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| 1 | Efficacy and safety of a novel anti-HER2 therapeutic antibody RC48 in patients with HER2-overexpressing,locally advanced or metastatic gastric or gastroesophageal junction cancer:a single-arm phase II study显示文摘Background:Current treatment options for human epidermal growth factor receptor 2(HER2)-overexpressing gastric cancer at third-line have shown limited clinical benefit.Further,there is no specific treatment for HER2 immunohistochemistry(IHC)2+and fluorescence in-situ hybridization-negative patients.Here,we report the efficacy and safety of a novel anti-HER2 antibody RC48 for patients with HER2-overexpressing,advanced gastric or gastroesophageal junction cancer.Methods:Patients with HER2-overexpressing(IHC 2+or 3+),locally advanced or metastatic gastric or gastroesophageal junction cancer who were under at least second-line therapy were eligible and received RC482.5 mg/kg alone every 2 weeks.The primary endpoint was the objective response rate(ORR)assessed by an independent review committee.Secondary endpoints included progressionfree survival(PFS),overall survival(OS),duration of response,time to progression,disease control rate,and safety.Results:Of 179 patients screened,125 were eligible and received RC48 treatment.The ORR was 24.8%(95%confidence interval[CI]:17.5%-33.3%).The median PFS and OS were 4.1 months(95%CI:3.7-4.9 months)and 7.9 months(95%CI:6.7-9.9 months),respectively.The most frequently reported adverse events were decreased white blood cell count(53.6%),asthenia(53.6%),hair loss(53.6%),decreased neutrophil count(52.0%),anemia(49.6%),and increased aspartate aminotransferase level(43.2%).Serious adverse events(SAEs)occurred in 45(36.0%)patients,and RC48-related SAEs were mainly decreased neutrophil count(3.2%).Seven patients had adverse events that led to death were not RC48-related.Conclusions:RC48 showed promising activity with manageable safety,suggesting potential application in patients with HER2-overexpressing,advanced gastric or gastroesophageal junction cancer who have previously received at least two lines of chemotherapy. | Zhi Peng Tianshu Liu Jia Wei Airong Wang Yifu He Liuzhong Yang Xizhi Zhang Nanfeng Fan Suxia Luo Zhen Li Kangsheng Gu Jianwei Lu Jianming Xu Qingxia Fan Ruihua Xu Liangming Zhang Enxiao Li Yuping Sun Guohua Yu Chunmei Bai Yong Liu Jiangzheng Zeng Jieer Ying Xinjun Liang Nong Xu Chao Gao Yongqian Shu Dong Ma Guanghai Dai Shengmian Li Ting Deng Yuehong Cui Jianmin Fang Yi Ba Lin Shen | 2021 | Cancer Communications2021，41，11： | 29 |
| 2 | Decision Tree Based Online Stability Assessment Scheme for Power Systems with Renewable Generations显示文摘The stochastic fluctuation of renewable energy resources has significant impact on the stability of the power system with renewable generations and results in change in stability.Therefore,it is necessary to track the changing stability of the power system with renewable generations,a task that can be performed online.This paper details the use of decision trees to predict multi-mode damping of power system integrating renewable generations with the help of wide-area measurements system(WAMS).Power systems with renewable source generation are complex with vast amounts of data being collected from WAMS.Decision trees(DTs)are employed as a means to handle vast quantities of wide-area information,which involves the mode damping information indicating the stability.A 16-generator,68-bus system with photovoltaic power generation and wind power generation is used as the test system.Remote signals obtained from phasor measurement units(PMUs)are employed as the input variables of DTs for predicting purposes.The simulation results demonstrate that the proposed predicting scheme is able to suggest the optimal course of action to remedy any near instability or unstable electromechanical oscillations even without prior knowledge of the varying output of the renewable source power. | Tong Wang Tianshu Bi Haifeng Wang Jizhen Liu | 2015 | CSEE Journal of Power and Energy Systems2015，1，2： | 21 |
