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| 1 | One hundred and seventy-eight consecutive pancreatoduodenectomies without mortality:role of the multidisciplinary approach显示文摘BACKGROUND:Pancreatoduodenectomy offers the only chance of cure for patients with periampullary cancers.This,however,is a major undertaking in most patients and is associated with a significant morbidity and mortality.A multidisciplinary approach to the workup and follow-up of patients undergoing pancreatoduodenectomy was initiated at our institution to improve the diagnosis,resection rate,mortality and morbidity.We undertook the study to assess the effect of this approach on diagnosis,resection rates and short-term outcomes such as morbidity and mortality.METHODS:A prospective database of patients presenting with periampullary cancers to a single surgeon between April 2004 and April 2010 was reviewed.All cases were discussed at a multidisciplinary meeting comprising surgeons,gastroenterologists,radiologists,oncologists,radiation oncologists,pathologists and nursing staff.A standardized investigation and management algorithm was followed.Complications were graded according to the Clavien-Dindo classification.RESULTS:A total of 295 patients with a periampullary lesion were discussed and 178 underwent pancreatoduodenectomy (resection rate 60%).Sixty-one patients (34%) required either a vascular or an additional organ resection.Eighty-nine patients experienced complications,of which the commonest was blood transfusion (12%).Thirty-four patients (19%) had major complications,i.e.grade 3 or above.There was no in-hospital,30-day or 60-day mortality.CONCLUSIONS:Pancreatoduodenectomy can safely be performed in high-volume centers with very low mortality.The surgeon's role should be careful patient selection,intensive preoperative investigations,use of a team approach,and an unbiased discussion at a multidisciplinary meeting to optimize the outcome in these patients. | Jaswinder S Samra Raul Alvarado Bachmann Julian Choi Anthony Gill Michael Neale Vikram Puttaswamy Cameron Bell Ian Norton Sarah Cho Steven Blome Ritchie Maher Sivakumar Gananadha Thomas J Hugh | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，4： | 8 |
| 2 | Minimizing transmission loss using inspired ant colony optimization and Markov Chain Monte Carlo in underwater WSN environment显示文摘In Underwater Wireless Sensor Networks(UWSNs),the most important challenging issues are propagation delay,high error probability,high latency,high communication cost,limited bandwidth,limited memory,low packet delivery ratio,and transmission loss.In our proposed work,the various efforts are taken to minimize the propagation delay and transmission loss during data transmission in an underwater environment.A hybrid mechanism is implemented to improve energy efficiency for faster data transmission in underwater WSN.In the underwater environment of acoustic channel condition,propagation delay and transmission loss lead to high complexity in accessing the information and also it is difficult to obtain the Channel Status Information(CSI).To address this problem,Ant Colony Optimization(ACO)routing with Markov Chain Monte Carlo(MCMC)algorithm is used and to capture the transmission loss in the MCMC approach,CSI Forecast Prediction(FP)algorithm is used.The experimental simulations are evaluated by utilizing the performance evaluation metrics such as Transmission Loss,Probability Density Function,Average Delay and Throughput.From the simulation results it is evident that the proposed algorithm,ACO-MCMC has recorded the minimum transmission loss,increase in probability density function,minimum average delay and maximum throughput of the network when compared to the existing algorithms. | Raj Priyadarshini R Sivakumar N | 2019 | Journal of Ocean Engineering and Science2019，4，4： | 7 |
