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1Laparoscopic hepatectomy by curettage and aspiration:a new technique显示文摘背景 Laparoscopic 外科为最小的侵略和快速的手术后的恢复是有益的。自从在在 1990 年代的肝切除术的 laparoscopic hepatectomy 的使用,它在有效、安全的技术的一些机构 worldwide.Lack 被执行了因为肝办理是在 1998 由刮术和渴望为 laparoscopic hepatectomy 阻止一种新技术它开发的进一步的 development.We 的主要障碍。在这份报纸,我们总共在 7 年 practice.Methods 以后分析这种技术的临床的结果 59 个连续病人在我们的机构从 1998 年 8 月由刮术和渴望经历了 laparoscopic hepatectomy 到 2005 年 1 月。这些病人包括了 33 男性和 26 女性,与 47 年的吝啬的年龄。为肝 transecsion laparoscopic, Peng 的多功能的起作用的析象器(LPMOD ) 被使用。损害在 5 .Procedures 在 19 个病人,在 17 的良性的肝肿瘤,在 18 的 intrahepatic 演算,和另外的肝损害包括了恶意的肝肿瘤在 30 个病人,的包括的本地切除术离开了在 28 的侧面的 segmentectomy,和权利在 1 个 .Results Laparoscopic 手术的 hemihepatectomy 在 57 个病人被完成。二个病人(3.4%) 把操作变换成剖腹术。吝啬的操作时间是 143 分钟,吝啬的 intraoperative 血损失是 456 mi。手术后的医院停留的吝啬的长度是 7 天。复杂并发症在 2 个病人(3.4%) 发生了,并且由刮术没有 perioperative death.Conclusion Laparoscopic hepatectomy,渴望为肝切除术有效、安全。CAI Xiu-jun LIANG Xiao WANG Yi-fan YU Hong ZHENG Xue-yong HUANG Di-yu PENG Shu-you Department of General Surgery,Sir Run Run Shaw Hospital,College of Medicine Institute of Minimally Invasive Surgery of Zhejiang University,Hangzhou 310016,China (Cai XJ,Liang X,Wang YF,Yu H,Zheng XY,Huang DY and Peng SY) 2007Chinese Medical Journal2007,,20:11
2欧洲血管外科学会指南:第二部分——颈动脉狭窄患者的诊断和检查显示文摘在此,我们呈献颈动脉狭窄患者脑血管事件二级预防的欧洲血管外科学会指南,包括降脂治疗、抗血小板治疗以及其他危险因素控制。这些推荐均基于现有的临床试验证据。对颈动脉病患者需要采取积极的预防性治疗。我们还讨论了颈动脉狭窄的诊断和分级。Christos D. Liapis Sir Peter F. Bell Dimitri P. Mikhailidis Juharli Sivenius Andrew Nicolaides Jose Femandes e Fernandes Giorgio Biasi Ears Norgrer 赵颖(译) 谭泽锋(译) 徐安定(译) 2011国际脑血管病杂志2011,19,7:9
3Recent advances in heat shock protein-based cancer vaccines显示文摘BACKGROUND: Active immunotherapy has been successful in preventing many infectious diseases, and is being explored for its anti-tumor use. Purified antigens, peptides, gene-based systems and antigens contained in whole cells or cell lysates are used in specific active immunotherapy for cancer, known as cancer vaccines. Cancer vaccines do not directly kill tumor cells, but prime a specific humoral and/or cellular immune response against the tumor. Up to date, many kinds of cancer vaccines have been tested in the world and have shown their own advantages. Heat shock protein (HSP)-based cancer vaccine is one of the outstanding representatives. In this paper, we review recent advances in HSP-based cancer vaccines. DATA SOURCES: An English-language literature search was conducted using MEDLINE (1990-2005) on HSP, cancer vaccines and other related subjects. RESULTS: Several kinds of HSP-based cancer vaccines which have been explored worldwide, include tumor derived HSP-pepdde complex cancer vaccines, artificially reconstituted HSP-peptide complex cancer vaccines, HSPpeptide fusion protein cancer vaccines and HSP-based DNA cancer vaccines, etc. Many HSP-based cancer vaccines are being tested in clinical trials, and some are being tested in phase Ⅲ clinical trials at present. CONCLUSION: The available results in preclinical tests and clinical trials indicate that HSP-based cancer vaccines are promising in cancer therapy.Hao-Hao Wang, Chen-Yu Mao, Li-Song Teng and Jiang Cao Department of Oncology Surgery, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China Clinical Research Institute, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou 310016, China 2006Hepatobiliary & Pancreatic Diseases International2006,5,1:7
