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| 1 | The past, current and future trends in DNA vaccine immunisations显示文摘This review focuses on DNA vaccines, denoting the last two decades since the early substantiation of preclinical protection was published in Science in 1993 by Ulmer et al. In spite of being safely administered and easily engineered and manufactured DNA vaccine, it holds the future prospects of immunization by inducing potent cellular immune responses against infectious and non-infectious diseases. It is well documented that injection of DNA plasmid encoding a desired gene of interest can result in the subsequent expression of its products and lead to the induction of an immune response within a host. This is pertinent to prophylactic and therapeutic vaccination approach when the peculiar gene produces a protective epitope from a pathogen. The recent studies demonstrated by a number of research centers showed that these immune responses evoke protective immunity against several infectious diseases and cancers, which provides adequate support for the use of this approach. We attempt in this review to provide an informative and unbiased overview of the general principles and concept of DNA vaccines technology with a summary of a novel approach to the DNA vaccine, present investigations that describe the mechanism(s) of protective immunity provoked by DNA immunization and to highlight the advantages and disadvantages of DNA immunisation. | Sidgi Syed Anwer Abdo Hasson Juma Khalifa Zayid Al-Busaidi Talal Abdulmalek Sallam | 2015 | Asian Pacific Journal of Tropical Biomedicine2015，5，5： | 7 |
| 2 | Evaluation of anti-resistant activity of Auklandia(Saussurea lappa) root against some human pathogens显示文摘Objective:The antimicrobial activity of the ethanol extract of the Auklandia(Saussurea lappa)root plant was investigated to verify its medicinal use in the treatment of microbial infections.Methods:The antimicrobial activity of the ethanol extract was tested against clinical isolates ofsome multidrug-resistant bacteria using the agar well diffusion method.Commercial antibioticswere used as positive reference standards to determine the sensitivity of the clinical isolates.Results:The extracts showed significant inhibitory activity against clinical isolates of methicillinresistantStaphylococcus aureus,Pseudomonas aeruginosa,Escherichia coli,Klebsiella pneumonia,Extended Spectrum Beta-Lactemase,Acinetobacter baumannii.The minimum inhibitory concentration values obtained using the agar dilution test ranged from 2.0μg/μL-12.0μg/μL.In the contrary the water extract showed no activity at all against the tested isolates.Furthermore,theresults obtained by examining anti-resistant activity of the plant ethanolic extract showed thatat higher concentration of the plant extract(12μg)all tested bacteria isolates were inhibited with variable inhibition zones similar to those obtained when we applied lower extract concentrationusing the well diffusion assay.Conclusion:The results demonstrated that the crude ethanolicextract of the Auklandia(Saussurea lappa)root plant has a wide spectrum of activity suggestingthat it may be useful in the treatment of infections caused by the above clinical isolates(humanpathogens). | Sidgi Syed Anwer Hasson Mohammed Saeed Al-Balushi KhazinaAlharthy JumaZaidAl-Busaidi MunaSulimanAldaihani Mohammed Shafeeq Othman Elias Antony Said Omar Habal Talal Abdullah Sallam Ali Abdullah Aljabri Mohamed AhmedIdris | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，7： | 2 |
| 3 | Long-term pituitary down-regulation before invitro fertilization (IVF) for women with endometriosis显示文摘 | Sallam H Garcia-Velasco J Dias S | 2006 | Cochrane Database Syst Rev2006，25，00： | 1 |
| 4 | Thin-layer chromatography of some ergot alkaloids显示文摘 | SALLAM L A R NAIM N EI-REFAI A H | 1977 | Fresenius J Anal Chem1977，284，： | 1 |
| 5 | Sperm velocity and morphology, female characteristics, and the hypo-Osmotic swelling test as predictors of fertilization potential: experience from the IVF model 显示文摘 | Sallam HN Ezzeldin F Sallam A | 2003 | Int J Fertil Womens Med2003，48，2： | 1 |
| 6 | Sperm velocity and morphology,female characteristics,and the hypo-osmotic swelling test as predictors of fertilization potential:experience from the IVF model显示文摘 | Sallam HN Ezzeldin F Sallam A | 2003 | Int J Fertil Womens Med2003，48，2： | 1 |
| 7 | Sperm velocityandmorphology,femalecharacteristics,andthehypo-os-moticswellingtestaspredictorsoffertilizationpotential:experiencefromtheIVF model显示文摘 | Sallam HN EzzeldinF Sallam A etal | 2003 | IntJFertilWomensMed2003，48，2： | 1 |
| 8 | Gastic slow waves,gastrointestinal symptoms and peptides in systemic sclerosis patients显示文摘 | MeNearney TA Sallam HS Hunnicutt SE | 2009 | Neurogastroentero Moti12009，21，12： | 1 |
| 9 | Liquid Breakup at the Surface of Turbulent Round Liquid Jets in Still Gases 显示文摘 | Sallam K A Dai Z Faeth M | 2002 | International Journal of Multiphase Flow2002，28，： | 1 |
| 10 | The prokinetic face of ghrelin显示文摘 | Sallam HS Chen JD | 2010 | International Journal of Peptides Volume2010，49，3： | 1 |
| 11 | Antioxidant and antimicrobial effects of garlic in chicken sausage 显示文摘 | SALLAM K I ISHIOROSHI M SAMEJIMA K | 2004 | LWT- Food Science and Technology2004，37，8： | 1 |
| 12 | Breakup of aeratedliquid jets in subsonic crossflow显示文摘 | Miller B Sallam K A Bingabr M | 2008 | Journal of Propulsionand Power2008，24，2： | 1 |
| 13 | Occurrence and molecular identification of Vibrio parahoemolyticus in retail shellfish in Mansoura, Egypt显示文摘 | Abd-Elghany S M Sallam K I | 2013 | Food Control2013，33，2： | 1 |
| 14 | Diagnostic value of serum kallikrein-related peptidases 6 and 10 versus CA125 in ovarian cancer显示文摘 | E1 Sherbini MA Sallam MM Shaban EA | | 0，，04： | 1 |
| 15 | Antimicrobial and antioxidant effects of sodium acetate,sodium lactate,and sodium citrate in refrigerated sliced salmon显示文摘 | Sallam K I | | 0，，： | 1 |
| 16 | An Adaptive Protection Scheme for Advanced Series Compensated (ASC) Transmission Lines显示文摘 | GIRGIS A A SALLAM A A EL-DIN A K | 1998 | IEEE Trans on Power Delivery1998，13，2： | 1 |
| 17 | Joint low-complexity equalization and cartier frequency offsets compensa- tion scheme for MIMO SC-FDMA systems显示文摘 | AL-KAMALI F S DESSOUKY M I SALLAM B M | 2012 | IEEE Transactions on Wireless Communications2012，11，3： | 1 |
| 18 | Unconditionally stable Cl- cubic spline collocation method for solving parabolic equations 显示文摘 | Sallam S Naim Anwar M Abdel-Aziz M R | 2004 | Intern J Computer Math2004，81，7： | 1 |
| 19 | Antioxidant and antimicrobial effects of garlic in chicken sausage显示文摘 | Sallam K I Ishioroshi M Samejima K | 2004 | Lebensmittel-Wissenschaftund-Technologie2004，37，： | 1 |
| 20 | Effect of sodium dodecyl sulphate (SDS) on the viability and fertility of damascous goat spermatozoa 显示文摘 | EL-KON II SALLAM AA ASHMAWY TM | 2010 | Global Veterinaria2010，4，6： | 1 |
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