| 3 | Virus-Induced Gene Silencing Offers a Functional Genomics Platform for Studying Plant Cell Wall Formation显示文摘导致病毒的基因 silencing (VIGS ) 是为对在 post-genomic 时代的植物基因功能的快速的评价的一个强大的基因工具。这里,我们成功地实现了基于的一个烟草格格声病毒(TRV ) 学习在 Nicotiana benthamiana 涉及主要或第二等的房间墙形成的基因的函数的 VIGS 系统种。一个 3 星期的 post-VIGS 时间框架是足够的在茎的解剖结构和主要、第二等的房间墙的化学作文观察 phenotypic 改变。我们使用了在第二等的生长期间表明细胞墙聚合物合成的那改变的指导 glycan 的 monoclonal 抗体 VIGS 植物分阶段执行的细胞墙从木质的干细胞墙在部件的 extractability 上有深刻效果。因此,和房间墙部件介绍的基于 TRV 的 VIGS 方法为从一个 bioenergy 观点学习植物房间墙形成提供一个高产量的基因发现平台。 | Xiaohong Zhu Sivakumar Pattathil Koushik Mazumder Amanda Brehm Michael G. Hahn S.P. Dinesh-Kumar Chandrashekhar P. Joshi | 2010 | Molecular Plant2010，3，5： | 6 |
| 4 | Regulation and Function of NF-κB Transcription Factors in the Immune System显示文摘 | Sivakumar Vallabhapurapu Michael Karin | 2009 | Annual Review of Immunology2009，，： | 5 |
| 5 | Arabidopsis thaliana T-DNA Mutants Implicate GAUT Genes in the Biosynthesis of Pectin and Xylan in Cell Walls and Seed Testa显示文摘Galacturonosyltransferase 1 (GAUT1 ) 是从 uridine 5-diphosphogalacturonic 酸转移 galacturonic 酸到果胶的多糖 homogalacturonan 上的 1,4-D-galacturonosyltransferase (斯特林等, 2006 ) 。25 成员 Arabidopsis thaliana GAUT1 相关的基因家庭编码 15 GAUT 和 10 象 GAUT 一样(GATL ) 蛋白质与,分别地 5684 和 4253% 氨基酸顺序类似到 GAUT1。AtGAUTs 的以前的种系发生的分析显示了三 clades:通过 C 的 A。Arabidopsis,白杨和米饭 GAUT 家庭的比较种系发生的分析有亚 classified GAUT 进七 clades:clade A-1 (GAUT 1 ~ 3 ) ;A-2 (GAUT4 ) ;A-3 (GAUT 5 和 6 ) ;A-4 (GAUT7 ) ;B-1 (GAUT 8 和 9 ) ;B-2 (GAUT 10 和 11 ) ;并且 clade C (GAUT 12 ~ 15 ) 。Arabidopsis GAUT 有比得上白杨 orthologs 的分布,与 GAUT2 的例外,它在白杨是不在的。然而,瑞斯没有 GAUT 的 orthologs 2 和 12 并且有 GAUT 的多重明显的 orthologs 1, 4,和 7 与 Arabidopsis 或白杨相比。为 15 Arabidopsis GAUT 基因中的 13 个的 26 同型结合的 T-DNA 插入异种的房间墙 glycosyl 残余作文显著地并且 reproducibly 在 6, 8, 9, 10, 11, 12, 13,和 14 从野类型的 Arabidopsis 的围的 gaut 异种的特定的纸巾揭示不同房间墙。果胶和木聚糖多糖被 GAUT 功能的损失影响,由改变的 galacturonic 酸示威了不同 gaut 异种的木糖, rhamnose,半乳糖,和 arabinose 作文围。墙 glycosyl 残余在 gaut 异种之中观察的组合显型建议在果胶或木聚糖的至少六个不同 biosynthetic 连接被损害在这些 GAUT 基因影响。证据也被介绍在种子粘液扩大并且在种子墙和粘液作文中为 GAUT11 支持一个角色。 | Kerry H. Caffall Sivakumar Pattathil Sarah E. Phillips Michael G. Hahn Debra Mohnen | 2009 | Molecular Plant2009，2，5： | 5 |
| 6 | Mosquito adulticidal and repellent activities of botanical extracts against malarial vector,Anopheles stephensi Liston(Diptera:Culicidae)显示文摘To determine the adulticidal and repellent activities of different solvent leaf extracts of Eclipta alba(E.alba) and Andrographis paniculata(A.paniculata) against malarial vector, Anopheles stephensi(An.stephensi)Mathods:Adultieidal efficacy of the crude leaf extracts of E.alba and.1.paniculata with five different solvents like benzene,hexane.ethyl acetate. methanol and chloroform was tested against the five to six dav old adult female mosquitoes of An.stephensi.The adult mortality was observed after 24 h under the laboratory conditions.The repellent efficacy was determined against An,stephensi mosquito species at three concentrations viz.,1.0,2.5 and 5.0 mg/cm2 under laboratory conditions.Results:Among the tested solvents the maximum efficacy was