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| 1 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 2 | Histone H3 lysine 4 monomethylation modulates long- range chromatin interactions at enhancers显示文摘在 enhancers 和倡导者之间的远程的染色质相互作用为在哺乳动物和另外的 metazoans 的许多发展地控制的基因的抄写是必要的。当前,把远侧的 enhancers 连接到他们的特定的目标倡导者的准确机制尚待充分被阐明。这里,我们证明 4 monomethylation (H3K4me1 )(MLL3/4 ) 和 histone methyltransferases MLL3 和 MLL4 玩的提高特定的 histone H3 离氨酸在这个过程的一个活跃角色。我们在区分老鼠表明那胚胎的干细胞,在 enhancers 的 H3K4me1 的 MLL3/4-dependent 免职与染色质相互作用的增加的层次相关,而这 histone 修正的损失在区别期间在基因激活导致染色质相互作用和缺点的减少的层次。H3K4me1 便于 Cohesin 建筑群的招募,染色质组织的一个已知的管理者到在 vitro 并且在 vivo 的染色质,提供潜在的机制让 MLL3/4 支持在 enhancers 和倡导者之间的染色质相互作用。一起拿,我们的结果在在哺乳动物的房间在 enhancers 安排远程的染色质相互作用为 MLL3/4-dependent H3K4me1 支持一个角色。 | Jian Yan Shi-An A Chen Andrea Local Tristin Liu Yunjiang Qiu Kristel M Dorighi Sebastian Preissl Chloe M Rivera Chaochen Wang Zhen Ye Kai Ge Ming Hu Joanna Wysocka Bing Ren | 2018 | Cell Research2018，28，2： | 2 |
| 3 | Relationship between brain electrical activity and cortical perfusion in normal subjects显示文摘 | Andrew FL Sebastian HU Ian AC | 1999 | Psychiatry Research:Neuroimaging Section1999，90，： | 1 |
| 4 | The essence of bidirectional programming显示文摘Bidirectional transformations(BXs), programs with a forward transformation and a backward transformation that maintain consistency between input and output, are routinely written in ways that do not let programmers specify their behavior completely. Several bidirectional programming languages exist to aid programmers in writing BXs with increased maintainability but decreased expressiveness. Such languages allow programmers to write BXs as one program for both directions, which is easier to maintain than separate programs for each direction. However, the maintainability provided by existing bidirectional languages comes at the cost of expressiveness because the ambiguity of synchronization is solved by default strategies which are hidden from programmers. The programmers' inability to influence synchronization strategies has led to the proposal of a vast number of approaches that consider tailor-made synchronization strategies for particular applications.In this paper, we argue that such ambiguity is essential for BX and advocate that the synchronization strategy should not be hidden from programmers but considered from the start. We propose a novel approach to specifying so-called well-behaved bidirectional programs by their backward transformations, capable of expressing all aspects of a BX while retaining maintainability. Soundness of our approach results from a systematic analysis, based on existing mathematical concepts, of the instrumental laws of well-behaved BXs. We show that well-behaved BXs are uniquely determined by their backward transformations and corresponding forward transformations can be obtained for free. | FISCHER Sebastian HU ZhenJiang PACHECO Hugo | 2015 | Science China(Information Sciences)2015，58，5： | 1 |
| 5 | Association Between Variants of PRDM1 and NDP52 and Crohn’s Disease, Based on Exome Sequencing and Functional Studies显示文摘 | David Ellinghaus Hu Zhang Sebastian Zeissig Simone Lipinski Andreas Till Tao Jiang Bj?rn Stade Yana Bromberg Eva Ellinghaus Andreas Keller Manuel A. Rivas Jurgita Skieceviciene Nadezhda T. Doncheva Xiao Liu Qing Liu Fuman Jiang Michael Forster Gabriele Ma | 2013 | Gastroenterology2013，，2： | 1 |
