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| 1 | 环境因子对木棉种子萌发的影响显示文摘木棉(Bombax malabaricum DC.)是一种可以生长在干热河谷的落叶大乔木。河谷内,木棉成年树木生长良好,有大量结实,而其周围却很少有种苗出现。通过室内条件研究木棉种子的物理特性和萌发的生物学特性,可以了解该物种种子萌发对环境因子的需求,为探讨木棉在干热河谷内自然种群更新难和萌发阶段对这一特殊生境的适应性提供理论依据。经测定,木棉种子千粒重为39.08 g,比同科的其它物种要轻。四唑(TTC,1.0%)染色测定种子生活力的结果表明有生活力种子占64.0%。种皮对吸胀无障碍,种子在25℃吸胀2 d时就开始萌发。检测了环境因子对种子萌发和幼苗生长的影响,结果表明,种子萌发对光照不敏感而且对温度有较广的适应性,15—35℃都可以萌发,25—35℃萌发率无显著差异,但随温度升高,萌发速率加快,幼苗长势增加;萌发过程对渗透胁迫敏感,聚乙二醇(PEG)浓度为0.10 g/mL时萌发率较对照显著下降,0.15 g/mL时种子就不能萌发;室温吸胀24 h的种子对热激敏感,42℃热激2 h后萌发率就已经显著下降;室温下水杨酸(SA,1,10,100 mg/L)浸种24 h,没有提高种子在萌发期间对干旱和热激的抗性。可见,高温和干旱是限制木棉种子成功萌发的关键因子,然而发现,温度较高时水分过大也会造成萌发后幼苗的死亡。 | 郑艳玲 马焕成 Scheller Robert 高柱 郑元 | 2013 | 生态学报2013，33，2： | 43 |
| 2 | Oligodendroglial GABAergic Signaling:More Than Inhibition!显示文摘GABA is the main inhibitory neurotransmitter in the CNS acting at two distinct types of receptor:ligand-gated ionotropic GABAA receptors and G protein-coupled metabotropic GABAB receptors,thus mediating fast and slow inhibition of excitability at central synapses.GABAergic signal transmission has been intensively studied in neurons in contrast to oligodendrocytes and their precursors(OPCs),although the latter express both types of GABA receptor.Recent studies focusing on interneuron myelination and interneuron-OPC synapses have shed light on the importance of GABA signaling in the oligodendrocyte lineage.In this review,we start with a short summary on GABA itself and neuronal GABAergic signaling.Then,we elaborate on the physiological role of GABA receptors within the oligodendrocyte lineage and conclude with a description of these receptors as putative targets in treatments of CNS diseases. | Xianshu Bai Frank Kirchhoff Anja Scheller | 2021 | Neuroscience Bulletin2021，37，7： | 4 |
| 3 | IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer显示文摘 | Sergei Grivennikov Eliad Karin Janos Terzic Daniel Mucida Guann-Yi Yu Sivakumar Vallabhapurapu Jürgen Scheller Stefan Rose-John Hilde Cheroutre Lars Eckmann Michael Karin | 2009 | Cancer Cell2009，，2： | 3 |
| 4 | Cell wallβ-1,4-galactan regulated by the BPC1/BPC2-GALS1 module aggravates salt sensitivity in Arabidopsis thaliana显示文摘Salinity severely reduces plant growth and limits agricultural productivity.Dynamic changes and rearrangement of the plant cell wall is an important response to salt stress,but relatively little is known about the biological importance of specific cell wall components in the response.Here,we demonstrate a specific function ofβ-1,4-galactan in salt hypersensitivity.We found that salt stress induces the accumulation ofβ-1,4-galactan in root cell walls by up regulating the expression of GALACTAN SYNTHASE 1(GALS1),which encodes aβ-1,4-galactan synthase.The accumulation ofβ-1,4-galactan negatively affects salt tolerance.Exogenous application of D-galactose(D-Gal)causes an increase inβ-1,4-galactan levels in the wild type and GALS1 mutants,especially in GALS1 overexpressors,which correlated with the aggravated salt hypersensitivity.Furthermore,we discovered that the BARLEY B RECOMBINANT/BASIC PENTACYSTEINE transcription factors BPC1/BPC2 