observed in the methanol extract.The LC50 and LC90 values of E.alba and A.paniculata against adults of An.stephensi were 150.36.130.19 ppm and 285.22.244.16 ppm. respectively.No mortality was obsened in controls.The chi-square values were significant at P<0.05 lev el.Methanol extract of E.alba and A.paniculata was produce maximum repellency against An.stephensi.Conclusions:From the results it can be concluded the crude extract of E. nihil and A.paniculata was an excellent potential for controlling An.stephensi mosquitoes. | Marimuthu Govindarajan Rajamohan Sivakumar | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，12： | 4 |
| 7 | Estimation of total phenolic content, cytotoxicity and in–vitro antioxidant activity of stem bark of Moringa oleifera显示文摘 | MR Kumbhare V Guleha T Sivakumar | 2012 | Asian Pacific Journal of Tropical Disease2012，，2： | 4 |
| 8 | 催化层掺杂共价有机框架材料提升高温聚电解质膜燃料电池性能显示文摘基于磷酸掺杂聚苯并咪唑(PBI)高温聚电解质膜燃料电池(HT-PEMFC)具有环境耐受性好、水热管理简单等优点,被认为是未来PEMFC的发展方向。而减少其运行过程中磷酸电解质的流失是维持HT-PEMFC性能稳定性的关键因素。在本工作中,我们提出在电极催化层中引入一种席夫碱型(SNW-1)共价有机框架(COF)材料的策略来减少膜电极(MEA)中的磷酸流失,从而增强HT-PEMFC的耐久性。由于该COF材料中大量与磷酸分子匹配的微孔和特定的官能团结构,使其不仅拥有优越的磷酸保留能力,而且具有良好的质子传导能力,因此该HT-PEMFC在电池加速老化测试中展现出很好的稳定性。此外,发现在催化层中引入5%–10%的COF材料,可有效提高电极电化学活性面积并降低电池的欧姆内阻和电荷转移电阻,从而可进一步提高HT-PEMFC放电性能。在150℃、氢/空和常压操作条件下,工作电压0.6 V时催化层中添加10%COF材料的电池电流密度达到0.361 A·cm^(−2),较常规电池性能提升30%左右。该工作说明在催化层中掺杂适量COF材料有希望成为提升HT-PEMFC性能和耐久性的一种有效策略。 | 田立亮 张玮琦 解政 彭凯 马强 徐谦 Sivakumar Pasupathi 苏华能 | 2021 | 物理化学学报2021，37，9： | 3 |
| 9 | Alkali and Silane Treatments towards Exemplary Mechanical Properties of Kenaf and Pineapple Leaf Fibre-reinforced Composites显示文摘Following the contemporary research trend of exploring the potential of eco-friendly natural fibres,this work studies the effects of alkali and silane treatments,with varying concentrations,on the mechanical characterization of composites reinforced with kenaf and pineapple leaf fibre(PALF).Kenaf-and PALF-based composites were fabricated through the heat compression method.Their mechanical characterization was then performed to evaluate the tensile,flexural and impact properties.The findings concluded that chemical treatments indeed enhanced the mechanical properties of composite materials.5%NaOH and 3%silane treatments can respectively provide the optimum mechanical properties to the kenaf fibre and PALF reinforced composites.Chemical treatment results evidenced that silane-treated composites exhibit higher mechanical properties compared to the NaOH-treated composites.When comparing the mechanical properties of kenaf-and PALF-reinforced polypropylene composites,the overall results show that composites based on PALF have superior mechanical properties. | Ng Lin Feng Sivakumar Dhar Malingam Nadlene Razali Sivarao Subramonian | 2020 | Journal of Bionic Engineering2020，17，2： | 3 |
| 10 | Larvicidal efficacy of Cassia fistula Linn. leaf extract against Culex tritaeniorhynchus Giles and Anopheles subpictus Grassi (Diptera:Culicidae)显示文摘 | M Govindarajan R Sivakumar M Rajeswari | 2011 | Asian Pacific Journal of Tropical Disease2011，，4： | 3 |
| 11 | Online peer and editorial recommendations, trust, and choice in virtual markets显示文摘 | Donnavieve Smith Satya Menon K. Sivakumar | 2005 | Journal of Interactive Marketing2005，，3： | 3 |
