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| 1 | Effects of Service Condition on Rolling Contact Fatigue Failure Mechanism and Lifetime of Thermal Spray Coatings——A Review显示文摘The service condition determines the Rolling Contact Fatigue(RCF) failure mechanism and lifetime under ascertain material structure integrity parameter of thermal spray coating. The available literature on the RCF testing of thermal spray coatings under various condition services is considerable; it is generally difficult to synthesize all of the result to obtain a comprehensive understanding of the parameters which has a great effect on a thermal spray coating's resistance of RCF. The effects of service conditions(lubrication states, contact stresses, revolve speed, and slip ratio) on the changing of thermal spray coatings' contact fatigue lifetime is introduced systematically. The effects of different service condition on RCF failure mechanism of thermal spray coating from the change of material structure integrity are also summarized. Moreover, In order to enhance the RCF performance, the parameter optimal design formula of service condition and material structure integrity is proposed based on the effect of service condition on thermal spray coatings' contact fatigue lifetime and RCF failure mechanism. The shortage of available literature and the forecast focus in future researches are discussed based on available research. The explicit result of RCF lifetime law and parameter optimal design formula in term of lubrication states, contact stresses, revolve speed, and slip ratio, is significant to improve the RCF performance on the engineering application. | CUI Huawei CUI Xiufang WANG Haidou XING Zhiguo JIN Guo | 2015 | Chinese Journal of Mechanical Engineering2015,28,1: | 12 |
| 2 | Bevacizumab biosimilar LY01008 compared with bevacizumab(Avastin)as first-line treatment for Chinese patients with unresectable,metastatic,or recurrent non-squamous non-small-cell lung cancer:A multicenter,randomized,double-blinded,phase Ⅲ trial显示文摘Background:Previous studies have demonstrated the preclinical pharmacological and toxicological consistency,and clinical pharmacokinetic equivalence of bevacizumab biosimilar LY01008 with reference bevacizumab(Avastin).This randomized controlled trial aimed to compare the efficacy and safety of LY01008 with Avastin in first-line treatment of Chinese patients with advanced or recurrent non-squamous non-small cell lung cancer(NSCLC).Methods:StageⅢB-ⅣNSCLC patients with evaluable lesions,good physical status,and adequate organ functions from 67 centers across China were randomized in a ratio of 1:1 to receive LY01008 or Avastin 15 mg/kg intravenously in combination with paclitaxel/carboplatin(combined treatment)for 4-6 cycles,followed by maintenance monotherapy with LY01008 until disease progression,intolerable toxicity,or death.The primary endpoint was objective response rate(ORR)in accordance with Response Evaluation Criteria in Solid Tumors(RECIST)version 1.1 confirmed by independent radiological review committees(IRRC).Secondary endpoints included disease control rate(DCR),duration of response(DoR),progression-free survival(PFS),overall survival(OS),and safety.This study was registered in Clinical Trials.gov(NCT03533127).Results:Between December 15^(th),2017,and May 15^(th),2019,a total of 649 patients were randomized to the LY01008(n=324)or Avastin(n=325)group.As of September 25th,2019 for primary endpoint analysis,589 patients received ORR evaluation,with a median number of combined treatment cycles of 5(range 1-6)andmedian duration of treatment of 3.0(range 0.0-5.1)months.ORRof responseevaluable patients in the LY01008 and Avastin groups were 48.5% and 53.0%,respectively.The stratified ORR ratio was 0.91(90%CI 0.80-1.04,within the prespecified equivalence margin of 0.75-1.33).Up to May 15^(th),2020,with a median follow-up of 13.6(range 0.8-28.4)months,no notable differences in DCR,median DoR,median PFS,median OS,and 1-year OS rate were observed between the LY01008 and Avastin