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| 1 | 卒中相关性肺炎的诊断卒中肺炎共识小组的推荐意见显示文摘背景和目的下呼吸道感染常并发于卒中并对转归造成不利影响。对于并发于卒中的下呼吸道感染性疾病,目前尚无公认的专业术语或诊断金标准,这导致临床诊疗和研究受到影响。本共识旨在提出急性卒中并发下呼吸道感染的标准化术语和可操作性诊断标准。方法对多个文献数据库进行系统检索,经过证据回顾和2轮讨论,最后于2014年9月在英国曼彻斯特召开共识会议,经75%以上共识小组成员达成一致意见后形成共识。结果达成的共识如下:(1)推荐使用卒中相关性肺炎(stroke-associated pneumonia, SAP )作为卒中发病后7 d内发生的下呼吸道感染性疾病的专业术语。(2)提议对 SAP 使用经过改良的美国疾病控制预防中心(Centers for Disease Control and Prevention, CDC)诊断标准:①很可能的 SAP:符合 CDC 诊断标准,但复查或动态监测胸部 X 片仍缺乏典型改变;②确诊的 SAP:符合 CDC 诊断标准,且胸部 X 片有典型改变。(3)关于白细胞计数或 C反应蛋白在 SAP 诊断中的作用证据有限。(4)其他生物学标记物(如降钙素原)的证据不足。结论提议根据 CDC 诊断标准对 SAP 的术语和诊断制定可操作性的共识标准,需要在卒中患者中进行前瞻性研究来确定其信度、效度以及对医生行为(包括抗生素选择)和临床转归的影响。 | Craig J. Smith Amit K Kishore Andy Vail Angel Chamorro Javier Garau Stephen J. Hopkins Mario Di Napoli Lalit Kalra Peter Langhorne Joan Montaner Christine Roffe Anthony G. Rudd Pippa J. TyrreU Diederik van de Peek Mark Woodhead Andreas Meisel 范琳琳 宿英英 | 2016 | 国际脑血管病杂志2016，24，2： | 17 |
| 2 | Radiofrequency ablation for early oesophageal squamous neoplasia:Outcomes form United Kingdom registry显示文摘AIM:To report outcomes on patients undergoing radiofrequency ablation(RFA)for early oesophageal squamous neoplasia from a National Registry.METHODS:A Prospective cohort study from 8 tertiary referral centres in the United Kingdom.Patients with squamous high grade dysplasia(HGD)and early squamous cell carcinoma(ESCC)confined to the mucosa were treated.Visible lesions were removed by endoscopic mucosal resection(EMR)before RFA.Following initial RFA treatment,patients were followed up 3monthly.Residual flat dysplasia was treated with RFA until complete reversal dysplasia(CR-D)was achieved or progression to invasive Squamous cell cancer defined as infiltration into the submucosa layer or beyond.The main outcome measures were CR-D at 12 mo from start of treatment,long term durability,progression to cancer and adverse events.RESULTS:Twenty patients with squamous HGD/ESCC completed treatment protocol.Five patients(25%)had EMR before starting RFA treatment.CR-D was 50%at12 mo with a median of 1 RFA treatment,mean 1.5(range 1-3).Two further patients achieved CR-D with repeat RFA after this time.Eighty per cent with CR-D remain dysplasia free at latest biopsy,with median follow up 24 mo(IQR 17-54).Six of 20 patients(30%)progressed to invasive cancer at 1 year.Four patients(20%)required endoscopic dilatations for symptomatic structuring after treatment.Two of these patients have required serial dilatations thereafter for symptomatic dysphagia with a median of 4 dilatations per patient.The other 2 patients required only a single dilatation to achieve an adequate symptomatic response.One patient developed cancer during follow up after end of treatment protocol.CONCLUSION:The role of RFA in these patients re-mains unclear.In our series 50%patients responded at12 mo.These figures are lower than limited published data. | Rehan J Haidry Mohammed A Butt Jason Dunn Matthew Banks Abhinav Gupta Howard Smart Pradeep Bhandari Lesley Ann Smith Robert Willert Grant Fullarton Morris John Massimo Di Pietro Ian Penman Marco Novelli Laurence B Lovat | 2013 | World Journal of Gastroenterology2013，19，36： | 7 |
| 3 | 健康儿童接种流感疫苗效能与效果的系统评价摘要显示文摘 | Jefferson T Smith S Demicheli V Harnden A Rivetti A Di Pitetrantonj C 刘佑韧 | 2005 | 中国循证医学杂志2005，5，5： | 6 |
| 4 | Accuracy and Clinical Usefulness of Intracerebral Hemorrhage Grading Scores: A Direct Comparison in a UK Population显示文摘 | Adrian R. Parry-Jones Kamran A. Abid Mario Di Napoli Craig J. Smith Andy Vail Hiren C. Patel Andrew T. King Pippa J. Tyrrell | 2013 | Stroke2013，，7： | 2 |