| 3 | Biphasic insulin aspart 30 improved glycemic control in Chinese patients with type 2 diabetes poorly controlled on oral glucose-lowering drugs: a subgroup analysis of the A1chieve study显示文摘 | Chen Liming Xing Xiaoyan Lei Minxiang Liu Jie Shi Yongquan Li Pengqiu Qin Guijun Li Chengjiang Li Yukun Wang Qing Gao Tianshu Hu Ling Wang Yangwei Yang Wenying | 2014 | Chinese Medical Journal2014，，2： | 19 |
| 4 | Application of next-generation sequencing technology to precision medicine in cancer: joint consensus of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology显示文摘Next-generation sequencing(NGS) technology is capable of sequencing millions or billions of DNA molecules simultaneously.Therefore, it represents a promising tool for the analysis of molecular targets for the initial diagnosis of disease, monitoring of disease progression, and identifying the mechanism of drug resistance. On behalf of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology(CSCO) and the China Actionable Genome Consortium(CAGC), the present expert group hereby proposes advisory guidelines on clinical applications of NGS technology for the analysis of cancer driver genes for precision cancer therapy. This group comprises an assembly of laboratory cancer geneticists, clinical oncologists, bioinformaticians,pathologists, and other professionals. After multiple rounds of discussions and revisions, the expert group has reached a preliminary consensus on the need of NGS in clinical diagnosis, its regulation, and compliance standards in clinical sample collection. Moreover, it has prepared NGS criteria, the sequencing standard operation procedure(SOP), data analysis, report, and NGS platform certification and validation. | Xuchao Zhang Zhiyong Liang Shengyue Wang Shun Lu Yong Song Ying Cheng Jianming Ying Weiping Liu Yingyong Hou Yangqiu Li Yi Liu Jun Hou Xiufeng Liu Jianyong Shao Yanhong Tai Zheng Wang Li Fu Hui Li Xiaojun Zhou Hua Bai Mengzhao Wang You Lu Jinji Yang Wenzhao Zhong Qing Zhou Xuening Yang Jie Wang Cheng Huang Xiaoqing Liu Xiaoyan Zhou Shirong Zhang Hongxia Tian Yu Chen Ruibao Ren Ning Liao Chunyan Wu Zhongzheng Zhu Hongming Pan Yanhong Gu Liwei Wang Yunpeng Liu Suzhan Zhang Tianshu Liu Gong Chen Zhimin Shao Binghe Xu Qingyuan Zhang Ruihua Xu Lin Shen Yilong Wu | 2019 | Cancer Biology & Medicine2019，16，1： | 14 |
| 5 | Effect of hydrophilic silica nanoparticles on hydrate formation: Insight from the experimental study显示文摘Invasion of drilling fluid into natural gas hydrate deposits during drilling might damage the reservoir,induce hydrate dissociation and then cause wellbore instability and distortion of the data from well logging. Adding nanoparticles into drilling fluid is an effective method in reducing the invasion of drilling fluid and enhancing borehole stability. However, the addition of nanoparticles might also introduce hydrate formation risk in borehole because they can act as the 'seeds' for hydrate nucleation. This paper presents an experimental study of the effect of hydrophilic silica nanoparticle on gas hydrate formation in a dynamic methane/liquid-water system. In the experiment, the ultrapure water with and without1.0 wt%–6.0 wt% concentrations of silica nanoparticles, grain sizes of 20 and 50 nm, were pressurized by methane gas under varied conditions of temperature and pressure. The induction time, the gas consumption, and the average rate of gas consumption in the system were measured and compared to those in ultrapure water. The results show that a concentration of 4.0 wt% hydrophilic SiO_2 particles with a grain size of 50 nm has a relatively strong inhibition effect on hydrate formation when the initial experimental condition is 5.0 °C and 5.0 MPa. Compared to ultrapure water, the hydrophilic nano-SiO_2 fluid increases the induction time for hydrate formation by 194% and decreases the amount and average rate of hydrate formation by 10% and 17%, respectively. This inhibition effect may be attributed to the hydrophilicity,amount and aggregation of silica nanoparticle according to the results of water activity and zeta potential measurements. Our work also elucidates hydrophilic, instead of hydrophobic, nanoparticles can be added to the drilling fluid to maintain wellbore stability and to protect the hydrate reservoir from drilling mud damage, because they exhibit certain degree of hydrate inhibition which can reduce the risk of hydrate reformation and aggregation during gas hydrate or deep water drilling if their concentration can be controlled properly. | Ren Wang Tianle Liu Fulong Ning Wenjia Ou Ling Zhang Zhen Wang Li Peng Jiaxin Sun Zhichao Liu Tianshu Li Huicui Sun Guosheng Jiang | 2019 | Journal of Energy Chemistry2019，28，3： | 12 |