4欧洲血管外科学会指南:第1部分——颈动脉狭窄患者的预防显示文摘在此,我们呈献颈动脉狭窄患者脑血管事件二级预防的欧洲血管外科学会指南,包括降脂治疗、抗血小板治疗以及其他危险因素控制。这些推荐均基于现有的临床试验证据。对颈动脉疾病患者需要采取积极的预防性治疗。我们还讨论了颈动脉狭窄的诊断和分级。Christos D. Liapis Sir Peter F. Bell Dimitri P. Mikhailidis Juhani Sivenius Andrew Nicolaides Jose Femandes e Fernandes Giorgio Biasi Lars Norgren 董大伟(译) 刘小艳(译) 徐安定(译) 2011国际脑血管病杂志2011,19,6:7
5Prospective study of scoring system in selective intraoperative cholangiography during laparoscopic cholecystectomy显示文摘AIM: To evaluate of scoring system in predicting choledocholithiasis in selective intraoperative cholangiography (IOC) during laparoscopic cholecystectomy (LC).METHODS: The scoring system of predicting choledocholithiasis was developed during the retrospective study in 264 cases, and was tested in 184 to evaluate its predictive value in choledocholithiasis.RESULTS: The scoring system was developed in a retrospective study of 264 cases, the statistical analyses showed the predictive factors included sex, transaminase levels, alkaline phosphatase level, bilirubin level, and common bile duct diameter on ultrasonography. The scoring system was used in 184 cases prospectively, of which, 3 of 162 (1.9%) cases scoring <3 had choledocholithiasis, 17 of 22 (77.3 %) cases scores≥3 had choledocholithiasis. A case of scores≥3 or more prospectively should be considered highly intraoperative cholangiography during laparoscopic cholecystectomy.CONCLUSION: The scoring system can predict choledocholithiasis and is helpful in selection patietns for intraoperative cholangiography.Xiao-Dong Sun Xiao-Yan Cai Jun-Da Li Xiu-Jun Cai Yi-Ping Mu Jin-Min Wu Department of General Surgery,The Affiliated Sir Run Run Shaw Hospital,Zhejiang University Medical College,Hangzhou 310016,Zhejiang Province,China 2003World Journal of Gastroenterology2003,9,4:7
6比较法学的历史显示文摘波洛克(Sir Frederick Pollock,1845-1937)是19世纪著名的英国法学家。他曾就学于剑桥,亦曾在林肯律师会馆学习,获得律师资格。因之波洛克的学术视野,始终不曾局限于英国本土。他毕生的学术追求,亦体现出纵横两方面的贯通感。波洛克之学术贡献,首推其与梅特兰合著之《爱德华一世之前的英国法律史》(The History of English Law before the Time of Edward)。与一般的英国法制史多从1066年写起的谋篇方法不同,此书对罗马法有深入而广泛的论述。其内容还涉及蛮族与罗马法的关系、东罗马帝国时代的立法和教会法的产生,乃至中世纪罗马法的复兴。亦即对于英国法中的罗马法因素,二子皆高度重视之。此种体认,若无长时段大视野的贯通,颇难达致。波洛克的另外一篇论文《自然法史》,从亚里士多德和斯多亚学派写起,对自然法观念的发展及其对法律制度的影响作了系统的总结和阐述。对于研究自然法这一在西方法学史和法制史上影响深远的法学流派而言,是非常重要的参考资料。波洛克以史家之视野治法学,1883年入牛津接亨利·梅因的法理学教授席位。波洛克同时精通拉丁语、希腊语、法语和德语,他是对当时法学发展产生巨大影响的少数几位法学家之一。波洛克学术活动的黄金时期,正是比较法学在英国逐渐获得发展的时期。1895年,英国成立了比较立法学会。1900年,英国派遣波洛克参加了在巴黎召开的第一届世界比较法大会,他是这次会议上惟一的一名英美法系的代表。1903年,波洛克从牛津退职。这篇《比较法学的历史》是波洛克的退职演讲。但是我们不妨把它看做是波洛克治比较法学的心得所在。因此它既是一篇比较法学的简略总论,也是鼓励后来者在英国的比较法学界勇猛精进,大有所为的号令宣言。而不可避免地,它也是对英国法律史学家梅因的致敬之词。波洛克首先揭示了在法学研究中比较研究和历史研究之间的关系。