groups.There were no clinically meaningful differences in safety and immunogenicity across treatment groups.Conclusions:LY01008 demonstrated similarity to Avastin in terms of efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC.LY01008 combined with paclitaxel/carboplatin is expected to become a new treatment option for unresectable,metastatic,LY01008 and Avastin groups.There were no clinically meaningful differences in safety and immunogenicity across treatment groups.Conclusions:LY01008 demonstrated similarity to Avastin in terms of efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC.LY01008 combined with paclitaxel/carboplatin is expected to become a new treatment option for unresectable,metastatic,or recurrent non-squamous NSCLC patients in the first-line setting. | Yuankai Shi Kaijian Lei Yuming Jia Bingqiang Ni Zhiyong He Minghong Bi Xicheng Wang Jianhua Shi Ming Zhou Qian Sun Guolei Wang Dongji Chen Yongqian Shu Lianke Liu Zhongliang Guo Yong Liu Junquan Yang Ke Wang Ke Xiao LinWu Tienan Yi Debin Sun Mafei Kang Tianjiang Ma Yimin Mao Jinsheng Shi Tiegang Tang Yan Wang Puyuan Xing Dongqing Lv Wangjun Liao Zhiguo Luo Bin Wang Xiaohong Wu Xiaoli Zhu Shuhua Han Qisen Guo Rongyu Liu Zhiwei Lu Jianyong Zhang Jian Fang Changlu Hu Yinghua Ji Guolong Liu Hong Lu Dedong Wu Junhong Zhang Shuyang Zhu Zheng Liu Wensheng Qiu Feng Ye Yan Yu Yanqiu Zhao Qinhong Zheng Jun Chen Zhanyu Pan Yiping Zhang Wenjuan Lian Bo Jiang Bo Qiu Guojun Zhang Hua Zhang Yanju Chen Yuan Chen Hongbing Duan Manxiang Li Shengming Liu Lijun Ma Hongming Pan Xia Yuan Xueli Yuan Yulong Zheng Emei Gao Li Zhao Shumin Wang Can Wu | 2021 | Cancer Communications2021,41,9: | 5 |
| 3 | The Erosion Effect of Kapton Film in a Ground-based Atomic Oxygen Irradiation Simulator显示文摘In order to investigate the effect of space environmental factors on spacecraft materials, a ground-based simulation facility for space atomic oxygen(AO) irradiation was developed in our laboratory. Some Kapton film samples were subjected to AO beam generated by this facility. The Kapton films before and after AO exposure were analyzed comparatively using optical microscopy, scanning electronic microscopy, atomic force microscopy, high-precision microbalance, and X-ray photoelectron spectroscopy. The experimental results indicate that the transmittance of Kapton film will be reduced by AO irradiation notably, and its color deepens from pale yellow to brown. Surface roughness of the AO-treated sample is already increased obviously after AO irradiation for 5 hours, and exhibits a flannel-like appearance after 15 hours' exposure in AO beam. The imide rings and benzene rings in kapton molecule are partially decomposed, and some new bonds form during AO irradiation. The mass loss of kapton film increases linearly with the increase of AO fluence, which is resulted from the formation of volatile products, such as CO, CO2 and NOx. The breakage in structure and degradation in properties of AO-treated Kapton film can be attributed to the integrated effect ofimpaction and oxidization of AO beam. The test results agree well with the space flight experimental data. | 王海斗 MA Guozheng XU Binshi XING Zhiguo LI Guolu ZHANG Sen | 2014 | Journal of Wuhan University of Technology(Materials Science)2014,29,6: | 4 |
| 4 | Elastic Scattering of 7Be on Pb Target显示文摘 | Yang Yanyun Wang Jiansong Wang Qi Huang Meirong Ma Junbing Ma Peng Cao Xiguang Han Jianlong Bai Zhen Jin Shilong Hu Qiang Jin Lei Chen Jiangbo Zhang Xueying Chen Ruofu Hu Zhengguo Xu Shiwei Zhen Chuan Xu Zhiguo Xu Hushan Duan Liming Sun Zhiyu Chen Zhiqiang He Jianjun Li Songlin Lei Xiangguo Fu Fen Zhang Xueheng Yuan Xiaohua Du Chengming Yan Xinshuang Hu Jun Tang Shuwen Ye Ruiping Yang Kun Shi Fudong Zhang Wei Chen Ze Li Long Xu Xing Liu Longxiang Zhang Liyong Lin Qingyun Gou Boxing Xu Ge Zhou Xionghong Zhang Yuhu Xiao Guoqing | 2011 | IMP & HIRFL Annual Report2011,,1: | 4 |
| 5 | Pd-Ni nanoparticles supported on titanium oxide as effective catalysts for Suzuki-Miyaura coupling reactions显示文摘 | Dongxu Han Zhiguo Zhang Zongbi Bao Huabin Xing Qilong Ren | 2018 | Frontiers of Chemical Science and Engineering2018,12,1: | 3 |