| 6 | On the mechanism and control for the ultra-low frequency oscillation in NY Power Grid with large-scale hydropower显示文摘The power grid with large proportion of hydropower may engage the ultra-low frequency oscillation (ULFO),which threatening the operation of system.To the NY Power Grid system,whose dimension is over thousands,this paper reveals the cause of ULFO with the phase portrait method,i.e.,lies in the saturation of the different limits of the governor system of the generators,in other words,the occurrence of limit cycle is due to the non-smooth bifurcation.And furthermore,it proposes two methods to suppress ULFO with the philosophy of destroying the condition of non-smooth bifurcation.In detail,first,the phenomenon of ULFO in NY Power Grid,the damping characteristics and the limits in the governor system of the hydropower units are presented.Second,based on the non-smooth bifurcation theory,the mathematical basis of the oscillation in the non-smooth system caused by the saturation of limits is introduced.And then,the non-oscillation and oscillation dynamic of the system corresponding to without/with limits in the governor system are analyzed.Furthermore,it discusses the influence of the saturation of single limit on the characteristics of ULFO with the phase portraits.Moreover,the phase portraits of the ULFO under different faults is analyzed,and it shows that the limiting saturation occurs with a large enough disturbance.Thus,the ULFO is resulting from the negative damping of generation and the saturation of multiple limits under a large enough disturbance.In addition,according to the above mechanism,two strategies to suppress the ULFO,i.e.,the governor parameters tuning and the fault strength relief are designed.The simulation shows the effectiveness of proposed strategies. | Ancheng XUE Jiawei WANG Chao ZHENG Joe H.CHOW Tianshu BI | 2019 | Control Theory and Technology2019，17，3： | 11 |
| 7 | Understanding unusually high levels of peroxyacetyl nitrate(PAN) in winter in Urban Jinan,China显示文摘Peroxyacetyl nitrate(PAN), as a major secondary pollutant, has gained increasing worldwide attentions, but relevant studies in China are still quite limited. During winter of 2015 to summer of 2016, the ambient levels of PAN were measured continuously by an automatic gas chromatograph equipped with an electron capture detector(GC–ECD) analyzer at an urban site in Jinan(China), with related parameters including concentrations of O3, NO, NO_2, PM_(2.5), HONO,the photolysis rate constant of NO_2 and meteorological factors observed concurrently. The mean and maximum values of PAN concentration were(1.89 ± 1.42) and 9.61 ppbv respectively in winter, and(2.54 ± 1.44) and 13.47 ppbv respectively in summer. Unusually high levels of PAN were observed during severe haze episodes in winter, and the formation mechanisms of them were emphatically discussed. Study showed that high levels of PAN in winter were mainly caused by local accumulation and strong photochemical reactions during haze episodes, while mass transport played only a minor role. Accelerated photochemical reactions(compared to winter days without haze) during haze episodes were deduced by the higher concentrations but shorter lifetimes of PAN, which was further supported by the sufficient solar radiation in the photolysis band along with the high concentrations of precursors(NO_2, VOCs) and HONO during haze episodes. In addition, significant PAN accumulation during calm weather of haze episodes was verified by meteorological data. | Lu Liu Xinfeng Wang Jianmin Chen Likun Xue Wenxing Wang Liang Wen Dandan Li Tianshu Chen | 2018 | Journal of Environmental Sciences2018，30，9： | 10 |