| 12 | A PERISHABLE INVENTORY SYSTEM WITH SERVICE FACILITIES, MAP ARRIVALS AND PH- SERVICE TIMES显示文摘我们认为连续评论容易腐烂(s, S ) 有由有限能力和一个单身的服务者的一个等待的大厅组成的一台服务设备的库存系统。我们假定顾客的二种类型,平常、否定,根据一个 Markovian 到达过程(地图) 到达。Anordinary 顾客加入队列,一个否定顾客把一个平常的顾客从队列移开而不是加入队列。在这篇论文采用的移动规则是 RCE (从结束的一个顾客的移动) 。单个顾客的单位需求在被假定有阶段类型分布的服务的一随机的时间以后满足。每个项目的生活时间和 reorders 的铅时间被假定是独立指数的分布。在系统和库存水平的顾客的数字的 Thejointprobability 分发为稳定的州的盒子被获得。各种各样的静止系统性能措施被计算,全部的期望的费用率是计算的。结果数字地被说明。 | Paul MANUEL B. SIVAKUMAR G. ARIVARIGNAN | 2007 | Journal of Systems Science and Systems Engineering2007，16，1： | 3 |
| 13 | HER2 expression in gastric cancer: Rare, heterogeneous and of no prognostic value – conclusions from 924 cases of two independent series显示文摘 | Heike Grabsch Shivan Sivakumar Sally Gray Helmut E. Gabbert Wolfram Müller | 2010 | Cellular Oncology (-)2010，，1： | 3 |
| 14 | Can the Grain-for-Green Program Really Ensure a Low Sediment Load on the Chinese Loess Plateau?显示文摘The Chinese Loess Plateau is the most seriously eroded area in the world and contributes the vast majority of the sediment that goes into the Yellow River.Since the 1950s,progressive soil and water conservation measures have been implemented—in particular,large-scale ecological restoration has been ongoing since 1999—resulting in a significant reduction of the sediment load.However,the mechanism of the sediment transport dynamics is not fully understood due to multiple and complicated influencing factors including climate change and human activities(e.g.,ecological restoration).A challenging question,then,arises:Is the current low sediment level a“new normal”in this era and in the future?To address this question,we selected a typical loess hilly region where considerable ecological restoration has been implemented,and which is regarded as the site of the first and most representative Grainfor-Green program in the Loess Plateau.We investigated the evolution of discharge–sediment relationships in the past decades(1960–2010)and their association with the soil and water conservation measures in this area.The results showed that there was a distinct change in the regression parameters of the commonly used annual discharge–sediment regression equation—a continuously increasing trend of parameter b and a decreasing trend of parameter a,accompanying the ecological restoration.The increase in exponent b(i.e.,a steeper slope)implies a potential lower sediment load resulting from low discharge and a potential higher sediment load resulting from large discharge.This finding may question the new normal of a low sediment level and implies the potential risk of a large sediment load during extremely wet years. | Pengcheng Sun Yiping Wu Zhifeng Yang Bellie Sivakumar Linjing Qiu Shuguang Liu Yanpeng Cai | 2019 | Engineering2019，5，5： | 3 |
| 15 | IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer显示文摘 | Sergei Grivennikov Eliad Karin Janos Terzic Daniel Mucida Guann-Yi Yu Sivakumar Vallabhapurapu Jürgen Scheller Stefan Rose-John Hilde Cheroutre Lars Eckmann Michael Karin | 2009 | Cancer Cell2009，，2： | 3 |
| 16 | Mosquito larvicidal properties of Ficus henghalensis L.(Family:Moraceae) against Culex tritaeniorhynchus Giles and Anopheles subpictus Grassi(Diptera:Culicidae)显示文摘Objective:To determine the larvicidal efficacy of different solvent leaf extract of Ficus benghalensis(F.benghalensis) against Culex tritaeniorhynchus(Cx.tritaeniorhynchus) and Anopheles subpictus(An.subpictus).Methods:Twenty five early third instar larvae of Cx. tritaeniorhynchus and An.subpictus were exposed to various concentrations and were assayed in the laboratory by using the protocol of WHO 2005.The larval mortality