| 6 | Comprehensive test stand for high-intensity cyclotron development显示文摘A comprehensive test stand for high-intensity cyclotron development,a 10 MeV 430 μA cyclotron,has been successfully constructed at China Institute of Atomic Energy (CIAE) for the experimental verification of the viability of a 100 MeV high-intensity cyclotron (CYCIAE-100) being constructed at CIAE.The verification includes the overall design technology,detail design and engineering technology for the crucial parts of the machine,e.g.main magnet and beam diagnostics.It will also pave the way for future enhancement of the beam intensity.The test stand consists of a H-ion source,axial injection system,central region,main magnet and coil,RF resonator,stripping extraction,and auxiliary systems,which include the RF power amplifier,high voltage and DC power supplies,electric apparatus,beam diagnostics,control,vacuum,water cooling,pneumatic system,and safety interlock.This paper presents the work regarding the design and sub-system development of the test sand,and the results of the beam commissioning of the machine. | ZHANG TianJue LI ZhenGuo CHU ChengJie XING JianSheng GUAN FengPing ZHONG JunQing JI Bin GE Tao YIN ZhiGuo HOU ShiGang PAN GaoFeng YAO HongJuan LU YinLong WANG ZhenHui WU LongCheng LIN Jun JIA XianLu WEI SuMin WEN LiPeng WANG Feng XIA Le CAI HongRu XIE HuaiDong CHEN RongFan ZHANG Yan ZHANG SuPing LIU GengShou ZOU Jian AN ShiZhong YANG JianJun BI YuanJie YANG Fang | 2011 | Chinese Science Bulletin2011,56,3: | 3 |
| 7 | Current management of chemotherapy-induced neutropenia in adults:key points and new challenges显示文摘Chemotherapy-induced neutropenia(CIN)is a potentially fatal and common complication in myelosuppressive chemotherapy.The timing and grade of CIN may play prognostic and predictive roles in cancer therapy.CIN is associated with older age,poor functional and nutritional status,the presence of significant comorbidities,the type of cancer,previous chemotherapy cycles,the stage of the disease,specific chemotherapy regimens,and combined therapies.There are many key points and new challenges in the management of CIN in adults including:(1)Genetic risk factors to evaluate the patient’s risk for CIN remain unclear.However,these risk factors urgently need to be identified.(2)Febrile neutropenia(FN)remains one of the most common reasons for oncological emergency.No consensus nomogram for FN risk assessment has been established.(3)Different assessment tools[e.g.,Multinational Association for Supportive Care in Cancer(MASCC),the Clinical Index of Stable Febrile Neutropenia(CISNE)score model,and other tools]have been suggested to help stratify the risk of complications in patients with FN.However,current tools have limitations.The CISNE score model is useful to support decision-making,especially for patients with stable FN.(4)There are still some challenges,including the benefits of granulocyte colony stimulating factor treatment and the optimal antibiotic regimen in emergency management of FN.In view of the current reports,our group discusses the key points,new challenges,and management of CIN. | Committee of Neoplastic Supportive-Care(CONS),China Anti-Cancer Association Committee of Clinical Chemotherapy,China Anti-Cancer Association Yi Ba Yuankai Shi Wenqi Jiang Jifeng Feng Ying Cheng Li Xiao Qingyuan Zhang Wensheng Qiu Binghe Xu Ruihua Xu Bo Shen Zhiguo Luo Xiaodong Xie Jianhua Chang Mengzhao Wang Yufu Li Yuerong Shuang Zuoxing Niu Bo Liu Jun Zhang Li Zhang Herui Yao Conghua Xie Huiqiang Huang Wangjun Liao Gongyan Chen Xiaotian Zhang Hanxiang An Yanhong Deng Ping Gong Jianping Xiong Qinghua Yao Xin An Cheng Chen Yanxia Shi Jialei Wang Xiaohua Wang Zhiqiang Wang Puyuan Xing Sheng Yang Chenfei Zhou | 2020 | Cancer Biology & Medicine2020,17,4: | 2 |