| 8 | Damping computation of liquid sloshing with small amplitude in rigid container using FEM显示文摘一女性(有限元素方法) 基于在僵硬容器与小振幅抑制液体 sloshing 的评价方法被建议。sloshing 抑制被许多因素影响,他们中的一些是很复杂的。因此,这篇论文试图提供一个评价范围,而不是计算抑制的准确价值。这个方法将在墙,并且在污染免费表面考虑驱散,在内部。由于在免费表面的粘滞的抑制的复杂性,二个极端条件抑制被计算估计实际抑制的范围。一个反复的算法被设计解决一个特殊一般特征值问题。比较计算与试验性的结果结果,大多数试验性的结果在数字评价的范围以内,这被发现。因此,方法在估计在僵硬容器与小振幅抑制液体 sloshing 的范围是有效的。 | Wei Wang Junfeng Li Tianshu Wang | 2006 | Acta Mechanica Sinica2006，22，1： | 10 |
| 9 | Hydroisomerization performance of platinum supported on ZSM-22/ZSM-23 intergrowth zeolite catalyst显示文摘Hydroisomerization catalysts Pt/ZSM-22,Pt/ZSM-23,and Pt/ZSM-22/ZSM-23 were prepared by supporting Pt on ZSM-22,ZSM-23,and intergrowth zeolite ZSM-22/ZSM-23,respectively.The typical physicochemical properties of these catalysts were characterized by X-Ray Diffraction(XRD),N2 absorption-desorption,Pyridine-Fourier Transform Infrared(Py-FTIR),Transmission Electron Microscopy(TEM),X-Ray Fluorescence(XRF),Scanning Electron Microscopy(SEM) and NH3-Temperature Programmed Desorption(NH3-TPD),and the performance of these catalysts in n-dodecane hydroisomerization was evaluated in a continuous down-flow fixed bed with a stainless steel tubular reactor.The characterization results indicated that the intergrowth zeolite ZSM-22/ZSM-23 possessed the dual structure of ZSM-22 and ZSM-23,and the catalyst Pt/ZSM-22/ZSM-23 had similar pores and weak acidity to Pt/ZSM-22 and Pt/ZSM-23 catalysts.Moreover,Pt/ZSM-22/ZSM-23 catalyst showed a high selectivity in hydroisomerization of long chain n-alkanes to mono-branched isomers.The evaluation results for n-dodecane hydroisomerization indicated that the activity of Pt/ZSM-22/ZSM-23 was the lowest,while the hydroisomerization selectivity was the highest among the three catalysts.The maximum yield of i-dodecane product was 68.3% over Pt/ZSM-22/ZSM-23 at 320 oC. | Chi Kebin Zhao Zhen Tian Zhijian Hu Sheng Yan Lijun Li Tianshu Wang Bingchun Meng Xiangbin Gao Shanbin Tan Mingwei Liu Yanfeng | 2013 | Petroleum Science2013，10，2： | 8 |
| 10 | Strong ozone production at a rural site in the North China Plain: Mixed effects of urban plumes and biogenic emissions显示文摘Regional ozone(O_3) pollution has drawn increasing attention in China over the recent decade, but the contributions from urban pollution and biogenic emissions have not been clearly elucidated. To better understand the formation of the regional O_3 problem in the North China Plain(NCP), intensive field measurements of O_3 and related parameters were conducted at a rural site downwind of Ji'nan, the capital city of Shandong province, in the summer of 2013. Markedly severe O_3 pollution was recorded, with the O_3 mixing ratios exceeding the Chinese national ambient air quality standard on 28 days(a frequency of 78%) and with a maximum hourly value of 198 ppbv. Extensive regional transport of wellprocessed urban plumes to the site was identified. An observation-constrained chemical box model was deployed to evaluate in situ photochemical O_3 production on two episodes.The results show that the in situ formation accounted for approximately 46% of the observed O_3 accumulation, while the remainder(~54%) was contributed by regional transport of the O_3-laden urban plumes. The in situ ozone production was in a mixed controlled regime that reducing either NOx or VOCs would lead to a reduction of ozone formation. Biogenic VOCs played an important role in the local ozone formation. This study demonstrates the significant mixed effects of both anthropogenic pollution from urban zones and biogenic emission in rural areas on the regional O_3 pollution in the NCP region,and may have general applicability in facilitating the understanding of the formation of secondary pollution over China. | Ruihan Zong Xue Yang Liang Wen Caihong Xu Yanhong Zhu Tianshu Chen Lan Yao Liwei Wang Junmei Zhang Lingxiao Yang Xinfeng Wang Min Shao Tong Zhu Likun Xue Wenxing Wang | 2018 | Journal of Environmental Sciences2018，30，9： | 8 |