在波洛克看来,这两者之间是相互为用、密切联系的。恰如德国著名比较法学家K.茨威格特和H.科茨所强调的那样:'一切法律史的研究都表明是运用比较法方法的一种作业,……我们记得,现代比较法的奠基者们主要是重要的法律史家。如果缺乏历史感,甚至现代比较法学者都不能够理解外国的解决办法。'〔1〕波洛克所以在此篇演讲中特重梅因,而对著名英国法学家布莱克斯通采取近乎严苛的'责备贤者'的态度,与波洛克对比较研究和历史研究之间关系的深刻体悟,有直接关系。隐然贯穿全篇的,是波洛克对比较法学发展的历史动力和理论基础的体察。波洛克意识到,法律的多样性是比较法存在的前提条件,并且无论怎样,为改进立法之故而研习国外之法律,始终是推动比较法发展的力量。但是,在波洛克看来,比较法学有其超乎功利主义目的之上的理论价值。比较法的思想基础,起初是自然法学,即探寻普世法的原则。波洛克以为,此种研究,意义不甚明显,乃至在其演讲中,一笔带过。波洛克真正命意所在,是他意识到实证主义和经验主义,才是比较法学最佳的培养基。而反观欧洲大陆流行的理性主义法哲学,由于其倚重先验方法,势不能对比较法学的发展起到促进作用。先验的理性主义不退潮,比较法学必不能大张其道。在这一点上,大木雅夫的观察不可谓不深刻:'相对于比较法发展的这种不利情况,人们自然而然地会把英国看做比较法思想的先驱之地。与欧洲大陆不同,英国既有着独立的法律传统,又是经验主义的故乡。'〔2〕由此我们不难解释为什么比较法于18世纪后方能兴起,为什么比较法在英国获得了相当的繁荣。从这个意义上讲,不是英国选择了比较法,而是比较法选择了英国。在这一主线指导之下,波洛克把历史上那些对比较法发展起到重要作用的思想巨擘的名字一一列出,略述其学术要旨。也把那些对比较法发展起到推动作用的历史事件,一并提及。此篇之所以名之曰《比较法学的历史》,概出于此。如果希望从中找到比较法发展的编年史,读者必将失望。但是如果注意到作者所察觉到的这一思想史的基本脉络,就不难理解,作者对历史资料,何以作如此大幅度的重新剪裁,甚至为突出主旨不惜令其支离破碎。尽管比较法学有所谓宏观比较和微观比较之说,但是毋庸置疑的是,若无一种整体的器识,治比较法学之境界,必非常有限。就比较法学而言,波洛克的可贵可重之处,即在于此。这篇演讲的风格,与其说是学术的,不如说是诗性的。波洛克运用了大量的典故和隐喻,高推比较法学在人类知识领域的位置,并号召后来者能由此出发,发扬光大之。学者与其从事的研究之间,必有一种近乎宗教使命似的感应交通,方可期其为大家。于此一广为流布之观点,余初持保留态度。译毕此文,于今信夫!波洛克(Sir Frederick Pollock) 2011比较法研究2011,25,5:7
7Pre-operative radiochemotherapy of locally advanced rectal cancer显示文摘AIM: To evaluate results of pre-operative radiochemotherapy followed by surgery for 15 patients with locally advanced un-resectable rectal cancer.METHODS: 15 patients with advanced non-resectable rectal cancer were treated with pre-operative irriadiation of 40-46 Gy plus concomitant chemotherapy (5-FU+LV and 5′-DFuR) (RCS group). For comparison, 27 similar patients,treated by preoperative radiotherapy (40-50 Gy) plus surgery were served as control (RS group).RESULTS: No radiochemotherapy or radiotherapy was interrupted and then was delayed because of toxicities in both groups. The radical resectability rate was 73.3% in the RCS group and 37.0% (P=0.024) in RS group. Sphincter preservation rates were 26.6% and 3.7% respectively (P=0.028). Sphincter preservation rates of lower rectal cancer were 27.3 % and 0.0 % respectively (P=0.014). Response rates of RCS and RS groups were 46.7 % and 18.5 %(P=0.053). The tumor downstage rates were 8 (53.3%)and 9 (33.3%) in these groups (P=0.206). The 3-year overall survival rates were 66.7 % and 55.6% (P=0.485), and the disease free survival rates were 40.1% and 33.2%(P=0.663). The 3-year local recurrent rates were 26.7%and 48.1% (P=0.174). No obvious late effects were found in either groups.CONCLUSION: High resectability is possible following preoperative radiochemotherapy and can have more sphincters preserved. It is important to improve the quality of the patients′ life even without increasing the survival or local control rates. Preoperative radiotherapy with concomitant full course chemotherapy (5-Fu+LV and 5′-DFuR) is effective and safe.Xiao-Nan Sun Qi-Chu Yang Jian-Bin Hu Department of Radiation Oncology,Sir Run Run Shaw Hospital,College of Medicine,Zhejiang University,Hangzhou 310016,Zhejiang Province,China 2003World Journal of Gastroenterology2003,9,4:6