| 8 | Flavonoids of Rosa rugosa Thunb.inhibit tumor proliferation and metastasis in human hepatocellular carcinoma HepG2 cells显示文摘Rosa rugosa Thunb.is recognized as both medicine and edible in China.The article investigated the antitumor activity of rose flavonoids.Water-extracted rose flavonoids(RFW)and ethanol-extracted rose flavonoids(RFE)were achieved by extracting with distilled water and 70%ethanol,respectively.The effects of the two extracts on proliferation inhibition,apoptosis inducement and metastasis prevention of human HepG2 hepatocellular carcinoma cell lines were tested,via optical/fluorescence microscopy,MTT detection,Transwell assay,flow cytometry and Western blot,etc.The results indicated that rose flavonoids at low concentration(10-40μg/mL)had a better inhibitory effect on migration and invasion of HepG2 cells in a dose-dependent manner,while rose flavonoids at high concentration(80-160μg/mL)could induce apoptosis of HepG2 cells by up-regulating the expression of pro-apoptotic proteins p53 and Bax,and down-regulating the expression of anti-apoptotic proteins Bcl-2,leading to the functioning of caspase-3 and caspase-9.The effect of RFE at the same concentration was significantly better than that of RFW.Conclusion,this study found that rose flavonoids had a certain inhibitory effect on proliferation and metastasis of human liver cancer cells HepG2,indicating the application of rose flavonoids in preventing and treating of liver cancer. | Zhiguo Zhang Meilin Wang Shu Xing Chen Zhang | 2022 | Food Science and Human Wellness2022,11,2: | 2 |
| 9 | Efficient conversion of crop stalk wastes into succinic acid production by Actinobacillus succinogenes显示文摘 | Qiang Li Maohua Yang Dan Wang Wangliang Li Yong Wu Yunjian Zhang Jianmin Xing Zhiguo Su | 2009 | Bioresource Technology2009,,9: | 1 |
| 10 | Microphysical Properties of Convective Clouds in Summer over the Tibetan Plateau from SNPP/VIIRS Satellite Data显示文摘The Tibetan Plateau (TP) plays an important role in formation and development of the East Asian atmospheric circulation, climate variability, and disastrous weathers in China. Among the many topics on TP meteorology, it is critical to understand the microphysical characteristics of clouds over the TP;however, observations of the cloud microphysics in this area are insufficient mainly due to sparse stations and limited cloud physical data. The Visible Infrared Imaging Radiometer Suite (VⅡRS), onboard the Suomi National Polar-orbiting Partnership (SNPP) satellite, has an improved imaging spectroradiometer with 17 channels of 750-m moderate resolution and 5 channels of 375-m image resolution. The high-resolution instrument has an advantage for observing the small or initial convective clouds. Based on the methodologies that we proposed before for retrieving cloud microphysical properties from SNPP, an automated mapping software package named Automatic Mapping of Convective Clouds (AMCC) has been developed at the scale of satellite swath. The properties of convective clouds are retrieved by AMCC and their values are averaged over 0.33°×0.33° grids based on the SNPP/VⅡRS satellite data over the TP during the summers of 2013-17. The results show that:(1) the temperature of lifting condensation level (TLCL) at Naqu meteorological station and the cloud base temperature (Tb) retrieved from VⅡRS are linearly correlated, with a correlation coefficient of 0.87 and standard deviation (STD) of 3.0℃;(2) convective clouds over the TP have the following macro-and microphysical properties. First, the cloud base temperature (Tb) is about -5℃, the cloud base height above the ground (Hb) ranges between 1800 and 2200 m, and the cloud water content is low. Second, the cloud condensation nuclei concentration (NCCN) is between 200 and 400 mg-1 with 0.7% in maximum supersaturation (Smax);consequently, the condensation growth of water cloud droplet with less NCCN and higher Smax is fast. Third, because the precipitation initiation depth (D14) varies within 1500-2000 m and 500-1000 m at the Yarlung Zangbo River basin and southern Tibet, respectively, the clouds over these areas are more prone to precipitation. Fourth, mean height of the cloud top