| 5 | 遗传性肥胖与心房颤动的关系显示文摘观察性研究已经确定了体质量指数(body mass index,BMI)与心房颤动之间的关联。然而,从观察性研究中推断因果关系会受到混杂因素、逆因果关系和偏倚的影响。该研究的主要目的是应用BMI的遗传学预测因子评估BMI与心房颤动之间的因果关系。方法:纳入1987-2002年期间在美国、冰岛和荷兰实施的7个前瞻性人群队列研究中基线无心房颤动的欧洲血统个体51 646人, | 刘莉 叶鹏 Chatterjee NA Giulianini F Geelhoed B Lunetta KL Misialek JR Niemeijer MN Rienstra M Rose LM Smith AV Arking DE Ellinor PT Heeringa J Lin H Lubitz SA Soliman EZ Verweij N Alonso A Benjamin EJ Gudnason V Stricker BH van der Harst P Chasman DI Albert CM | 2017 | 中华高血压杂志2017，25，2： | 2 |
| 6 | Arbovirus infections in Sarawak:the role of the domestic pig显示文摘 | Simpson DI Smith CE Marshall TF | 1976 | Trans R Soc Trop Med Hyg1976，70，1： | 1 |
| 7 | Very large common fragile site genes and their potential role in cancer development 显示文摘 | Ge G Smith DI | 2014 | Cell Mol Life Sci2014，71，23： | 1 |
| 8 | Differential screening of a human chromosome-3 library identifies hepatocyte growth factor-like/macrophage stimulating protein and its receptor in injured lung possible implications for neuroendocrine cell survival 显示文摘 | Willett CG Smith DI Shridhar V | 1997 | JClin Invest1997，99，： | 1 |
| 9 | Impact of gastro- oesophageal reflux on microRNA expression, location and function显示文摘 | Smith CM Michael MZ Watson DI | 2013 | BMC Gastroenterol2013，13，： | 1 |
| 10 | Trails and tribu- lation of using bata - amyloid precursor protein immunocy- tochemistry to evaluate traumatic brain injury in adults显示文摘 | Graham DI Smith C Reichard R | 2004 | Forensic Sci intern2004，146，23： | 1 |
| 11 | Mir-148a improves response to chemotherapy in sensitive and resistant oesoph- ageal adenocarcinoma and squamous cell carcinoma cells 显示文摘 | Hummel R Watson DI Smith C | 2011 | J Gastrointest Surg2011，15，： | 1 |
| 12 | Association of APOE polymorphisms and pathological features in traumatic brain injury显示文摘 | Smith C Graham DI Murray LS | 2002 | Neuropathol Appl Neurobiol2002，28，： | 1 |
| 13 | Carboplatin in the treatment of meta- static carcinoid tumours and paraganglioma: a phase 显示文摘 | Jodrell DI Smith IE | 1990 | Cancer Chemother Pharmacol1990，26，1： | 1 |
| 14 | Prediction of movement during propofol/nitrous oxide anesthesia显示文摘 | Leslie K Seccler DI Smith WD | 1996 | Anesthesiology1996，84，： | 1 |
| 15 | Bevacizumab and osteonecrosis of the jaw: incidence and association with bisphosphonate therapy in three large prospective trials in advanced breast cancer显示文摘 | Valentina Guarneri David Miles Nicholas Robert Véronique Diéras John Glaspy Ian Smith Christoph Thomssen Laura Biganzoli Tanya Taran PierFranco Conte | 2010 | Breast Cancer Research and Treatment2010，，1： | 1 |
| 16 | Hypoglycaemia is a cause of axonal injury显示文摘 | Dolinak D Smith C Graham DI | 2000 | Neuropathol Appl Neurobiol2000，26，5： | 1 |
| 17 | Hypoglycaemia is a cause of axonal in- jury显示文摘 | Dolinak D Smith C Graham DI | 2000 | Neuropathol Appl Neurobiol2000，26，： | 1 |
| 18 | Surfactant effects on desorption of nonionic compounds显示文摘 | Di Cesare D Smith J A | 1994 | Reviews of Environmental Contamination & Toxicology1994，134，1： | 1 |
| 19 | C-reactive protein predicts hematoma growth in intracerebral hemorrhage 显示文摘 | Di Napoli M Parry-Jones AR Smith CJ | 2014 | Stroke2014，45，1： | 1 |
| 20 | SPLUNC1 promotes lung innate defense against Mycoplasma pneumoniae infection in mice 显示文摘 | Gally F Di Y P Smith S K | 2011 | Am J Pathol2011，178，5： | 1 |
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