8A history of high-power laser research and development in the United Kingdom显示文摘The first demonstration of laser action in ruby was made in 1960 by T.H.Maiman of Hughes Research Laboratories,USA.Many laboratories worldwide began the search for lasers using different materials,operating at different wavelengths.In the UK,academia,industry and the central laboratories took up the challenge from the earliest days to develop these systems for a broad range of applications.This historical review looks at the contribution the UK has made to the advancement of the technology,the development of systems and components and their exploitation over the last 60 years.Colin N.Danson Malcolm White John R.M.Barr Thomas Bett Peter Blyth David Bowley Ceri Brenner Robert J.Collins Neal Croxford A.E.Bucker Dangor Laurence Devereux Peter E.Dyer Anthony Dymoke-Bradshaw Christopher B.Edwards Paul Ewart Allister I.Ferguson John M.Girkin Denis R.Hall David C.Hanna Wayne Harris David I.Hillier Christopher J.Hooker Simon M.Hooker Nicholas Hopps Janet Hull David Hunt Dino A.Jaroszynski Mark Kempenaars Helmut Kessler Sir Peter L.Knight Steve Knight Adrian Knowles Ciaran L.S.Lewis Ken S.Lipton Abby Littlechild John Littlechild Peter Maggs Graeme P.A.Malcolm OBE Stuart P.D.Mangles William Martin Paul McKenna Richard O.Moore Clive Morrison Zulfikar Najmudin David Neely Geoff H.C.New Michael J.Norman Ted Paine Anthony W.Parker Rory R.Penman Geoff J.Pert Chris Pietraszewski Andrew Randewich Nadeem H.Rizvi Nigel Seddon MBE Zheng-Ming Sheng David Slater Roland A.Smith Christopher Spindloe Roy Taylor Gary Thomas John W.G.Tisch Justin S.Wark Colin Webb S.Mark Wiggins Dave Willford Trevor Winstone 2021High Power Laser Science and Engineering2021,9,2:5
9Factors influencing the results of treatment of bile duct injuries during laparoscopic cholecystectomy显示文摘BACKGROUND: The short-term results of repair of lapa- roscopic bile duct injuries have been well discussed, but the long-term results have been rarely reported. This study was undertaken to evaluate the factors influencing the outcome of repair of bile duct injuries caused by laparoscopic chole- cystectomy. METHODS: The outcomes of repair of bile duct injuries caused by laparoscopic cholecystectomy in 31 patients were reviewed retrospectively, and the effects of injury recogni- tion, cholangiography, repair modality and techniques on the long-term results were analyzed. RESULTS: Bile duct injuries were repaired successfully in 19 (95%) of 20 patients with injuries who had been recog- nized intraoperatively, and in 10 (90%) of 11 patients with injuries who had been recognized postoperatively. Repair was successful in 29 (93% ) of the 31 patients after complete cholangiography. Closure of partial division, laceration, or small perforation of the bile duct with or without T tube drainage was satisfactory in the 23 patients. End to end re- pair over T tube was successful in 2 transection patients, who were detected intraoperatively. Roux-en-Y