above sea level (Htop) is between 10 and 13 km, but the cloud depth (Dcld) is rather small, which is about 5000 m in southern TP and gradually reduces to 2500 m in northern TP. Fifth, the glaciation temperature (Tg) ranges from -30℃ in central and southern TP to -25℃ in northern TP, which, combined with the warmer Tg and the Tb less than 0℃, leads to the domination of ice process in the clouds;(3) the macro-and microphysical properties of convective clouds over the TP explain why rainfall there is frequent and lasts over a short time with small amount and large rain drops. | Zhiguo YUE Xing YU Guihua LIU Jin DAI Yannian ZHU Xiaohong XU Ying HUI Chuang CHEN | 2019 | Journal of Meteorological Research2019,33,3: | 1 |
| 11 | Opening of Band Gap of Graphene with High Electronic Mobility by Codoping BN Pairs显示文摘Two-dimensional(2D)materials with a high density and low power consumption have become the most popular candidates for next-generation semiconductor electronic devices.As a prototype 2D material,graphene has attracted much attention owing to its stability and ultrahigh mobility.However,zero band gap of graphene leads to very low on-off ratios and thus limits its applications in electronic devices,such as transistors.Although some new 2D materials and doped graphene have nonzero band gaps,the electronic mobility is sacrificed.In this study,to open the band gap of graphene with high electronic mobility,the structure and property of BN-doped graphene were evaluated using first-principles calculations.The formation energies indicate that the six-membered BN rings doped graphene has the most favorable configuration.The band structures show that the band gaps can be opened by such type of doping.Also,the Dirac-cone-like band dispersion of graphene is mostly inhibited,ensuring high electronic mobility.Therefore,codoping BN into graphene might provide 2D materials with nonzero band gaps and high electronic mobility. | REN Xiangyang XIA Sha ZHANG Zhiguo MENG Xing YU Hongmei WU Qi ZHANG Wenyi LI Aiwu YANG Han | 2019 | Chemical Research in Chinese Universities2019,35,6: | 1 |
| 12 | Response surface regression analysis on FeCrBSi particle in-flight properties by plasma spray显示文摘这个工作由能在预言并且分析平均速度和温度被使用的血浆水花和构造模型在飞行中的粒子上讨论在二氩流动率,电压,和水花距离之间的交互效果。反应表面方法论的结果证明在粒子上的电压和水花距离之间的交互效果飞行中的性质重要。为给定的氩流动率,粒子速度和温度反应表面显然正在弯曲,并且一个僵绳点存在。随水花距离,在电压之间的交互效果和粒子上的氩流动率的增加,飞行中的性质逐渐地出现然后变弱。随电压的增加,在水花距离和氩流动之间的交互效果在飞行中的性质从出现到加强然后到变弱改变的粒子上评价。 | Runbo MA Lihong DONG Haidou WANG Shuying CHEN Zhiguo XING | 2016 | Frontiers of Mechanical Engineering2016,11,3: | 1 |
| 13 | Two New Coordination Complexes Based on 2,2'-H2biimidazole: Synthesis, Structure, Luminescent Property and Theoretical Calculation显示文摘Two new coordination complexes[Cd(L)2(1,2,3-HBTC)]·3H2O(1)and{[Zn(L)(1,2-BDC)]-H2O}n(2)were synthesized under hydrothermal conditions(1,2,3-H3 BTC=1,2,3-tricarboxybenzene,1,2-H2 BDC=1,2-dicarboxybenzene and L=2,2’-H2 biimidazole).1 crystallizes in monoclinic,space group P21/c with a=12.256(5),b=11.620(5),c=17.479(5)A,β=95.548(5)°,V=2477.6(16)A^3,Z=4,C21H22N8 O9 Cd,Mr=642.86,Dc=1.724 g/cm^3,F(000)=1296,μ(MoKa)=0.950 mm^-1,R=0.0546 and wR=0.1724.2 belongs to the monoclinic system,space group P21/c with a=7.408(4),b=20.743(10),c=10.194(5)A,β=95.648(6)°,V=1477.3(12)A^3,Z=4,C14H12N4 O5 Zn,Mr=381.65,Dc=1.716 g/cm3,F(000)=776,μ(MoKa)=1.698 mm^-1,R=0.0574 and wR=0.1632.The central Cd(Ⅱ)ion in 1 is coordinated with five atoms,forming a slightly distorted square-pyramidal geometry.The central Zn(Ⅱ)ion in 2 is four-coordinated by two nitrogen atoms from one L ligand and two oxygen atoms from two different 1,2-BDC anions.In addition,luminescent property of 1 has been investigated,and natural bond orbital(NBO)analysis of 2 has been calculated by the B3LYP/LANL2DZ method. | ZHANG Hua XU Tongtong XING Tianyi WANG Xueying ZUO Jiamei KONG Zhiguo | 2020 | Chinese Journal of Structural Chemistry2020,39,8: | 1 |
| 14 | Integrated bioprocess for high-efficiency production of succinic acid in an expanded-bed adsorption system显示文摘 | Qiang Li Dan Wang Guangyu Hu Jianmin Xing Zhiguo Su | 2011 | Biochemical Engineering Journal2011,,3: | 1 |