was observed after 24 h of treatment.Results:Among three solvent extracts tested the maximum efficacy was observed in the methanol extract.The LC50 and LC90 values of F.benghalensis against early third instar of Cx. tritaeniorhynchus and An.subpictus were 100.88.159.76 ppm and 56.66.85.84 ppm.respectively. No mortality was observed in controls.The chi-square values were significant at P<0.05 level. Conclusions:From the results it can be concluded the crude extract of F.benghalensis was an excellent potential for controlling Cx.tritaeniorhynchus and Art.subpictus mosquito larvae. | M Govindarajan R Sivakumar A Amsath S Niraimathi | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，7： | 3 |
| 17 | Stability and Hopf bifurcation analysis of a diffusive predator-prey model with Smith growth显示文摘 | M. Sivakumar M. Sambath K. Balachandran | 2015 | International Journal of Biomathematics2015，8，1： | 3 |
| 18 | Enabling Energy Efficient Sensory Data Collection Using Multiple Mobile Sink显示文摘Mobile sink is the challenging task for wireless sensor networks(WSNs).In this paper we propose to design an efficient routing protocol for single mobile sink and multiple mobile sink for data gathering in WSN.In this process,a biased random walk method is used to determine the next position of the sink.Then,a rendezvous point selection with splitting tree technique is used to find the optimal data transmission path.If the sink moves within the range of the rendezvous point,it receives the gathered data and if moved out,it selects a relay node from its neighbours to relay packets from rendezvous point to the sink.Proposed algorithm reduces the signal overhead and improves the triangular routing problem.Here the sink acts as a vehicle and collect the data from the sensor.The results show that the proposed model effectively supports sink mobility with low overhead and delay when compared with Intelligent Agent-based Routing protocol(IAR) and also increases the reliability and delivery ratio when the number of sources increases. | Madhumathy P Sivakumar D | 2014 | China Communications2014，11，10： | 3 |
| 19 | Bifurcation and spatiotemporal patterns of a density-dependent predator-prey model with Crowley-Martin functional response显示文摘 | M. Sivakumar K. Balachandran K. Karuppiah | 2017 | International Journal of Biomathematics2017，10，6： | 3 |
| 20 | Effect of quarry dust addition on the performance of controlled low-strength material made from industrial waste incineration bottom ash显示文摘The performance of industrial waste incineration bottom ash in controlled low-strength material (CLSM) was investigated in this paper, as the quarry dust was added. CLSM mixtures were made from the industrial waste incineration bottom ash, quarry dust, and cement. Tests for fresh density, bleeding, compressive strength, shear strength, hydraulic conductivity, and excavatability were carried out. The com-pressive strength ranges from 60 kPa to 6790 kPa, the friction angle varies from 5° to 19°, and the cohesion is from 4 to 604 kPa. Most of the mixtures are found to be non-excavatable. It is indicated that the quarry dust addition increases the compressive strength and shear parame-ters, decreases bleeding, and increases the removability modulus. | Naganathan Sivakumar Abdul Razak Hashim Abdul Hamid Siti Nadzriah | 2012 | International Journal of Minerals,Metallurgy and Materials2012，19，6： | 3 |
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