hepatico- jejunostomy was used successfully to repair transection, ex- cision or stricture of the bile duct in 4 of 5 patients (80% ). CONCLUSION: Early detection of bile duct injuries caused by laparoscopy, complete evaluation of the biliary duct, and appropriate surgical modality and techniques are help- ful to improve the results of repair for laparoscopic bile duct injuries.Li-Bo Li, Xiu-Jun Cai, Yi-Ping Mou, Qi Wei and Xian-Fa Wang Hangzhou, China Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University Medical College, Hangzhou 310016, China 2005Hepatobiliary & Pancreatic Diseases International2005,4,1:2
10Emergence of novel strains of avian infectious bronchitis virus in Sweden显示文摘Shahid Hussain Abro Lena H.M. Renstr?m Karin Ullman Mats Isaksson Siamak Zohari Désirée S. Jansson Sándor Belák Claudia Baule 2011Veterinary Microbiology (-)2011,,2:2
11Sepsis, SIRS and CARS显示文摘Bone R C Sir Isaac Newton 1996Crit Care Med1996,24,7:2
12Mobility in different generations of older persons显示文摘Randi J. Hjorthol Lena Levin Anu Sirén 2010Journal of Transport Geography2010,,5:2
13Antidiabetic and antioxidant effects of Annona muricata (Annonaceae), aqueous extract on streptozotocin-induced diabetic rats显示文摘Ngueguim Tsofack Florence Massa Zibi Benoit Kouamouo Jonas Tchuidjang Alexandra Dzeufiet Djomeni Paul Désiré Kamtchouing Pierre Dimo Théophile 2014Journal of Ethnopharmacology2014,,2:2
14医学战线上的先驱者——伍连德博士(1876~1960)显示文摘1910年冬的满州(东北三省——译注),由于地面冻结而无法掩埋的尸体遍及街头。自中世纪以来还未被人们鲜知的一种凶恶的瘟疫自西西伯利亚向中国席卷而来。病人起初感到腋窝下胀痛、发高烧,而后咳稀薄泡沫血痰或纯血痰,并很快死去。 1911年春天,这种暴发性的流行性瘟疫被控制住之前。已有6万多人丧生。整个冬季,世界在观望、在等待。陈明生 Sir Philip manson Bahr 1994中国国境卫生检疫杂志1994,17,6:2
15Excluding infection through procalcitonin testing improves outcomes of congestive heart failure patients presenting with acute respiratory symptoms: Results from the randomized ProHOSP trial显示文摘Philipp Schuetz Alexander Kutz Eva Grolimund Sebastian Haubitz Désirée Demann Alaadin V?geli Fabienne Hitz Mirjam Christ-Crain Robert Thomann Claudine Falconnier Claus Hoess Christoph Henzen Robert J. Marlowe Werner Zimmerli Beat Mueller 2014International Journal of Cardiology2014,,3:2
16Solid-pseudopapillary tumor of the pancreas:CT and MRI features of 3 cases显示文摘BACKGROUND: Solid-pseudopapillary tumor of the pancreas is a rather rare but low-grade malignant tumor with good prognosis after surgical excision. METHODS: In 3 patients with solid-pseudopapillary tumor of the pancreas which were proved pathologically, the imaging features ( CT in all and MRI in one patient) of the tumor were analyzed. RESULTS: In the 3 female patients under 35-year-old who presented no jaundice, CT revealed that huge solid-cystic masses of the pancreatic head with calcification in one and slight dilation of the pancreatic duct in another, but without dilation of the bile duct system in all. MRI demonstrated mixed signal intensity on T1WI and T2WI of the mass in one patient. CT and MRI revealed obvious enhancement of the cystic wall and solid part of the masses. CONCLUSIONS: CT and MRI findings of solid-pseudopapillary tumor of the pancreas are characteristic, and the diagnosis can be made preoperatively with the combination of clinical features.Dan-Jun Dong and Shi-Zheng Zhang Department of Radiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China 2006Hepatobiliary & Pancreatic Diseases International2006,5,2:2