| 6 | Transforming growth factor beta inhibition increases mortality and left ventricular dilatation after myocardial infarction显示文摘 | Stefan Frantz MD Kai Hu Anna Adamek Jürgen Wolf Abed Sallam Sebastian KG Maier Scott Lonning Hong Ling Georg Ertl Johann Bauersachs | 2008 | Basic Research in Cardiology2008，，5： | 1 |
| 7 | The debris disk candidates:eleven 24μm excess stars in the Spitzer SWIRE fields显示文摘We present the optical to mid-infrared SEDs of 11 debris disk candidates from Spitzer SWIRE fields.All the candidates are selected from SWIRE 24μm sources matched with both the SDSS star catalog and the 2MASS point source catalog. They show an excess in the mid-infrared at 24μm(KS-[24]Vega≥0.44),indicating the presence of a circumstellar dust disk.The observed optical spectra show that they are all late-type main-sequence stars covering the spectral types of FGKM.Their fractional luminosities are well above 5×10-5,even up to the high fractional luminosity of 1×10-3.The high galactic latitudes of SWIRE fields indicate that most of these candidates could belong to the oldest stars in the thick disk.Our results indicate that high fractional luminosity debris disks could exist in old solar-like star systems,though they are still quite rare.Their discovery at high galactic latitudes also provides an excellent opportunity for further study of the properties and evolution of debris disks in regions of the Galaxy with low densities of ISM,called ISM poor environments. | Hong Wu Chao-Jian Wu Chen Cao Sebastian Wolf Jing-Yao Hu | 2012 | Research in Astronomy and Astrophysics2012，12，5： | 0 |
| 8 | Laser-Induced Recoverable Fluorescence Quenching of Perovskite Films at a Microscopic Grain Scale显示文摘Understanding the fundamental properties of metal-halide perovskite materials is driving the development of novel optoelectronic applications.Here,we report the observation of a recoverable laser-induced fluorescence quenching phenomenon in perovskite films with a microscopic grain-scale restriction,accompanied by spectral variations.This fluorescence quenching depends on the laser intensity and the dwell time under Auger recombination dominated conditions.These features indicate that the perovskite lattice deformation may take the main responsibility for the transient and show a new aspect to understand halide perovskite photostability.We further modulate this phenomenon by adjusting the charge carrier recombination and extraction,revealing that efficient carrier transfer can improve the bleaching resistance of perovskite grains.Our results provide future opportunities to attain high-performance devices by tuning the perovskite lattice disorder and harvesting the energetic carriers. | Yuren Xiang Yameng Cao Wenqiang Yang Rui Hu Sebastian Wood Bowei Li Qin Hu Fan Zhang Jujie He Mozhgan Yavari Jinlai Zhao Yunlong Zhao Jun Song Junle Qu Rui Zhu Thomas P.Russell S.Ravi P.Silva Wei Zhang | 2022 | Energy & Environmental Materials2022，5，4： | 0 |
| 9 | 单细胞技术揭示肝癌免疫图谱与动态特征显示文摘文章简介肝细胞癌是世界范围内死亡率排名第三的癌症,其中中国的肝癌发病率居世界之先。肿瘤存在多种免疫逃逸机制,提出了研究肿瘤微环境中不同免疫细胞状态的重要性。而不同类型的单细胞测序技术则是研究不同类型免疫细胞的状态和动态的有力手段。本研究结合了两种单细胞测序技术,充分发挥不同数据类型的优势,获得高分辨率的肝癌免疫图谱。肿瘤中的树突状细胞是重要的抗原呈递细胞,除传统的树突状细胞外。 | Qiming Zhang Yao He Nan Luo Shashank J.Patel Yanjie Han Ranran Gao Madhura Modak Sebastian Carotta Christian Haslinger David Kind Gregory W.Peet Guojie Zhong Shuangjia Lu Weihua Zhu Yilei Mao Mengmeng Xiao Michael Bergmann Xueda Hu Sid P.Kerkar Anne B.Vogt Stefan Pflanz Kang Liu 彭吉润 任仙文 张泽民 | 2020 | 科学新闻2020，，2： | 0 |
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