between circadian rhythm and brain cognitive functions显示文摘Circadian rhythms are considered a masterstroke of natural selection,which gradually increase the adaptability of species to the Earth’s rotation.Importantly,the nervous system plays a key role in allowing organisms to maintain circadian rhythmicity.Circadian rhythms affect multiple aspects of cognitive functions(mainly via arousal),particularly those needed for effort-intensive cognitive tasks,which require considerable top-down executive control.These include inhibitory control,working memory,task switching,and psychomotor vigilance.This mini review highlights the recent advances in cognitive functioning in the optical and multimodal neuroimaging fields;it discusses the processing of brain cognitive functions during the circadian rhythm phase and the effects of the circadian rhythm on the cognitive component of the brain and the brain circuit supporting cognition. | Shiyang XU Miriam AKIOMA Zhen YUAN | 2021 | Frontiers of Optoelectronics2021，14，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员