| 11 | The precise regulation of different COR genes by individual CBF transcription factors in Arabidopsis thaliana显示文摘The transcription factors CBF1/2/3 are reported to play a dominant role in the cold responsive network of Arabidopsis by directly regulating the expression levels of cold responsive(COR) genes.In this study,we obtained CRISPR/Cas9-mediated loss-of-function mutants of cbf1$3.Over 3,000 COR genes identified by RNA-seq analysis showed a slight but significant change in their expression levels in the mutants compared to the wildtype plants after being treated at 4 °C for 12 h.The C-repeat(CRT) motif(50-CCGAC-30) was enriched in promoters of genes that were up-regulated by CBF2 and CBF3 but not in promoters of genes up-regulated by CBF1.These data suggest that CBF2 and CBF3 play a more important role in directing the cold response by regulating different sets of downstream COR genes.More than 2/3 of COR genes were co-regulated by two or three CBFs and were involved mainly in cellular signal transduction and metabolic processes;less than 1/3 of the genes were regulated by one CBF,and those genes up-regulated were enriched in cold-related abiotic stress responses.Our results indicate that CBFs play an important role in the trade-off between cold tolerance and plant growth through the precise regulation of COR genes in the complicated transcriptional network. | Yihao Shi Jiaying Huang Tianshu Sun Xuefei Wang Chenqi Zhu Yuxi Ai Hongya Gu | 2017 | Journal of Integrative Plant Biology2017，59，2： | 7 |
| 12 | Sensors deployment optimization in multi-dimensional space based on improved particle swarm optimization algorithm显示文摘Sensors deployment optimization has become one of the most attractive fields in recent years. However, most of the previous work focused on the deployment problem in 2 D space.Compared to the traditional form, sensors deployment in multidimensional space has greater research significance and practical potential to satisfy the detecting needs in complex environment.Aiming at solving this issue, a multi-dimensional space sensor network model is established, and the radar system is selected as an example. Considering the possible working mode of the radar system(e.g., searching and tracking), two distinctive deployment models are proposed based on maximum coverage area and maximum target detection probability in the attack direction respectively. The latter one is usually ignored in the previous literature.For uncovering the optimal deployment of the sensor network, the particle swarm optimization(PSO) algorithm is improved using the proposed weights determination scheme, in which the linear decreasing, the pooling strategy and the cloud theory are combined for weights updating. Experimental results illustrate the effectiveness of the proposed method. | TANG Mingnan CHEN Shijun ZHENG Xuehe WANG Tianshu CAO Hui | 2018 | Journal of Systems Engineering and Electronics2018，29，5： | 6 |
| 13 | Comparison of mixing layer height inversion algorithms using lidar and a pollution case study in Baoding, China显示文摘Beijing–Tianjin–Hebei area is suffering from atmospheric pollution from a long time. The understanding of the air pollution mechanism is of great importance for officials to design strategies for the environmental governance. Mixing layer height(MLH) is a key factor influencing the diffusion of air pollutants. It plays an important role on the evolution of heavy pollution events. Light detection and ranging(lidar), is an effective remote-sensing tool, which can retrieve high spatial and temporal evolution process within mixing layer(ML), especially the variation of MLH. There are many methods to retrieve MLH, but each method has its own applicable limitations. The Mie-lidar data in Beijing was firstly used to compare three different algorithms which are widely used under different pollution levels.We find that the multi-layer structure near surface may cause errors in the detection of mixing layer. The MLH retrieved based on image edge detection was better than another two methods especially under heavy polluted episode. Then we applied this method to investigate the evolution of the mixing layer height during a pollution episode in December2016. MLH at Gucheng county showed the positive correlation with the concentration of particulate matters during the start of this pollution episode. The elevated pollution level in Gucheng was not associated with MLH's decrease, and the significantly increased particulate matters raised the boundary layer, which trapped the pollutants near the surface. | Xiangguang Ji Cheng Liu Zhouqing Xie Qihou Hu Yunsheng Dong Guangqiang Fan Tianshu Zhang Chengzhi Xing Zhuang Wang Zeeshan Javed Jianguo Liu | 2019 | Journal of Environmental Sciences2019，31，5： | 5 |