positively regulate plant salt tolerance by repressing GALS1 expression andβ-1,4-galactan accumulation.Genetic analysis suggested that GALS1 is genetically epistatic to BPC1/BPC2 with respect to the control of salt sensitivity as well as accumulation ofβ-1,4-galactan.Taken together,our results reveal a new regulatory mechanism by whichβ-1,4-galactan regulated by the BPC1/BPC2-GALS1 module aggravates salt sensitivity in Arabidopsis thaliana. | Jingwei Yan Ya Liu Lan Yang Huan He Yun Huang Lin Fang Henrik Vibe Scheller Mingyi Jiang Aying Zhang | 2021 | Molecular Plant2021，14，3： | 3 |
| 5 | 双酶电极法测定L-苯丙氨酸的研究显示文摘本文以Clark氧电极为基础 ,把水杨酸羟化酶和苯丙氨酸脱氢酶同时固定在氧电极的表面 ,制成了双酶生物传感器。在磷酸缓冲液中 ,水杨酸浓度为 0 .5mmol/L ,烟酰胺腺嘌呤二核甘酸 (NAD+)的浓度为 1 .0mmol/L ,其响应电流的变化对应反池中L 苯丙氨酸的浓度在 0~ 0 .1 5mmol/L之内有良好的线性范围。 | 陈滋青 胡军 Axel Warsinke Frieder Scheller | 2000 | 工业微生物2000，30，1： | 2 |
| 6 | Treatment of small coronary arteries with a paclitaxel-coated balloon catheter显示文摘 | Martin Unverdorben Franz X. Kleber Hubertus Heuer Hans-Reiner Figulla Christian Vallbracht Matthias Leschke Bodo Cremers Stefan Hardt Michael Buerke Hanns Ackermann Michael Boxberger Ralf Degenhardt Bruno Scheller | 2010 | Clinical Research in Cardiology2010，，3： | 2 |
| 7 | 星形胶质细胞和嗅鞘细胞之间的Panglial缝隙连接介导Ca^(2+)瞬变的传递和神经血管耦合显示文摘星形胶质细胞排列在有高度组织性的缝隙连接耦合网络中,通过Ca^(2+)波的传播进行通信。星形胶质细胞不仅与邻近的星形胶质细胞结合,而且还与少突胶质细胞偶联,形成panglial合胞体。但panglial合胞体中的神经胶质细胞是否通过Ca^(2+)信号传递信息尚不清楚。我们使用共聚焦Ca^(2+)成像来研究小鼠嗅球中星形胶质细胞和嗅鞘神经胶质细胞(OECs)之间的细胞间通讯。研究结果表明,通过'笼状' ATP和'笼状' tACPD的局部光解可引起的肾小球旁星形胶质细胞中的Ca^(2+)瞬变,导致OEC中随之而来的Ca^(2+)反应。这种从星形胶质细胞到OEC的Ca^(2+)反应的传递在神经元抑制的情况下持续存在,但是当用甘珀酸抑制缝隙连接偶联时消失。当通过DHPG的抽吸在OEC中直接诱发Ca^(2+)瞬变时,它们导致肾小球星形胶质细胞中的Ca^(2+)反应延迟,表明Ca^(2+)信号的panglial传递以双向方式发生。此外,从星形胶质细胞到OEC的Ca^(2+)信号的panglial传递导致嗅觉神经层中OEC相关血管的收缩。本研究结果证明了在缝隙连接耦合的panglial网络中,不同类别的神经胶质细胞之间通过Ca^(2+)进行信号传递,并借此调节嗅球中血管的直径。 | Beiersdorfer A Scheller A Kirchhoff F Lohr C 聂昊 | 2019 | 神经损伤与功能重建2019，14，3： | 2 |
| 8 | Two year follow-up after treatment of coronary in-stent restenosis with a paclitaxel-coated balloon catheter显示文摘 | Bruno Scheller Christoph Hehrlein Wolfgang Bocksch Wolfgang Rutsch Dariush Haghi Ulrich Dietz Michael B?hm Ulrich Speck | 2008 | Clinical Research in Cardiology2008，，10： | 2 |
| 9 | Inhibition of neutrophils’ chemiluminescence by ethanol extract of propolis (EEP) and its phenolic components显示文摘 | W. Krol S. Scheller Z. Czuba T. Matsuno G. Zydowicz J. Shani M. Mos | 1996 | Journal of Ethnopharmacology1996，，1： | 2 |
| 10 | Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling显示文摘 | Jones Simon A Scheller Jürgen Rose-John Stefan | 2011 | Journal of Clinical Investigation2011，，9： | 2 |
| 11 | Outcome of Operative Therapy of Hepatic Metastatic Stomach Carcinoma: A Retrospective Analysis显示文摘 | Claus Schildberg R. Croner S. Merkel V. Schellerer V. Müller S. Yedibela W. Hohenberger G. Peros A. Perrakis | 2012 | World Journal of Surgery2012，，4： | 2 |
| 12 | Vadim Fridman Bioelectrocatalysis by redox enzymes at modified electrodes显示文摘 | Frieder W Scheller Ulla Wollenberger | 2002 | Reviews in Molecular Biotechnology2002，，82： | 2 |