| 15 | Enhanced power conversion efficiency in iridium complexbased terpolymers for polymer solar cells显示文摘By introducing various low concentrations of Iridium complexes to the famous donor polymer of PTB7-Th backbone,new heavy metal containing terpolymers have been demonstrated.When blended with PC71BM,an obvious increase of power conversion efficiency(PCE)is obtained in 1 mol%Ir containing polymer for different photovoltaic devices either using Ca or PDIN as cathode interface layers.The impact of molecular weight on the photovoltaic performance has been particularly considered by using three batches of control polymer PTB7-Th to ensure a fair and more convincing comparison.At similar molecular weight conditions(Mn:~60 kg mol−1,M_(w):100-110 kg mol^(−1)),the 1 mol%Ir containing PTB7-ThIr1/PC71BM blends exhibits enhanced PCE to 9.19%compared with 7.92%of the control PTB7-Th.Through a combination of physical measurement,such as optoelectrical characterization,GIWAXS and pico-second time-resolved photoluminescence,the enhancement are contributed from comprehensive factors of higher hole mobility,less bimolecular recombination and more efficient slow process of charge separation. | Zhongyuan Xue Shifan Wang Jie Yang Yu Zhong Min Qian Cheng Li Zhiguo Zhang Guichuan Xing Sven Huettner Youtian Tao Yongfang Li Wei Huang | 2018 | npj Flexible Electronics2018,2,1: | 1 |
| 16 | Progress on Field Mapping System for 230 MeV Superconducting Cyclotron显示文摘Isochronism is a key factor to evaluate the performance of a cyclotron,which has to be calculated through field mapping.The field mapping range is from 0to 85cm in radial direction and 0to 360degree in azimuthal direction in the median plane.The maximum field is about4.0T.The required measurement precision | LI Ming LYU Yinlong ZHANG Tianjue CAO Lei XING Jiansheng WANG Chuan WANG Fei CUI Tao GUAN Leilei YIN Zhiguo YANG Guang | 2017 | Annual Report of China Institute of Atomic Energy2017,,1: | 1 |
| 17 | Two-Wave Mixing and Self-pumped Phase Conjugation with Photorefractive BaTiO_(3) at Near-Infrared Wavelengths显示文摘We studied the wavelength dependence of the exponential gain coefficient and response time of the two-wave mixing at near-infrared regime with an undoped BaTiO_(3).We also report a highly efficient self-pumpkd phase conjugation(SPPC).A 80%SPPC reflectivity at 741 nm was achieved. | ZHANG Zhiguo ZHU Yong KANG Jin WU Xing JIANG Qian FU Panming | 1994 | Chinese Physics Letters1994,11,3: | 0 |
| 18 | Tribo-informatics approaches in tribology research:A review显示文摘Tribology research mainly focuses on the friction,wear,and lubrication between interacting surfaces.With the continuous increase in the industrialization of human society,tribology research objects have become increasingly extensive.Tribology research methods have also gone through the stages of empirical science based on phenomena,theoretical science based on models,and computational science based on simulations.Tribology research has a strong engineering background.Owing to the intense coupling characteristics of tribology,tribological information includes subject information related to mathematics,physics,chemistry,materials,machinery,etc.Constantly emerging data and models are the basis for the development of tribology.The development of information technology has provided new and more efficient methods for generating,collecting,processing,and analyzing tribological data.As a result,the concept of'tribo-informatics(triboinformatics)'has been introduced.In this paper,guided by the framework of tribo-informatics,the application of tribo-informatics methods in tribology is reviewed.This article aims to provide helpful guidance for efficient and scientific tribology research using tribo-informatics approaches. | Nian YIN Zhiguo XING Ke HE Zhinan ZHANG | 2023 | Friction2023,11,1: | 0 |