| 14 | Selective removal of heavy metal ions in aqueous solutions by sulfide-selector intercalated layered double hydroxide adsorbent显示文摘Remaining largely under-appreciated, a majority of metal ion sorbents are limited in their target selectivity. In this work, a 3D sulfide intercalated NiFe-layered double hydroxide (NFL-S) hierarchical sorbent has been synthesized for selective heavy metal removal. The intercalation of sulfurated groups in the interlayer of the layered double hydroxide (LDH) nanosheets endows NFL-S as a selective heavy metal ion filter;the selectivity of NFL-S for heavy metals is in the order of Pb^2+> Cu^2+≥ Zn^2+> Cd^2+> Mn^2+, and NFL-S has high kd values for Pb2+(~10^6 mL/g) and Cu2+(~10^5 mL/g). Scanning electron microscopy. X-ray photoelectron spectroscopy and powder X-ray diffraction were used to analyze the composition of the as-prepared nanoadsorbent. The selective adsorption behavior was systematically studied using batch experiments, and the performance was evaluated through kinetic and isotherm studies. Moreover, the adsorption mechanism of heavy metals by NFL-S through surface complexation was also investigated, which shows great potential for water decontamination. | Jing Wang Liang Zhang Tianshu Zhang Ting Du Tao Li Tianli Yue Zhonghong Li Jianlong Wang | 2019 | Journal of Materials Science & Technology2019，35，9： | 5 |
| 15 | Passive walker that can walk down steps:simulations and experiments显示文摘有直腿和圆脚的一个平面被动的走模型被讨论。这个模型能沿步走,两个都在有甚至步并且与随机的楼梯上走。模拟证明有惯性的小时刻的模型能遨游大高度步。加倍时期当在步之间的空间成长时,被观察了。这加倍时期被实验验证了,并且实验的结果与模拟是重合的。 | Ning Liu Junfeng Li Tianshu Wang | 2008 | Acta Mechanica Sinica2008，24，5： | 5 |
| 16 | Genomic profiling and the impact of MUC19 mutation in hepatoid adenocarcinoma of the stomach显示文摘Dear Editor,Hepatoid adenocarcinoma(HAC)is a rare pathological subtype of extrahepatic tumor,featured by hepatoid differentiation andα-fetoprotein(AFP)-production[1,2].Hepatoid adenocarcinoma of the stomach(HAS),accounting for 0.3%to 1.0%of all gastric cancers(GCs),has attracted increasing attention due to its high degree of malignancy[3].Compared with classic GC,HAS showed a higher rate of vascular invasion,lymph node metastasis,and liver metastasis,with only 9.0%survival rate at 5 years[4].Currently,there is no effective treatment for HAS,and little is known about its pathogenesis.Herein,we investigated the molecular features of HAS and identified potential therapeutic targets for HAS. | Mengxuan Zhu Erbao Chen Shan Yu Chen Xu Yiyi Yu Xin Cao Wei Li Pengfei Zhang Yan Wang Baofeng Lian Shuirong Zhang Yueting Qu Lujia Huang Weiwei Shi Yuehong Cui Li Qian Tianshu Liu | 2022 | Cancer Communications2022，42，10： | 3 |
| 17 | Coupling dynamic analysis of a liquid-filled spherical container subject to arbitrary excitation显示文摘Using spherical coordinates, the coupling nonlin- ear dynamic system of a liquid-filled spherical tank, which can be excited discretionarily, is deduced by the H-O variational principle, and the viscous damping is introduced via the liquid dissipation function. The kinetic equations of the coupling system are deduced by the relationship between the velocity of liquid particles and the disturbed liquid surface equation. Normal differential equations are obtained through the Galerkin method. An equivalent mechanical model is developed for liquid sloshing in a spherical tank subject to arbitrary excitation. The fixed and slosh masses, as well as the spring and damping constants, are determined in such a way as to satisfy the principle of equivalence. Numerical simulations illustrate the theoretical results in this paper as well. | Jing Lü Shimin Wang Tianshu Wang | 2012 | Acta Mechanica Sinica2012，28，4： | 3 |