17Cerebral magnetic resonance imaging in quiescent Crohn's disease patients with fatigue显示文摘AIM To evaluate brain involvement in quiescent Crohn's disease (CD) patients with fatigue using quantitative magnetic resonance imaging(MRI).METHODS Multiple MRI techniques were used to assess cerebral changes in 20 quiescent CD patients with fatigue(defined with at least 6 points out of an 11-point numeric rating scale compared with 17 healthy age and gender matched controls without fatigue. Furthermore, mental status was assessed by cognitive functioning, based on the neuropsychological inventory including the different domains global cognitive functioning, memory and executive functioning and in addition mood and quality of life scores. Cognitive functioning and mood status were correlated with MRI findings in the both study groups.RESULTS Reduced glutamate + glutamine (Glx = Glu + Gln) concentrations (P = 0.02) and ratios to total creatine(P = 0.02) were found in CD patients compared with controls. Significant increased Cerebral Blood Flow(P = 0.05) was found in CD patients (53.08 ± 6.14 mL/100 g/min) compared with controls (47.60 ± 8.62 mL/100 g/min). CD patients encountered significantly more depressive symptoms (P < 0.001). Cognitive functioning scores related to memory (P = 0.007) and executive functioning (P = 0.02) were lower in CD patients and both scores showed correlation with depression and anxiety. No correlation was found subcortical volumes between CD patients and controls in the T1-weighted analysis. In addition, no correlation was found between mental status and MRI findings.CONCLUSION This work shows evidence for perfusion, neurochemical and mental differences in the brain of CD patients with fatigue compared with healthy controls.Sanne van Erp Ece Ercan Perla Breedveld Lianne Brakenhoff Eidrees Ghariq Sophie Schmid Matthias van Osch Mark van Buchem Bart Emmer Jeroen van der Grond Ron Wolterbeek Daniel Hommes Herma Fidder Nic van der Wee Tom Huizinga Désirée van der Heijde Huub Middelkoop Itamar Ronen Andrea van der Meulen-de Jong 2017World Journal of Gastroenterology2017,23,6:2
18Topotecan in the treatment of rcplased small cell lung cancer patients with poor pcrfommnce status 显示文摘Treat J Huang CH Lane SiR 2004Oncolgist2004,9,:1
19Production of recombinant HIV-1Nef(negativefactor)protein using Pichia pastoris and alow-temperature fed-batch strategy显示文摘Sirén N Weegar J Dahlbacka J 2006Biotechnol Appl Biochem2006,44,3:1
20Epidemic spreading on complex networks with community structure 显示文摘SIR Zhang J P Jin Z 2012Applied Mathematics and Computation2012,219,6:1
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