| 19 | Binary Program Vulnerability Mining Based on Neural Network显示文摘Software security analysts typically only have access to the executable program and cannot directly access the source code of the program.This poses significant challenges to security analysis.While it is crucial to identify vulnerabilities in such non-source code programs,there exists a limited set of generalized tools due to the low versatility of current vulnerability mining methods.However,these tools suffer from some shortcomings.In terms of targeted fuzzing,the path searching for target points is not streamlined enough,and the completely random testing leads to an excessively large search space.Additionally,when it comes to code similarity analysis,there are issues with incomplete code feature extraction,which may result in information loss.In this paper,we propose a cross-platform and cross-architecture approach to exploit vulnerabilities using neural network obfuscation techniques.By leveraging the Angr framework,a deobfuscation technique is introduced,along with the adoption of a VEX-IR-based intermediate language conversion method.This combination allows for the unified handling of binary programs across various architectures,compilers,and compilation options.Subsequently,binary programs are processed to extract multi-level spatial features using a combination of a skip-gram model with self-attention mechanism and a bidirectional Long Short-Term Memory(LSTM)network.Finally,the graph embedding network is utilized to evaluate the similarity of program functionalities.Based on these similarity scores,a target function is determined,and symbolic execution is applied to solve the target function.The solved content serves as the initial seed for targeted fuzzing.The binary program is processed by using the de-obfuscation technique and intermediate language transformation method,and then the similarity of program functions is evaluated by using a graph embedding network,and symbolic execution is performed based on these similarity scores.This approach facilitates cross-architecture analysis of executable programs without their source codes and concurrently reduces the risk of symbolic execution path explosion. | Zhenhui Li Shuangping Xing Lin Yu Huiping Li Fan Zhou Guangqiang Yin Xikai Tang Zhiguo Wang | 2024 | Computers, Materials & Continua2024,78,2: | 0 |
| 20 | Mutual influence of copper and paraquat on their adsorption in soil显示文摘Paraquat and copper (Cu) are commonly used and detected in soil.Therefore,it is important to understand their mobility in the environment.In this study,the competitive effects of paraquat and Cu on their adsorption in five representative Chinese soils were investigated using batch adsorption equilibrium experiments and spectroscopic analysis.The results showed that the adsorption of paraquat in soil varied with soil type and was positively correlated with both soil cation exchange capacity and organic matter content.Paraquat exerted a more remarkable suppression effect on the adsorption of Cu than Cu on the adsorption of paraquat.In the presence of 0.12 and 0.19 mmol L-1paraquat,Cu adsorption decreased by 16%and 22%in Heilongjiang soil and by 24%and37%in Jiangxi soil,respectively.In the presence of 0.1 and 0.2 mmol L-1Cu,paraquat adsorption decreased by 4%and 8%in Heilongjiang soil and by15%and 19%in Jiangxi soil,respectively.Exchange selectivity involving symmetric cation (paraquat2+and Cu2+) exchange is the probable basis for the suppression effect.The ultraviolet-visible absorption experiments suggested that the formation of Cu-paraquat complexes was unlikely to happen in a solution or at the soil surface.Copper K-edge X-ray absorption spectroscopy indicated that Cu in soil may have some water as hydration layers as the nearest neighbors,and each Cu atom was coordinated with five oxygen atoms.These findings greatly improve our knowledge of the molecular-scale adsorption mechanisms of paraquat and Cu in soil and can be used to predict the behavior,transport,and fate of paraquat and Cu in agricultural soils. | Huanhua WANG Zhiguo PEI Guangcai CHEN Baoshan XING | 2023 | Pedosphere2023,33,6: | 0 |