| 13 | The pro- and anti-inflammatory properties of the cytokine interleukin-6显示文摘 | Jürgen Scheller Athena Chalaris Dirk Schmidt-Arras Stefan Rose-John | 2011 | BBA - Molecular Cell Research2011，，5： | 2 |
| 14 | The Cooperative Activities of CSLD2, CSLD3, and CSLD5 Are Required for Normal Arabidopsis Development显示文摘Glycosyltransferases of the Cellulose Synthase Like D (CSLD) subfamily have been reported to be involved in tip growth and stem development in Arabidopsis. The csld2 and csld3 mutants are root hair defective and the csld5 mutant has reduced stem growth. In this study, we produced double and triple knockout mutants of CSLD2, CSLD3, and CSLD5. Unlike the single mutants and the csld2/csld3 double mutant, the csld2/csld5, csld3/csld5, and csld2/ csld3/csld5 mutants were dwarfed and showed severely reduced viability. This demonstrates that the cooperative activities of CSLD2, CSLD3, and CSLD5 are required for normal Arabidopsis development, and that they are involved in important processes besides the specialized role in tip growth. The mutant phenotypes indicate that CSLD2 and CSLD3 have overlapping functions with CSLD5 in early plant development, whereas the CSLD2 and CSLD3 proteins are non-redundant. To determine the biochemical function of CSLD proteins, we used transient expression in tobacco leaves. Microsomes containing heterologously expressed CSLD5 transferred mannose from GDP–mannose onto endogenous acceptors. The same activity was detected when CSLD2 and CSLD3 were co-expressed but not when they were expressed separately. With monosaccharides as exogenous acceptors, microsomal preparations from CSLD5-expressing plants mediated the transfer of mannose from GDP–mannose onto mannose. These results were supported by immunodetection studies that showed reduced levels of a mannan epitope in the cell walls of stem interfascicular fibers and xylem vessels of the csld2/csld3/csld5 mutant. | Lan Yin Yves Verhertbruggen Ai Oikawa Chithra Manisseri Bernhard Knierim Lina Prak Jacob Kriiger Jensen Paul Knox Manfred Auer William G.T. Willatsa and Henrik Vibe Scheller | 2011 | Molecular Plant2011，4，6： | 2 |
| 15 | Production of spider silk proteins in tobacco and potato显示文摘 | SCHELLER J GUHRS K H GROSSE F | 2001 | Nat Biotechnol2001，19，： | 1 |
| 16 | 显示文摘 | STOCKLEIN W SCHELLER F W | 2002 | Anal Chim Acta2002，470，： | 1 |
| 17 | Purification of Spider Silk-elastin from Transgenic Plants and Application for Human Chondrocyte Proliferation显示文摘 | Jürgen Scheller Daniele Henggeler Angelika Viviani Udo Conrad | 2004 | Transgenic Research2004，，1： | 1 |
| 18 | Interleukin-6 and its receptor from bench to bedside显示文摘 | Scheller J Rose-John S | 2006 | Med Microbiol Immunol2006，195，2： | 1 |
| 19 | Long-term, multilineage hematopoiesis occurs in the combined absence of 13-catenin and ',/-catenin 显示文摘 | Jeannet G Scheller M Scarpellino L | 2008 | Blood2008，111，1： | 1 |
| 20 | Purification of spider silk elastin from transgenic plants and application for human ehondrocyte proliferation 显示文摘 | SCHELLER J HENGGELER D VIVIANI A | 2004 | Transgenic Res2004，13，1： | 1 |
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