| 18 | Observational Study on the Supercooled Fog Droplet Spectrum Distribution and Icing Accumulation Mechanism in Lushan, Southeast China显示文摘A fog monitor, hotplate total precipitation sensor, weather identifier and visibility sensor, ultrasonic wind speed meter,an icing gradient observation frame, and an automated weather station were involved in the observations at the Lushan Meteorological Bureau of Jiangxi Province, China. In this study, for the icing process under a cold surge from 20–25 January2016, the duration, frequency, and spectrum distribution of agglomerate fog were analyzed. The effects of rain, snow, and supercooled fog on icing growth were studied and the icing and meteorological conditions at two heights(10 m and 1.5 m)were compared. There were 218 agglomerate fogs in this icing process, of which agglomerate fogs with durations less than and greater than 10 min accounted for 91.3% and 8.7%, respectively. The average time interval was 10.3 min. The fog droplet number concentration for sizes 2–15 μm and 30–50 μm increased during rainfall, and that for 2–27 μm decreased during snowfall. Icing grew rapidly(1.3 mm h-1) in the freezing rain phase but slowly(0.1 mm h-1) during the dry snow phase. Intensive supercooled fog, lower temperatures and increased wind speed all favored icing growth during dry snow(0.5 mm h-1). There were significant differences in the thickness, duration, density, and growth mechanism of icing at the heights of 10 m and 1.5 m. Differences in temperature and wind speed between the two heights were the main reasons for the differences in icing conditions, which indicated that icing was strongly affected by height. | Tianshu WANG Shengjie NIU Jingjing Lü Yue ZHOU | 2019 | Advances in Atmospheric Sciences2019，36，1： | 3 |
| 19 | A trigonometric interval method for dynamic response analysis of uncertain nonlinear systems显示文摘This paper proposes a new non-intrusive trigonometric polynomial approximation interval method for the dynamic response analysis of nonlinear systems with uncertain-but-bounded parameters and/or initial conditions.This method provides tighter solution ranges compared to the existing approximation interval methods.We consider trigonometric approximation polynomials of three types:both cosine and sine functions,the sine function,and the cosine function.Thus,special interval arithmetic for trigonometric function without overestimation can be used to obtain interval results.The interval method using trigonometric approximation polynomials with a cosine functional form exhibits better performance than the existing Taylor interval method and Chebyshev interval method.Finally,two typical numerical examples with nonlinearity are applied to demonstrate the effectiveness of the proposed method. | LIU ZhuangZhuang WANG TianShu LI JunFeng | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，4： | 3 |
| 20 | Observation and optimization of 2 μm mode‐locked pulses in all‐fiber net anomalous dispersion laser cavity显示文摘We integrally demonstrate 2μm mode-locked pulses performances in all-fiber net anomalous dispersion cavity.Stable mode-locking operations with the center wavelength around 1950–1980 nm can be achieved by using the nonlinear polarization rotation structure and properly designing the dispersion management component.Conventional soliton is firstly obtained with a total anomalous dispersion cavity.Due to the contribution of commercial ultra-high numerical aperture fibers,net dispersion is reduced to-0.077 ps2.So that stretched pulse with 19.4 nm optical bandwidth is obtained and the de-chirped pulse-width can reach 312 fs using extra-cavity compression.Under pump power greater than 890 mW,stretched pulse can evolve into noise-like pulse with 41.3 nm bandwidth.The envelope and peak of such broadband pulse can be compressed with up to 2.2 ps and 145 fs,respectively.The single pulse energy of largely chirped stretched and noise-like pulse can reach 1.785 nJ and 1.53 nJ,respectively.Furthermore,extra-cavity compression can also contribute to a significant increase of peak power. | Wanzhuo Ma Desheng Zhao Runmin Liu Tianshu Wang Quan Yuan Hao Xiong Haiying Ji Huilin Jiang | 2020 | Opto-Electronic Advances2020，3，11： | 2 |
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